# NUMBER of proteins with Oi-value 6714 # NUMBER of proteins in calculation 2037 # TOTAL MOLECULES 8148000 (based on average of 4000 molecules per protein) # ID OI_VALUE PROTEINPROPHET_PROBABILITY TOTAL_SPECTRAL_COUNTS APEX_PROTEIN_ABUNDANCE NUMBER_OF_DEGENERATE_PROTEINS IDS_DEGENERATE_PROTEINS ANNOTATION YJR111C 8.08 0.84 4 581.3435 1 YJR111C YJR111C SGDID:S000003872,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondria, Chr X from 636622-635771, reverse complement, Uncharacterized ORF YFR040W 38.708 0.89 12 385.7229 1 YFR040W SAP155 SGDID:S000001936,Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap185p, and Sap190p, Chr VI from 234229-237237, Verified ORF YPL150W 35.21 0.74 1 29.3812 1 YPL150W YPL150W SGDID:S000006071,Hypothetical protein, Chr XVI from 268187-270892, Uncharacterized ORF YNL074C 13.34 1.00 5 523.9852 1 YNL074C MLF3 SGDID:S000005018,Serine-rich protein of unknown function; overproduction suppresses the growth inhibition caused by exposure to the immunosuppressant leflunomide, Chr XIV from 488125-486767, reverse complement, Verified ORF YCR088W 26.97 1.00 144 7464.2548 1 YCR088W ABP1 SGDID:S000000684,Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2\3 complex that plays a key role actin in cytoskeleton organization, Chr III from 265065-266843, Verified ORF YIL115C 63.178 1.00 7 154.8948 1 YIL115C NUP159 SGDID:S000001377,Subunit of the nuclear pore complex that is found exclusively on the cytoplasmic side, forms a subcomplex with Nup82p and Nsp1p, required for mRNA export, Chr IX from 148706-144324, reverse complement, Verified ORF YOL138C 45.158 1.00 7 216.7046 1 YOL138C YOL138C SGDID:S000005498,Hypothetical protein, Chr XV from 65350-61325, reverse complement, Uncharacterized ORF YBR267W 12.969 0.99 3 320.151 1 YBR267W REI1 SGDID:S000000471,Protein of unknown function involved in bud growth in the mitotic signaling network; proposed negative regulator of Swe1p and Gin4p; contains dispersed C2H2 zinc finger domains, Chr II from 739836-741017, Verified ORF YNL044W 5.07 1.00 10 2757.3821 1 YNL044W YIP3 SGDID:S000004989,Protein localized to COPII vesicles, proposed to be involved in ER to Golgi transport; interacts with members of the Rab GTPase family and Yip1p, Chr XIV from 545269-545292,545372-545878, Verified ORF YDR395W 26.91 1.00 19 987.0628 1 YDR395W SXM1 SGDID:S000002803,Nuclear transport factor (karyopherin) involved in protein transport between the cytoplasm and nucleoplasm; similar to Nmd5p, Cse1p, Lph2p, and the human cellular apoptosis susceptibility protein, CAS1, Chr IV from 1263316-1266150, Verified ORF YGL133W 57.888 0.95 10 229.4245 1 YGL133W ITC1 SGDID:S000003101,Component of the ATP-dependent Isw2p-Itc1p chromatin remodeling complex, required for repression of a-specific genes, repression of early meiotic genes during mitotic growth, and repression of INO1, Chr VII from 257712-261506, Verified ORF YGR129W 10.66 1.00 6 786.8626 1 YGR129W SYF2 SGDID:S000003361,Component of the spliceosome complex involved in pre-mRNA splicing; involved in regulation of cell cycle progression, Chr VII from 750405-751052, Verified ORF YER067W 4.44 0.84 8 2115.8808 1 YER067W YER067W SGDID:S000000869,Hypothetical protein, Chr V from 292064-292549, Uncharacterized ORF YGL067W 12.76 0.90 1 98.6045 1 YGL067W NPY1 SGDID:S000003035,NADH diphosphatase (pyrophosphatase), hydrolyzes the pyrophosphate linkage in NADH and related nucleotides; localizes to peroxisomes, Chr VII from 376104-377258, Verified ORF YCL050C 10.53 1.00 56 7434.7191 1 YCL050C APA1 SGDID:S000000555,Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase I (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa2p, Chr III from 38801-37836, reverse complement, Verified ORF YML048W 18.597 1.00 5 375.8651 1 YML048W GSF2 SGDID:S000004511,ER localized integral membrane protein that may promote secretion of certain hexose transporters, including Gal2p; involved in glucose-dependent repression, Chr XIII from 178426-179637, Verified ORF YCL043C 23.119 1.00 187 11307.7832 1 YCL043C PDI1 SGDID:S000000548,Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds, Chr III from 50221-48653, reverse complement, Verified ORF YNR035C 13.58 1.00 21 2161.8444 1 YNR035C ARC35 SGDID:S000005318,Subunit of the ARP2\3 complex, which is required for the motility and integrity of cortical actin patches; required for cortical localization of calmodulin, Chr XIV from 694049-693021, reverse complement, Verified ORF YBR130C 17.18 0.97 7 552.5244 1 YBR130C SHE3 SGDID:S000000334,Protein that acts as an adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; also required for cortical ER inheritance, Chr II from 496863-495586, reverse complement, Verified ORF YOL014W 2 0.95 10 6640.4654 1 YOL014W YOL014W SGDID:S000005374,Hypothetical protein, Chr XV from 299694-300068, Uncharacterized ORF YLR057W 42.454 0.93 3 91.8735 1 YLR057W YLR057W SGDID:S000004047,Putative protein of unknown function; YLR050C is not an essential gene, Chr XII from 255307-257856, Uncharacterized ORF YFR034C 9.022 0.85 1 131.7106 1 YFR034C PHO4 SGDID:S000001930,Basic helix-loop-helix (bHLH) transcription factor; binds cooperatively with Pho2p to the PHO5 promoter; function is regulated by phosphorylation at multiple sites and by phosphate availability, Chr VI from 225946-225008, reverse complement, Verified ORF YPR072W 24.278 0.89 2 102.4972 1 YPR072W NOT5 SGDID:S000006276,Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation, Chr XVI from 690104-691786, Verified ORF YMR092C 23.7 1.00 15 884.8055 1 YMR092C AIP1 SGDID:S000004698,Actin cortical patch component, interacts with the actin depolymerizing factor cofilin; required to restrict cofilin localization to cortical patches; contains WD repeats, Chr XIII from 453478-451631, reverse complement, Verified ORF YOR232W 14.065 1.00 23 2286.0883 1 YOR232W MGE1 SGDID:S000005758,Protein of the mitochondrial matrix involved in protein import into mitochondria; acts as a cochaperone and a nucleotide release factor for Ssc1p; homolog of E. coli GrpE, Chr XV from 774574-775260, Verified ORF YGL021W 35.324 0.99 7 274.2636 1 YGL021W ALK1 SGDID:S000002989,Putative Ser-Thr protein kinase, belongs to the haspin family of kinases; contains a leucine zipper motif; may function in mitosis, Chr VII from 454790-457072, Verified ORF YHL034C 13.47 1.00 61 6330.9247 1 YHL034C SBP1 SGDID:S000001026,Nucleolar single-strand nucleic acid binding protein; associates with small nuclear RNAs, Chr VIII from 34075-33191, reverse complement, Verified ORF YDR418W 7.88 1.00 209 37078.7411 2 YDR418W,YEL054C RPL12B SGDID:S000002826,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Ap; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins, Chr IV from 1301608-1302105, Verified ORF YOR317W 28.619 1.00 34 1660.846 1 YOR317W FAA1 SGDID:S000005844,Long chain fatty acyl-CoA synthetase with a preference for C12:0-C16:0 fatty acids; involved in the activation of imported fatty acids; localized to both lipid particles and mitochondrial outer membrane; essential for stationary phase, Chr XV from 909340-911442, Verified ORF YGR162W 37.4 1.00 23 859.7281 1 YGR162W TIF4631 SGDID:S000003394,Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); homologous to Tif4632p, Chr VII from 824064-826922, Verified ORF YOR109W 44.484 1.00 9 282.8417 1 YOR109W INP53 SGDID:S000005635,Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in a TGN (trans Golgi network)-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches, Chr XV from 525279-528602, Verified ORF YKL193C 15.73 0.91 1 80.8756 1 YKL193C SDS22 SGDID:S000001676,Conserved nuclear regulatory subunit of Glc7p type 1 protein serine-threonine phosphatase (PP1), functions positively with Glc7p to promote dephosphorylation of nuclear substrates required for chromosome transmission during mitosis, Chr XI from 79887-78871, reverse complement, Verified ORF YKR090W 32.138 0.98 1 42.6296 1 YKR090W PXL1 SGDID:S000001798,LIM domain-containing protein that localizes to sites of polarized growth, required for selection and\or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; has similarity to metazoan paxillin, Chr XI from 608588-610708, Verified ORF YDL066W 23.84 1.00 72 4222.1256 1 YDL066W IDP1 SGDID:S000002224,Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of isocitrate to alpha-ketoglutarate; not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes, Chr IV from 334835-336121, Verified ORF YOR162C 32.41 0.98 4 169.0876 1 YOR162C YRR1 SGDID:S000005688,Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrm1p, acting on an overlapping set of target genes, Chr XV from 641993-639561, reverse complement, Verified ORF YDL166C 11.39 0.75 8 736.4316 1 YDL166C FAP7 SGDID:S000002325,Essential NTPase required for small ribosome subunit synthesis, mediates processing of the 20S pre-rRNA at site D in the cytoplasm but associates only transiently with 43S preribosomes via Rps14p, may be the endonuclease for site D, Chr IV from 164043-163450, reverse complement, Verified ORF YGL070C 3.89 0.98 1 352.1935 1 YGL070C RPB9 SGDID:S000003038,RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription start site; involved in telomere maintenance, Chr VII from 374830-374462, reverse complement, Verified ORF YJL200C 31.209 1.00 24 1075.0689 1 YJL200C ACO2 SGDID:S000003736,Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol, Chr X from 58813-56444, reverse complement, Uncharacterized ORF YBR249C 11.49 1.00 58 7056.8823 1 YBR249C ARO4 SGDID:S000000453,3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by tyrosine, Chr II from 717989-716877, reverse complement, Verified ORF YKL010C 49.676 1.00 11 309.5643 1 YKL010C UFD4 SGDID:S000001493,Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins, Chr XI from 425518-421067, reverse complement, Verified ORF YLR045C 38.189 0.99 3 108.7234 1 YLR045C STU2 SGDID:S000004035,Microtubule-associated protein (MAP) of the XMAP215\Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p, Chr XII from 237704-235038, reverse complement, Verified ORF YJL076W 52.018 1.00 10 268.7517 1 YJL076W NET1 SGDID:S000003612,Core subunit of the RENT complex, which is a complex involved in nucleolar silencing and telophase exit; stimulates transcription by RNA polymerase I and regulates nucleolar structure, Chr X from 295162-298731, Verified ORF YPL183C 51.394 1.00 34 924.8502 1 YPL183C YPL183C SGDID:S000006104,Hypothetical protein, Chr XVI from 202535-199494, reverse complement, Uncharacterized ORF YGR003W 35.059 1.00 5 199.3771 1 YGR003W CUL3 SGDID:S000003235,Ubiquitin-protein ligase, member of the cullin family with similarity to Cdc53p and human CUL3; null mutation has no apparent phenotype, Chr VII from 500136-502370, Verified ORF YDL111C 6.09 0.98 1 224.9643 1 YDL111C RRP42 SGDID:S000002269,Protein involved in rRNA processing; component of the exosome 3- 5 exonuclease complex with Rrp4p, Rrp41p, Rrp43p and Dis3p, Chr IV from 264110-263313, reverse complement, Verified ORF YPR148C 20.81 1.00 10 671.7889 1 YPR148C YPR148C SGDID:S000006352,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern, Chr XVI from 828136-826829, reverse complement, Uncharacterized ORF YMR131C 16.73 1.00 10 835.6202 1 YMR131C RRB1 SGDID:S000004738,Essential nuclear protein involved in early steps of ribosome biogenesis; physically interacts with the ribosomal protein Rpl3p, Chr XIII from 534697-533162, reverse complement, Verified ORF YMR109W 42.679 1.00 17 556.8517 1 YMR109W MYO5 SGDID:S000004715,One of two type I myosins; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization, Chr XIII from 486586-490245, Verified ORF YGR271W 82.277 1.00 6 101.9477 1 YGR271W SLH1 SGDID:S000003503,Putative RNA helicase related to Ski2p, involved in translation inhibition of non-poly(A) mRNAs; required for repressing propagation of dsRNA viruses, Chr VII from 1031797-1037700, Verified ORF YNL251C 17.5 0.99 3 237.2593 1 YNL251C NRD1 SGDID:S000005195,RNA-binding protein that interacts with the C-terminal domain of the RNA polymerase II large subunit (Rpo21p), required for transcription termination and 3' end maturation of nonpolyadenylated RNAs, Chr XIV from 174316-172589, reverse complement, Verified ORF YGL060W 21.7 0.66 2 85.0391 1 YGL060W YBP2 SGDID:S000003028,Protein with a role in resistance to oxidative stress; has similarity to Ybp1p, which is involved in regulation of the transcription factor Yap1p via oxidation of specific cysteine residues, Chr VII from 390070-391995, Verified ORF YMR310C 10.39 0.94 2 252.9572 1 YMR310C YMR310C SGDID:S000004927,Hypothetical protein, Chr XIII from 896668-895715, reverse complement, Uncharacterized ORF YGR173W 18.59 1.00 11 827.2146 1 YGR173W RBG2 SGDID:S000003405,Protein with similarity to mammalian developmentally regulated GTP-binding protein, Chr VII from 843859-844965, Uncharacterized ORF YOL151W 19.737 0.98 1 69.4144 1 YOL151W GRE2 SGDID:S000005511,NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase); stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway, Chr XV from 43693-44721, Verified ORF YLR362W 22.947 0.99 6 361.8807 1 YLR362W STE11 SGDID:S000004354,Signal transducing MEK kinase involved in pheromone response and pseudohyphal\invasive growth pathways, where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p, Chr XII from 849865-852018, Verified ORF YBR252W 5.14 0.93 5 1264.721 1 YBR252W DUT1 SGDID:S000000456,dUTPase, catalyzes the hydrolysis of dUTP to dUMP and PPi and thereby prevents the incorporation of uracil into DNA during replication, Chr II from 722606-723049, Verified ORF YMR105C 27.46 0.99 8 403.2083 1 YMR105C PGM2 SGDID:S000004711,Phosphoglucomutase, catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism; functions as the acceptor for a Glc-phosphotransferase, Chr XIII from 477605-475896, reverse complement, Verified ORF YKL032C 6.45 0.70 1 151.7201 1 YKL032C IXR1 SGDID:S000001515,Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b, Chr XI from 381501-379708, reverse complement, Verified ORF YBR086C 27.038 0.93 4 192.3416 1 YBR086C IST2 SGDID:S000000290,Plasma membrane protein that may be involved in osmotolerance, localizes to the mother cell in small-budded cells and to the bud in medium- and large-budded cells; mRNA is transported to the bud tip by an actomyosin-driven process, Chr II from 423035-420195, reverse complement, Verified ORF YPL262W 16.54 1.00 28 2366.614 1 YPL262W FUM1 SGDID:S000006183,Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial localization determined by the N-terminal mitochondrial targeting sequence and protein conformation, Chr XVI from 47336-48802, Verified ORF YKL168C 27.85 0.76 1 38.1498 1 YKL168C KKQ8 SGDID:S000001651,Putative serine\threonine protein kinase with unknown cellular role, Chr XI from 133497-131293, reverse complement, Verified ORF YLR361C-A 3.77 0.99 8 2936.8971 1 YLR361C-A YLR361C-A SGDID:S000028845,Identified by expression profiling and mass spectrometry, Chr XII from 849678-849382, reverse complement, Uncharacterized ORF YDL202W 14.449 1.00 5 483.7679 1 YDL202W MRPL11 SGDID:S000002361,Mitochondrial ribosomal protein of the large subunit, Chr IV from 98476-99225, Verified ORF YDR104C 57.78 1.00 6 145.1705 1 YDR104C SPO71 SGDID:S000002511,Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis, Chr IV from 664907-661170, reverse complement, Verified ORF YOR027W 33.099 1.00 190 8024.9741 1 YOR027W STI1 SGDID:S000005553,Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperones; activates the ATPase activity of Ssa1p; homolog of mammalian Hop protein, Chr XV from 381053-382822, Verified ORF YJL123C 26.588 1.00 24 1261.9161 1 YJL123C YJL123C SGDID:S000003659,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to COPI-coated vesicles (early Golgi); YJL123C is a non-essential gene, Chr X from 189361-187925, reverse complement, Uncharacterized ORF YER075C 33.67 0.94 2 78.0584 1 YER075C PTP3 SGDID:S000000877,Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm, Chr V from 311195-308409, reverse complement, Verified ORF YMR086W 37.407 0.81 3 90.8151 1 YMR086W YMR086W SGDID:S000004692,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, Chr XIII from 439207-442089, Uncharacterized ORF YDR134C 0.64 0.97 10 21188.3272 2 YLR110C,YDR134C YDR134C SGDID:S000002541,Hypothetical protein, Chr IV from 721478-721068, reverse complement, pseudogene YNL071W 21.29 1.00 67 4399.5074 1 YNL071W LAT1 SGDID:S000005015,Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex, which catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA, Chr XIV from 491524-492972, Verified ORF YBR221C 15.57 1.00 41 3681.291 1 YBR221C PDB1 SGDID:S000000425,E1 beta subunit of the pyruvate dehydrogenase (PDH) complex, which is an evolutionarily-conserved multi-protein complex found in mitochondria, Chr II from 666248-665148, reverse complement, Verified ORF YBL086C 20.82 0.96 8 515.686 1 YBL086C YBL086C SGDID:S000000182,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, Chr II from 62599-61199, reverse complement, Uncharacterized ORF YGL006W 44.118 0.88 8 223.0805 1 YGL006W PMC1 SGDID:S000002974,Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium, Chr VII from 485925-489446, Verified ORF YKL204W 18.61 0.85 1 63.8524 1 YKL204W EAP1 SGDID:S000001687,eIF4E-associated protein, binds eIF4E and inhibits cap-dependent translation, also functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade, Chr XI from 53705-55603, Verified ORF YHR051W 9.33 0.67 6 602.3505 1 YHR051W COX6 SGDID:S000001093,Subunit VI of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; expression is regulated by oxygen levels, Chr VIII from 209699-210145, Verified ORF YPL171C 15.25 0.83 2 152.1749 1 YPL171C OYE3 SGDID:S000006092,Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye2p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism, Chr XVI from 227370-226168, reverse complement, Verified ORF YDL116W 27.98 0.86 9 386.7213 1 YDL116W NUP84 SGDID:S000002274,Subunit of the nuclear pore complex (NPC), forms a subcomplex with Nup85p, Nup120p, Nup145p-C, Sec13p, and Seh1p that plays a role in nuclear mRNA export and NPC biogenesis, Chr IV from 251566-253746, Verified ORF YPR124W 11.688 1.00 12 1435.3108 1 YPR124W CTR1 SGDID:S000006328,High-affinity copper transporter of the plasma membrane, mediates nearly all copper uptake under low copper conditions; transcriptionally induced at low copper levels and degraded at high copper levels, Chr XVI from 786204-787424, Verified ORF YGL167C 28.099 1.00 22 1094.5528 1 YGL167C PMR1 SGDID:S000003135,High affinity Ca2+\Mn2+ P-type ATPase required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting and processing; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease, Chr VII from 190474-187622, reverse complement, Verified ORF YHR119W 45.49 1.00 13 399.5142 1 YHR119W SET1 SGDID:S000001161,Histone methyltransferase, subunit of the COMPASS (Set1C) complex which methylates histone H3 on lysine 4; required in transcriptional silencing near telomeres and at the silent mating type loci; contains a SET domain, Chr VIII from 346046-349288, Verified ORF YLL054C 30.205 0.99 11 504.0271 1 YLL054C YLL054C SGDID:S000003977,Putative protein of unknown function with similarity to Pip2p, an oleate-specific transcriptional activator of peroxisome proliferation; YLL054C is not an essential gene, Chr XII from 35203-32894, reverse complement, Uncharacterized ORF YDL055C 16.828 1.00 318 26417.9752 1 YDL055C PSA1 SGDID:S000002213,GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure, Chr IV from 356759-355674, reverse complement, Verified ORF YNL307C 15.4 1.00 5 453.8937 1 YNL307C MCK1 SGDID:S000005251,Protein serine\threonine\tyrosine (dual-specificity) kinase involved in control of chromosome segregation and in regulating entry into meiosis; related to mammalian glycogen synthase kinases of the GSK-3 family, Chr XIV from 57573-56446, reverse complement, Verified ORF YDR378C 6.17 1.00 10 2265.7904 1 YDR378C LSM6 SGDID:S000002786,Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA, Chr IV from 1229601-1229341, reverse complement, Verified ORF YPR080W 16.899 1.00 1017 84132.7063 2 YBR118W,YPR080W TEF1 SGDID:S000006284,Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes, Chr XVI from 700592-701968, Verified ORF YOL019W 20.51 0.95 1 64.7534 1 YOL019W YOL019W SGDID:S000005379,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole, Chr XV from 288899-290554, Uncharacterized ORF YGR240C 39.77 1.00 382 13428.0418 1 YGR240C PFK1 SGDID:S000003472,Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes, Chr VII from 973739-970776, reverse complement, Verified ORF YMR295C 2.7 0.99 8 4100.7786 1 YMR295C YMR295C SGDID:S000004910,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud, Chr XIII from 858889-858296, reverse complement, Uncharacterized ORF YDR472W 12.77 1.00 3 328.4242 1 YDR472W TRS31 SGDID:S000002880,One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic, Chr IV from 1403314-1404165, Verified ORF YHL033C 9.32 1.00 326 48899.7456 1 YHL033C RPL8A SGDID:S000001025,Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Bp and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits, Chr VIII from 36023-35253, reverse complement, Verified ORF YIL142W 28.682 1.00 42 2047.1269 1 YIL142W CCT2 SGDID:S000001404,Subunit beta of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo, Chr IX from 83302-84885, Verified ORF YJR048W 6.85 1.00 3 612.2595 2 YJR048W,YEL039C CYC1 SGDID:S000003809,Cytochrome c, isoform 1; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration, Chr X from 526250-526579, Verified ORF YLR052W 11.098 0.99 1 124.7083 1 YLR052W IES3 SGDID:S000004042,Subunit of the INO80 chromatin remodeling complex, Chr XII from 247202-247954, Verified ORF YER052C 21.666 1.00 16 1032.3956 1 YER052C HOM3 SGDID:S000000854,Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis, Chr V from 257957-256374, reverse complement, Verified ORF YPR004C 15.179 1.00 9 828.904 1 YPR004C YPR004C SGDID:S000006208,Electron transfer flavoprotein complex subunit ETF-alpha; contains a FAD binding domain; interacts with YFH1, the yeast frataxin homolog, Chr XVI from 565038-564004, reverse complement, Verified ORF YPR187W 4.67 1.00 14 4190.9846 1 YPR187W RPO26 SGDID:S000006391,RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III; part of central core; similar to bacterial omega subunit, Chr XVI from 911253-911272,911349-911796, Verified ORF YOR230W 14.93 1.00 41 3839.0959 1 YOR230W WTM1 SGDID:S000005756,Transcriptional repressor involved in regulation of meiosis and silencing; contains WD repeats, Chr XV from 770801-772114, Verified ORF YOL141W 32.339 0.71 5 153.464 1 YOL141W PPM2 SGDID:S000005501,Putative carboxyl methyl transferase, has similarity to Ppm1p but biochemical activity not yet demonstrated, Chr XV from 56451-58538, Verified ORF YBR062C 4.45 0.76 2 477.5166 1 YBR062C YBR062C SGDID:S000000266,Hypothetical protein, Chr II from 366598-366583,366500-365974, reverse complement, Uncharacterized ORF YBR169C 38.18 1.00 40 1464.6335 1 YBR169C SSE2 SGDID:S000000373,Member of the heat shock protein 70 (HSP70) family; may be involved in protein folding; localized to the cytoplasm; highly homologous to the heat shock protein Sse1p, Chr II from 575991-573910, reverse complement, Verified ORF YMR031C 46.757 1.00 15 448.4866 1 YMR031C YMR031C SGDID:S000004633,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern, Chr XIII from 334742-332211, reverse complement, Uncharacterized ORF YMR285C 26.548 0.98 2 103.2117 1 YMR285C NGL2 SGDID:S000004898,Protein involved in 5.8S rRNA processing; Ccr4p-like RNase required for correct 3'-end formation of 5.8S rRNA at site E; similar to Ngl1p and Ngl3p, Chr XIII from 841690-840143, reverse complement, Verified ORF YBR279W 25.26 1.00 11 608.7854 1 YBR279W PAF1 SGDID:S000000483,RNA polymerase II-associated protein, defines a large complex that is biochemically and functionally distinct from the Srb-Mediator form of Pol II holoenzyme and is required for full expression of a subset of cell cycle-regulated genes, Chr II from 761253-762590, Verified ORF YJL221C 26.51 0.99 4 208.8287 4 YJL221C,YIL172C,YGR287C,YOL157C FSP2 SGDID:S000003757,Protein of unknown function, expression is induced during nitrogen limitation, Chr X from 18536-16767, reverse complement, Verified ORF YER096W 21.41 0.94 7 429.6493 1 YER096W SHC1 SGDID:S000000898,Sporulation-specific activator of Chs3p (chitin synthase III), required for the synthesis of the chitosan layer of ascospores; has similarity to Skt5p, which activates Chs3p during vegetative growth; transcriptionally induced at alkaline pH, Chr V from 351694-353232, Verified ORF YPL263C 24.27 1.00 4 230.4067 1 YPL263C KEL3 SGDID:S000006184,Cytoplasmic protein of unknown function, Chr XVI from 46506-44551, reverse complement, Verified ORF YIL128W 48.61 1.00 12 345.1123 1 YIL128W MET18 SGDID:S000001390,DNA repair and TFIIH regulator, required for both nucleotide excision repair (NER) and RNA polymerase II (RNAP II) transcription; involved in telomere maintenance, Chr IX from 113806-116904, Verified ORF YGR266W 30.2 0.98 4 181.4613 1 YGR266W YGR266W SGDID:S000003498,Protein of unknown function, predicted to contain a single transmembrane domain; localized to both the mitochondrial outer membrane and the plasma membrane, Chr VII from 1022662-1024767, Verified ORF YLR443W 10.77 0.97 2 251.8204 1 YLR443W ECM7 SGDID:S000004435,Non-essential protein of unknown function, Chr XII from 1022622-1023968, Verified ORF YHR155W 58.36 0.97 15 348.5399 1 YHR155W YSP1 SGDID:S000001198,Mitochondrial protein with a potential role in promoting mitochondrial fragmentation during programmed cell death in response to high levels of alpha-factor mating pheromone or the drug amiodarone, Chr VIII from 407106-410792, Uncharacterized ORF YER070W 28.3 1.00 49 2420.5527 1 YER070W RNR1 SGDID:S000000872,Ribonucleotide-diphosphate reductase (RNR), large subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits, Chr V from 298948-301614, Verified ORF YNR043W 18.59 1.00 64 4812.8851 1 YNR043W MVD1 SGDID:S000005326,Mevalonate pyrophosphate decarboxylase, essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer, Chr XIV from 701897-703087, Verified ORF YLR083C 18.55 1.00 5 376.8174 1 YLR083C EMP70 SGDID:S000004073,Protein whose 24kDa cleavage product is found in endosome-enriched membrane fractions, predicted to be a transmembrane protein, Chr XII from 296095-294092, reverse complement, Verified ORF YKL056C 6.19 1.00 191 43136.7707 1 YKL056C YKL056C SGDID:S000001539,Protein of unknown function; putative ribosomal protein; homolog of translationally controlled tumor protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YKL056C is not an essential gene, Chr XI from 334559-334056, reverse complement, Verified ORF YGR082W 7.06 0.99 5 980.179 1 YGR082W TOM20 SGDID:S000003314,Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins, Chr VII from 644048-644599, Verified ORF YBR014C 10.328 0.94 3 381.7137 1 YBR014C YBR014C SGDID:S000000218,Hypothetical protein, Chr II from 267336-266725, reverse complement, Uncharacterized ORF YPL037C 6.49 1.00 210 45235.512 1 YPL037C EGD1 SGDID:S000005958,Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b, Chr XVI from 481898-481425, reverse complement, Verified ORF YOL039W 6.66 1.00 168 35264.6814 1 YOL039W RPP2A SGDID:S000005399,Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm, Chr XV from 254296-254616, Verified ORF YGL068W 8 1.00 22 3844.48 1 YGL068W MNP1 SGDID:S000003036,Protein associated with the mitochondrial nucleoid; putative mitochondrial ribosomal protein with similarity to E. coli L7\L12 ribosomal protein; required for normal respiratory growth, Chr VII from 375090-375674, Verified ORF YLR447C 11.31 1.00 18 2224.9221 1 YLR447C VMA6 SGDID:S000004439,Subunit D of the five-subunit V0 integral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found in the endomembrane system; stabilizes VO subunits; required for V1 domain assembly on the vacuolar membrane, Chr XII from 1027890-1026853, reverse complement, Verified ORF YGL014W 19.45 0.78 2 112.1269 1 YGL014W PUF4 SGDID:S000002982,Member of the PUF protein family, which is defined by the presence of Pumilio homology domains that confer RNA binding activity; preferentially binds mRNAs encoding nucleolar ribosomal RNA-processing factors, Chr VII from 466146-468812, Verified ORF YNL209W 20.4 1.00 1401 96009.2065 1 YNL209W SSB2 SGDID:S000005153,Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p; may be involved in the folding of newly-synthesized polypeptide chains; member of the HSP70 family; homolog of SSB1, Chr XIV from 252060-253901, Verified ORF YMR113W 14.91 0.91 4 341.2939 1 YMR113W FOL3 SGDID:S000004719,Dihydrofolate synthetase, involved in folic acid biosynthesis; catalyzes the conversion of dihydropteroate to dihydrofolate in folate coenzyme biosynthesis, Chr XIII from 494998-496281, Verified ORF YDR037W 27.06 1.00 264 13638.9534 1 YDR037W KRS1 SGDID:S000002444,Lysyl-tRNA synthetase; also identified as a negative regulator of general control of amino acid biosynthesis , Chr IV from 525437-527212, Verified ORF YMR217W 22.537 1.00 163 10111.0535 1 YMR217W GUA1 SGDID:S000004830,GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation, Chr XIII from 701789-703366, Verified ORF YOR007C 19.7 1.00 79 5606.1637 1 YOR007C SGT2 SGDID:S000005533,Glutamine-rich cytoplasmic protein of unknown function, contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions; conserved in human and C. elegans, Chr XV from 339979-338939, reverse complement, Verified ORF YPR016C 4.57 1.00 24 7341.7561 1 YPR016C TIF6 SGDID:S000006220,Constituent of 66S pre-ribosomal particles, has similarity to human translation initiation factor 6 (eIF6); may be involved in the biogenesis and or stability of 60S ribosomal subunits, Chr XVI from 593066-592329, reverse complement, Verified ORF YMR296C 14.87 1.00 14 1316.2002 1 YMR296C LCB1 SGDID:S000004911,Component of serine palmitoyltransferase, responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine, Chr XIII from 860890-859214, reverse complement, Verified ORF YDR182W 10.75 1.00 4 520.1833 1 YDR182W CDC1 SGDID:S000002590,Putative membrane protein of unknown function involved in Mn2+ homeostasis; mutants display actin and general growth defects, heterogeneous cell cycle arrests, and pleiotropic defects in cell cycle progression and organelle distribution, Chr IV from 827579-829054, Verified ORF YLR060W 26.22 1.00 180 9597.204 1 YLR060W FRS1 SGDID:S000004050,Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs2p to generate the active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar, Chr XII from 260980-262767, Verified ORF YNL178W 17.75 1.00 521 41034.04 1 YNL178W RPS3 SGDID:S000005122,Protein component of the small (40S) ribosomal subunit, has apurinic\apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins, Chr XIV from 302682-303404, Verified ORF YML074C 10.41 1.00 44 5908.9029 1 YML074C FPR3 SGDID:S000004539,Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p, Chr XIII from 121324-120089, reverse complement, Verified ORF YDR232W 15.77 0.98 1 86.8758 1 YDR232W HEM1 SGDID:S000002640,5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p, Chr IV from 927448-929094, Verified ORF YDR483W 17.39 1.00 17 1366.6403 1 YDR483W KRE2 SGDID:S000002891,Alpha1,2-mannosyltransferase of the Golgi involved in protein mannosylation, Chr IV from 1421149-1422477, Verified ORF YMR019W 27.91 1.00 10 500.8931 1 YMR019W STB4 SGDID:S000004621,Protein that binds Sin3p in a two-hybrid assay; contains a Zn(II)2Cys6 zinc finger domain characteristic of DNA-binding proteins, Chr XIII from 312155-315004, Verified ORF YKL007W 12.3 0.97 5 551.241 1 YKL007W CAP1 SGDID:S000001490,Alpha subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches, Chr XI from 428945-429751, Verified ORF YCR026C 22.31 0.88 4 220.5707 1 YCR026C NPP1 SGDID:S000000621,Nucleotide pyrophosphatase\phosphodiesterase family member; mediates extracellular nucleotide phosphate hydrolysis along with Npp2p and Pho5p; activity and expression enhanced during conditions of phosphate starvation, Chr III from 166335-164107, reverse complement, Verified ORF YDL213C 9.93 0.94 7 926.3637 1 YDL213C NOP6 SGDID:S000002372,Protein with similarity to hydrophilins, which are involved in the adaptive response to hyperosmotic conditions; computational analysis of large-scale protein-protein interaction data suggests a possible role in rRNA processing, Chr IV from 77967-77290, reverse complement, Uncharacterized ORF YLR326W 6 0.74 1 172.4191 1 YLR326W YLR326W SGDID:S000004318,Hypothetical protein, Chr XII from 782174-782896, Uncharacterized ORF YMR080C 38.12 1.00 8 293.3877 1 YMR080C NAM7 SGDID:S000004685,ATP-dependent RNA helicase of the SFI superfamily, required for nonsense mediated mRNA decay and for efficient translation termination at nonsense codons; involved in telomere maintenance, Chr XIII from 429626-426711, reverse complement, Verified ORF YOR324C 27.1 1.00 5 257.9322 1 YOR324C FRT1 SGDID:S000005851,Tail-anchored endoplasmic reticulum membrane protein that is a substrate of the phosphatase calcineurin, interacts with homolog Frt2p, promotes cell growth in conditions of high Na+, alkaline pH, and cell wall stress, Chr XV from 925037-923229, reverse complement, Verified ORF YBL082C 8.638 1.00 8 1294.7374 1 YBL082C ALG3 SGDID:S000000178,Dolichol-P-Man dependent alpha(1-3) mannosyltransferase, involved in the synthesis of dolichol-linked oligosaccharide donor for N-linked glycosylation of proteins, Chr II from 71124-69748, reverse complement, Verified ORF YDR032C 7.15 1.00 59 11535.884 1 YDR032C PST2 SGDID:S000002439,Protein of unknown function with similarity to members of a family of flavodoxin-like proteins; induced by oxidative stress in a Yap1p dependent manner; GFP-fusion protein localizes to the cytoplasm in a punctate pattern, Chr IV from 504692-504096, reverse complement, Verified ORF YNL134C 14.05 1.00 10 995.0126 1 YNL134C YNL134C SGDID:S000005078,Uncharacterized ORF, Chr XIV from 373583-372453, reverse complement, Uncharacterized ORF YJL014W 25.899 1.00 21 1133.5513 1 YJL014W CCT3 SGDID:S000003551,Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo, Chr X from 407474-409078, Verified ORF YCR033W 49.09 0.82 6 140.1125 1 YCR033W SNT1 SGDID:S000000629,Subunit of the Set3C deacetylase complex; putative DNA-binding protein, Chr III from 186485-190165, Verified ORF YBL047C 45.008 1.00 29 900.7685 1 YBL047C EDE1 SGDID:S000000143,Key endocytic protein involved in a network of interactions with other endocytic proteins, binds membranes in a ubiquitin-dependent manner, may also bind ubiquitinated membrane-associated proteins, Chr II from 132043-127898, reverse complement, Verified ORF YPL012W 46.778 1.00 30 896.5706 1 YPL012W RRP12 SGDID:S000005933,Protein required for export of the ribosomal subunits; associates with the RNA components of the pre-ribosomes; contains HEAT-repeats, Chr XVI from 529720-533406, Verified ORF YER045C 10.34 0.68 1 91.9376 1 YER045C ACA1 SGDID:S000000847,Basic leucine zipper (bZIP) transcription factor of the ATF\CREB family, may regulate transcription of genes involved in utilization of non-optimal carbon sources, Chr V from 241500-240031, reverse complement, Verified ORF YKR001C 37.25 1.00 73 2739.6904 1 YKR001C VPS1 SGDID:S000001709,GTPase required for vacuolar protein sorting, functions in actin cytoskeleton organization via its interaction with Sla1p; required for late Golgi-retention of some proteins including Kex2p; involved in regulating peroxisome biogenesis, Chr XI from 442365-440251, reverse complement, Verified ORF YOR126C 11.79 0.98 1 116.2029 1 YOR126C IAH1 SGDID:S000005652,Isoamyl acetate-hydrolyzing esterase, required in balance with alcohol acetyltransferase to maintain optimal amounts of isoamyl acetate, which is particularly important in sake brewing, Chr XV from 560678-559962, reverse complement, Verified ORF YBR154C 7.32 1.00 5 954.913 1 YBR154C RPB5 SGDID:S000000358,RNA polymerase subunit ABC27, common to RNA polymerases I, II, and III; contacts DNA and affects transactivation, Chr II from 549003-548356, reverse complement, Verified ORF YJL020C 44.278 1.00 19 599.8884 1 YJL020C BBC1 SGDID:S000003557,Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p; localized predominantly to cortical actin patches, Chr X from 402327-398854, reverse complement, Verified ORF YJL047C 37.466 0.90 11 369.405 1 YJL047C RTT101 SGDID:S000003583,Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; deletion phenotype suggests a role in anaphase progression; interacts with Mms22p and implicated in Mms22-dependent DNA repair; modified by the ubiquitin-like protein, Rub1p, Chr X from 352025-349497, reverse complement, Verified ORF YPL105C 29.31 0.98 1 46.7428 1 YPL105C YPL105C SGDID:S000006026,Hypothetical protein, Chr XVI from 355409-352860, reverse complement, Uncharacterized ORF YDL167C 22.93 0.99 4 241.4326 1 YDL167C NRP1 SGDID:S000002326,Protein of unknown function, rich in asparagine residues, Chr IV from 163155-160996, reverse complement, Verified ORF YEL063C 13.348 0.95 3 298.4926 1 YEL063C CAN1 SGDID:S000000789,Plasma membrane arginine permease, requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance, Chr V from 33466-31694, reverse complement, Verified ORF YLR340W 12.6 1.00 385 42716.4444 1 YLR340W RPP0 SGDID:S000004332,Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; shown to be phosphorylated on serine 302, Chr XII from 805887-806825, Verified ORF YOR131C 10.217 1.00 4 547.3202 1 YOR131C YOR131C SGDID:S000005657,Hypothetical protein, Chr XV from 572839-572183, reverse complement, Uncharacterized ORF YDR345C 11.08 1.00 34 4289.8693 1 YDR345C HXT3 SGDID:S000002753,Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions, Chr IV from 1164654-1162951, reverse complement, Verified ORF YGL008C 17.56 1.00 450 35825.5539 1 YGL008C PMA1 SGDID:S000002976,Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plasma membrane potential; part of the P2 subgroup of cation-transporting ATPases, Chr VII from 482671-479915, reverse complement, Verified ORF YOR108W 20.09 1.00 38 2644.2868 1 YOR108W LEU9 SGDID:S000005634,Alpha-isopropylmalate synthase II (2-isopropylmalate synthase), catalyzes the first step in the leucine biosynthesis pathway; the minor isozyme, responsible for the residual alpha-IPMS activity detected in a leu4 null mutant, Chr XV from 523028-524842, Verified ORF YEL032W 50.449 0.95 1 26.3254 1 YEL032W MCM3 SGDID:S000000758,Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex, Chr V from 86937-89852, Verified ORF YLR212C 10.55 0.99 3 393.5581 1 YLR212C TUB4 SGDID:S000004202,Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and nuclear faces of the spindle pole body, Chr XII from 566283-564862, reverse complement, Verified ORF YBR222C 24.92 0.75 1 42.0744 1 YBR222C PCS60 SGDID:S000000426,Peroxisomal AMP-binding protein, localizes to both the peroxisomal peripheral membrane and matrix, expression is highly inducible by oleic acid, similar to E. coli long chain acyl-CoA synthetase, Chr II from 668346-666715, reverse complement, Verified ORF YDL095W 22.15 1.00 27 1704.0994 1 YDL095W PMT1 SGDID:S000002253,Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine\threonine residues; acts in a complex with Pmt2p, can instead interact with Pmt3p in some conditions; target for new antifungals, Chr IV from 287059-289512, Verified ORF YBR015C 29.83 0.98 6 275.5681 1 YBR015C MNN2 SGDID:S000000219,Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment, Chr II from 269503-267710, reverse complement, Verified ORF YDR361C 15.428 1.00 11 996.7539 1 YDR361C BCP1 SGDID:S000002769,Essential protein involved in nuclear export of Mss4p, which is a lipid kinase that generates phosphatidylinositol 4,5-biphosphate and plays a role in actin cytoskeleton organization and vesicular transport, Chr IV from 1196255-1195404, reverse complement, Uncharacterized ORF YOR323C 23.429 1.00 69 4117.1837 1 YOR323C PRO2 SGDID:S000005850,Gamma-glutamyl phosphate reductase, catalyzes the second step in proline biosynthesis, Chr XV from 922902-921532, reverse complement, Verified ORF YMR183C 7.8 0.99 6 1064.6252 1 YMR183C SSO2 SGDID:S000004795,Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p, Chr XIII from 627807-626920, reverse complement, Verified ORF YIL151C 37.756 0.80 2 59.2432 1 YIL151C YIL151C SGDID:S000001413,Hypothetical protein, Chr IX from 60694-57338, reverse complement, Uncharacterized ORF YPL009C 41.867 1.00 39 1302.2599 1 YPL009C YPL009C SGDID:S000005930,Hypothetical protein, Chr XVI from 538933-535817, reverse complement, Uncharacterized ORF YNL065W 15.67 0.90 5 401.4656 1 YNL065W AQR1 SGDID:S000005009,Plasma membrane transporter of the major facilitator superfamily that confers resistance to short-chain monocarboxylic acids and quinidine, Chr XIV from 503725-505485, Verified ORF YLR127C 36.058 0.98 9 341.9572 1 YLR127C APC2 SGDID:S000004117,Subunit of the Anaphase-Promoting Complex\Cyclosome (APC\C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase\anaphase transition; similar to cullin Cdc53p, Chr XII from 398320-395759, reverse complement, Verified ORF YPL063W 25.51 1.00 25 1370.0438 1 YPL063W TIM50 SGDID:S000005984,Constituent of the mitochondrial inner membrane presequence translocase (TIM23 complex); may promote binding of incoming precursor proteins to the intermembrane space domain of Tom22p during translocation, Chr XVI from 429936-431366, Verified ORF YJL222W 57.49 1.00 7 170.22 2 YJL222W,YIL173W VTH2 SGDID:S000003758,Putative membrane glycoprotein with strong similarity to Vth1p and Pep1p\Vps10p, may be involved in vacuolar protein sorting, Chr X from 11475-16124, Verified ORF YHL038C 24.218 0.88 10 507.9831 1 YHL038C CBP2 SGDID:S000001030,Mitochondrial protein required for splicing of the group I intron aI5 of the COB pre-mRNA, binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene, Chr VIII from 25506-23614, reverse complement, Verified ORF YDR457W 135.215 0.99 5 51.1782 1 YDR457W TOM1 SGDID:S000002865,E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators, Chr IV from 1369782-1379588, Verified ORF YFR024C-A 21.07 1.00 9 597.1492 1 YFR024C-A LSB3 SGDID:S000002968,Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization, Chr VI from 203421-203375,203256-201948, reverse complement, Verified ORF YOL111C 12.578 1.00 17 1889.4797 1 YOL111C MDY2 SGDID:S000005471,Nuclear protein required for efficient mating, involved in shmoo formation and nuclear migration in the pre-zygote, contains a ubiquitin-like (UBL) domain, Chr XV from 108896-108258, reverse complement, Verified ORF YER009W 3.97 1.00 35 12324.8729 1 YER009W NTF2 SGDID:S000000811,Nuclear envelope protein, interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to transport Gsp1p into the nucleus where it is an essential player in nucleocytoplasmic transport, Chr V from 172114-172491, Verified ORF YPR110C 17.34 1.00 23 1854.3156 1 YPR110C RPC40 SGDID:S000006314,RNA polymerase subunit, common to RNA polymerase I and III, Chr XVI from 746833-745826, reverse complement, Verified ORF YOR154W 21.99 0.88 3 167.8354 1 YOR154W YOR154W SGDID:S000005680,Hypothetical protein, Chr XV from 624730-626493, Uncharacterized ORF YMR219W 66.889 1.00 18 376.2033 1 YMR219W ESC1 SGDID:S000004832,Protein localized to the nuclear periphery, involved in telomeric silencing; interacts with PAD4-domain of Sir4p, Chr XIII from 707132-712108, Verified ORF YNL324W 2.77 0.74 1 373.4709 1 YNL324W YNL324W SGDID:S000005268,Hypothetical protein, Chr XIV from 31049-31444, Dubious ORF YMR238W 8.579 1.00 2 325.9104 1 YMR238W DFG5 SGDID:S000004851,Putative mannosidase, essential glycosylphosphatidylinositol (GPI)-anchored membrane protein required for cell wall biogenesis in bud formation, involved in filamentous growth, homologous to Dcw1p, Chr XIII from 746352-747728, Verified ORF YFL034C-B 12.14 0.86 3 297.1022 1 YFL034C-B MOB2 SGDID:S000001859,Component of the RAM signaling network, localizes and activates the Ace2p in the daughter cell nucleus to direct daughter cell-specific transcription of several genes involved in cell separation; Mob1p-like protein, Chr VI from 63992-63973,63858-63015, reverse complement, Verified ORF YNR016C 92.1000000000001 1.00 265 4022.4546 1 YNR016C ACC1 SGDID:S000005299,Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids, Chr XIV from 661376-654675, reverse complement, Verified ORF YER123W 18.42 0.85 1 64.511 1 YER123W YCK3 SGDID:S000000925,Palmitoylated, vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of the HOPS complex subunit, Vps41p; shares overlapping essential functions with Hrr25p, Chr V from 404809-406383, Verified ORF YBL032W 14.72 0.98 6 558.4373 1 YBL032W HEK2 SGDID:S000000128,RNA binding protein with similarity to hnRNP-K that localizes to the cytoplasm and to subtelomeric DNA; required for the proper localization of ASH1 mRNA; involved in the regulation of telomere position effect and telomere length, Chr II from 160187-161332, Verified ORF YKR054C 184.486 1.00 13 98.511 1 YKR054C DYN1 SGDID:S000001762,Cytoplasmic heavy chain dynein, microtubule motor protein, required for anaphase spindle elongation; involved in spindle assembly, chromosome movement, and spindle orientation during cell division, targeted to microtubule tips by Pac1p, Chr XI from 547567-535289, reverse complement, Verified ORF YGL105W 16.837 1.00 62 5147.9211 1 YGL105W ARC1 SGDID:S000003073,Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Gus1p), delivering tRNA to them, stimulating catalysis, and ensuring their localization to the cytoplasm; also binds quadruplex nucleic acids, Chr VII from 307440-308570, Verified ORF YMR315W 16.85 1.00 21 1742.3054 1 YMR315W YMR315W SGDID:S000004932,Hypothetical protein, Chr XIII from 902799-903848, Uncharacterized ORF YDR388W 13.92 1.00 19 1908.1797 1 YDR388W RVS167 SGDID:S000002796,Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in regulation of actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; homolog of mammalian amphiphysin, Chr IV from 1250178-1251626, Verified ORF YAL024C 71.118 0.96 5 94.3553 1 YAL024C LTE1 SGDID:S000000022,Putative GDP\GTP exchange factor required for mitotic exit at low temperatures; acts as a guanine nucleotide exchange factor (GEF) for Tem1p, which is a key regulator of mitotic exit; physically associates with Ras2p-GTP, Chr I from 105873-101566, reverse complement, Verified ORF YLR215C 19.03 0.92 2 135.1711 1 YLR215C CDC123 SGDID:S000004205,Protein involved in nutritional control of the cell cycle; regulates abundance of the translation initiation factor eIF2; ortholog of human D123 protein, Chr XII from 571860-570778, reverse complement, Verified ORF YGR090W 55.017 1.00 18 457.3835 1 YGR090W UTP22 SGDID:S000003322,Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data, Chr VII from 662362-666075, Uncharacterized ORF YOR375C 18.87 1.00 245 18150.9389 1 YOR375C GDH1 SGDID:S000005902,NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources, Chr XV from 1043040-1041676, reverse complement, Verified ORF YHR066W 13.98 0.99 1 98.9994 1 YHR066W SSF1 SGDID:S000001108,Constituent of 66S pre-ribosomal particles, required for ribosomal large subunit maturation; functionally redundant with Ssf2p; member of the Brix family, Chr VIII from 229337-230698, Verified ORF YBL022C 61.736 1.00 10 226.4469 1 YBL022C PIM1 SGDID:S000000118,Mitochondrial ATP-dependent protease involved in intramitochondrial proteolysis; involved in degradation of misfolded proteins in mitochondria; required for bigenesis and maintenance of mitochondria, Chr II from 181278-177877, reverse complement, Verified ORF YKL216W 7.78 1.00 42 7547.0044 1 YKL216W URA1 SGDID:S000001699,Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid, Chr XI from 25216-26160, Verified ORF YDR162C 7.31 0.99 6 1135.9886 1 YDR162C NBP2 SGDID:S000002569,Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex, found in the nucleus and cytoplasm, contains an SH3 domain that binds Pbs2p, Chr IV from 781097-780387, reverse complement, Verified ORF YHR088W 16.74 1.00 8 668.0968 1 YHR088W RPF1 SGDID:S000001130,Nucleolar protein involved in the assembly of the large ribosomal subunit; constituent of 66S pre-ribosomal particles; contains a sigma(70)-like motif, which is thought to bind RNA, Chr VIII from 281497-282384, Verified ORF YDL171C 91.265 1.00 104 1593.0668 1 YDL171C GLT1 SGDID:S000002330,NAD(+)-dependent glutamate synthase (GOGAT), synthesizes glutamate from glutamine and alpha-ketoglutarate; with Gln1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source, Chr IV from 155641-149204, reverse complement, Verified ORF YPR052C 5.97 1.00 22 5151.7319 1 YPR052C NHP6A SGDID:S000006256,High-mobility group non-histone chromatin protein, functionally redundant with Nhp6Bp; homologous to mammalian high mobility group proteins 1 and 2; acts to recruit transcription factor Rcs1p to certain promoters, Chr XVI from 665971-665690, reverse complement, Verified ORF YDR035W 13.65 1.00 8 819.3363 1 YDR035W ARO3 SGDID:S000002442,3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by phenylalanine, Chr IV from 521813-522925, Verified ORF YBL063W 43.7 0.81 4 103.6498 1 YBL063W KIP1 SGDID:S000000159,Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation; functionally redundant with Cin8p , Chr II from 101888-105223, Verified ORF YML094W 10.01 1.00 12 1675.9153 1 YML094W GIM5 SGDID:S000004559,Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it, Chr XIII from 82275-82290,82374-82849, Verified ORF YMR045C 60.12 0.68 1 15.8122 2 YBL005W-B,YMR045C YMR045C SGDID:S000004648,TyB Gag-Pol protein; proteolytically processed to make the Gag, RT, PR, and IN proteins that are required for retrotransposition, Chr XIII from 362626-361322,361320-357358, reverse complement, transposable_element_gene YMR049C 34.345 1.00 38 1546.7673 1 YMR049C ERB1 SGDID:S000004652,Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1, Chr XIII from 370516-368093, reverse complement, Verified ORF YER151C 36.19 1.00 11 424.9218 1 YER151C UBP3 SGDID:S000000953,Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde and retrograde transport between endoplasmic reticulum and Golgi compartments; inhibitor of gene silencing; cleaves ubiquitin fusions but not polyubiquitin, Chr V from 472419-469681, reverse complement, Verified ORF YCL039W 22.89 0.72 3 131.9206 1 YCL039W GID7 SGDID:S000000544,Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains six WD40 repeats; computational analysis suggests that Gid7p and Moh1p have similar functions, Chr III from 52645-54882, Verified ORF YHR207C 24.268 0.82 6 283.4236 1 YHR207C SET5 SGDID:S000001250,Zinc-finger protein of unknown function, contains one canonical and two unusual fingers in unusual arrangements; deletion enhances replication of positive-strand RNA virus, Chr VIII from 516485-514905, reverse complement, Verified ORF YDR171W 11.6 1.00 3 361.5498 1 YDR171W HSP42 SGDID:S000002578,Small cytosolic stress-induced chaperone that forms barrel-shaped oligomers and suppresses the aggregation of non-native proteins; oligomer dissociation is not required for function; involved in cytoskeleton reorganization after heat shock, Chr IV from 806618-807745, Verified ORF YNL126W 32.42 0.80 2 68.994 1 YNL126W SPC98 SGDID:S000005070,Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque, Chr XIV from 387229-389769, Verified ORF YPR019W 42.94 0.92 3 89.857 1 YPR019W CDC54 SGDID:S000006223,Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt the DNA prior to replication; accumulates in the nucleus in G1; homolog of S. pombe Cdc21p, Chr XVI from 596747-599548, Verified ORF YPR190C 29.64 0.98 1 46.2224 1 YPR190C RPC82 SGDID:S000006394,RNA polymerase III subunit C82, Chr XVI from 919037-917073, reverse complement, Verified ORF YNR017W 6.05 0.99 2 457.5248 1 YNR017W MAS6 SGDID:S000005300,Essential protein of the mitochondrial inner membrane, component of the mitochondrial import system, Chr XIV from 662915-663583, Verified ORF YOR258W 9.93 0.89 1 125.2984 1 YOR258W HNT3 SGDID:S000005784,Member of the third branch of the histidine triad (HIT) superfamily of nucleotide-binding proteins; similar to Aprataxin, a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia, Chr XV from 811671-812324, Verified ORF YDR353W 11.8 1.00 135 15993.9846 1 YDR353W TRR1 SGDID:S000002761,Cytoplasmic thioredoxin reductase, key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress, Chr IV from 1183292-1184251, Verified ORF YNL023C 35.5 1.00 8 315.0406 1 YNL023C FAP1 SGDID:S000004968,Protein that binds to Fpr1p (FKBP12), conferring rapamycin resistance by competing with rapamycin for Fpr1p binding; has similarity to putative transcription factors, including D. melanogaster shuttle craft and human NFX1, Chr XIV from 591161-588264, reverse complement, Verified ORF YIL015W 11.78 1.00 5 593.3755 1 YIL015W BAR1 SGDID:S000001277,Aspartyl protease secreted into the periplasmic space of mating type a cells, helps cells find mating partners, cleaves and inactivates alpha factor allowing cells to recover from alpha-factor-induced cell cycle arrest, Chr IX from 322340-324103, Verified ORF YNL052W 7.82 1.00 4 715.0857 1 YNL052W COX5A SGDID:S000004997,Subunit Va of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; predominantly expressed during aerobic growth while its isoform Vb (Cox5Bp) is expressed during anaerobic growth, Chr XIV from 531726-532187, Verified ORF YJL206C 28.8 0.78 3 113.5869 1 YJL206C YJL206C SGDID:S000003741,Putative protein of unknown function; similar to transcriptional regulators from the Zn[2]-Cys[6] binuclear cluster protein family; mRNA is weakly cell cycle regulated, peaking in S phase; induced rapidly upon MMS treatment, Chr X from 49935-47659, reverse complement, Uncharacterized ORF YKL192C 5.51 0.99 2 502.3639 1 YKL192C ACP1 SGDID:S000001675,Mitochondrial matrix acyl carrier protein, involved in biosynthesis of octanoate, which is a precursor to lipoic acid; activated by phosphopantetheinylation catalyzed by Ppt2p, Chr XI from 80542-80165, reverse complement, Verified ORF YFL018C 27.677 1.00 28 1414.3077 1 YFL018C LPD1 SGDID:S000001876,Dihydrolipoamide dehydrogenase, the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes, Chr VI from 103121-101622, reverse complement, Verified ORF YNL050C 9.18 0.77 17 1993.434 1 YNL050C YNL050C SGDID:S000004995,Hypothetical protein, Chr XIV from 534983-534967,534875-534080, reverse complement, Uncharacterized ORF YGL055W 18.77 1.00 23 1713.0438 1 YGL055W OLE1 SGDID:S000003023,Fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria, Chr VII from 398631-400163, Verified ORF YHR111W 14 1.00 4 399.4264 1 YHR111W UBA4 SGDID:S000001153,Protein that activates Urm1p before its conjugation to proteins (urmylation); one target is the thioredoxin peroxidase Ahp1p, suggesting a role of urmylation in the oxidative stress response, Chr VIII from 333075-334397, Verified ORF YNL096C 11.27 1.00 115 14265.2319 1 YNL096C RPS7B SGDID:S000005040,Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Ap; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins, Chr XIV from 444317-444174,443828-443400, reverse complement, Verified ORF YLL034C 36.754 0.99 3 112.9683 1 YLL034C RIX7 SGDID:S000003957,Putative ATPase of the AAA family, required for export of pre-ribosomal large subunits from the nucleus; distributed between the nucleolus, nucleoplasm, and nuclear periphery depending on growth conditions, Chr XII from 73145-70632, reverse complement, Verified ORF YHR019C 25.128 1.00 196 10904.4323 1 YHR019C DED81 SGDID:S000001061,Cytosolic asparaginyl-tRNA synthetase, required for protein synthesis, catalyzes the specific attachment of asparagine to its cognate tRNA, Chr VIII from 143551-141887, reverse complement, Verified ORF YHR013C 14.32 1.00 8 781.0015 1 YHR013C ARD1 SGDID:S000001055,Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing, Chr VIII from 131440-130724, reverse complement, Verified ORF YKL214C 11.03 0.99 2 250.9542 1 YKL214C YRA2 SGDID:S000001697,Member of the REF (RNA and export factor binding proteins) family; when overexpressed, can substitute for the function of Yra1p in export of poly(A)+ mRNA from the nucleus, Chr XI from 31694-31083, reverse complement, Verified ORF YNL073W 29.92 0.99 24 1110.1706 1 YNL073W MSK1 SGDID:S000005017,Mitochondrial lysine-tRNA synthetase, required for import of both aminoacylated and deacylated forms of tRNA(Lys) into mitochondria, Chr XIV from 488387-490117, Verified ORF YPL119C 31.88 0.90 4 157.8661 1 YPL119C DBP1 SGDID:S000006040,Putative ATP-dependent RNA helicase of the DEAD-box protein family; mutants show reduced stability of the 40S ribosomal subunit scanning through 5' untranslated regions of mRNAs, Chr XVI from 326263-324410, reverse complement, Verified ORF YLR075W 9.259 1.00 159 24007.0033 1 YLR075W RPL10 SGDID:S000004065,Protein component of the large (60S) ribosomal subunit, responsible for joining the 40S and 60S subunits; regulates translation initiation; has similarity to rat L10 ribosomal protein and to members of the QM gene family, Chr XII from 282928-283593, Verified ORF YDL125C 10.448 1.00 40 5352.1926 1 YDL125C HNT1 SGDID:S000002283,Adenosine 5'-monophosphoramidase; interacts physically and genetically with Kin28p, a CDK and TFIIK subunit, and genetically with CAK1; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins and similar to Hint, Chr IV from 239606-239510,239398-239019, reverse complement, Verified ORF YHR186C 62.5 1.00 18 402.6219 1 YHR186C KOG1 SGDID:S000001229,Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that contains Tor1p or Tor2p, Lst8p and Tco89p; contains four HEAT repeats and seven WD-40 repeats; may act as a scaffold protein to couple TOR and its effectors, Chr VIII from 480672-475999, reverse complement, Verified ORF YDR339C 5.25 0.75 3 599.1397 1 YDR339C YDR339C SGDID:S000002747,Nucleolar protein involved in pre-mRNA processing, Chr IV from 1150514-1149945, reverse complement, Uncharacterized ORF YNL144C 18.58 0.69 2 103.8336 1 YNL144C YNL144C SGDID:S000005088,Hypothetical protein, Chr XIV from 355044-352822, reverse complement, Uncharacterized ORF YLR435W 6.3 0.90 1 199.7132 1 YLR435W TSR2 SGDID:S000004427,Protein with a potential role in pre-rRNA processing, Chr XII from 1006375-1006992, Verified ORF YKL033W-A 10.69 1.00 7 915.4302 1 YKL033W-A YKL033W-A SGDID:S000007242,Putative protein of unknown function; similar to uncharacterized proteins from other fungi, Chr XI from 374148-374858, Uncharacterized ORF YJR092W 62.906 1.00 18 400.0233 1 YJR092W BUD4 SGDID:S000003852,Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding; potential Cdc28p substrate, Chr X from 598650-602996, Verified ORF YJL026W 17.079 1.00 39 3192.3248 1 YJL026W RNR2 SGDID:S000003563,Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits, Chr X from 392321-393520, Verified ORF YFR031C-A 8.06 1.00 133 23068.6145 2 YFR031C-A,YIL018W RPL2A SGDID:S000002104,Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and has similarity to E. coli L2 and rat L8 ribosomal proteins, Chr VI from 221406-221403,221255-220495, reverse complement, Verified ORF YDR012W 10.56 1.00 513 67913.8513 1 YDR012W RPL4B SGDID:S000002419,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl4Ap and has similarity to E. coli L4 and rat L4 ribosomal proteins, Chr IV from 471850-472938, Verified ORF YJR063W 3.35 1.00 15 6259.6689 1 YJR063W RPA12 SGDID:S000003824,RNA polymerase I subunit A12.2; contains two zinc binding domains, and the N terminal domain is responsible for anchoring to the RNA pol I complex, Chr X from 555110-555487, Verified ORF YOR278W 13.44 0.76 1 79.0531 1 YOR278W HEM4 SGDID:S000005804,Uroporphyrinogen III synthase, catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in the heme biosynthetic pathway, Chr XV from 842816-843643, Verified ORF YGR208W 13.86 0.98 4 395.3918 1 YGR208W SER2 SGDID:S000003440,Phosphoserine phosphatase of the phosphoglycerate pathway, involved in serine and glycine biosynthesis, expression is regulated by the available nitrogen source, Chr VII from 911888-912817, Verified ORF YLR078C 11.525 0.96 3 349.3465 1 YLR078C BOS1 SGDID:S000004068,v-SNARE (vesicle specific SNAP receptor), localized to the endoplasmic reticulum membrane and necessary for vesicular transport from the ER to the Golgi, Chr XII from 286560-286558,286468-285737, reverse complement, Verified ORF YIR003W 36.36 0.81 4 124.5736 1 YIR003W YIR003W SGDID:S000001442,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein colocalizes with Sac1p to the actin cytoskeleton; interacts with the SH3 domain of the actin binding protein Abp1p; YIR003W is a non-essential gene, Chr IX from 360882-362921, Uncharacterized ORF YDR201W 11.11 0.93 2 234.0473 1 YDR201W SPC19 SGDID:S000002609,Essential subunit of the DASH microtubule ring complex, couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; also localized to nuclear side of spindle pole body, Chr IV from 856314-856811, Verified ORF YIL053W 17.837 1.00 269 21083.1442 1 YIL053W RHR2 SGDID:S000001315,Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p\Gpp2p isoform, osmotic stress, Chr IX from 255113-255865, Verified ORF YPL028W 18.59 1.00 137 10302.5822 1 YPL028W ERG10 SGDID:S000005949,Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase), cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another, forming acetoacetyl-CoA; involved in the first step in mevalonate biosynthesis, Chr XVI from 498094-499290, Verified ORF YLR214W 25.15 0.95 1 52.8068 1 YLR214W FRE1 SGDID:S000004204,Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low copper and iron levels, Chr XII from 568569-570629, Verified ORF YDR258C 42 1.00 6 199.7132 1 YDR258C HSP78 SGDID:S000002666,Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochondrial thermotolerance after heat shock; prevents the aggregation of misfolded matrix proteins; component of the mitochondrial proteolysis system, Chr IV from 974239-971804, reverse complement, Verified ORF YLR027C 18.45 1.00 91 6895.2486 1 YLR027C AAT2 SGDID:S000004017,Cytosolic aspartate aminotransferase, involved in nitrogen metabolism; localizes to peroxisomes in oleate-grown cells, Chr XII from 198086-196830, reverse complement, Verified ORF YBR198C 36.263 1.00 9 346.9634 1 YBR198C TAF5 SGDID:S000000402,Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, Chr II from 618518-616122, reverse complement, Verified ORF YOR275C 30.91 0.83 3 112.6173 1 YOR275C RIM20 SGDID:S000005801,Protein involved in proteolytic activation of Rim101p in response to alkaline pH; member of the PalA\AIP1\Alix family; interacts with the ESCRT-III subunits Snf7p, suggesting a relationship between the response to pH and multivesicular body formation, Chr XV from 841068-839083, reverse complement, Verified ORF YGL245W 34.628 1.00 221 8922.1552 1 YGL245W GUS1 SGDID:S000003214,Glutamyl-tRNA synthetase (GluRS), forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p; complex formation increases the catalytic efficiency of both tRNA synthetases and ensures their correct localization to the cytoplasm, Chr VII from 39023-41149, Verified ORF YNL243W 33.66 1.00 13 539.9258 1 YNL243W SLA2 SGDID:S000005187,Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization; adaptor protein that links actin to clathrin and endocytosis; present in the actin cortical patch of the emerging bud tip; dimer in vivo, Chr XIV from 188052-190958, Verified ORF YPL209C 14 0.69 2 137.8021 1 YPL209C IPL1 SGDID:S000006130,Aurora kinase involved in regulating kinetochore-microtubule attachments, associates with Sli15p, which stimulates Ipl1p kinase activity and promotes its association with the mitotic spindle, potential Cdc28p substrate, Chr XVI from 157592-156489, reverse complement, Verified ORF YPR181C 25.76 1.00 67 3636.0835 1 YPR181C SEC23 SGDID:S000006385,GTPase-activating protein; component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat, involved in ER to Golgi transport and autophagy; stimulates the GDP-bound form of Sar1p, Chr XVI from 899663-897357, reverse complement, Verified ORF YCR084C 28.45 1.00 23 1130.1874 1 YCR084C TUP1 SGDID:S000000680,General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes, Chr III from 262449-260308, reverse complement, Verified ORF YKR060W 16.237 0.75 1 64.5744 1 YKR060W UTP30 SGDID:S000001768,Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data, Chr XI from 556160-556984, Uncharacterized ORF YKL210W 43.316 1.00 188 6067.5647 1 YKL210W UBA1 SGDID:S000001693,Ubiquitin activating enzyme, involved in ubiquitin-mediated protein degradation and essential for viability, Chr XI from 39164-42238, Verified ORF YDR508C 18.689 1.00 8 598.4237 1 YDR508C GNP1 SGDID:S000002916,High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids, Chr IV from 1468436-1466445, reverse complement, Verified ORF YBR106W 8.83 1.00 66 10449.3227 1 YBR106W PHO88 SGDID:S000000310,Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations, Chr II from 452652-453218, Verified ORF YHR018C 21.32 1.00 18 1180.294 1 YHR018C ARG4 SGDID:S000001060,Argininosuccinate lyase, catalyzes the final step in the arginine biosynthesis pathway, Chr VIII from 141395-140004, reverse complement, Verified ORF YLR318W 38.71 0.83 28 839.3012 1 YLR318W EST2 SGDID:S000004310,Reverse transcriptase subunit of the telomerase holoenzyme, essential for telomerase core catalytic activity, involved in other aspects of telomerase assembly and function; mutations in human homolog are associated with aplastic anemia, Chr XII from 766542-769196, Verified ORF YBR179C 33.906 1.00 9 371.0828 1 YBR179C FZO1 SGDID:S000000383,Mitochondrial integral membrane protein involved in mitochondrial fusion and maintenance of the mitochondrial genome; contains N-terminal GTPase domain, Chr II from 589109-586542, reverse complement, Verified ORF YFL009W 31.46 0.96 7 298.6176 1 YFL009W CDC4 SGDID:S000001885,F-box protein required for G1\S and G2\M transition, associates with Skp1p and Cdc53p to form a complex, SCFCdc4, which acts as ubiquitin-protein ligase directing ubiquitination of the phosphorylated CDK inhibitor Sic1p, Chr VI from 116139-118478, Verified ORF YKL195W 22.15 1.00 18 1136.0663 1 YKL195W MIA40 SGDID:S000001678,Essential protein of the mitochondrial intermembrane space, involved in import and assembly of intermembrane space proteins, Chr XI from 75826-77037, Verified ORF YMR039C 16.56 1.00 15 1266.2977 1 YMR039C SUB1 SGDID:S000004642,Transcriptional coactivator, facilitates elongation by influencing enzymes that modify RNAP II, acts in a peroxide resistance pathway involving Rad2p; suppressor of TFIIB mutations, Chr XIII from 349521-348643, reverse complement, Verified ORF YPL188W 9.13 0.97 3 445.5814 1 YPL188W POS5 SGDID:S000006109,Mitochondrial NADH kinase, phosphorylates NADH; also phosphorylates NAD(+) with lower specificity; required for the response to oxidative stress, Chr XVI from 191405-192649, Verified ORF YGL147C 8.47 1.00 201 33175.5063 1 YGL147C RPL9A SGDID:S000003115,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Bp and has similarity to E. coli L6 and rat L9 ribosomal proteins, Chr VII from 228334-227759, reverse complement, Verified ORF YLR257W 15.16 0.99 3 273.8811 1 YLR257W YLR257W SGDID:S000004247,Hypothetical protein, Chr XII from 658828-659793, Uncharacterized ORF YPL078C 11.749 1.00 16 1903.8116 1 YPL078C ATP4 SGDID:S000005999,Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis, Chr XVI from 408741-408007, reverse complement, Verified ORF YJR126C 33.808 0.97 5 200.552 1 YJR126C VPS70 SGDID:S000003887,Protein of unknown function involved in vacuolar protein sorting, Chr X from 658605-656170, reverse complement, Verified ORF YIL074C 20.04 1.00 16 1116.1618 1 YIL074C SER33 SGDID:S000001336,3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser3p, Chr IX from 222487-221078, reverse complement, Verified ORF YGR031W 15.19 0.66 1 60.7422 1 YGR031W YGR031W SGDID:S000003263,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion, Chr VII from 546445-547473, Uncharacterized ORF YDL145C 48.8 1.00 128 3666.8661 1 YDL145C COP1 SGDID:S000002304,Alpha subunit of COPI vesicle coatomer complex, which surrounds transport vesicles in the early secretory pathway, Chr IV from 198177-194572, reverse complement, Verified ORF YOR033C 27.731 0.98 12 592.8525 1 YOR033C EXO1 SGDID:S000005559,5'-3' exonuclease and flap-endonuclease involved in recombination, double-strand break repair and DNA mismatch repair; member of the Rad2p nuclease family, with conserved N and I nuclease domains, Chr XV from 394524-392416, reverse complement, Verified ORF YJL041W 24.66 1.00 20 1133.814 1 YJL041W NSP1 SGDID:S000003577,Essential component of the nuclear pore complex, which mediates nuclear import and export, Chr X from 365701-365701,365820-368290, Verified ORF YPR088C 24.82 1.00 9 506.9272 1 YPR088C SRP54 SGDID:S000006292,Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains the signal sequence-binding activity of SRP, interacts with the SRP RNA, and mediates binding of SRP to signal receptor; contains GTPase domain, Chr XVI from 713026-711401, reverse complement, Verified ORF YHR073W 45.54 0.86 6 158.4023 1 YHR073W OSH3 SGDID:S000001115,Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability, Chr VIII from 242584-245574, Verified ORF YPR063C 3.13 0.98 3 1313.1305 1 YPR063C YPR063C SGDID:S000006267,Hypothetical protein, Chr XVI from 678317-678277,678190-677809, reverse complement, Uncharacterized ORF YGR200C 34.26 1.00 6 244.8323 1 YGR200C ELP2 SGDID:S000003432,Elongator protein, part of the six-subunit RNA polymerase II Elongator histone acetyltransferase complex; target of Kluyveromyces lactis zymocin, Chr VII from 902275-899909, reverse complement, Verified ORF YOL007C 6.56 0.78 2 332.4494 1 YOL007C YOL007C SGDID:S000005367,Appears to be a structural component of the chitin synthase 3 complex, Chr XV from 312368-311343, reverse complement, Uncharacterized ORF YDR399W 10.26 1.00 42 5722.7772 1 YDR399W HPT1 SGDID:S000002807,Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome, Chr IV from 1270060-1270725, Verified ORF YOR197W 10.2 1.00 14 1918.8135 1 YOR197W MCA1 SGDID:S000005723,Putative cysteine protease similar to mammalian caspases, involved in regulation of apoptosis upon hydrogen peroxide treatment, Chr XV from 717024-718385, Verified ORF YDL185W 47.97 1.00 276 8043.4853 1 YDL185W TFP1 SGDID:S000002344,Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding sites; protein precursor undergoes self-catalyzed splicing to yield the extein Tfp1p and the intein Vde (PI-SceI), which is a site-specific endonuclease, Chr IV from 126788-130003, Verified ORF YER107C 9.55 0.99 5 724.614 1 YER107C GLE2 SGDID:S000000909,Component of the nuclear pore complex required for polyadenylated RNA export but not for protein import, homologous to S. pombe Rae1p, Chr V from 374541-373444, reverse complement, Verified ORF YKL024C 11.54 1.00 7 848.0025 1 YKL024C URA6 SGDID:S000001507,Uridylate kinase, catalyzes the seventh enzymatic step in the de novo biosynthesis of pyrimidines, converting uridine monophosphate (UMP) into uridine-5'-diphosphate (UDP), Chr XI from 392783-392169, reverse complement, Verified ORF YKL181W 14.65 0.94 3 269.1016 1 YKL181W PRS1 SGDID:S000001664,5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes, Chr XI from 107321-108604, Verified ORF YGL038C 17.35 0.66 1 53.1801 1 YGL038C OCH1 SGDID:S000003006,Mannosyltransferase of the cis-Golgi apparatus, initiates the polymannose outer chain elongation of N-linked oligosaccharides of glycoproteins, Chr VII from 426810-425368, reverse complement, Verified ORF YMR075W 38.34 0.94 7 239.9267 1 YMR075W YMR075W SGDID:S000004680,Nuclear protein of unknown function, Chr XIII from 413981-416035, Uncharacterized ORF YMR012W 55.229 1.00 89 2252.8264 1 YMR012W CLU1 SGDID:S000004614,eIF3 component of unknown function; deletion causes defects in mitochondrial organization but not in growth or translation initiation, can rescue cytokinesis and mitochondrial organization defects of the Dictyostelium cluA- mutant, Chr XIII from 291133-294966, Verified ORF YDR049W 29.24 0.91 1 43.5079 1 YDR049W YDR049W SGDID:S000002456,Hypothetical protein, Chr IV from 553252-555150, Uncharacterized ORF YGR192C 15.07 1.00 1229 114010.1568 1 YGR192C TDH3 SGDID:S000003424,Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall , Chr VII from 883815-882817, reverse complement, Verified ORF YDL078C 19.29 1.00 33 2391.5894 1 YDL078C MDH3 SGDID:S000002236,Cytoplasmic malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the glyoxylate cycle, Chr IV from 316388-315357, reverse complement, Verified ORF YHR200W 8.01 1.00 5 872.6546 1 YHR200W RPN10 SGDID:S000001243,Non-ATPase base subunit of the 19S regulatory particle (RP) of the 26S proteasome; N-terminus plays a role in maintaining the structural integrity of the RP; binds selectively to polyubiquitin chains; homolog of the mammalian S5a protein, Chr VIII from 499079-499885, Verified ORF YMR226C 13.02 1.00 40 4294.9085 1 YMR226C YMR226C SGDID:S000004839,NADP(+)-dependent dehydrogenase; acts on serine, L-allo-threonine, and other 3-hydroxy acids, Chr XIII from 722395-721592, reverse complement, Uncharacterized ORF YOL041C 25.23 1.00 20 1108.1987 1 YOL041C NOP12 SGDID:S000005401,Nucleolar protein, required for pre-25S rRNA processing; contains an RNA recognition motif (RRM) and has similarity to Nop13p, Nsr1p, and putative orthologs in Drosophila and S. pombe, Chr XV from 252645-251266, reverse complement, Verified ORF YJL043W 8.5 0.90 1 148.0227 1 YJL043W YJL043W SGDID:S000003579,Putative protein of unknown function; YJL043W is a non-essential gene, Chr X from 360047-360820, Uncharacterized ORF YJL052W 16.249 1.00 232 19960.2629 1 YJL052W TDH1 SGDID:S000003588,Glyceraldehyde-3-phosphate dehydrogenase, isozyme 1, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall , Chr X from 338188-339186, Verified ORF YHR023W 104.625 0.80 4 42.7582 1 YHR023W MYO1 SGDID:S000001065,Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively, Chr VIII from 151659-157445, Verified ORF YHR079C 50.54 1.00 11 304.2722 1 YHR079C IRE1 SGDID:S000001121,Serine-threonine kinase and endoribonuclease; transmembrane protein that initiates the unfolded protein response signal by regulating synthesis of Hac1p through HAC1 mRNA splicing, Chr VIII from 261593-258246, reverse complement, Verified ORF YLR006C 24.86 1.00 14 787.2847 1 YLR006C SSK1 SGDID:S000003996,Cytoplasmic response regulator, part of a two-component signal transducer that mediates osmosensing via a phosphorelay mechanism; dephosphorylated form is degraded by the ubiquitin-proteasome system; potential Cdc28p substrate, Chr XII from 163892-161754, reverse complement, Verified ORF YKL008C 11.8 0.78 3 277.229 1 YKL008C LAC1 SGDID:S000001491,Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lag1p, Chr XI from 428194-426938, reverse complement, Verified ORF YEL030W 31.07 1.00 64 2879.676 1 YEL030W ECM10 SGDID:S000000756,Heat shock protein of the Hsp70 family, localized in mitochondrial nucleoids, plays a role in protein translocation, interacts with Mge1p in an ATP-dependent manner; overexpression induces extensive mitochondrial DNA aggregations, Chr V from 94644-96578, Verified ORF YIR034C 14.12 1.00 11 1089.0878 1 YIR034C LYS1 SGDID:S000001473,Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway, Chr IX from 420733-419612, reverse complement, Verified ORF YMR291W 20.08 1.00 15 1044.3172 1 YMR291W YMR291W SGDID:S000004905,Hypothetical protein, Chr XIII from 852629-854389, Uncharacterized ORF YPL048W 17.53 1.00 108 8612.8473 1 YPL048W CAM1 SGDID:S000005969,Translational cofactor elongation factor-1 gamma, participates in the regulation of GTP-binding protein EF-1 alpha, may play a redundant role in the regulation of protein synthesis or another GTP-dependent process, Chr XVI from 464398-465645, Verified ORF YLR451W 31.907 0.97 4 170.0006 1 YLR451W LEU3 SGDID:S000004443,Zinc-finger transcription factor that regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; positively regulated by alpha-isopropylmalate, an intermediate in leucine biosynthesis, Chr XII from 1036090-1038750, Verified ORF YLR178C 8.31 1.00 4 672.9206 1 YLR178C TFS1 SGDID:S000004168,Carboxypeptidase Y inhibitor, function requires acetylation by the NatB N-terminal acetyltransferase; phosphatidylethanolamine-binding protein involved in protein kinase A signaling pathway, Chr XII from 513823-513164, reverse complement, Verified ORF YML063W 13.8 1.00 424 42952.82 1 YML063W RPS1B SGDID:S000004528,Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Ap and has similarity to rat S3a ribosomal protein, Chr XIII from 146482-147249, Verified ORF YEL046C 14.908 1.00 58 5438.9306 1 YEL046C GLY1 SGDID:S000000772,Threonine aldolase, catalyzes the cleavage of L-allo-threonine and L-threonine to glycine; involved in glycine biosynthesis, Chr V from 68792-67629, reverse complement, Verified ORF YGL120C 29.25 1.00 48 2294.1419 1 YGL120C PRP43 SGDID:S000003088,RNA helicase in the DEAH-box family, involved in release of the lariat-intron from the spliceosome, Chr VII from 283943-281640, reverse complement, Verified ORF YGR136W 6.28 1.00 13 2893.9339 1 YGR136W LSB1 SGDID:S000003368,Protein containing an N-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization, Chr VII from 762433-763158, Verified ORF YMR242C 8.86 1.00 158 24930.3443 2 YOR312C,YMR242C RPL20A SGDID:S000004855,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl20Bp and has similarity to rat L18a ribosomal protein, Chr XIII from 754196-754178,753741-753224, reverse complement, Verified ORF YDR372C 15.729 0.99 2 175.9823 1 YDR372C VPS74 SGDID:S000002780,Non-essential protein of unknown function involved in vacuolar protein sorting; belongs to a family of cytosolic Golgi-associated proteins suggesting that it may play a role in secretion; also detected in the nucleus, Chr IV from 1222141-1221104, reverse complement, Verified ORF YOR184W 19.898 1.00 79 5550.3782 1 YOR184W SER1 SGDID:S000005710,3-phosphoserine aminotransferase, catalyzes the formation of phosphoserine from 3-phosphohydroxypyruvate, required for serine and glycine biosynthesis; regulated by the general control of amino acid biosynthesis mediated by Gcn4p, Chr XV from 679358-680545, Verified ORF YER136W 19.977 1.00 37 2589.2642 1 YER136W GDI1 SGDID:S000000938,GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by regulating the dissociation of GDP from the Sec4\Ypt\rab family of GTP binding proteins, Chr V from 439612-440967, Verified ORF YGL116W 23.01 0.80 10 486.047 1 YGL116W CDC20 SGDID:S000003084,Cell-cycle regulated activator of anaphase-promoting complex\cyclosome (APC\C), which is required for metaphase\anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; potential Cdc28p substrate, Chr VII from 289812-291644, Verified ORF YMR203W 10.52 1.00 39 5182.6726 1 YMR203W TOM40 SGDID:S000004816,Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; constitutes the core element of the protein conducting pore, Chr XIII from 668491-669654, Verified ORF YLR197W 22.68 1.00 220 13560.776 1 YLR197W SIK1 SGDID:S000004187,Essential evolutionarily-conserved nucleolar protein component of the box C\D snoRNP complexes that direct 2'-O-methylation of pre-rRNA during its maturation; overexpression causes spindle orientation defects, Chr XII from 546099-547613, Verified ORF YMR145C 27.3 1.00 8 409.6681 1 YMR145C NDE1 SGDID:S000004753,Mitochondrial external NADH dehydrogenase, catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p are involved in providing the cytosolic NADH to the mitochondrial respiratory chain, Chr XIII from 556474-554792, reverse complement, Verified ORF YLL031C 19.108 0.89 2 130.2295 1 YLL031C GPI13 SGDID:S000003954,ER membrane localized phosphoryltransferase that adds phosphoethanolamine onto the third mannose residue of the glycosylphosphatidylinositol (GPI) anchor precursor; similar to human PIG-O protein, Chr XII from 80204-77151, reverse complement, Verified ORF YDR300C 22.368 1.00 14 874.9954 1 YDR300C PRO1 SGDID:S000002708,Gamma-glutamyl kinase, catalyzes the first step in proline biosynthesis, Chr IV from 1062787-1061501, reverse complement, Verified ORF YIR008C 20.32 0.99 1 68.1108 1 YIR008C PRI1 SGDID:S000001447,Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair, Chr IX from 374303-373074, reverse complement, Verified ORF YJR047C 9.217 0.95 3 432.275 1 YJR047C ANB1 SGDID:S000003808,Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Hyp2p; undergoes an essential hypusination modification; expressed under anaerobic conditions, Chr X from 525296-524823, reverse complement, Verified ORF YLR229C 4.467 0.98 2 613.4017 1 YLR229C CDC42 SGDID:S000004219,Small rho-like GTPase, essential for establishment and maintenance of cell polarity; mutants have defects in the organization of actin and septins, Chr XII from 604789-604214, reverse complement, Verified ORF YBL024W 37.15 1.00 26 978.4067 1 YBL024W NCL1 SGDID:S000000120,S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase, methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; similar to Nop2p and human proliferation associated nucleolar protein p120, Chr II from 172537-174591, Verified ORF YLR406C 6.13 1.00 108 24630.2144 2 YLR406C,YDL075W RPL31B SGDID:S000004398,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Ap and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p, Chr XII from 931754-931698,931348-931064, reverse complement, Verified ORF YJL082W 37.19 0.85 4 127.8078 1 YJL082W IML2 SGDID:S000003618,Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus, Chr X from 281102-283297, Verified ORF YLR392C 24.33 1.00 16 919.354 1 YLR392C YLR392C SGDID:S000004384,Hypothetical protein, Chr XII from 906305-904749, reverse complement, Uncharacterized ORF YGR075C 10.28 0.67 1 91.1143 1 YGR075C PRP38 SGDID:S000003307,Unique component of the U4\U6.U5 tri-snRNP particle, dispensable for spliceosome assembly, but required for conformational changes which lead to catalytic activation of the spliceosome, Chr VII from 636879-636151, reverse complement, Verified ORF YLR351C 15.246 1.00 6 550.1742 1 YLR351C NIT3 SGDID:S000004343,Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member, Chr XII from 830363-829488, reverse complement, Verified ORF YOR340C 13.55 1.00 13 1341.2476 1 YOR340C RPA43 SGDID:S000005867,RNA polymerase I subunit A43, Chr XV from 960179-959199, reverse complement, Verified ORF YDL198C 17.02 1.00 8 657.1058 1 YDL198C GGC1 SGDID:S000002357,Mitochondrial GTP\GDP transporter, essential for mitochondrial genome maintenance; has a role in mitochondrial iron transport; member of the mitochondrial carrier family; (putative) mitochondrial carrier protein, Chr IV from 104552-103650, reverse complement, Verified ORF YAL026C 48.158 0.99 1 28.739 1 YAL026C DRS2 SGDID:S000000024,Integral membrane Ca(2+)-ATPase involved in aminophospholipid translocation; required to form a specific class of secretory vesicles that accumulate upon actin cytoskeleton disruption; mutation affects maturation of the 18S rRNA, Chr I from 99698-95631, reverse complement, Verified ORF YLR001C 17.619 0.66 2 104.7363 1 YLR001C YLR001C SGDID:S000003991,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane; also found in mitochondria; YLR001C is not an essential gene, Chr XII from 153976-151388, reverse complement, Uncharacterized ORF YDR316W 22.827 0.75 23 1056.4408 1 YDR316W OMS1 SGDID:S000002724,Protein integral to the mitochondrial membrane; has a conserved methyltransferase motif; multicopy suppressor of respiratory defects caused by OXA1 mutations, Chr IV from 1093760-1095175, Verified ORF YAL003W 7.84 1.00 334 59557.3432 1 YAL003W EFB1 SGDID:S000000003,Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site, Chr I from 142176-142255,142622-143162, Verified ORF YBL008W 36.717 0.99 10 376.9406 1 YBL008W HIR1 SGDID:S000000104,Non-essential transcriptional corepressor involved in the cell cycle-regulated transcription of histone H2A, H2B, H3 and H4 genes; contributes to nucleosome formation, heterochromatic gene silencing, and formation of functional kinetochores, Chr II from 209656-212178, Verified ORF YPR033C 28.76 1.00 85 4131.7587 1 YPR033C HTS1 SGDID:S000006237,Cytoplasmic and mitochondrial histidine tRNA synthetase; encoded by a single nuclear gene that specifies two messages; efficient mitochondrial localization requires both a presequence and an amino-terminal sequence , Chr XVI from 639016-637376, reverse complement, Verified ORF YML130C 26.12 0.99 5 264.9335 1 YML130C ERO1 SGDID:S000004599,Glycoprotein required for oxidative protein folding in the endoplasmic reticulum, Chr XIII from 13175-11484, reverse complement, Verified ORF YPL049C 14.04 0.99 6 591.4584 1 YPL049C DIG1 SGDID:S000005970,Regulatory protein of unknown function, constitutively-expressed, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription, Chr XVI from 463836-462478, reverse complement, Verified ORF YJL117W 12.2 1.00 21 2406.3809 1 YJL117W PHO86 SGDID:S000003653,Endoplasmic reticulum (ER) resident protein required for ER exit of the high-affinity phosphate transporter Pho84p, specifically required for packaging of Pho84p into COPII vesicles, Chr X from 192452-193387, Verified ORF YMR162C 59.356 1.00 21 494.6062 1 YMR162C DNF3 SGDID:S000004772,Non-essential P-type ATPase involved in aminophospholipid translocation, localizes to the trans-Golgi, likely involved in protein transport, Chr XIII from 583920-578950, reverse complement, Verified ORF YHR068W 17.38 1.00 45 3619.6589 1 YHR068W DYS1 SGDID:S000001110,Deoxyhypusine synthase, catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; triggers posttranslational hypusination of translation elongation factor eIF-5A and regulates its intracellular levels; tetrameric, Chr VIII from 232135-233298, Verified ORF YDR019C 14.31 1.00 5 488.467 1 YDR019C GCV1 SGDID:S000002426,T subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm, Chr IV from 485362-484160, reverse complement, Verified ORF YNL084C 18.74 0.99 4 295.4136 1 YNL084C END3 SGDID:S000005028,EH domain-containing protein involved in endocytosis, actin cytoskeletal organization and cell wall morphogenesis; forms a complex with Sla1p and Pan1p, Chr XIV from 471104-470055, reverse complement, Verified ORF YDR430C 56.25 0.89 3 66.358 1 YDR430C CYM1 SGDID:S000002838,Lysine-specific metalloprotease of the mitochondrial intermembrane space, member of the pitrilysin family; degrades proteins and presequence peptides cleaved from imported proteins; required for normal mitochondrial morphology, Chr IV from 1328462-1325493, reverse complement, Verified ORF YDR050C 15.44 1.00 345 31237.5318 1 YDR050C TPI1 SGDID:S000002457,Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availability; transcription is controlled by activators Reb1p, Gcr1p, and Rap1p through binding sites in the 5' non-coding region, Chr IV from 556470-555724, reverse complement, Verified ORF YPR160W 39.865 0.99 4 138.8699 1 YPR160W GPH1 SGDID:S000006364,Non-essential glycogen phosphorylase required for the mobilization of glycogen, activity is regulated by cyclic AMP-mediated phosphorylation, expression is regulated by stress-response elements and by the HOG MAP kinase pathway, Chr XVI from 861302-864010, Verified ORF YOR117W 25.9 1.00 28 1511.3434 1 YOR117W RPT5 SGDID:S000005643,One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; recruited to the GAL1-10 promoter region upon induction of transcription, Chr XV from 545030-546334, Verified ORF YIL034C 12.59 1.00 15 1665.5989 1 YIL034C CAP2 SGDID:S000001296,Beta subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches, Chr IX from 290088-289225, reverse complement, Verified ORF YDR064W 13.27 1.00 232 24441.169 1 YDR064W RPS13 SGDID:S000002471,Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S15 and rat S13 ribosomal proteins, Chr IV from 579456-579476,580016-580450, Verified ORF YBL015W 22.507 1.00 14 869.5916 1 YBL015W ACH1 SGDID:S000000111,Acetyl-coA hydrolase, primarily localized to mitochondria; required for acetate utilization and for diploid pseudohyphal growth, Chr II from 194125-195705, Verified ORF YLR148W 49.31 0.81 1 22.9643 1 YLR148W PEP3 SGDID:S000004138,Vacuolar peripheral membrane protein that promotes vesicular docking\fusion reactions in conjunction with SNARE proteins, required for vacuolar biogenesis, forms complex with Pep5p that mediates protein transport to the vacuole, Chr XII from 434642-437398, Verified ORF YML068W 18.83 0.89 4 264.3045 1 YML068W ITT1 SGDID:S000004533,Protein that modulates the efficiency of translation termination, interacts with translation release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro, contains a zinc finger domain characteristic of the TRIAD class of proteins, Chr XIII from 137550-138944, Verified ORF YLR195C 21.57 0.68 1 44.072 1 YLR195C NMT1 SGDID:S000004185,N-myristoyl transferase, catalyzes the cotranslational, covalent attachment of myristic acid to the N-terminal glycine residue of several proteins involved in cellular growth and signal transduction, Chr XII from 543306-541939, reverse complement, Verified ORF YDL089W 18.648 0.99 5 371.0888 1 YDL089W YDL089W SGDID:S000002247,Protein of unknown function; interacts with meiotic division protein Csm1p; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery, potential Cdc28p substrate, Chr IV from 296820-298274, Uncharacterized ORF YIL043C 16.339 1.00 18 1540.1107 1 YIL043C CBR1 SGDID:S000001305,Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria, Chr IX from 274925-274071, reverse complement, Verified ORF YDL160C 17.54 1.00 12 956.4374 1 YDL160C DHH1 SGDID:S000002319,Cytoplasmic DExD\H-box helicase, stimulates mRNA decapping, coordinates distinct steps in mRNA function and decay, interacts with both the decapping and deadenylase complexes, may have a role in mRNA export and translation, Chr IV from 171931-170411, reverse complement, Verified ORF YFR004W 12.12 1.00 7 807.4215 1 YFR004W RPN11 SGDID:S000001900,Metalloprotease subunit of the 19S regulatory particle of the 26S proteasome lid; couples the deubiquitination and degradation of proteasome substrates, Chr VI from 153388-154308, Verified ORF YCL002C 5.4 0.95 9 2213.4884 1 YCL002C YCL002C SGDID:S000000508,Hypothetical protein, Chr III from 111674-111633,111556-110843, reverse complement, Uncharacterized ORF YDR174W 9.89 1.00 32 4523.3333 1 YDR174W HMO1 SGDID:S000002581,Chromatin associated high mobility group (HMG) family member involved in genome maintenance; rDNA-binding component of the Pol I transcription system; associates with a 5'-3' DNA helicase and Fpr1p, a prolyl isomerase, Chr IV from 812107-812847, Verified ORF YDL054C 8.55 0.82 1 134.0764 1 YDL054C MCH1 SGDID:S000002212,Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport, Chr IV from 361285-359825, reverse complement, Verified ORF YGR231C 9.039 1.00 11 1701.2855 1 YGR231C PHB2 SGDID:S000003463,Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation, Chr VII from 953483-952551, reverse complement, Verified ORF YMR266W 29.07 0.68 3 98.1047 1 YMR266W YMR266W SGDID:S000004879,Membrane protein of unknown function; overexpression suppresses NaCl sensitivity of sro7 mutant, Chr XIII from 798517-801378, Uncharacterized ORF YGR034W 6.03 1.00 21 4868.6313 1 YGR034W RPL26B SGDID:S000003266,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Ap and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA, Chr VII from 555933-555957,556312-556676, Verified ORF YPR081C 27.7 1.00 6 302.8143 1 YPR081C GRS2 SGDID:S000006285,Protein with sequence similarity to Grs1p, which is a glycyl-tRNA synthetase; cannot substitute for Grs1p; possible pseudogene that is expressed at very low levels, Chr XVI from 703968-702112, reverse complement, Verified ORF YBR026C 16.82 1.00 9 748.0341 1 YBR026C ETR1 SGDID:S000000230,2-enoyl thioester reductase, member of the medium chain dehydrogenase\reductase family; localized to in mitochondria, where it has a probable role in fatty acid synthesis, Chr II from 294019-292877, reverse complement, Verified ORF YMR125W 38.588 1.00 6 217.3721 1 YMR125W STO1 SGDID:S000004732,Large subunit of the nuclear mRNA cap-binding protein complex, interacts with Npl3p to carry nuclear poly(A)+ mRNA to cytoplasm; also involved in nuclear mRNA degradation and telomere maintenance; orthologous to mammalian CBP80, Chr XIII from 517538-517562,517885-520445, Verified ORF YGR054W 23 1.00 10 607.8229 1 YGR054W YGR054W SGDID:S000003286,Eukaryotic initiation factor (eIF) 2A; associates specifically with both 40S subunits and 80 S ribosomes, and interacts genetically with both eIF5b and eIF4E; homologous to mammalian eIF2A, Chr VII from 596697-598625, Verified ORF YML092C 11.44 1.00 32 3910.4691 1 YML092C PRE8 SGDID:S000004557,20S proteasome beta-type subunit, Chr XIII from 86739-85987, reverse complement, Verified ORF YJL105W 20.839 0.98 5 328.7184 1 YJL105W SET4 SGDID:S000003641,Protein of unknown function, contains a SET domain, Chr X from 224973-226655, Verified ORF YKL071W 12.18 0.72 4 330.5598 1 YKL071W YKL071W SGDID:S000001554,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, Chr XI from 304758-305528, Uncharacterized ORF YJR103W 21.304 0.98 7 450.161 1 YJR103W URA8 SGDID:S000003864,Minor CTP synthase isozyme (see also URA7), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis, Chr X from 620669-622363, Verified ORF YGL210W 12.94 0.99 5 534.7808 1 YGL210W YPT32 SGDID:S000003178,GTPase of the Ypt\Rab family, very similar to Ypt31p; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi, Chr VII from 93797-94465, Verified ORF YOR191W 74.394 1.00 13 244.2926 1 YOR191W RIS1 SGDID:S000005717,Member of the SWI\SNF family of DNA-dependent ATPases, plays a role in antagonizing silencing during mating-type switching, contains an N-terminal domain that interacts with Sir4p and a C-terminal SNF2 domain, Chr XV from 692476-697335, Verified ORF YGL048C 21.856 1.00 47 3006.2984 1 YGL048C RPT6 SGDID:S000003016,One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle, Chr VII from 411289-410072, reverse complement, Verified ORF YDR027C 37.125 0.65 6 146.8598 1 YDR027C VPS54 SGDID:S000002434,Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; potentially phosphorylated by Cdc28p, Chr IV from 497315-494646, reverse complement, Verified ORF YFL051C 2.32 0.99 1 596.5572 1 YFL051C YFL051C SGDID:S000001843,Putative protein of unknown function; YFL051C is not an essential gene, Chr VI from 30540-30058, reverse complement, Uncharacterized ORF YDL025C 23.469 0.86 6 307.3689 1 YDL025C YDL025C SGDID:S000002183,Protein of unknown function, potentially phosphorylated by Cdc28p, Chr IV from 407203-405341, reverse complement, Uncharacterized ORF YGR169C 19.07 0.78 6 343.0836 1 YGR169C PUS6 SGDID:S000003401,Pseudouridine synthase responsible for modification of cytoplasmic and mitochondrial tRNAs at position 31; mutation of Asp168 to Ala abolishes enzyme activity; not essential for viability, Chr VII from 835908-834694, reverse complement, Verified ORF YGR083C 18.497 1.00 10 755.7943 1 YGR083C GCD2 SGDID:S000003315,Delta subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression, Chr VII from 646819-644864, reverse complement, Verified ORF YLR293C 7.527 1.00 52 9657.9808 2 YLR293C,YOR185C GSP1 SGDID:S000004284,GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; regulated by Prp20p, Rna1p, Yrb1p, Yrb2p, Yrp4p, Yrb30p, Cse1p and Kap95p; yeast Gsp2p homolog, Chr XII from 721432-720773, reverse complement, Verified ORF YDR341C 39.916 1.00 141 4938.2947 1 YDR341C YDR341C SGDID:S000002749,Cytoplasmic arginyl-tRNA synthetase, Chr IV from 1153620-1151797, reverse complement, Verified ORF YOL022C 17.81 1.00 8 627.9585 1 YOL022C YOL022C SGDID:S000005382,Protein required for cell viability, Chr XV from 281499-280273, reverse complement, Uncharacterized ORF YGL001C 9.92 1.00 11 1550.1935 1 YGL001C ERG26 SGDID:S000002969,C-3 sterol dehydrogenase, catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis, Chr VII from 496506-495457, reverse complement, Verified ORF YHR031C 40.19 0.99 25 860.9186 1 YHR031C RRM3 SGDID:S000001073,DNA helicase involved in rDNA replication and Ty1 transposition; structurally and functionally related to Pif1p, Chr VIII from 172963-170792, reverse complement, Verified ORF YLR256W-A 8.47 1.00 8 1320.4181 13 YML040W,YPR158C-C,YLR227W-A,YGR027W-A,YDR098C-A,YLR157C-A,YLR256W-A,YOL103W-A,YGR038C-A,YJR026W,YPL257W-A,YDR365W-A,YER137C-A YLR256W-A SGDID:S000007377,TyA Gag protein; the main structural constituent of virus-like particles (VLPs), Chr XII from 651119-652441, transposable_element_gene YLL011W 17.46 0.96 2 153.7311 1 YLL011W SOF1 SGDID:S000003934,Essential subunit of the U3 (box C+D) snRNP complex required for 2' O-methylation of pre-RNA; has similarity to the beta subunit of trimeric G-proteins and the splicing factor Prp4p, Chr XII from 127522-128991, Verified ORF YGL090W 22.798 0.88 3 161.887 1 YGL090W LIF1 SGDID:S000003058,Protein involved in DNA double-strand break repair; physically interacts with DNA ligase 4 (Lig4p); homologous to mammalian XRCC4 protein, Chr VII from 343322-344587, Verified ORF YML026C 7.58 1.00 239 44079.1902 2 YDR450W,YML026C RPS18B SGDID:S000004488,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Ap and has similarity to E. coli S13 and rat S18 ribosomal proteins, Chr XIII from 223828-223782,223380-222987, reverse complement, Verified ORF YLR189C 43.34 1.00 10 322.564 1 YLR189C ATG26 SGDID:S000004179,UDP-glucose:sterol glucosyltransferase, conserved enzyme involved in synthesis of sterol glucoside membrane lipids, involved in autophagy, Chr XII from 534395-530799, reverse complement, Verified ORF YHL020C 16.98 0.87 9 644.6574 1 YHL020C OPI1 SGDID:S000001012,Transcriptional regulator of a variety of genes; phosphorylation by protein kinase A stimulates Opi1p function in negative regulation of phospholipid biosynthetic genes; involved in telomere maintenance, Chr VIII from 67453-66239, reverse complement, Verified ORF YFL028C 16.188 0.97 1 83.769 1 YFL028C CAF16 SGDID:S000001866,Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation; putative ABC ATPase; interacts with Ssn2p, Ssn3p, and Ssn8p, Chr VI from 80211-79342, reverse complement, Verified ORF YBR256C 10.2 1.00 7 959.4067 1 YBR256C RIB5 SGDID:S000000460,Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway, Chr II from 728097-727381, reverse complement, Verified ORF YNL229C 10.11 0.98 2 271.0252 1 YNL229C URE2 SGDID:S000005173,Nitrogen catabolite repression regulator that acts by inhibition of GLN3 transcription in good nitrogen source; altered form of Ure2p creates [URE3] prion, Chr XIV from 220202-219138, reverse complement, Verified ORF YOR081C 27.236 0.99 9 457.3401 1 YOR081C TGL5 SGDID:S000005607,Triacylglycerol lipase involved in TAG mobilization; localizes to lipid particles; potential Cdc28p substrate, Chr XV from 479190-476941, reverse complement, Verified ORF YLR452C 25.908 0.95 8 410.0951 1 YLR452C SST2 SGDID:S000004444,GTPase-activating protein for Gpa1p, regulates desensitization to alpha factor pheromone; also required to prevent receptor-independent signaling of the mating pathway; member of the RGS (regulator of G-protein signaling) family, Chr XII from 1041364-1039268, reverse complement, Verified ORF YGR279C 10.6 0.99 12 1566.8069 1 YGR279C SCW4 SGDID:S000003511,Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating, Chr VII from 1049964-1048804, reverse complement, Verified ORF YGL123W 12.62 1.00 237 26253.9046 1 YGL123W RPS2 SGDID:S000003091,Protein component of the small (40S) subunit, essential for control of translational accuracy; has similarity to E. coli S5 and rat S2 ribosomal proteins, Chr VII from 277623-278387, Verified ORF YMR005W 16.73 0.67 1 55.9865 1 YMR005W TAF4 SGDID:S000004607,TFIID subunit (48 kDa), involved in RNA polymerase II transcription initiation; potential Cdc28p substrate, Chr XIII from 276045-277211, Verified ORF YKL122C 5.46 1.00 14 3584.5967 1 YKL122C SRP21 SGDID:S000001605,Subunit of the signal recognition particle (SRP), which functions in protein targeting to the endoplasmic reticulum membrane; not found in mammalian SRP; forms a pre-SRP structure in the nucleolus that is translocated to the cytoplasm, Chr XI from 212642-212139, reverse complement, Verified ORF YML118W 20.588 0.82 1 55.6806 1 YML118W NGL3 SGDID:S000004587,Putative endonuclease, has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; similar to Ngl1p and Ngl2p, Chr XIII from 32334-33851, Verified ORF YDL080C 20.79 1.00 4 268.974 1 YDL080C THI3 SGDID:S000002238,Probable decarboxylase, required for expression of enzymes involved in thiamine biosynthesis; may have a role in catabolism of amino acids to long-chain and complex alcohols, Chr IV from 312471-310642, reverse complement, Verified ORF YMR062C 24.34 1.00 8 459.4881 1 YMR062C ECM40 SGDID:S000004666,Mitochondrial ornithine acetyltransferase, catalyzes the fifth step in arginine biosynthesis; also possesses acetylglutamate synthase activity, regenerates acetylglutamate while forming ornithine, Chr XIII from 396378-395053, reverse complement, Verified ORF YDR368W 20.459 1.00 64 4373.2115 1 YDR368W YPR1 SGDID:S000002776,2-methylbutyraldehyde reductase, may be involved in isoleucine catabolism, Chr IV from 1213896-1214834, Verified ORF YEL001C 2.15 0.70 1 455.1604 1 YEL001C YEL001C SGDID:S000000727,Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; YEL001C is non-essential, Chr V from 150977-150300, reverse complement, Uncharacterized ORF YJR134C 37.69 0.66 2 48.9612 1 YJR134C SGM1 SGDID:S000003895,Protein of unknown function, required for wild-type growth rate on galactose and mannose; localizes to COPI coated vesicles and the Golgi apparatus, Chr X from 675768-673645, reverse complement, Verified ORF YOL109W 6.16 1.00 74 16794.0684 1 YOL109W ZEO1 SGDID:S000005469,Peripheral membrane protein of the plasma membrane that interacts with Mid2p; regulates the cell integrity pathway mediated by Pkc1p and Slt2p, Chr XV from 110297-110638, Verified ORF YLR179C 9.55 1.00 47 6880.1736 1 YLR179C YLR179C SGDID:S000004169,Protein of unknown function, transcription is activated by paralogous proteins Yrm1p and Yrr1p along with proteins involved in multidrug resistance; GFP-tagged protein localizes to the cytoplasm and nucleus; YLR179C is not essential, Chr XII from 514715-514110, reverse complement, Uncharacterized ORF YDL034W 4.55 0.73 3 672.88 1 YDL034W YDL034W SGDID:S000002192,Hypothetical protein, Chr IV from 391780-392124, Dubious ORF YAR007C 26.98 1.00 51 2642.6104 1 YAR007C RFA1 SGDID:S000000065,Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination, Chr I from 158621-156756, reverse complement, Verified ORF YPL061W 30.46 1.00 360 16522.5667 1 YPL061W ALD6 SGDID:S000005982,Cytosolic aldehyde dehydrogenase that is activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for the conversion of acetaldehyde to acetate; constitutively expressed, Chr XVI from 432585-434087, Verified ORF YJL060W 22.59 0.84 1 51.9837 1 YJL060W BNA3 SGDID:S000003596,Arylformamidase, involved in biosynthesis of nicotinic acid from tryptophan via kynurenine pathway; potential Cdc28p substrate, Chr X from 323303-324637, Verified ORF YPR062W 5.848 1.00 11 2629.6032 1 YPR062W FCY1 SGDID:S000006266,Cytosine deaminase, zinc metalloenzyme that catalyzes the hydrolytic deamination of cytosine to uracil; of biomedical interest because it also catalyzes the deamination of 5-fluorocytosine (5FC) to form anticancer drug 5-fluorouracil (5FU), Chr XVI from 677162-677638, Verified ORF YLR208W 13.287 1.00 35 3682.5276 1 YLR208W SEC13 SGDID:S000004198,Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (Sar1p, Sec13p, Sec16p, Sec23p, Sec24p, Sec31p, Sfb2p, and Sfb3p) which is important for the formation of ER to Golgi transport vesicles, Chr XII from 559553-560446, Verified ORF YDR165W 23.55 1.00 25 1484.0687 1 YDR165W TRM82 SGDID:S000002572,Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA, Chr IV from 784868-786202, Verified ORF YMR222C 4.53 0.94 2 580.1824 1 YMR222C FSH2 SGDID:S000004835,Serine hydrolase that localizes to both the nucleus and cytoplasm; sequence is similar to Fsh1p and Fsh3p, Chr XIII from 716308-715637, reverse complement, Verified ORF YML078W 9.899 0.99 5 699.0669 1 YML078W CPR3 SGDID:S000004543,Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; involved in protein refolding after import into mitochondria, Chr XIII from 111002-111550, Verified ORF YMR146C 15.348 1.00 73 6649.3008 1 YMR146C TIF34 SGDID:S000004754,Subunit of the core complex of translation initiation factor 3(eIF3), which is essential for translation, Chr XIII from 558523-557480, reverse complement, Verified ORF YDR128W 45.639 1.00 5 153.1576 1 YDR128W YDR128W SGDID:S000002535,Hypothetical protein, Chr IV from 709546-712992, Uncharacterized ORF YML085C 13.59 1.00 24 2468.8613 1 YML085C TUB1 SGDID:S000004550,Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules, Chr XIII from 99400-99376,99259-97941, reverse complement, Verified ORF YDR326C 50.758 0.99 4 109.0675 1 YDR326C YDR326C SGDID:S000002734,Hypothetical protein, Chr IV from 1124920-1120604, reverse complement, Uncharacterized ORF YLR330W 18.06 0.97 9 675.7738 1 YLR330W CHS5 SGDID:S000004322,Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p localization, also involved in cell fusion during mating, Chr XII from 787664-789679, Verified ORF YPL198W 11.42 1.00 416 50925.1291 2 YPL198W,YGL076C RPL7B SGDID:S000006119,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Ap and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2), Chr XVI from 173151-173161,173571-173664,174072-174701, Verified ORF YGL062W 46.899 0.94 3 84.0602 1 YGL062W PYC1 SGDID:S000003030,Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis, Chr VII from 385199-388735, Verified ORF YER080W 42.13 1.00 8 265.4626 1 YER080W YER080W SGDID:S000000882,The authentic, non-tagged protein was localized to the mitochondria, Chr V from 319959-321842, Uncharacterized ORF YHR179W 16.98 1.00 241 19841.9462 1 YHR179W OYE2 SGDID:S000001222,Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye3p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism, Chr VIII from 462502-463704, Verified ORF YER057C 4.48 1.00 33 10297.7142 1 YER057C HMF1 SGDID:S000000859,Member of the p14.5 protein family with similarity to Mmf1p, functionally complements Mmf1p function when targeted to mitochondria; heat shock inducible; high-dosage growth inhibitor; forms a homotrimer in vitro, Chr V from 271124-270735, reverse complement, Verified ORF YCR087C-A 4.768 0.97 2 568.8141 1 YCR087C-A YCR087C-A SGDID:S000007223,Hypothetical protein, Chr III from 264464-264003, reverse complement, Uncharacterized ORF YOR116C 67.014 0.99 12 247.8311 1 YOR116C RPO31 SGDID:S000005642,RNA polymerase III subunit C160, part of core enzyme; similar to bacterial beta-prime subunit, Chr XV from 544146-539764, reverse complement, Verified ORF YBL074C 14.76 0.85 5 402.5385 1 YBL074C AAR2 SGDID:S000000170,Component of the U5 snRNP, required for splicing of U3 precursors; originally described as a splicing factor specifically required for splicing pre-mRNA of the MATa1 cistron, Chr II from 87787-86720, reverse complement, Verified ORF YLR029C 6.18 1.00 93 21037.7546 1 YLR029C RPL15A SGDID:S000004019,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Bp and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA, Chr XII from 202591-201977, reverse complement, Verified ORF YLR337C 21.59 1.00 3 194.2555 1 YLR337C VRP1 SGDID:S000004329,Proline-rich, actin-associated protein involved in cytoskeletal organization and cytokinesis; related to mammalian Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP), Chr XII from 805106-802653, reverse complement, Verified ORF YDR060W 49.979 1.00 27 755.2332 1 YDR060W MAK21 SGDID:S000002467,Constituent of 66S pre-ribosomal particles, required for large (60S) ribosomal subunit biogenesis; involved in nuclear export of pre-ribosomes; required for maintenance of dsRNA virus; homolog of human CAATT-binding protein, Chr IV from 570646-573723, Verified ORF YMR155W 10.69 0.76 4 397.5582 1 YMR155W YMR155W SGDID:S000004764,Hypothetical protein, Chr XIII from 568550-570193, Uncharacterized ORF YKL093W 13.38 1.00 7 731.3863 1 YKL093W MBR1 SGDID:S000001576,Protein involved in mitochondrial functions and stress response; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants, Chr XI from 264433-265452, Verified ORF YML088W 20.36 0.99 7 475.8393 1 YML088W UFO1 SGDID:S000004553,F-box receptor protein, subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex; binds to phosphorylated Ho endonuclease, allowing its ubiquitylation by SCF and subsequent degradation, Chr XIII from 92235-94241, Verified ORF YDR195W 26.94 0.98 3 152.5649 1 YDR195W REF2 SGDID:S000002603,RNA-binding protein involved in the cleavage step of mRNA 3'-end formation prior to polyadenylation, and in snoRNA maturation; part of holo-CPF subcomplex APT, which associates with 3'-ends of snoRNA- and mRNA-encoding genes, Chr IV from 848596-850197, Verified ORF YDL101C 19.137 1.00 8 584.4145 1 YDL101C DUN1 SGDID:S000002259,Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2\M arrest after DNA damage; also regulates postreplicative DNA repair, Chr IV from 281848-280307, reverse complement, Verified ORF YIL140W 26.55 0.71 2 74.7702 1 YIL140W AXL2 SGDID:S000001402,Integral plasma membrane protein required for axial budding in haploid cells, localizes to the incipient bud site and bud neck; glycosylated by Pmt4p; potential Cdc28p substrate, Chr IX from 85366-87837, Verified ORF YDL102W 51.224 1.00 13 354.7927 1 YDL102W CDC2 SGDID:S000002260,Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replication during mitosis and meiosis, intragenic recombination, repair of double strand DNA breaks, and DNA replication during nucleotide excision repair (NER), Chr IV from 276872-280165, Verified ORF YER008C 52.998 0.88 9 208.9154 1 YER008C SEC3 SGDID:S000000810,Non-essential subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which mediates targeting of post-Golgi vesicles to sites of active exocytosis; Sec3p specifically is a spatial landmark for secretion, Chr V from 171817-167807, reverse complement, Verified ORF YBR126C 16.45 1.00 7 594.8905 1 YBR126C TPS1 SGDID:S000000330,Synthase subunit of trehalose-6-phosphate synthase\phosphatase complex, which synthesizes the storage carbohydrate trehalose; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway, Chr II from 490386-488899, reverse complement, Verified ORF YBL026W 6.25 0.97 4 867.8738 1 YBL026W LSM2 SGDID:S000000122,Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA, Chr II from 170626-170679,170808-171041, Verified ORF YKL142W 16.94 1.00 27 2228.2056 1 YKL142W MRP8 SGDID:S000001625,Putative mitochondrial ribosomal protein, has similarity to E. coli ribosomal protein S2, Chr XI from 178520-179179, Verified ORF YNR021W 11.73 1.00 7 834.2667 1 YNR021W YNR021W SGDID:S000005304,Hypothetical protein, Chr XIV from 668379-669593, Uncharacterized ORF YGR080W 12.1 0.96 2 221.8302 1 YGR080W TWF1 SGDID:S000003312,Twinfilin, highly conserved actin monomer-sequestering protein involved in regulation of the cortical actin cytoskeleton, composed of two cofilin-like regions, localizes actin monomers to sites of rapid filament assembly, Chr VII from 642014-643012, Verified ORF YIL110W 10.699 0.98 1 128.0524 1 YIL110W YIL110W SGDID:S000001372,Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; deletion mutant exhibits a weak vacuolar protein sorting defect and enhanced resistance to the glucan synthase inhibitor caspofungin, Chr IX from 156042-157175, Uncharacterized ORF YDL141W 27.325 0.91 5 232.7856 1 YDL141W BPL1 SGDID:S000002300,Biotin:apoprotein ligase, covalently modifies proteins with the addition of biotin, required for acetyl-CoA carboxylase (Acc1p) holoenzyme formation, Chr IV from 203040-205112, Verified ORF YBL055C 22.108 0.99 11 688.6258 1 YBL055C YBL055C SGDID:S000000151,Hypothetical protein, Chr II from 116832-115576, reverse complement, Uncharacterized ORF YDR429C 11 1.00 67 8515.0466 1 YDR429C TIF35 SGDID:S000002837,Subunit of the core complex of translation initiation factor 3(eIF3), which is essential for translation, Chr IV from 1325293-1324469, reverse complement, Verified ORF YOR004W 10.4 0.87 2 233.8949 1 YOR004W YOR004W SGDID:S000005530,Protein required for cell viability, Chr XV from 333593-334357, Uncharacterized ORF YML010W 44.869 1.00 24 747.7729 1 YML010W SPT5 SGDID:S000004470,Protein that forms a complex with Spt4p and mediates both activation and inhibition of transcription elongation; Spt4p-Spt5p complex also plays a role in pre-mRNA processing, Chr XIII from 247677-250868, Verified ORF YPL191C 8.98 0.82 14 1787.1889 1 YPL191C YPL191C SGDID:S000006112,Hypothetical protein, Chr XVI from 184678-183596, reverse complement, Uncharacterized ORF YMR013C 9.16 1.00 15 2289.2894 1 YMR013C SEC59 SGDID:S000004615,Dolichol kinase, catalyzes the terminal step in dolichyl monophosphate (Dol-P) biosynthesis; required for viability and for normal rates of lipid intermediate synthesis and protein N-glycosylation, Chr XIII from 296737-295178, reverse complement, Verified ORF YLL010C 11.45 0.84 3 307.6804 1 YLL010C PSR1 SGDID:S000003933,Plasma membrane associated protein phosphatase involved in the general stress response; required along with binding partner Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p, Chr XII from 130612-129329, reverse complement, Verified ORF YLR272C 47.96 1.00 12 349.7896 1 YLR272C YCS4 SGDID:S000004262,Non-SMC subunit of the condensin complex (Smc2p-Smc4p-Ycs4p-Brn1p-Ycg1p); required for establishment and maintenance of chromosome condensation, chromosome segregation, chromatin binding of condensin and silencing at the mating type locus, Chr XII from 687204-683674, reverse complement, Verified ORF YNL104C 20.78 1.00 66 4440.2078 1 YNL104C LEU4 SGDID:S000005048,Alpha-isopropylmalate synthase (2-isopropylmalate synthase); the main isozyme responsible for the first step in the leucine biosynthesis pathway, Chr XIV from 426756-424897, reverse complement, Verified ORF YIL005W 32.82 0.91 2 77.5242 1 YIL005W EPS1 SGDID:S000001267,Pdi1p (protein disulfide isomerase)-related protein involved in endoplasmic reticulum retention of resident ER proteins, Chr IX from 345689-347794, Verified ORF YOR365C 16.178 0.76 6 394.0441 1 YOR365C YOR365C SGDID:S000005892,Hypothetical protein, Chr XV from 1025570-1023459, reverse complement, Uncharacterized ORF YFL038C 11.74 1.00 22 2619.7478 1 YFL038C YPT1 SGDID:S000001856,Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p), Chr VI from 55985-55365, reverse complement, Verified ORF YKR056W 32.759 0.72 1 30.726 1 YKR056W TRM2 SGDID:S000001764,tRNA methyltransferase, 5-methylates the uridine residue at position 54 of tRNAs and may also have a role in tRNA stabilization or maturation; previously thought to be an endo-exonuclease, Chr XI from 549090-551009, Verified ORF YPL237W 20.125 1.00 29 2014.4988 1 YPL237W SUI3 SGDID:S000006158,Beta subunit of the translation initiation factor eIF2, involved in the identification of the start codon; proposed to be involved in mRNA binding, Chr XVI from 100496-101353, Verified ORF YPL240C 27.23 1.00 807 41431.5142 1 YPL240C HSP82 SGDID:S000006161,Cytoplasmic chaperone (Hsp90 family) required for pheromone signaling and negative regulation of Hsf1p; docks with the mitochondrial import receptor Tom70p for preprotein delivery; interacts with co-chaperones Cns1p, Cpr6p, Cpr7p, and Sti1p, Chr XVI from 98625-96496, reverse complement, Verified ORF YNR030W 13.049 0.73 1 78.2078 1 YNR030W ALG12 SGDID:S000005313,Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition of the alpha-1,6 mannose to dolichol-linked Man7GlcNAc2, acts in the dolichol pathway for N-glycosylation, Chr XIV from 678801-680456, Verified ORF YHR069C 13.46 0.97 1 100.7468 1 YHR069C RRP4 SGDID:S000001111,Protein involved in rRNA processing; component of the exosome 3- 5 exonuclease complex with Rrp41p, Rrp42p, Rrp43p and Dis3p, Chr VIII from 234660-233581, reverse complement, Verified ORF YER167W 19.88 0.96 10 675.087 1 YER167W BCK2 SGDID:S000000969,Protein rich in serine and threonine residues involved in protein kinase C signaling pathway, which controls cell integrity; overproduction suppresses pkc1 mutations, Chr V from 518211-520766, Verified ORF YPL053C 20.92 1.00 3 200.4769 1 YPL053C KTR6 SGDID:S000005974,Probable mannosylphosphate transferase involved in the synthesis of core oligosaccharides in protein glycosylation pathway; member of the KRE2\MNT1 mannosyltransferase family, Chr XVI from 458455-457115, reverse complement, Verified ORF YJR070C 16.36 1.00 134 11450.5516 1 YJR070C LIA1 SGDID:S000003831,Deoxyhypusine hydroxylase, a HEAT-repeat containing metalloenzyme that catalyses hypusine formation; binds to and is required for the modification of Hyp2p (eIF5A); complements S. pombe mmd1 mutants defective in mitochondrial positioning, Chr X from 570513-569536, reverse complement, Verified ORF YBR265W 8.83 0.73 38 4391.882 1 YBR265W TSC10 SGDID:S000000469,3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis, essential for growth in the absence of exogenous dihydrosphingosine or phytosphingosine, member of short chain dehydrogenase\reductase protein family, Chr II from 738577-739539, Verified ORF YDL143W 21.58 1.00 40 2591.2747 1 YDL143W CCT4 SGDID:S000002302,Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo, Chr IV from 199997-201583, Verified ORF YPL231W 85.007 1.00 461 7581.4303 1 YPL231W FAS2 SGDID:S000006152,Alpha subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains beta-ketoacyl reductase and beta-ketoacyl synthase activities, Chr XVI from 108652-114315, Verified ORF YMR290C 28.05 1.00 39 1943.7332 1 YMR290C HAS1 SGDID:S000004903,ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles, Chr XIII from 851590-850073, reverse complement, Verified ORF YHR021C 2.68 0.99 7 3614.9588 2 YKL156W,YHR021C RPS27B SGDID:S000001063,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Ap and has similarity to rat S27 ribosomal protein, Chr VIII from 148662-148660,148109-147864, reverse complement, Verified ORF YNR040W 11 0.97 1 123.2775 1 YNR040W YNR040W SGDID:S000005323,Hypothetical protein, Chr XIV from 699692-700462, Uncharacterized ORF YLL045C 9.23999999999999 1.00 375 56736.7178 1 YLL045C RPL8B SGDID:S000003968,Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits, Chr XII from 48628-47858, reverse complement, Verified ORF YNL048W 27.919 0.74 3 111.1624 1 YNL048W ALG11 SGDID:S000004993,Alpha-1,2-mannosyltransferase, catalyzes addition of the terminal alpha 1,2-Man to the Man5GlcNAc2-PP-dolichol intermediate during asparagine-linked glycosylation in the ER, Chr XIV from 538174-539820, Verified ORF YNR034W 16.637 0.95 2 159.6553 1 YNR034W SOL1 SGDID:S000005317,Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol2p, Sol3p, and Sol4p, Chr XIV from 690323-691288, Verified ORF YDL045C 13.22 0.88 2 186.117 1 YDL045C FAD1 SGDID:S000002203,Flavin adenine dinucleotide (FAD) synthetase, performs the second step in synthesis of FAD from riboflavin, Chr IV from 373605-372685, reverse complement, Verified ORF YPL211W 8.67 0.96 12 1857.5405 1 YPL211W NIP7 SGDID:S000006132,Nucleolar protein required for 60S ribosome subunit biogenesis, constituent of 66S pre-ribosomal particles; physically interacts with Nop8p and the exosome subunit Rrp43p, Chr XVI from 153494-154039, Verified ORF YAL038W 39.19 1.00 1286 45874.4233 1 YAL038W CDC19 SGDID:S000000036,Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration, Chr I from 71787-73289, Verified ORF YDR087C 12.65 0.98 1 108.3029 1 YDR087C RRP1 SGDID:S000002494,Essential evolutionarily conserved nucleolar protein necessary for biogenesis of 60S ribosomal subunits and processing of pre-rRNAs to mature rRNAs, associated with several distinct 66S pre-ribosomal particles, Chr IV from 618303-617467, reverse complement, Verified ORF YML012W 6.79 0.84 2 345.8951 1 YML012W ERV25 SGDID:S000004473,Protein that forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, member of the p24 family involved in endoplasmic reticulum to Golgi transport, Chr XIII from 246116-246751, Verified ORF YGL104C 4.46 0.75 1 235.0884 1 YGL104C VPS73 SGDID:S000003072,Mitochondrial protein of unknown function involved in vacuolar protein sorting, Chr VII from 310176-308716, reverse complement, Verified ORF YGR128C 28.899 1.00 4 193.5004 1 YGR128C UTP8 SGDID:S000003360,Nucleolar protein required for export of tRNAs from the nucleus; also copurifies with the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA, Chr VII from 750096-747955, reverse complement, Verified ORF YHR124W 29.758 1.00 28 1315.4041 1 YHR124W NDT80 SGDID:S000001166,Meiosis-specific transcription factor required for exit from pachytene and for full meiotic recombination; activates middle sporulation genes; competes with Sum1p for binding to promoters containing middle sporulation elements (MSE), Chr VIII from 356564-358447, Verified ORF YPL210C 26.147 1.00 6 320.7999 1 YPL210C SRP72 SGDID:S000006131,Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane, Chr XVI from 156211-154289, reverse complement, Verified ORF Q0250 5.23 0.98 6 1571.7394 1 Q0250 COX2 SGDID:S000007281,Subunit II of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits, Chr Mito from 73758-74513, Verified ORF YGR130C 34.02 1.00 3 123.2797 1 YGR130C YGR130C SGDID:S000003362,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; specifically phosphorylated in vitro by mammalian diphosphoinositol pentakisphosphate (IP7), Chr VII from 753849-751399, reverse complement, Uncharacterized ORF YBL060W 25.09 0.91 14 709.8615 1 YBL060W YBL060W SGDID:S000000156,Hypothetical protein, Chr II from 107934-109997, Uncharacterized ORF YHL025W 7.37 0.88 4 667.698 1 YHL025W SNF6 SGDID:S000001017,Subunit of the SWI\SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p, Chr VIII from 54849-55847, Verified ORF YOR206W 30.25 1.00 32 1478.8683 1 YOR206W NOC2 SGDID:S000005732,Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre-ribosomes, as well as a nuclear complex with Noc3p that binds to 66S pre-ribosomes; both complexes mediate intranuclear transport of ribosomal precursors, Chr XV from 727513-729645, Verified ORF YDR164C 35.286 1.00 4 158.4756 1 YDR164C SEC1 SGDID:S000002571,Sm-like protein involved in docking and fusion of exocytic vesicles through binding to assembled SNARE complexes at the membrane; localization to sites of secretion (bud neck and bud tip) is dependent on SNARE function, Chr IV from 784212-782038, reverse complement, Verified ORF YGR155W 39.968 1.00 353 12347.1635 1 YGR155W CYS4 SGDID:S000003387,Cystathionine beta-synthase, catalyzes the synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis, Chr VII from 798548-800071, Verified ORF YER103W 27.229 0.99 5 254.1431 1 YER103W SSA4 SGDID:S000000905,Heat shock protein that is highly induced upon stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the HSP70 family; cytoplasmic protein that concentrates in nuclei upon starvation, Chr V from 364585-366513, Verified ORF YCR067C 26.97 1.00 7 362.8457 1 YCR067C SED4 SGDID:S000000663,Integral endoplasmic reticulum membrane protein, functions as a positive regulator of Sar1p probably through inhibition of GTPase activation by Sec23p; binds Sec16p, participates in vesicle formation, similar to Sec12p, Chr III from 236318-233121, reverse complement, Verified ORF YDL132W 40.726 0.98 6 201.8415 1 YDL132W CDC53 SGDID:S000002290,Cullin, structural protein of SCF complexes (which also contain Skp1p, Cdc34p, and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation, Chr IV from 224304-226751, Verified ORF YDR464W 54.58 1.00 40 1024.5457 1 YDR464W SPP41 SGDID:S000002872,Protein involved in negative regulation of expression of spliceosome components PRP4 and PRP3, Chr IV from 1388864-1393171, Verified ORF YGR056W 34.255 0.69 5 140.7991 1 YGR056W RSC1 SGDID:S000003288,One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; required for expression of mid-late sporulation-specific genes; contains two essential bromodomains, a bromo-adjacent homology (BAH) domain, and an AT hook, Chr VII from 601665-604451, Verified ORF YGR210C 22.036 1.00 9 570.9717 1 YGR210C YGR210C SGDID:S000003442,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, Chr VII from 914743-913508, reverse complement, Uncharacterized ORF YOR168W 46.736 1.00 98 2931.4294 1 YOR168W GLN4 SGDID:S000005694,Glutamine tRNA synthetase, monomeric class I tRNA synthetase that catalyzes the specific glutaminylation of tRNA(Glu); N-terminal domain proposed to be involved in enzyme-tRNA interactions, Chr XV from 649304-651733, Verified ORF YKR015C 28.12 0.82 1 40.7665 1 YKR015C YKR015C SGDID:S000001723,Putative protein of unknown function, Chr XI from 468310-466604, reverse complement, Uncharacterized ORF YOR128C 25.92 1.00 9 485.4141 1 YOR128C ADE2 SGDID:S000005654,Phosphoribosylaminoimidazole carboxylase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway; red pigment accumulates in mutant cells deprived of adenine, Chr XV from 566192-564477, reverse complement, Verified ORF YAL063C 7.18 0.95 2 369.9423 1 YAL063C FLO9 SGDID:S000000059,Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation, Chr I from 27969-24001, reverse complement, Verified ORF YDL060W 28.247 1.00 13 643.3924 1 YDL060W TSR1 SGDID:S000002218,Protein required for processing of 20S pre-rRNA in the cytoplasm, associates with pre-40S ribosomal particles, Chr IV from 341619-343985, Verified ORF YFR016C 73.6799999999999 0.75 1 14.2303 1 YFR016C YFR016C SGDID:S000001912,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and bud; interacts with Spa2p; YFL016C is not an essential gene, Chr VI from 180735-177034, reverse complement, Verified ORF YIL069C 6.13 1.00 264 60207.1909 2 YIL069C,YER074W RPS24B SGDID:S000001331,Protein component of the small (40S) ribosomal subunit; identical to Rps24Ap and has similarity to rat S24 ribosomal protein, Chr IX from 232366-232364,231954-231550, reverse complement, Verified ORF YJR065C 17.83 1.00 15 1176.1015 1 YJR065C ARP3 SGDID:S000003826,Essential component of the Arp2\3 complex, which is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity, Chr X from 559073-557724, reverse complement, Verified ORF YIL085C 17.23 1.00 5 405.6856 1 YIL085C KTR7 SGDID:S000001347,Putative mannosyltransferase involved in protein glycosylation; member of the KRE2\MNT1 mannosyltransferase family, Chr IX from 202040-200487, reverse complement, Verified ORF YNL002C 12.119 1.00 11 1268.9099 1 YNL002C RLP7 SGDID:S000004947,Nucleolar protein with similarity to large ribosomal subunit L7 proteins; constituent of 66S pre-ribosomal particles; plays an essential role in processing of precursors to the large ribosomal subunit RNAs, Chr XIV from 627144-626176, reverse complement, Verified ORF YOR086C 48.709 1.00 8 229.6072 1 YOR086C TCB1 SGDID:S000005612,Contains three calcium and lipid binding domains; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; C-terminal portion of Tcb1p, Tcb2p and Tcb3p interact, Chr XV from 486781-483221, reverse complement, Verified ORF YGL195W 120.039 1.00 149 1735.277 1 YGL195W GCN1 SGDID:S000003163,Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p; proposed to stimulate Gcn2p activation by an uncharged tRNA, Chr VII from 131531-139549, Verified ORF YJL209W 28.478 0.95 7 326.4503 1 YJL209W CBP1 SGDID:S000003745,Mitochondrial protein that interacts with the 5'-untranslated region of the COB mRNA and has a role in its stability and translation; found in a complex at the inner membrane along with Pet309p, Chr X from 38005-39969, Verified ORF YHR193C 8.038 1.00 129 22436.0614 1 YHR193C EGD2 SGDID:S000001236,Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) involved in protein sorting and translocation, associated with cytoplasmic ribosomes , Chr VIII from 488236-487712, reverse complement, Verified ORF YMR173W-A 9.08 0.73 2 224.7873 1 YMR173W-A YMR173W-A SGDID:S000004785,Hypothetical protein, Chr XIII from 608896-610080, Dubious ORF YJR105W 12.44 1.00 151 16969.2043 1 YJR105W ADO1 SGDID:S000003866,Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle, Chr X from 623495-624517, Verified ORF YOR005C 43.345 0.99 6 191.5809 1 YOR005C DNL4 SGDID:S000005531,DNA ligase required for nonhomologous end-joining (NHEJ), forms stable heterodimer with required cofactor Lif1p, catalyzes DNA ligation as part of a complex with Lif1p and Nej1p; involved in meiosis, not essential for vegetative growth, Chr XV from 337344-334510, reverse complement, Verified ORF YLR413W 9.15 1.00 16 2444.5774 1 YLR413W YLR413W SGDID:S000004405,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, Chr XII from 951153-953180, Uncharacterized ORF YOR354C 27.14 1.00 6 309.0625 1 YOR354C MSC6 SGDID:S000005881,Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to mitochondria; msc6 mutants are defective in directing meiotic recombination events to homologous chromatids, Chr XV from 1003222-1001144, reverse complement, Verified ORF YER161C 13.87 0.79 2 159.2522 1 YER161C SPT2 SGDID:S000000963,Protein involved in negative regulation of transcription, exhibits regulated interactions with both histones and SWI-SNF components, has similarity to mammalian HMG1 proteins, Chr V from 500343-499342, reverse complement, Verified ORF YMR143W 8.81 1.00 72 11425.1392 2 YMR143W,YDL083C RPS16A SGDID:S000004751,Protein component of the small (40S) ribosomal subunit; identical to Rps16Bp and has similarity to E. coli S9 and rat S16 ribosomal proteins, Chr XIII from 551927-551950,552495-552902, Verified ORF YBR092C 10.14 0.99 2 272.9808 1 YBR092C PHO3 SGDID:S000000296,Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin, Chr II from 429095-427692, reverse complement, Verified ORF YGR175C 17.78 0.97 9 686.416 1 YGR175C ERG1 SGDID:S000003407,Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine, Chr VII from 848428-846938, reverse complement, Verified ORF YBR087W 15.307 0.99 3 271.2509 1 YBR087W RFC5 SGDID:S000000291,Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon, Chr II from 423759-424823, Verified ORF YCR081W 56.594 1.00 36 889.2769 1 YCR081W SRB8 SGDID:S000000677,Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in glucose repression, Chr III from 254368-258651, Verified ORF YLR429W 31.12 1.00 35 1572.2925 1 YLR429W CRN1 SGDID:S000004421,Coronin, cortical actin cytoskeletal component that associates with the Arp2p\Arp3p complex to regulate its activity, Chr XII from 990774-992729, Verified ORF YGL242C 6.47 0.99 1 213.9123 1 YGL242C YGL242C SGDID:S000003211,Putative protein of unknown function; deletion mutant is viable, Chr VII from 45197-44652, reverse complement, Uncharacterized ORF YDR539W 18.71 0.97 1 72.4774 1 YDR539W YDR539W SGDID:S000002947,Hypothetical protein, Chr IV from 1512084-1513595, Uncharacterized ORF YKL211C 18.95 1.00 10 737.727 1 YKL211C TRP3 SGDID:S000001694,Bifunctional enzyme exhibiting both indole-3-glycerol-phosphate synthase and anthranilate synthase activities, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp2p, Chr XI from 38154-36700, reverse complement, Verified ORF YMR111C 23.809 0.84 3 147.9668 1 YMR111C YMR111C SGDID:S000004717,Hypothetical protein, Chr XIII from 493791-492403, reverse complement, Uncharacterized ORF YJL176C 39.396 0.70 1 24.8399 1 YJL176C SWI3 SGDID:S000003712,Subunit of the SWI\SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2, Chr X from 94528-92051, reverse complement, Verified ORF YHR001W 21.15 0.96 4 253.8199 1 YHR001W OSH7 SGDID:S000001043,Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability, Chr VIII from 106050-107363, Verified ORF YHR128W 11.11 1.00 46 5788.2687 1 YHR128W FUR1 SGDID:S000001170,Uracil phosphoribosyltransferase, synthesizes UMP from uracil; involved in the pyrimidine salvage pathway, Chr VIII from 362118-362768, Verified ORF YDR225W 3.19 1.00 102 44700.7079 2 YBL003C,YDR225W HTA1 SGDID:S000002633,One of two nearly identical (see also HTA2) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p , Chr IV from 915526-915924, Verified ORF YMR192W 42.816 1.00 6 195.907 1 YMR192W GYL1 SGDID:S000004804,Putative GTPase activating protein (GAP) that may have a role in polarized exocytosis; stimulates Gyp5p GAP activity on Ypt1p, colocalizes with Gyp5p at sites of polarized growth; interacts with Gyp5p, Rvs161p, and Rvs167p, Chr XIII from 647117-649279, Verified ORF YNR061C 4.82 0.96 5 1392.1919 1 YNR061C YNR061C SGDID:S000005344,Hypothetical protein, Chr XIV from 743540-742881, reverse complement, Uncharacterized ORF YLR274W 36.929 0.97 8 293.7643 1 YLR274W CDC46 SGDID:S000004264,Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase, Chr XII from 691557-693884, Verified ORF YGR119C 11.729 0.95 2 226.4631 1 YGR119C NUP57 SGDID:S000003351,Essential subunit of the nuclear pore complex (NPC), functions as the organizing center of an NPC subcomplex containing Nsp1p, Nup49p, Nup57p, and Nic96p, Chr VII from 729676-728051, reverse complement, Verified ORF YBR009C 5.43 1.00 79 20339.1207 2 YNL030W,YBR009C HHF1 SGDID:S000000213,One of two identical histone H4 proteins (see also HHF2); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity, Chr II from 255682-255371, reverse complement, Verified ORF YJL056C 19.25 0.65 4 188.8197 1 YJL056C ZAP1 SGDID:S000003592,Zinc-regulated transcription factor, binds to zinc-responsive promoter elements to induce transcription of certain genes in the presence of zinc; regulates its own transcription; contains seven zinc-finger domains, Chr X from 332990-330348, reverse complement, Verified ORF YDL103C 29.77 1.00 6 281.7586 1 YDL103C QRI1 SGDID:S000002261,UDP-N-acetylglucosamine pyrophosphorylase, catalyzes the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is important in cell wall biosynthesis, protein N-glycosylation, and GPI anchor biosynthesis, Chr IV from 276581-275148, reverse complement, Verified ORF YPR189W 65.0379999999999 1.00 10 214.9501 1 YPR189W SKI3 SGDID:S000006393,Protein involved in exosome mediated 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs; forms complex with Ski2p and Ski8p; required for repressing propagation of dsRNA viruses, Chr XVI from 912660-916958, Verified ORF YGL135W 10.04 1.00 176 24506.6454 2 YPL220W,YGL135W RPL1B SGDID:S000003103,N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1Bp and has similarity to E. coli L1 and rat L10a ribosomal proteins; rpl1a rpl1b double null mutation is lethal, Chr VII from 254646-255299, Verified ORF YJL122W 7.11 1.00 13 2556.1048 1 YJL122W YJL122W SGDID:S000003658,Hypothetical protein, Chr X from 189637-190164, Uncharacterized ORF YBL058W 19.45 1.00 11 790.6385 1 YBL058W SHP1 SGDID:S000000154,UBX (ubiquitin regulatory X) domain-containing protein that regulates Glc7p phosphatase activity and interacts with Cdc48p; interacts with ubiquitylated proteins in vivo and is required for degradation of a ubiquitylated model substrate, Chr II from 111439-112710, Verified ORF YBR048W 6.94 1.00 15 3021.5981 2 YDR025W,YBR048W RPS11B SGDID:S000000252,Protein component of the small (40S) ribosomal subunit; identical to Rps11Ap and has similarity to E. coli S17 and rat S11 ribosomal proteins, Chr II from 332829-332873,333385-333810, Verified ORF YCL017C 20.249 1.00 7 483.2806 1 YCL017C NFS1 SGDID:S000000522,Cysteine desulfurase involved in iron-sulfur cluster (Fe\S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria, Chr III from 94270-92777, reverse complement, Verified ORF YGL236C 25.642 0.70 2 76.3275 1 YGL236C MTO1 SGDID:S000003205,Mitochondrial protein, forms a heterodimer complex with Mss1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; required for respiration in paromomycin-resistant 15S rRNA mutants, Chr VII from 55796-53787, reverse complement, Verified ORF YMR186W 27.379 1.00 847 43248.4693 1 YMR186W HSC82 SGDID:S000004798,Cytoplasmic chaperone of the Hsp90 family, redundant in function and nearly identical with Hsp82p, and together they are essential; expressed constitutively at 10-fold higher basal levels that HSP82 and induced 2-3 fold by heat shock, Chr XIII from 632354-634471, Verified ORF YOL132W 15.38 0.88 3 239.9675 1 YOL132W GAS4 SGDID:S000005492,Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall, Chr XV from 71300-72715, Verified ORF YNL154C 17.848 1.00 13 1018.26 1 YNL154C YCK2 SGDID:S000005098,Palmitoylated, plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking; provides an essential function overlapping with that of Yck1p, Chr XIV from 345278-343638, reverse complement, Verified ORF YGR209C 8.1 1.00 46 7939.2179 1 YGR209C TRX2 SGDID:S000003441,Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against both oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance, Chr VII from 913232-912918, reverse complement, Verified ORF YBL064C 13.52 1.00 18 1861.2329 1 YBL064C PRX1 SGDID:S000000160,Mitochondrial peroxiredoxin (1-Cys Prx) with thioredoxin peroxidase activity, has a role in reduction of hydroperoxides; induced during respiratory growth and under conditions of oxidative stress, Chr II from 101158-100373, reverse complement, Verified ORF YNR048W 11.37 0.98 1 120.4954 1 YNR048W YNR048W SGDID:S000005331,Protein proposed to interact with phospholipid translocases, shares similarity to Cdc50p, Chr XIV from 711632-712813, Verified ORF YLR002C 27.97 0.96 1 47.9825 1 YLR002C NOC3 SGDID:S000003992,Protein that forms a nuclear complex with Noc2p that binds to 66S ribosomal precursors to mediate their intranuclear transport; also binds to chromatin to promote the association of DNA replication factors and replication initiation, Chr XII from 156333-154342, reverse complement, Verified ORF YFL045C 12.697 1.00 108 11891.251 1 YFL045C SEC53 SGDID:S000001849,Phosphomannomutase, involved in synthesis of GDP-mannose and dolichol-phosphate-mannose; required for folding and glycosylation of secretory proteins in the ER lumen, Chr VI from 44392-43628, reverse complement, Verified ORF YLL023C 9.05 0.83 1 128.2136 1 YLL023C YLL023C SGDID:S000003946,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YLL023C is not an essential gene, Chr XII from 98835-97996, reverse complement, Uncharacterized ORF YPR091C 46.067 1.00 5 151.7347 1 YPR091C YPR091C SGDID:S000006295,Hypothetical protein, Chr XVI from 718466-716154, reverse complement, Uncharacterized ORF YGR204W 37.42 1.00 129 4819.3763 1 YGR204W ADE3 SGDID:S000003436,Cytoplasmic trifunctional enzyme C1-tetrahydrofolate synthase, involved in single carbon metabolism and required for biosynthesis of purines, thymidylate, methionine, and histidine, Chr VII from 905939-908779, Verified ORF YKL029C 24.46 1.00 33 1886.0899 1 YKL029C MAE1 SGDID:S000001512,Mitochondrial malic enzyme, catalyzes the oxidative decarboxylation of malate to pyruvate, which is a key intermediate in sugar metabolism and a precursor for synthesis of several amino acids, Chr XI from 384368-382359, reverse complement, Verified ORF YNL039W 26.4 1.00 28 1482.7195 1 YNL039W BDP1 SGDID:S000004984,Essential subunit of RNA polymerase III transcription factor (TFIIIB), which is involved in transcription of genes encoding tRNAs, 5S rRNA, U6 snRNA, and other small RNAs, Chr XIV from 555049-556833, Verified ORF YLR271W 14.59 0.82 4 314.2848 1 YLR271W YLR271W SGDID:S000004261,Hypothetical protein, Chr XII from 682739-683563, Uncharacterized ORF YDL149W 34.45 0.85 3 103.4798 1 YDL149W ATG9 SGDID:S000002308,Transmembrane protein involved in formation of Cvt and autophagic vesicles; cycles between the pre-autophagosomal structure and other cytosolic punctate structures, not found in autophagosomes, Chr IV from 184926-187919, Verified ORF YNL249C 23.806 0.70 2 82.2141 1 YNL249C MPA43 SGDID:S000005193,Mitochondrial protein of unknown function, Chr XIV from 181023-179395, reverse complement, Verified ORF YGR187C 18.837 0.99 19 1395.9889 1 YGR187C HGH1 SGDID:S000003419,Protein of unknown function with similarity to human HMG1 and HMG2; localizes to the cytoplasm, Chr VII from 871421-870237, reverse complement, Verified ORF YEL020W-A 3.07 0.89 1 405.2812 1 YEL020W-A TIM9 SGDID:S000007256,Mitochondrial intermembrane space protein, forms a complex with Mrs11p\Tim10p that mediates import and insertion of a subset of polytopic inner membrane proteins; may prevent aggregation of incoming proteins in a chaperone-like manner, Chr V from 117211-117474, Verified ORF YKR038C 18.55 0.94 3 212.525 1 YKR038C KAE1 SGDID:S000001746,Putative glycoprotease that interacts with Bud32p, which is a member of the novel protein kinase piD261 family, Chr XI from 512801-511641, reverse complement, Verified ORF YJL069C 12.36 0.99 5 559.8757 1 YJL069C UTP18 SGDID:S000003605,Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data, Chr X from 312623-310839, reverse complement, Uncharacterized ORF YGL054C 2.808 0.87 3 1299.4163 1 YGL054C ERV14 SGDID:S000003022,Protein localized to COPII-coated vesicles, involved in vesicle formation and incorporation of specific secretory cargo; required for the delivery of bud-site selection protein Axl2p to cell surface; related to Drosophila cornichon, Chr VII from 401290-400874, reverse complement, Verified ORF YER060W 6.49 0.68 1 146.4768 1 YER060W FCY21 SGDID:S000000862,Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function, Chr V from 274565-276151, Verified ORF YJR016C 24.86 1.00 284 15970.6329 1 YJR016C ILV3 SGDID:S000003777,Dihydroxyacid dehydratase, catalyzes third step in the common pathway leading to biosynthesis of branched-chain amino acids, Chr X from 466123-464366, reverse complement, Verified ORF YLR354C 24.586 1.00 146 8301.7545 1 YLR354C TAL1 SGDID:S000004346,Transaldolase, enzyme in the non-oxidative pentose phosphate pathway; converts sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate to erythrose 4-phosphate and fructose 6-phosphate, Chr XII from 837356-836349, reverse complement, Verified ORF YDR176W 35.1 0.99 1 39.4305 1 YDR176W NGG1 SGDID:S000002583,Transcriptional regulator involved in glucose repression of Gal4p-regulated genes; component of transcriptional adaptor and histone acetyltransferase complexes, the ADA complex, the SAGA complex, and the SLIK complex, Chr IV from 814449-816557, Verified ORF YGL009C 31.113 1.00 184 8267.6264 1 YGL009C LEU1 SGDID:S000002977,Isopropylmalate isomerase, catalyzes the second step in the leucine biosynthesis pathway, Chr VII from 478657-476318, reverse complement, Verified ORF YDR222W 20.28 1.00 5 344.6727 1 YDR222W YDR222W SGDID:S000002630,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern, Chr IV from 910050-911297, Uncharacterized ORF YIL008W 2.31 0.98 20 11861.7564 1 YIL008W URM1 SGDID:S000001270,Ubiquitin-like protein with only weak sequence similarity to ubiquitin; depends on the E1-like activating enzyme Uba4p; molecular function of the Urm1p pathway is unknown, but it is required for normal growth, particularly at high temperature, Chr IX from 342533-342832, Verified ORF YPR115W 55.828 1.00 7 175.2874 1 YPR115W YPR115W SGDID:S000006319,Hypothetical protein, Chr XVI from 754875-758126, Uncharacterized ORF YBL009W 24.436 0.99 5 283.1913 1 YBL009W YBL009W SGDID:S000000105,haspin, Chr II from 207197-209227, Uncharacterized ORF YPR162C 28.58 0.72 9 316.9696 1 YPR162C ORC4 SGDID:S000006366,Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing, Chr XVI from 868300-866711, reverse complement, Verified ORF YFL013C 38.71 0.99 6 214.5201 1 YFL013C IES1 SGDID:S000001881,Subunit of the INO80 chromatin remodeling complex, Chr VI from 109924-107846, reverse complement, Verified ORF YEL026W 3.43 1.00 11 4483.3586 1 YEL026W SNU13 SGDID:S000000752,RNA binding protein, part of U3 snoRNP involved in rRNA processing, part of U4\U6-U5 tri-snRNP involved in mRNA splicing, similar to human 15.5K protein, Chr V from 101943-102323, Verified ORF YDR427W 24.98 1.00 4 223.8579 1 YDR427W RPN9 SGDID:S000002835,Non-ATPase regulatory subunit of the 26S proteasome, has similarity to putative proteasomal subunits in other species; null mutant is temperature sensitive and exhibits cell cycle and proteasome assembly defects, Chr IV from 1322197-1323378, Verified ORF YAL023C 21.92 1.00 13 829.1015 1 YAL023C PMT2 SGDID:S000000021,Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine\threonine residues; acts in a complex with Pmt1p, can instead interact with Pmt5p in some conditions; target for new antifungals, Chr I from 108552-106273, reverse complement, Verified ORF YAL025C 10.18 0.92 3 379.0235 1 YAL025C MAK16 SGDID:S000000023,Essential nuclear protein, constituent of 66S pre-ribosomal particles; required for normal concentration of free 60S ribosomal subunits; required for maintenance of M1 satellite double-stranded RNA of the L-A virus, Chr I from 101146-100226, reverse complement, Verified ORF YDL107W 18.379 0.88 1 66.9369 1 YDL107W MSS2 SGDID:S000002265,Peripherally bound inner membrane protein of the mitochondrial matrix, required for export of C-terminal tail of Cox2p through the inner membrane, Chr IV from 268921-269976, Verified ORF YDL024C 12.96 0.82 3 265.3597 1 YDL024C DIA3 SGDID:S000002182,Protein of unknown function, involved in invasive and pseudohyphal growth, Chr IV from 409854-408448, reverse complement, Verified ORF YNL163C 37.54 0.94 1 35.0056 1 YNL163C RIA1 SGDID:S000005107,Cytoplasmic GTPase involved in biogenesis of the 60S ribosome; has similarity to translation elongation factor 2 (Eft1p and Eft2p), Chr XIV from 330075-326743, reverse complement, Verified ORF YBR065C 19.878 0.84 6 354.4563 1 YBR065C ECM2 SGDID:S000000269,Pre-mRNA splicing factor, facilitates the cooperative formation of U2\U6 helix II in association with stem II in the spliceosome, function may be regulated by Slu7p, Chr II from 369676-368582, reverse complement, Verified ORF YOL148C 22.32 1.00 15 939.5112 1 YOL148C SPT20 SGDID:S000005508,Subunit of the SAGA transcriptional regulatory complex, involved in maintaining the integrity of the complex, Chr XV from 47573-45759, reverse complement, Verified ORF YJR069C 9.23 1.00 12 1817.542 1 YJR069C HAM1 SGDID:S000003830,Protein of unknown function that is involved in DNA repair; mutant is sensitive to the base analog, 6-N-hydroxylaminopurine, while gene disruption does not increase the rate of spontaneous mutagenesis, Chr X from 569314-568721, reverse complement, Verified ORF YGL157W 15.097 1.00 28 2592.8195 1 YGL157W YGL157W SGDID:S000003125,Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol), Chr VII from 209011-210054, Verified ORF YHR196W 25.568 1.00 6 328.0646 1 YHR196W UTP9 SGDID:S000001239,Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA, Chr VIII from 491931-493658, Verified ORF YNL061W 21.16 1.00 7 462.4739 1 YNL061W NOP2 SGDID:S000005005,Probable RNA m(5)C methyltransferase, essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; localized to the nucleolus; constituent of 66S pre-ribosomal particles, Chr XIV from 510541-512397, Verified ORF YDR309C 15.29 0.81 1 74.0597 1 YDR309C GIC2 SGDID:S000002717,Protein of unknown function involved in initiation of budding and cellular polarization, interacts with Cdc42p via the Cdc42\Rac-interactive binding (CRIB) domain, Chr IV from 1080195-1079044, reverse complement, Verified ORF YLR249W 45.069 1.00 1019 31608.3026 1 YLR249W YEF3 SGDID:S000004239,Translational elongation factor, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing EF-1 alpha from the ribosomal complex; contains two ABC cassettes; binds and hydrolyses ATP, Chr XII from 636782-639916, Verified ORF YOR046C 28.799 1.00 48 2330.0687 1 YOR046C DBP5 SGDID:S000005572,Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family involved in mRNA export from the nucleus, Chr XV from 415908-414460, reverse complement, Verified ORF YBR263W 20.09 1.00 100 6958.6497 1 YBR263W SHM1 SGDID:S000000467,Mitochondrial serine hydroxymethyltransferase, involved in one-carbon metabolism, Chr II from 736259-737731, Verified ORF YBL097W 31.3 0.90 3 120.5936 1 YBL097W BRN1 SGDID:S000000193,Essential protein required for chromosome condensation, likely to function as an intrinsic component of the condensation machinery, may influence multiple aspects of chromosome transmission and dynamics, Chr II from 40828-43092, Verified ORF YCR054C 25.86 0.99 2 107.0388 1 YCR054C CTR86 SGDID:S000000650,Essential protein of unknown function, Chr III from 220063-218372, reverse complement, Verified ORF YKL152C 16.612 1.00 638 53691.269 1 YKL152C GPM1 SGDID:S000001635,Tetrameric phosphoglycerate mutase, mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis, Chr XI from 164390-163647, reverse complement, Verified ORF YBL056W 13.29 0.88 1 92.5683 1 YBL056W PTC3 SGDID:S000000152,Type 2C protein phosphatase; dephosphorylates Hog1p (see also Ptc2p) to limit maximal kinase activity induced by osmotic stress; dephosphorylates T169 phosphorylated Cdc28p (see also Ptc2p); role in DNA checkpoint inactivation, Chr II from 113765-115171, Verified ORF YER089C 16.83 1.00 32 2658.0966 1 YER089C PTC2 SGDID:S000000891,Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress induced kinase activity; dephosphorylates Ire1p to downregulate the unfolded protein response; dephosphorylates Cdc28p; role in DNA checkpoint inactivation, Chr V from 337336-335942, reverse complement, Verified ORF YMR076C 62.7 0.93 10 207.3577 1 YMR076C PDS5 SGDID:S000004681,Protein required for establishment and maintenance of sister chromatid condensation and cohesion, colocalizes with cohesin on chromosomes in an interdependent manner, may function as a protein-protein interaction scaffold, Chr XIII from 420028-416195, reverse complement, Verified ORF YOR251C 19.619 0.78 2 111.161 1 YOR251C YOR251C SGDID:S000005777,catalyzes transfer of the sulfane atom of thiosulfate to cyanide to form sulfite and thiocyanate, Chr XV from 803465-802551, reverse complement, Uncharacterized ORF YNL236W 41.687 0.98 6 197.1885 1 YNL236W SIN4 SGDID:S000005180,Subunit of the Mediator complex; interacts with the RNA polymerase II holoenzyme to postively or negatively regulate transcription; dispensible for basal transcription, Chr XIV from 206931-209855, Verified ORF YOR336W 53.29 0.99 3 77.914 1 YOR336W KRE5 SGDID:S000005863,Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects, Chr XV from 949770-953867, Verified ORF YEL003W 5.052 1.00 18 4980.9717 1 YEL003W GIM4 SGDID:S000000729,Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it, Chr V from 148227-148598, Verified ORF YGR132C 12.599 1.00 16 1775.3697 1 YGR132C PHB1 SGDID:S000003364,Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation, Chr VII from 756457-755594, reverse complement, Verified ORF YLR410W 55.809 1.00 9 225.4463 1 YLR410W VIP1 SGDID:S000004402,Protein of unknown function probably involved in the function of the cortical actin cytoskeleton; putative ortholog of S. pombe asp1+, Chr XII from 937539-940979, Verified ORF YKR019C 18.76 0.88 2 131.1549 1 YKR019C IRS4 SGDID:S000001727,Protein involved in regulation of phosphatidylinositol 4,5-bisphosphate concentrations; Irs4p and Tax4p bind and activate the phosphatase Inp51p; mutation confers an increase in rDNA silencing, Chr XI from 477706-475859, reverse complement, Verified ORF YBR101C 17.55 1.00 13 1035.5501 1 YBR101C FES1 SGDID:S000000305,Hsp70 (Ssa1p) nucleotide exchange factor, cytosolic homolog of Sil1p, which is the nucleotide exchange factor for BiP (Kar2p) in the endoplasmic reticulum, Chr II from 444687-443815, reverse complement, Verified ORF YHR007C 20.139 1.00 51 3540.2765 1 YHR007C ERG11 SGDID:S000001049,Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family, Chr VIII from 121678-120086, reverse complement, Verified ORF YNL139C 62.678 1.00 16 356.8697 1 YNL139C RLR1 SGDID:S000005083,Subunit of the THO complex, which is required for efficient transcription elongation and involved in transcriptional elongation-associated recombination; required for LacZ RNA expression from certain plasmids, Chr XIV from 365719-360926, reverse complement, Verified ORF YDR083W 18.558 1.00 40 3013.24 1 YDR083W RRP8 SGDID:S000002490,Nucleolar protein involved in rRNA processing, pre-rRNA cleavage at site A2; also involved in telomere maintenance; mutation is synthetically lethal with a gar1 mutation, Chr IV from 612070-613248, Verified ORF YFR009W 35.825 1.00 30 1170.6847 1 YFR009W GCN20 SGDID:S000001905,Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p; proposed to stimulate Gcn2p activation by an uncharged tRNA, Chr VI from 162482-164740, Verified ORF YNL313C 38.37 1.00 7 255.0416 1 YNL313C YNL313C SGDID:S000005257,Protein required for cell viability, Chr XIV from 48021-45307, reverse complement, Uncharacterized ORF YCR051W 10.95 1.00 22 2808.7525 1 YCR051W YCR051W SGDID:S000000647,Hypothetical protein, Chr III from 214067-214735, Uncharacterized ORF YOR267C 19.51 1.00 6 429.9311 1 YOR267C HRK1 SGDID:S000005793,Protein kinase implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis, Chr XV from 824866-822587, reverse complement, Verified ORF YLR109W 7.24 1.00 140 27033.0085 1 YLR109W AHP1 SGDID:S000004099,Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p, Chr XII from 368782-369312, Verified ORF YFR038W 36.83 1.00 4 151.8319 1 YFR038W YFR038W SGDID:S000001934,Putative ATPase containing the DEAD\H helicase-related sequence motif; YFR038W is not an essential gene, Chr VI from 229367-231928, Uncharacterized ORF YKL009W 10.42 1.00 19 2549.123 1 YKL009W MRT4 SGDID:S000001492,Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus, Chr XI from 425885-426595, Verified ORF YOR091W 16.218 1.00 14 1206.8009 1 YOR091W YOR091W SGDID:S000005617,Hypothetical protein, Chr XV from 493434-494471, Uncharacterized ORF YJR121W 26.69 1.00 341 17861.2034 1 YJR121W ATP2 SGDID:S000003882,Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis, Chr X from 647523-649058, Verified ORF YOL004W 49.178 0.98 1 27.8586 1 YOL004W SIN3 SGDID:S000005364,DNA binding subunit of Sin3p-Rpd3p histone deacetylase complex, involved in transcriptional repression of meiosis-specific genes during vegetative growth and silencing; involved in telomere maintenance, Chr XV from 316939-321549, Verified ORF YKR059W 19.09 1.00 511 37421.3873 2 YKR059W,YJL138C TIF1 SGDID:S000001767,Translation initiation factor eIF4A, identical to Tif2p; DEA(D\H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G, Chr XI from 554629-555816, Verified ORF YOR063W 17.795 1.00 386 30324.5402 1 YOR063W RPL3 SGDID:S000005589,Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus, Chr XV from 444688-445851, Verified ORF YAR015W 23.855 1.00 59 3457.6219 1 YAR015W ADE1 SGDID:S000000070,N-succinyl-5-aminoimidazole-4-carboxamide ribotide (SAICAR) synthetase, required for 'de novo' purine nucleotide biosynthesis; red pigment accumulates in mutant cells deprived of adenine, Chr I from 169370-170290, Verified ORF YJR060W 13.65 0.99 10 1013.9287 1 YJR060W CBF1 SGDID:S000003821,Helix-loop-helix protein that binds the motif CACRTG, which is present at several sites including MET gene promoters and centromere DNA element I (CDEI); required for nucleosome positioning at this motif; targets Isw1p to DNA, Chr X from 548674-549729, Verified ORF YBR205W 19.76 0.71 4 200.926 1 YBR205W KTR3 SGDID:S000000409,Putative alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; member of the KRE2\MNT1 mannosyltransferase family, Chr II from 633617-634831, Verified ORF YHR072W-A 2.39 1.00 12 7019.2103 1 YHR072W-A NOP10 SGDID:S000007455,Constituent of small nucleolar ribonucleoprotein particles containing H\ACA-type snoRNAs, which are required for pseudouridylation and processing of pre-18S rRNA, Chr VIII from 241666-241842, Verified ORF YIL017C 34.83 0.87 2 69.8394 1 YIL017C VID28 SGDID:S000001279,Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); localized to the nucleus and the cytoplasm, Chr IX from 320963-318198, reverse complement, Verified ORF YML110C 13.17 1.00 10 1061.4978 1 YML110C COQ5 SGDID:S000004578,2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase, involved in ubiquinone (Coenzyme Q) biosynthesis; located in mitochondria, Chr XIII from 50954-50031, reverse complement, Verified ORF YIL124W 10.9 0.95 5 609.217 1 YIL124W AYR1 SGDID:S000001386,NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles, ER, and mitochondrial outer membrane; involved in phosphatidic acid biosynthesis; required for spore germination; capable of metabolizing steroid hormones, Chr IX from 126204-127097, Verified ORF YLR305C 61.987 1.00 19 428.5069 1 YLR305C STT4 SGDID:S000004296,Phosphatidylinositol-4-kinase that functions in the Pkc1p protein kinase pathway; required for normal vacuole morphology, cell wall integrity, and actin cytoskeleton organization, Chr XII from 743865-738163, reverse complement, Verified ORF YLR216C 14.32 1.00 36 3514.5068 1 YLR216C CPR6 SGDID:S000004206,Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity, Chr XII from 573213-572098, reverse complement, Verified ORF YNL132W 49.035 1.00 37 1054.8736 1 YNL132W KRE33 SGDID:S000005076,Essential protein of unknown function; heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance, Chr XIV from 375323-378493, Verified ORF YMR134W 10.19 0.91 16 1997.5244 1 YMR134W YMR134W SGDID:S000004741,Protein required for cell viability, Chr XIII from 537837-538550, Uncharacterized ORF YNL149C 7.81 1.00 5 895.0017 1 YNL149C YNL149C SGDID:S000005093,Essential protein required for maturation of Gas1p and Pho8p; GFP-fusion protein localizes to the endoplasmic reticulum (ER) and YFP-fusion protein to the nuclear envelope-ER network; null mutants have a cell separation defect, Chr XIV from 349758-349369, reverse complement, Uncharacterized ORF YGR234W 15.851 1.00 168 14816.906 1 YGR234W YHB1 SGDID:S000003466,Nitric oxide oxidoreductase, flavohemoglobin involved in nitric oxide detoxification; plays a role in the oxidative and nitrosative stress responses, Chr VII from 959908-961107, Verified ORF YJL092W 56.589 0.97 11 263.595 1 YJL092W HPR5 SGDID:S000003628,DNA helicase and DNA-dependent ATPase involved in DNA repair, required for proper timing of commitment to meiotic recombination and the transition from Meiosis I to Meiosis II; potential Cdc28p substrate, Chr X from 257340-260864, Verified ORF YDR158W 12.31 1.00 34 3861.2309 1 YDR158W HOM2 SGDID:S000002565,Aspartic beta semi-aldehyde dehydrogenase, catalyzes the second step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis, Chr IV from 770354-771451, Verified ORF YCR004C 9.989 1.00 24 3358.8773 1 YCR004C YCP4 SGDID:S000000597,Protein of unknown function, has sequence and structural similarity to flavodoxins; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern, Chr III from 120316-119573, reverse complement, Verified ORF YCR057C 40.63 0.86 4 118.3631 1 YCR057C PWP2 SGDID:S000000653,Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis, Chr III from 223224-220453, reverse complement, Verified ORF YDR096W 27.52 1.00 7 355.594 1 YDR096W GIS1 SGDID:S000002503,Transcriptional factor, involved in the expression of genes during nutrient limitation; also involved in the negative regulation of DPP1 and PHR1, Chr IV from 637136-639820, Verified ORF YML022W 8.678 1.00 25 4027.4047 1 YML022W APT1 SGDID:S000004484,Adenine phosphoribosyltransferase, catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis, Chr XIII from 228937-229500, Verified ORF YLR086W 68.34 0.96 4 78.5527 1 YLR086W SMC4 SGDID:S000004076,Subunit of the condensin complex, which reorganizes chromosomes during cell division, forms a stable complex with Smc2p that has ATP-hydrolyzing and DNA-binding activity and promotes knotting of circular DNA; potential Cdc28p substrate, Chr XII from 302244-306500, Verified ORF YPR173C 20.796 1.00 15 1008.3617 1 YPR173C VPS4 SGDID:S000006377,AAA-type ATPase required for efficient late endosome to vacuole transport; catalyzes the release of an endosomal membrane-associated class E VPS protein complex; cytoplasmic protein that is also associated with an endosomal compartment, Chr XVI from 887833-886520, reverse complement, Verified ORF YDR356W 53.73 0.87 8 181.0911 1 YDR356W SPC110 SGDID:S000002764,Inner plaque spindle pole body (SPB) component, ortholog of human kendrin; involved in connecting nuclear microtubules to SPB; interacts with Tub4p-complex and calmodulin; phosphorylated by Mps1p in cell cycle-dependent manner, Chr IV from 1186100-1188934, Verified ORF YOR369C 8.32 1.00 229 38478.4056 1 YOR369C RPS12 SGDID:S000005896,Protein component of the small (40S) ribosomal subunit; has similarity to rat ribosomal protein S12, Chr XV from 1028623-1028192, reverse complement, Verified ORF YPR137W 24.32 1.00 9 517.3492 1 YPR137W RRP9 SGDID:S000006341,Protein involved in pre-rRNA processing, associated with U3 snRNP; component of small ribosomal subunit (SSU) processosome; ortholog of the human U3-55k protein, Chr XVI from 802355-804076, Verified ORF YAL011W 22.79 0.65 1 39.8725 1 YAL011W SWC3 SGDID:S000000009,Protein of unknown function, component of the Swr1p complex that incorporates Htz1p into chromatin; required for formation of nuclear-associated array of smooth endoplasmic reticulum known as karmellae, Chr I from 132202-134079, Verified ORF YMR021C 11.255 0.83 10 1030.9497 1 YMR021C MAC1 SGDID:S000004623,Copper-sensing transcription factor involved in regulation of genes required for high affinity copper transport, Chr XIII from 318417-317164, reverse complement, Verified ORF YHR039C-A 5.79 1.00 19 4587.5409 1 YHR039C-A VMA10 SGDID:S000002100,Vacuolar H+ ATPase subunit G of the catalytic (V1) sector, involved in vacuolar acidification, Chr VIII from 187672-187670,187507-187166, reverse complement, Verified ORF YJR014W 6.424 0.99 25 5386.1021 1 YJR014W YJR014W SGDID:S000003775,Hypothetical protein, Chr X from 461744-462340, Uncharacterized ORF YJR145C 13.538 1.00 176 18174.525 2 YHR203C,YJR145C RPS4A SGDID:S000003906,Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein, Chr X from 702984-702971,702714-701943, reverse complement, Verified ORF YBL034C 70.976 1.00 11 216.6636 1 YBL034C STU1 SGDID:S000000130,Component of the mitotic spindle that binds to interpolar microtubules via its association with beta-tubulin (Tub2p); required for interpolar microtubules to provide an outward force on the spindle poles, Chr II from 158392-153851, reverse complement, Verified ORF YNL067W 8.08 1.00 174 30105.2889 1 YNL067W RPL9B SGDID:S000005011,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Ap and has similarity to E. coli L6 and rat L9 ribosomal proteins, Chr XIV from 499682-500257, Verified ORF YPL060W 18.53 0.93 4 280.6547 1 YPL060W LPE10 SGDID:S000005981,Mitochondrial inner membrane magnesium transporter, involved in maintenance of magnesium concentrations inside mitochondria; indirectly affects splicing of group II introns; functionally and structurally related to Mrs2p, Chr XVI from 434520-435761, Verified ORF YER087W 30.168 0.94 1 43.5598 1 YER087W YER087W SGDID:S000000889,Hypothetical protein, Chr V from 330572-332302, Uncharacterized ORF YHL009W-B 83.1099999999999 1.00 28 470.9878 2 YJL113W,YHL009W-B YHL009W-B SGDID:S000007372,TyB Gag-Pol protein; proteolytically processed to make the Gag, RT, PR, and IN proteins that are required for retrotransposition, Chr VIII from 85905-86990,86992-91314, transposable_element_gene YNL092W 11.06 0.70 3 265.4416 1 YNL092W YNL092W SGDID:S000005036,Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family, Chr XIV from 450873-452075, Uncharacterized ORF YJR110W 24.588 0.83 3 141.5732 1 YJR110W YMR1 SGDID:S000003871,Phosphatidylinositol 3-phosphate [PI(3)P] phosphatase, regulates the localization and levels of PI(3)P; involved in cytoplasm to vacuole (CVT) transport; has similarity to the conserved myotubularin dual specificity phosphatase family, Chr X from 633531-635597, Verified ORF YKL033W 39.128 0.88 2 62.8825 1 YKL033W YKL033W SGDID:S000001516,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YKL033W is an essential gene, Chr XI from 375099-378215, Uncharacterized ORF YNL106C 47.24 0.99 7 205.0823 1 YNL106C INP52 SGDID:S000005050,Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in endocytosis; hyperosmotic stress causes translocation to actin patches, Chr XIV from 424497-420946, reverse complement, Verified ORF YBR025C 17.32 1.00 163 13156.629 1 YBR025C YBR025C SGDID:S000000229,Hypothetical protein, Chr II from 291865-290681, reverse complement, Uncharacterized ORF YKL150W 16.62 1.00 15 1261.7262 1 YKL150W MCR1 SGDID:S000001633,Mitochondrial NADH-cytochrome b5 reductase, involved in ergosterol biosynthesis, Chr XI from 166549-167457, Verified ORF YOR332W 16.78 1.00 113 9414.3729 1 YOR332W VMA4 SGDID:S000005859,Subunit E of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane, Chr XV from 943653-944354, Verified ORF YNL208W 5.13 1.00 11 2997.6452 1 YNL208W YNL208W SGDID:S000005152,Hypothetical protein, Chr XIV from 254419-255018, Uncharacterized ORF YER055C 12.66 1.00 79 8723.6513 1 YER055C HIS1 SGDID:S000000857,ATP phosphoribosyltransferase, a hexameric enzyme, catalyzes the first step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control, Chr V from 265784-264891, reverse complement, Verified ORF YJR123W 7.84 1.00 357 63658.5974 1 YJR123W RPS5 SGDID:S000003884,Protein component of the small (40S) ribosomal subunit, the least basic of the non-acidic ribosomal proteins; phosphorylated in vivo; essential for viability; has similarity to E. coli S7 and rat S5 ribosomal proteins, Chr X from 651817-652494, Verified ORF YMR318C 15.815 1.00 42 3712.6585 1 YMR318C ADH6 SGDID:S000004937,NADPH-dependent cinnamyl alcohol dehydrogenase family member with broad substrate specificity; may be involved in fusel alcohol synthesis or in aldehyde tolerance, Chr XIII from 912141-911059, reverse complement, Verified ORF YGL078C 22.176 1.00 21 1323.8567 1 YGL078C DBP3 SGDID:S000003046,Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis, Chr VII from 361862-360291, reverse complement, Verified ORF YKL104C 30.14 1.00 46 2133.6319 1 YKL104C GFA1 SGDID:S000001587,Glutamine-fructose-6-phosphate amidotransferase, catalyzes the formation of glucosamine-6-P and glutamate from fructose-6-P and glutamine in the first step of chitin biosynthesis, Chr XI from 245017-242864, reverse complement, Verified ORF YDR086C 3.87 1.00 19 6863.5301 1 YDR086C SSS1 SGDID:S000002493,Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) that forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p, Chr IV from 617167-616925, reverse complement, Verified ORF YJR094W-A 2.96 1.00 134 63287.5086 2 YPR043W,YJR094W-A RPL43B SGDID:S000003855,Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein, Chr X from 608223-608224,608500-608776, Verified ORF YKL172W 18.17 1.00 8 615.5168 1 YKL172W EBP2 SGDID:S000001655,Essential protein required for the maturation of 25S rRNA and 60S ribosomal subunit assembly, localizes to the nucleolus; constituent of 66S pre-ribosomal particles, Chr XI from 125764-127047, Verified ORF YDR293C 53.139 1.00 7 184.1575 1 YDR293C SSD1 SGDID:S000002701,Protein with a role in maintenance of cellular integrity, interacts with components of the TOR pathway; ssd1 mutant of a clinical S. cerevisiae strain displays elevated virulence, Chr IV from 1049388-1045636, reverse complement, Verified ORF YNL099C 9 0.95 1 147.5658 1 YNL099C OCA1 SGDID:S000005043,Putative protein tyrosine phosphatase, required for cell cycle arrest in response to oxidative damage of DNA, Chr XIV from 439285-438569, reverse complement, Verified ORF YKL201C 47.82 0.99 9 260.4791 1 YKL201C MNN4 SGDID:S000001684,Putative positive regulator of mannosylphosphate transferase (Mnn6p), involved in mannosylphosphorylation of N-linked oligosaccharides; expression increases in late-logarithmic and stationary growth phases, Chr XI from 67467-63931, reverse complement, Verified ORF YJL128C 21.97 1.00 10 636.3189 1 YJL128C PBS2 SGDID:S000003664,MAP kinase kinase that plays a pivotal role in the osmosensing signal-transduction pathway, activated under severe osmotic stress, Chr X from 180022-178016, reverse complement, Verified ORF YFL047W 27.35 0.74 16 605.2005 1 YFL047W RGD2 SGDID:S000001847,GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p, Chr VI from 40421-42565, Verified ORF YJR002W 23.27 1.00 11 660.8474 1 YJR002W MPP10 SGDID:S000003762,Component of the SSU processome, which is required for pre-18S rRNA processing, interacts with and controls the stability of Imp3p and Imp4p, essential for viability; similar to human Mpp10p, Chr X from 438780-440561, Verified ORF YKL006W 6.74 1.00 215 44594.7235 2 YHL001W,YKL006W RPL14A SGDID:S000001489,N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl14Bp and has similarity to rat L14 ribosomal protein; rpl14a csh5 double null mutant exhibits synthetic slow growth, Chr XI from 431549-431677,432076-432363, Verified ORF YHR102W 26.68 0.79 10 413.9483 1 YHR102W KIC1 SGDID:S000001144,Protein kinase of the PAK\Ste20 kinase family, required for cell integrity possibly through regulating 1,6-beta-glucan levels in the wall; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body, Chr VIII from 316575-319817, Verified ORF YCL057W 40.23 1.00 7 243.25 1 YCL057W PRD1 SGDID:S000000562,Zinc metalloendopeptidase, found in the cytoplasm and intermembrane space of mitochondria; with Cym1p, involved in degradation of mitochondrial proteins and of presequence peptides cleaved from imported proteins, Chr III from 24768-26906, Verified ORF YKL067W 9.62 1.00 21 3051.7512 1 YKL067W YNK1 SGDID:S000001550,Nucleoside diphosphate kinase, catalyzes the transfer of gamma phosphates from nucleoside triphosphates, usually ATP, to nucleoside diphosphates by a mechanism that involves formation of an autophosphorylated enzyme intermediate, Chr XI from 314456-314917, Verified ORF YDR117C 25.506 0.70 6 230.2034 1 YDR117C YDR117C SGDID:S000002524,Hypothetical protein, Chr IV from 685640-683943, reverse complement, Uncharacterized ORF YJL157C 33.01 0.99 5 209.6353 1 YJL157C FAR1 SGDID:S000003693,Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to pheromone; also forms a complex with Cdc24p, Ste4p, and Ste18p that may specify the direction of polarized growth during mating; potential Cdc28p substrate, Chr X from 126246-123754, reverse complement, Verified ORF YDR097C 63.9 0.98 13 278.7234 1 YDR097C MSH6 SGDID:S000002504,Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair both single-base + insertion-deletion mispairs; potentially phosphorylated by Cdc28p, Chr IV from 643834-640106, reverse complement, Verified ORF YER120W 10.88 1.00 55 7067.0588 1 YER120W SCS2 SGDID:S000000922,Integral ER membrane protein that regulates phospholipid metabolism via an interaction with the FFAT motif of Opi1p, also involved in telomeric silencing, disruption causes inositol auxotrophy above 34 degrees C, VAP homolog, Chr V from 401131-401865, Verified ORF YGL216W 21.58 0.79 18 921.1981 1 YGL216W KIP3 SGDID:S000003184,Kinesin-related motor protein involved in mitotic spindle positioning , Chr VII from 84884-87301, Verified ORF YDR002W 8.14 1.00 63 10819.8454 1 YDR002W YRB1 SGDID:S000002409,Ran GTpase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1, Chr IV from 453042-453647, Verified ORF YGL207W 46.389 1.00 30 904.0889 1 YGL207W SPT16 SGDID:S000003175,Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure, Chr VII from 98973-102080, Verified ORF YJL066C 14.05 1.00 2 199.0025 1 YJL066C MPM1 SGDID:S000003602,Mitochondrial membrane protein of unknown function, contains no hydrophobic stretches, Chr X from 314789-314031, reverse complement, Verified ORF YPL106C 35.074 1.00 520 20726.3562 1 YPL106C SSE1 SGDID:S000006027,ATPase that is a component of the heat shock protein Hsp90 chaperone complex; binds unfolded proteins; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm, Chr XVI from 352272-350191, reverse complement, Verified ORF YLR256W 45.96 0.90 8 219.0066 1 YLR256W HAP1 SGDID:S000004246,Zinc finger transcription factor involved in the complex regulation of gene expression in response to levels of heme and oxygen; the S288C sequence differs from other strain backgrounds due to a Ty1 insertion in the carboxy terminus, Chr XII from 646417-650925, Verified ORF YER006W 27.733 1.00 54 2722.0858 1 YER006W NUG1 SGDID:S000000808,GTPase that associates with nuclear 60S pre-ribosomes, required for export of 60S ribosomal subunits from the nucleus, Chr V from 162722-164284, Verified ORF YPR191W 26.37 1.00 40 2120.5805 1 YPR191W QCR2 SGDID:S000006395,Subunit 2 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; transcription is regulated by Hap1p, Hap2p\Hap3p, and heme, Chr XVI from 919377-920483, Verified ORF YIR037W 9.065 0.94 1 144.9656 1 YIR037W HYR1 SGDID:S000001476,Thiol peroxidase that functions as a hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce a redox signal to the Yap1p transcription factor, Chr IX from 423125-423616, Verified ORF YMR241W 11.5 1.00 32 3890.0667 1 YMR241W YHM2 SGDID:S000004854,Mitochondrial DNA-binding protein, component of the mitochondrial nucleoid structure, involved in mtDNA replication and segregation of mitochondrial genomes; member of the mitochondrial carrier protein family, Chr XIII from 751960-752904, Verified ORF YJL189W 0.69 1.00 49 99277.7445 1 YJL189W RPL39 SGDID:S000003725,Protein component of the large (60S) ribosomal subunit, has similarity to rat L39 ribosomal protein; required for ribosome biogenesis; exhibits genetic interactions with SIS1 and PAB1, Chr X from 75932-75937,76324-76473, Verified ORF YER132C 69.55 0.99 12 238.7944 1 YER132C PMD1 SGDID:S000000934,Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expression; required, with Mds3p, for growth under alkaline conditions, Chr V from 430445-425184, reverse complement, Verified ORF YJL008C 30.36 1.00 47 2164.2179 1 YJL008C CCT8 SGDID:S000003545,Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo, Chr X from 421579-419873, reverse complement, Verified ORF YBR260C 25.978 0.99 3 159.829 1 YBR260C RGD1 SGDID:S000000464,GTPase-activating protein (RhoGAP) for Rho3p and Rho4p, possibly involved in control of actin cytoskeleton organization, Chr II from 734634-732634, reverse complement, Verified ORF YBR115C 63.14 1.00 22 487.1054 1 YBR115C LYS2 SGDID:S000000319,Alpha aminoadipate reductase, catalyzes the reduction of alpha-aminoadipate to alpha-aminoadipate 6-semialdehyde, which is the fifth step in biosynthesis of lysine; activation requires posttranslational phosphopantetheinylation by Lys5p, Chr II from 473920-469742, reverse complement, Verified ORF YJR041C 47.288 1.00 6 177.3802 1 YJR041C URB2 SGDID:S000003802,Nucleolar protein required for normal metabolism of the rRNA primary transcript, proposed to be involved in ribosome biogenesis, Chr X from 513678-510154, reverse complement, Verified ORF YFL003C 39.107 0.99 7 247.7328 1 YFL003C MSH4 SGDID:S000001891,Protein involved in meiotic recombination, required for normal levels of crossing over, colocalizes with Zip2p to discrete foci on meiotic chromosomes, has homology to bacterial MutS protein, Chr VI from 137152-134516, reverse complement, Verified ORF YGL056C 16.06 1.00 4 348.1924 1 YGL056C SDS23 SGDID:S000003024,One of two S. cerevisiae homologs (Sds23p and Sds24p) of the Schizosaccharomyces pombe Sds23 protein, which genetic studies have implicated in APC\cyclosome regulation, Chr VII from 397624-396041, reverse complement, Verified ORF YOL120C 7.81 1.00 45 8055.0157 2 YOL120C,YNL301C RPL18A SGDID:S000005480,Protein component of the large (60S) ribosomal subunit, identical to Rpl18Bp and has similarity to rat L18 ribosomal protein; intron of RPL18A pre-mRNA forms stem-loop structures that are a target for Rnt1p cleavage leading to degradation, Chr XV from 94402-94291,93843-93395, reverse complement, Verified ORF YPR029C 34.489 1.00 22 891.7579 1 YPR029C APL4 SGDID:S000006233,Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport, Chr XVI from 626964-624466, reverse complement, Verified ORF YLR065C 4.58 0.98 1 299.1338 1 YLR065C YLR065C SGDID:S000004055,Putative protein of unknown function; YLR065C is not an essential gene, Chr XII from 266919-266374, reverse complement, Uncharacterized ORF YPL134C 12.68 0.78 1 85.9963 1 YPL134C ODC1 SGDID:S000006055,Mitochondrial inner membrane transporter, exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for use in lysine and glutamate biosynthesis and in lysine catabolism, Chr XVI from 299502-298570, reverse complement, Verified ORF YDR011W 45.37 1.00 6 184.8789 1 YDR011W SNQ2 SGDID:S000002418,ABC transporter protein involved in multidrug resistance and resistance to singlet oxygen species, Chr IV from 465916-470421, Verified ORF YHR165C 95.9370000000001 0.99 7 100.9838 1 YHR165C PRP8 SGDID:S000001208,Component of the U4\U6-U5 snRNP complex, involved in the second catalytic step of splicing, Chr VIII from 436950-429709, reverse complement, Verified ORF YER078C 17.666 0.99 7 548.4031 1 YER078C YER078C SGDID:S000000880,Metallopeptidase, localized to the mitochondrial matrix, Chr V from 318338-316803, reverse complement, Uncharacterized ORF YPL270W 32.64 0.88 10 376.9098 1 YPL270W MDL2 SGDID:S000006191,Half-type ATP-binding cassette (ABC) transporter of the inner mitochondrial membrane, Chr XVI from 30482-32803, Verified ORF YNL062C 15.078 0.96 3 267.026 1 YNL062C GCD10 SGDID:S000005006,Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p, required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression, Chr XIV from 510213-508777, reverse complement, Verified ORF YLR129W 46.192 0.74 1 22.3959 1 YLR129W DIP2 SGDID:S000004119,Nucleolar protein, specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex, Chr XII from 399658-402489, Verified ORF YML001W 10.706 1.00 12 1566.9636 1 YML001W YPT7 SGDID:S000004460,GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion, similar to mammalian Rab7, Chr XIII from 267174-267800, Verified ORF YKL185W 21.64 0.88 3 170.5499 1 YKL185W ASH1 SGDID:S000001668,Zinc-finger inhibitor of HO transcription; mRNA is localized and translated in the distal tip of anaphase cells, resulting in accumulation of Ash1p in daughter cell nuclei and inhibition of HO expression; potential Cdc28p substrate, Chr XI from 94504-96270, Verified ORF YOR272W 16.87 0.91 2 150.8207 1 YOR272W YTM1 SGDID:S000005798,Constituent of 66S pre-ribosomal particles, required for maturation of the large ribosomal subunit, Chr XV from 832812-834194, Verified ORF YML106W 12.75 1.00 36 3947.2735 1 YML106W URA5 SGDID:S000004574,One of two orotate phosphoribosyltransferase isozymes (see also URA10) that catalyze the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate, Chr XIII from 56773-57453, Verified ORF YOL040C 3.93 1.00 116 41263.9075 1 YOL040C RPS15 SGDID:S000005400,Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S19 and rat S15 ribosomal proteins, Chr XV from 253576-253148, reverse complement, Verified ORF YBR078W 7.89 0.99 12 2104.9624 1 YBR078W ECM33 SGDID:S000000282,GPI-anchored protein of unknown function, has a possible role in apical bud growth; GPI-anchoring on the plasma membrane crucial to function; similar to Sps2p and Pst1p, Chr II from 393118-393175,393506-394854, Verified ORF YOR261C 17.3 1.00 36 2909.1178 1 YOR261C RPN8 SGDID:S000005787,Essential, non-ATPase regulatory subunit of the 26S proteasome; has similarity to the human p40 proteasomal subunit and to another S. cerevisiae regulatory subunit, Rpn11p, Chr XV from 816931-815915, reverse complement, Verified ORF YHR012W 9.99 0.94 1 131.5428 1 YHR012W VPS29 SGDID:S000001054,Endosomal protein that is a subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde transport; forms a subcomplex with Vps35p and Vps26p that selects cargo proteins for endosome-to-Golgi retrieval, Chr VIII from 129475-129522,129642-130442, Verified ORF YDR261C 24.98 0.96 17 913.3403 1 YDR261C EXG2 SGDID:S000002669,Exo-1,3-beta-glucanase, involved in cell wall beta-glucan assembly; may be anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor, Chr IV from 979205-977517, reverse complement, Verified ORF YLR367W 7.98 1.00 185 32409.6058 2 YJL190C,YLR367W RPS22B SGDID:S000004359,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Ap and has similarity to E. coli S8 and rat S15a ribosomal proteins, Chr XII from 856441-856573,857057-857316, Verified ORF YDL046W 4.11 0.91 1 309.5312 1 YDL046W NPC2 SGDID:S000002204,Functional homolog of human NPC2\He1, which is a cholesterol-binding protein whose deficiency causes Niemann-Pick type C2 disease involving retention of cholesterol in lysosomes, Chr IV from 371237-371758, Verified ORF YER125W 35.6 1.00 16 628.3113 1 YER125W RSP5 SGDID:S000000927,Ubiquitin-protein ligase involved in ubiquitin-mediated protein degradation; plays a role in heat shock element (HSE)-mediated gene expression and multivesicular body sorting; contains a hect (homologous to E6-AP carboxyl terminus) domain, Chr V from 410185-412614, Verified ORF YCL061C 49.33 0.92 4 104.2897 1 YCL061C MRC1 SGDID:S000000566,S-phase checkpoint protein found at replication forks, required for DNA replication; also required for Rad53p activation during DNA replication stress, where it forms a replication-pausing complex with Tof1p and is phosphorylated by Mec1p; protein involved in replication checkpoint, Chr III from 22106-18816, reverse complement, Verified ORF YFL022C 22.749 1.00 134 8234.6927 1 YFL022C FRS2 SGDID:S000001872,Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar, Chr VI from 95008-93497, reverse complement, Verified ORF YDR517W 9.9 0.95 1 134.1508 1 YDR517W GRH1 SGDID:S000002925,Protein involved in the spindle assembly checkpoint; homolog of human GRASP65, which is a Golgi localized protein that functions in postmitotic reassembly of Golgi stacks, Chr IV from 1477231-1478349, Uncharacterized ORF YAL001C 60.235 1.00 5 116.0448 1 YAL001C TFC3 SGDID:S000000001,Largest of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauB domain of TFIIIC that binds DNA at the BoxB promoter sites of tRNA and similar genes; cooperates with Tfc6p in DNA binding, Chr I from 151168-151099,151008-147596, reverse complement, Verified ORF YIL033C 22.29 1.00 9 564.4654 1 YIL033C BCY1 SGDID:S000001295,Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA), a component of a signaling pathway that controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation, Chr IX from 291668-290418, reverse complement, Verified ORF YLL018C 27.28 1.00 210 10761.6742 1 YLL018C DPS1 SGDID:S000003941,Cytoplasmic aspartyl-tRNA synthetase, homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp); class II aminoacyl tRNA synthetase; binding to its own mRNA may confer autoregulation, Chr XII from 111574-109901, reverse complement, Verified ORF YIL001W 20.875 0.96 11 707.2001 1 YIL001W YIL001W SGDID:S000001263,Hypothetical protein, Chr IX from 353937-355478, Uncharacterized ORF YJR132W 29.36 1.00 10 476.1555 1 YJR132W NMD5 SGDID:S000003893,Karyopherin, a carrier protein involved in nuclear import of proteins; importin beta homolog, Chr X from 669438-672584, Verified ORF YKL127W 25.254 1.00 15 830.3591 1 YKL127W PGM1 SGDID:S000001610,Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism, Chr XI from 203185-204897, Verified ORF YJR147W 10.41 0.82 1 110.1204 1 YJR147W HMS2 SGDID:S000003908,Protein with similarity to heat shock transcription factors; overexpression suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant, Chr X from 704112-705188, Verified ORF YER021W 22.678 1.00 13 801.3892 1 YER021W RPN3 SGDID:S000000823,Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to the p58 subunit of the human 26S proteasome; temperature-sensitive alleles cause metaphase arrest, suggesting a role for the proteasome in cell cycle control, Chr V from 196947-198518, Verified ORF YDR382W 9.17 1.00 276 42076.9894 1 YDR382W RPP2B SGDID:S000002790,Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm, Chr IV from 1239484-1239816, Verified ORF YKL014C 82.289 1.00 9 152.8993 1 YKL014C URB1 SGDID:S000001497,Nucleolar protein required for the normal accumulation of 25S and 5.8S rRNAs, associated with the 27SA2 pre-ribosomal particle; proposed to be involved in the biogenesis of the 60S ribosomal subunit, Chr XI from 416556-411262, reverse complement, Verified ORF YML014W 11.14 0.96 13 1566.1534 1 YML014W TRM9 SGDID:S000004476,tRNA methyltransferase, catalyzes the esterification of modified uridine nucleotides in tRNAs, creating 5-methylcarbonylmethyluridine in tRNA(Arg3) and 5-methylcarbonylmethyl-2-thiouridine in tRNA(Glu); may have a role in stress response, Chr XIII from 243225-244064, Verified ORF YNL102W 65.528 0.99 7 147.8465 1 YNL102W POL1 SGDID:S000005046,Catalytic subunit of the DNA polymerase alpha-primase complex, required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis, Chr XIV from 430089-434495, Verified ORF YDR409W 39.28 0.97 16 552.3637 1 YDR409W SIZ1 SGDID:S000002817,SUMO ligase that promotes the attachment of sumo (Smt3p; small ubiquitin-related modifier) to proteins; binds Ubc9p and may bind septins; specifically required for sumoylation of septins in vivo; localized to the septin ring, Chr IV from 1289398-1292112, Verified ORF YDR365C 35.168 1.00 8 318.0147 1 YDR365C ESF1 SGDID:S000002773,Nucleolar protein involved in pre-rRNA processing; depletion causes severely decreased 18S rRNA levels, Chr IV from 1206375-1204489, reverse complement, Verified ORF YMR272C 11.03 1.00 6 760.4674 1 YMR272C SCS7 SGDID:S000004885,Sphingolipid alpha-hydroxylase, functions in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids, has both cytochrome b5-like and hydroxylase\desaturase domains, not essential for growth, Chr XIII from 810776-809622, reverse complement, Verified ORF YIR036C 14.37 1.00 4 389.142 1 YIR036C YIR036C SGDID:S000001475,Putative protein of unknown function; sequence similarity with short-chain dehydrogenase\reductase family members; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YIR036C is a non-essential gene, Chr IX from 422862-422071, reverse complement, Uncharacterized ORF YJL039C 63.749 0.99 10 217.1034 1 YJL039C NUP192 SGDID:S000003576,Essential structural subunit of the nuclear pore complex (NPC), localizes to the nuclear periphery of nuclear pores, homologous to human p205, Chr X from 373716-368665, reverse complement, Verified ORF YPR024W 37.688 0.90 4 133.5378 1 YPR024W YME1 SGDID:S000006228,Subunit, with Mgr1p, of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; mutation causes an elevated rate of mitochondrial turnover, Chr XVI from 610478-612721, Verified ORF YKL143W 13.45 0.97 4 403.2871 1 YKL143W LTV1 SGDID:S000001626,Protein required for growth at low temperature, Chr XI from 176786-178177, Verified ORF YKR103W 44.98 0.99 6 184.617 1 YKR103W NFT1 SGDID:S000001811,Putative transporter of the multidrug resistance-associated protein (MRP) subfamily; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds., Chr XI from 652718-656374, Verified ORF YDL205C 13.96 0.82 1 82.117 1 YDL205C HEM3 SGDID:S000002364,Phorphobilinogen deaminase, catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p, Chr IV from 93746-92763, reverse complement, Verified ORF YLR259C 29.358 1.00 312 14857.0655 1 YLR259C HSP60 SGDID:S000004249,Tetradecameric mitochondrial chaperonin required for ATP-dependent folding of precursor polypeptides and complex assembly; prevents aggregation and mediates protein refolding after heat shock; role in mtDNA transmission; similarity to groEL, Chr XII from 665004-663286, reverse complement, Verified ORF YDL081C 2.74 1.00 50 25510.8162 1 YDL081C RPP1A SGDID:S000002239,Ribosomal protein P1 alpha, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; accumulation of P1 in the cytoplasm is regulated by phosphorylation and interaction with the P2 stalk component, Chr IV from 310122-309802, reverse complement, Verified ORF YKL073W 37.5 1.00 15 559.197 1 YKL073W LHS1 SGDID:S000001556,Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide translocation and folding; member of the Hsp70 family; localizes to the lumen of the ER; regulated by the unfolded protein response pathway, Chr XI from 296074-298719, Verified ORF YDL154W 34.616 0.98 11 435.3582 1 YDL154W MSH5 SGDID:S000002313,Protein of the MutS family, forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans, Chr IV from 178335-181040, Verified ORF YGL144C 25.68 0.85 2 92.5462 1 YGL144C ROG1 SGDID:S000003112,Protein with putative serine active lipase domain, Chr VII from 234512-232455, reverse complement, Verified ORF YDR496C 22.09 1.00 6 379.7173 1 YDR496C PUF6 SGDID:S000002904,Pumilio-homology domain protein that binds ASH1 mRNA at PUF consensus sequences in the 3' UTR and represses its translation, resulting in proper asymmetric localization of ASH1 mRNA, Chr IV from 1443395-1441425, reverse complement, Verified ORF YBR088C 15.27 1.00 55 5035.3372 1 YBR088C POL30 SGDID:S000000292,Proliferating cell nuclear antigen (PCNA), functions as the sliding clamp for DNA polymerase delta; may function as a docking site for other proteins required for mitotic and meiotic chromosomal DNA replication and for DNA repair, Chr II from 425760-424984, reverse complement, Verified ORF YDR390C 26.03 0.72 2 77.338 1 YDR390C UBA2 SGDID:S000002798,Nuclear protein that acts as a heterodimer with Aos1p to activate Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability, Chr IV from 1256839-1254929, reverse complement, Verified ORF YFL042C 29.1 1.00 13 624.5328 1 YFL042C YFL042C SGDID:S000001852,Putative protein of unknown function; YFL042C is not an essential gene, Chr VI from 47744-45720, reverse complement, Uncharacterized ORF YFR006W 23.532 1.00 5 297.0407 1 YFR006W YFR006W SGDID:S000001902,Putative X-Pro aminopeptidase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YFR006W is not an essential gene, Chr VI from 156139-157746, Uncharacterized ORF YBL036C 14.678 1.00 20 1904.8817 1 YBL036C YBL036C SGDID:S000000132,Single-domain racemase, possibly non-specific due to the lack of the second domain, which presumably determines specificity, Chr II from 151223-150450, reverse complement, Verified ORF YGL202W 20.27 1.00 91 6276.139 1 YGL202W ARO8 SGDID:S000003170,Aromatic aminotransferase, expression is regulated by general control of amino acid biosynthesis, Chr VII from 116063-117565, Verified ORF YOL147C 9.28 0.99 19 2833.6468 1 YOL147C PEX11 SGDID:S000005507,Peroxisomal membrane protein required for peroxisome proliferation and medium-chain fatty acid oxidation, most abundant protein in the peroxisomal membrane, regulated by Adr1p and Pip2p-Oaf1p, promoter contains ORE and UAS1-like elements, Chr XV from 48642-47932, reverse complement, Verified ORF YCL040W 20.229 1.00 40 2764.3338 1 YCL040W GLK1 SGDID:S000000545,Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources, Chr III from 50838-52340, Verified ORF YDL146W 22.68 0.97 1 59.7906 1 YDL146W LDB17 SGDID:S000002305,Protein of unknown function; GFP-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; null mutant shows a reduced affinity for the alcian blue dye suggesting a decreased net negative charge of the cell surface, Chr IV from 192751-194226, Verified ORF YPL145C 18.524 1.00 61 4603.6253 1 YPL145C KES1 SGDID:S000006066,Member of the oxysterol binding protein family, which includes seven yeast homologs; involved in negative regulation of Sec14p-dependent Golgi complex secretory functions, peripheral membrane protein that localizes to the Golgi complex, Chr XVI from 279698-278394, reverse complement, Verified ORF YER073W 25.665 1.00 39 2124.3606 1 YER073W ALD5 SGDID:S000000875,Mitochondrial aldehyde dehydrogenase, involved in regulation or biosynthesis of electron transport chain components and acetate formation; activated by K+; utilizes NADP+ as the preferred coenzyme; constitutively expressed, Chr V from 304027-305589, Verified ORF YHR042W 31.278 1.00 36 1609.0459 1 YHR042W NCP1 SGDID:S000001084,NADP-cytochrome P450 reductase; involved in ergosterol biosynthesis; associated and coordinately regulated with Erg11p, Chr VIII from 190536-192611, Verified ORF YPL158C 25.22 0.98 21 1140.7886 1 YPL158C YPL158C SGDID:S000006079,Hypothetical protein, Chr XVI from 254309-252033, reverse complement, Uncharacterized ORF YJR007W 15.919 1.00 50 4390.9564 1 YJR007W SUI2 SGDID:S000003767,Alpha subunit of the translation initiation factor eIF2, involved in the identification of the start codon; phosphorylation of Ser51 is required for regulation of translation by inhibiting the exchange of GDP for GTP, Chr X from 450935-451849, Verified ORF YNL069C 12.92 1.00 176 19043.8637 1 YNL069C RPL16B SGDID:S000005013,N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Ap, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p, Chr XIV from 495002-494975,494525-493957, reverse complement, Verified ORF YMR189W 31.31 1.00 5 223.2501 1 YMR189W GCV2 SGDID:S000004801,P subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm, Chr XIII from 637499-640603, Verified ORF YKL105C 49.007 0.65 8 148.3372 1 YKL105C YKL105C SGDID:S000001588,Putative protein of unknown function, Chr XI from 242227-238829, reverse complement, Uncharacterized ORF YOR137C 20.086 0.72 6 300.6735 1 YOR137C SIA1 SGDID:S000005663,Protein of unassigned function involved in activation of the Pma1p plasma membrane H+-ATPase by glucose, Chr XV from 583682-581814, reverse complement, Verified ORF YPL163C 1.97 0.92 1 652.8697 1 YPL163C SVS1 SGDID:S000006084,Cell wall and vacuolar protein, required for wild-type resistance to vanadate, Chr XVI from 242699-241917, reverse complement, Verified ORF YMR047C 18.71 0.99 2 147.9436 1 YMR047C NUP116 SGDID:S000004650,Subunit of the nuclear pore complex (NPC) that is localized to both sides of the pore; contains a repetitive GLFG motif that interacts with mRNA export factor Mex67p and with karyopherin Kap95p; homologous to Nup100p, Chr XIII from 366704-363363, reverse complement, Verified ORF YOR161W-A 0.48 0.90 28 73394.6182 1 YOR161W-A YOR161W-A SGDID:S000028713,Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching, Chr XV from 637575-637655, Dubious ORF YER131W 3.53 1.00 39 15445.2454 2 YGL189C,YER131W RPS26B SGDID:S000000933,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein, Chr V from 423948-424307, Verified ORF YPL036W 20.82 0.92 3 185.3246 1 YPL036W PMA2 SGDID:S000005957,Plasma membrane H+-ATPase, isoform of Pma1p, involved in pumping protons out of the cell; regulator of cytoplasmic pH and plasma membrane potential, Chr XVI from 482841-485684, Verified ORF YCL010C 13.92 0.82 1 82.353 1 YCL010C SGF29 SGDID:S000000516,SaGa associated Factor 29kDa; Probable 29kKDa Subunit of SAGA histone acetyltransferase complex, Chr III from 104350-103571, reverse complement, Verified ORF YNL293W 26.164 1.00 13 694.6149 1 YNL293W MSB3 SGDID:S000005237,GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exocytosis via its action on Sec4p, also required for proper actin organization; similar to Msb4p; both Msb3p and Msb4p localize to sites of polarized growth, Chr XIV from 80640-82541, Verified ORF YDR172W 24.607 1.00 39 2215.6994 1 YDR172W SUP35 SGDID:S000002579,Translation termination factor eRF3; altered protein conformation creates the [PSI(+)] prion, a dominant cytoplasmically inherited protein aggregate that alters translational fidelity and creates a nonsense suppressor phenotype, Chr IV from 808321-810378, Verified ORF YJR024C 10.327 0.95 2 257.2079 1 YJR024C YJR024C SGDID:S000003785,Putative protein of unknown function; localizes to the cytoplasm; potential substrate of Smt3p sumoylation; expression downregulated by the antifungal drug caspofungin and deletion mutant exhibits enhanced caspofungin resistance, Chr X from 470879-470145, reverse complement, Uncharacterized ORF YBR042C 16.17 0.98 27 2287.6244 1 YBR042C YBR042C SGDID:S000000246,Hypothetical protein, Chr II from 321609-320416, reverse complement, Uncharacterized ORF YNL085W 36.149 1.00 3 116.0192 1 YNL085W MKT1 SGDID:S000005029,Protein that forms a complex with Pbp1p that may mediate posttranscriptional regulation of HO endonuclease; involved in propagation of M2 dsRNA satellite of L-A virus, Chr XIV from 467133-469625, Verified ORF YNR046W 3 0.67 8 2497.747 1 YNR046W TRM112 SGDID:S000005329,Subunit of an adoMet-dependent tRNA methyltransferase (MTase) complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; putative zinc binding subunit of other MTase-related proteins, Chr XIV from 707790-708197, Verified ORF YML069W 21.188 0.99 3 195.9617 1 YML069W POB3 SGDID:S000004534,Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure, Chr XIII from 135500-137158, Verified ORF YML125C 14.869 1.00 4 376.0825 1 YML125C YML125C SGDID:S000004594,Essential protein required for maturation of Gas1p and Pho8p; GFP-fusion protein localizes to the endoplasmic reticulum; null mutants have a cell separation defect, Chr XIII from 21700-20762, reverse complement, Uncharacterized ORF YOL057W 33.438 1.00 11 459.8935 1 YOL057W YOL057W SGDID:S000005418,Putative metalloprotease, Chr XV from 220766-222901, Uncharacterized ORF YKL145W 26.59 1.00 16 841.2141 1 YKL145W RPT1 SGDID:S000001628,One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for optimal CDC20 transcription; interacts with Rpn12p and the E3 ubiquitin-protein ligase Ubr1p, Chr XI from 174218-175621, Verified ORF YLR314C 26.84 1.00 11 572.9478 1 YLR314C CDC3 SGDID:S000004306,Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM, Chr XII from 764137-762575, reverse complement, Verified ORF YFR030W 50.388 1.00 7 194.2118 1 YFR030W MET10 SGDID:S000001926,Subunit alpha of assimilatory sulfite reductase, which is responsible for the conversion of sulfite into sulfide, Chr VI from 213300-216407, Verified ORF YNL287W 38.12 1.00 49 1797 1 YNL287W SEC21 SGDID:S000005231,Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p forms the COPI coat; involved in ER to Golgi transport of selective cargo, Chr XIV from 91994-94801, Verified ORF YGR103W 27.188 1.00 16 822.7116 1 YGR103W NOP7 SGDID:S000003335,Nucleolar protein involved in rRNA processing and 60S ribosomal subunit biogenesis; constituent of several different pre-ribosomal particles, Chr VII from 695421-697238, Verified ORF YDL126C 39.53 1.00 275 9725.4743 1 YDL126C CDC48 SGDID:S000002284,ATPase in ER, nuclear membrane and cytosol with homology to mammalian p97; in a complex with Npl4p and Ufd1p participates in retrotranslocation of ubiquitinated proteins from the ER into the cytosol for degradation by the proteasome, Chr IV from 238664-236157, reverse complement, Verified ORF YLR061W 4.41 1.00 89 28213.4586 1 YLR061W RPL22A SGDID:S000004051,Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22Bp and to rat L22 ribosomal protein, Chr XII from 263195-263206,263596-263949, Verified ORF YJL005W 88.4140000000001 1.00 15 237.1783 1 YJL005W CYR1 SGDID:S000003542,Adenylate cyclase, required for cAMP production and cAMP-dependent protein kinase signaling; involved in cell cycle control and glucose and nitrogen repression of sporulation, Chr X from 425073-431153, Verified ORF YDR103W 34.098 0.84 4 137.7575 1 YDR103W STE5 SGDID:S000002510,Scaffold protein that, in response to pheromone, shuttles from the nucleus to the plasma membrane and assembles kinases Ste11p, Ste7p, and Fus3p into a specific signaling complex; active oligomeric form interacts with Ste4p-Ste18p complex, Chr IV from 658347-661100, Verified ORF YOR362C 11.198 1.00 31 3870.1352 1 YOR362C PRE10 SGDID:S000005889,20S proteasome alpha-type subunit, Chr XV from 1018744-1017878, reverse complement, Verified ORF YBR162C 6.28 0.99 1 220.3842 1 YBR162C TOS1 SGDID:S000000366,Covalently-bound cell wall protein of unknown function; identified as a cell cycle regulated SBF target gene; deletion mutants are highly resistant to treatment with beta-1,3-glucanase; has sequence similarity to YJL171C, Chr II from 564565-563198, reverse complement, Uncharacterized ORF YJR006W 21.51 1.00 8 519.9415 1 YJR006W HYS2 SGDID:S000003766,DNA polymerase III (delta) subunit, essential for cell viability; involved in DNA replication and DNA repair, Chr X from 449117-450580, Verified ORF YMR276W 8.5 1.00 19 3124.9249 1 YMR276W DSK2 SGDID:S000004889,Nuclear-enriched ubiquitin-like polyubiquitin-binding protein, required for spindle pole body (SPB) duplication and for transit through the G2\M phase of the cell cycle, involved in proteolysis, interacts with the proteasome, Chr XIII from 818826-819947, Verified ORF YJL115W 7.42 0.97 2 365.5129 1 YJL115W ASF1 SGDID:S000003651,Nucleosome assembly factor, involved in chromatin assembly after DNA replication, anti-silencing protein that causes derepression of silent loci when overexpressed, Chr X from 196207-197046, Verified ORF YLR044C 25.748 1.00 1530 83071.6511 1 YLR044C PDC1 SGDID:S000004034,Major of three pyruvate decarboxylase isozymes, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde; subject to glucose-, ethanol-, and autoregulation; involved in amino acid catabolism, Chr XII from 234082-232391, reverse complement, Verified ORF YGR251W 10.496 0.85 3 339.6419 1 YGR251W YGR251W SGDID:S000003483,Putative protein of unknown function; deletion mutant has defects in pre-rRNA processing; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the nucleolus; YGR251W is an essential gene, Chr VII from 995644-996234, Uncharacterized ORF YBL030C 14.86 1.00 85 7996.5936 1 YBL030C PET9 SGDID:S000000126,Major ADP\ATP carrier of the mitochondrial inner membrane, exchanges cytosolic ADP for mitochondrially synthesized ATP; required for viability in many common lab strains carrying a mutation in the polymorphic SAL1 gene, Chr II from 164000-163044, reverse complement, Verified ORF YLR276C 29.965 1.00 76 3545.7182 1 YLR276C DBP9 SGDID:S000004266,ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 60S ribosomal subunit, Chr XII from 696832-695048, reverse complement, Verified ORF YJL099W 28.36 0.99 7 341.611 1 YJL099W CHS6 SGDID:S000003635,Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p localization, Chr X from 239332-241572, Verified ORF YOR217W 38.716 1.00 8 288.8713 1 YOR217W RFC1 SGDID:S000005743,Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon, Chr XV from 749302-751887, Verified ORF YGR065C 13.48 0.75 3 233.3444 1 YGR065C VHT1 SGDID:S000003297,High-affinity plasma membrane H+-biotin (vitamin H) symporter; mutation results in fatty acid auxotrophy; 12 transmembrane domain containing major facilitator subfamily member; mRNA levels negatively regulated by iron deprivation and biotin, Chr VII from 619862-618081, reverse complement, Verified ORF YLR422W 78.593 0.98 7 122.0239 1 YLR422W YLR422W SGDID:S000004414,Hypothetical protein, Chr XII from 965894-971692, Uncharacterized ORF YGR061C 47.15 1.00 160 4743.9838 1 YGR061C ADE6 SGDID:S000003293,Formylglycinamidine-ribonucleotide (FGAM)-synthetase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway, Chr VII from 615969-611893, reverse complement, Verified ORF YBR049C 29.28 1.00 50 2387.2826 1 YBR049C REB1 SGDID:S000000253,RNA polymerase I enhancer binding protein; DNA binding protein which binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription, Chr II from 336816-334384, reverse complement, Verified ORF YFR010W 25.94 1.00 19 1023.973 1 YFR010W UBP6 SGDID:S000001906,Ubiquitin-specific protease situated in the base subcomplex of the 26S proteasome, releases free ubiquitin from branched polyubiquitin chains; deletion causes hypersensitivity to cycloheximide and other toxic compounds, Chr VI from 165060-166559, Verified ORF YML124C 13.23 1.00 13 1373.689 1 YML124C TUB3 SGDID:S000004593,Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; expressed at lower level than Tub1p, Chr XIII from 23684-23660,23361-22049, reverse complement, Verified ORF YBR111C 6.54 0.96 1 205.2099 1 YBR111C YSA1 SGDID:S000000315,Nudix hydrolase family member with ADP-ribose pyrophosphatase activity, Chr II from 461867-461172, reverse complement, Verified ORF YJR097W 6.058 0.95 1 219.2296 1 YJR097W JJJ3 SGDID:S000003858,Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein, Chr X from 612331-612849, Verified ORF YDL178W 21.835 0.98 9 564.7032 1 YDL178W DLD2 SGDID:S000002337,D-lactate dehydrogenase, located in the mitochondrial matrix, Chr IV from 139523-141115, Verified ORF YOR374W 29.009 1.00 55 2650.5429 1 YOR374W ALD4 SGDID:S000005901,Mitochondrial aldehyde dehydrogenase, required for growth on ethanol and conversion of acetaldehyde to acetate; activity is K+ dependent; utilizes NADP+ or NAD+ equally as coenzymes; expression is glucose repressed, Chr XV from 1039838-1041397, Verified ORF YKR028W 43.857 0.98 3 93.7159 1 YKR028W SAP190 SGDID:S000001736,Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap155p, and Sap185p, Chr XI from 493900-497196, Verified ORF YIR021W 19.039 0.69 4 202.6608 1 YIR021W MRS1 SGDID:S000001460,Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA, Chr IX from 397291-398382, Verified ORF YBL088C 108.873 1.00 17 218.2899 1 YBL088C TEL1 SGDID:S000000184,Protein kinase, primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; functionally redundant with Mec1p; homolog of human ataxia telangiectasia (ATM) gene, Chr II from 59379-51016, reverse complement, Verified ORF YML105C 11.92 1.00 10 1172.8126 1 YML105C SEC65 SGDID:S000004573,Subunit of the signal recognition particle (SRP), involved in protein targeting to the ER; interacts with Srp54p; homolog of mammalian SRP19, Chr XIII from 58687-57866, reverse complement, Verified ORF YKL035W 23.57 1.00 79 4685.6777 1 YKL035W UGP1 SGDID:S000001518,UDP-glucose pyrophosphorylase (UGPase), catalyses the reversible formation of UDP-Glc from glucose 1-phosphate and UTP, involved in a wide variety of metabolic pathways, expression modulated by Pho85p through Pho4p, Chr XI from 369534-371033, Verified ORF YGR027C 4.26 0.99 33 10721.2259 2 YLR333C,YGR027C RPS25A SGDID:S000003259,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Bp and has similarity to rat S25 ribosomal protein, Chr VII from 534462-534136, reverse complement, Verified ORF YNL012W 24.3 0.83 8 382.0029 1 YNL012W SPO1 SGDID:S000004957,Meiosis-specific protein with similarity to phospholipase B, required for meiotic spindle pole body duplication and separation; required for spore formation, Chr XIV from 609687-609791,609876-611666, Verified ORF YDR141C 76.4 0.99 5 90.5767 1 YDR141C DOP1 SGDID:S000002548,Protein of unknown function, essential for viability, involved in establishing cellular polarity and morphogenesis; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern, Chr IV from 739994-734898, reverse complement, Verified ORF YGL171W 23.05 1.00 10 606.5044 1 YGL171W ROK1 SGDID:S000003139,ATP-dependent RNA helicase of the DEAD box family; required for 18S rRNA synthesis, Chr VII from 182396-184090, Verified ORF YLR115W 40.538 0.88 5 151.7383 1 YLR115W CFT2 SGDID:S000004105,Subunit of the mRNA cleavage and polyadenlylation factor (CPF); required for pre-mRNA cleavage, polyadenylation and poly(A) site recognition, 43% similarity with the mammalian CPSF-100 protein., Chr XII from 377986-380565, Verified ORF YEL031W 41.57 1.00 31 1042.5252 1 YEL031W SPF1 SGDID:S000000757,P-type ATPase, ion transporter of the ER membrane involved in ER function and Ca2+ homeostasis; required for regulating Hmg2p degradation; confers sensitivity to a killer toxin (SMKT) produced by Pichia farinosa KK1, Chr V from 90258-93905, Verified ORF YBR151W 16.01 0.97 7 592.9026 1 YBR151W APD1 SGDID:S000000355,Protein of unknown function, required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; localizes to both cytoplasm and nucleus, Chr II from 545022-545972, Verified ORF YDL147W 18.268 0.97 3 222.6931 1 YDL147W RPN5 SGDID:S000002306,Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to mammalian p55 subunit and to another S. cerevisiae regulatory subunit, Rpn7p, Chr IV from 190925-192262, Verified ORF YJL129C 30.94 0.92 7 290.9849 1 YJL129C TRK1 SGDID:S000003665,Component of the Trk1p-Trk2p potassium transport system; 180 kDa high affinity potassium transporter, Chr X from 177225-173518, reverse complement, Verified ORF YDR533C 13.718 0.85 1 86.6229 1 YDR533C HSP31 SGDID:S000002941,Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp32p, Hsp33p, and Sno4p; member of the DJ-1\ThiJ\PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease; exists as a dimer, Chr IV from 1502152-1501439, reverse complement, Verified ORF YKL191W 11.92 1.00 6 703.6876 1 YKL191W DPH2 SGDID:S000001674,Protein required, along with Dph1p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph1p and Kti11p, Chr XI from 81040-82644, Verified ORF YDL100C 13.97 1.00 5 500.3553 1 YDL100C GET3 SGDID:S000002258,ATPase, subunit of the GET complex; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion; involved in resistance to heat and metal stress, Chr IV from 283176-282112, reverse complement, Verified ORF YGR198W 30.57 0.87 4 159.1434 1 YGR198W YGR198W SGDID:S000003430,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; YGR198W is an essential gene, Chr VII from 894698-897151, Uncharacterized ORF YBR177C 25.594 0.99 1 54.0756 1 YBR177C EHT1 SGDID:S000000381,Possible serine hydrolase, localized to both lipid particles and mitochondrial outer membrane; may be involved in lipid metabolism; null mutant slightly temperature sensitive at 37C, Chr II from 586157-584802, reverse complement, Verified ORF YJL034W 30.79 1.00 186 8445.1655 1 YJL034W KAR2 SGDID:S000003571,ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p, Chr X from 381244-383292, Verified ORF YBR081C 63.47 1.00 12 264.3124 1 YBR081C SPT7 SGDID:S000000285,Subunit of the SAGA transcriptional regulatory complex, involved in proper assembly of the complex; also present as a C-terminally truncated form in the SLIK\SALSA transcriptional regulatory complex, Chr II from 405245-401247, reverse complement, Verified ORF YNR059W 26.915 0.98 6 305.4132 1 YNR059W MNT4 SGDID:S000005342,Putative alpha-1,3-mannosyltransferase, not required for protein O-glycosylation, Chr XIV from 736803-738545, Verified ORF YDR034C 25.908 0.65 4 140.2957 1 YDR034C LYS14 SGDID:S000002441,Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway; requires 2-aminoadipate semialdehyde as co-inducer, Chr IV from 512106-509734, reverse complement, Verified ORF YBR033W 27.75 0.99 13 648.3663 1 YBR033W YBR033W SGDID:S000000237,Non-essential protein of unknown function, Chr II from 301944-304703, Uncharacterized ORF YDR144C 14.11 1.00 8 792.6252 1 YDR144C MKC7 SGDID:S000002551,GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p, Chr IV from 746098-744308, reverse complement, Verified ORF YIL094C 16.45 1.00 33 2804.4838 1 YIL094C LYS12 SGDID:S000001356,Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine, in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate, Chr IX from 187629-186514, reverse complement, Verified ORF YIL002W-A 6.75 1.00 16 3313.7605 1 YIL002W-A YIL002W-A SGDID:S000028835,Identified by expression profiling and mass spectrometry, Chr IX from 350298-350507, Uncharacterized ORF YAL049C 10.388 1.00 7 942.0436 1 YAL049C YAL049C SGDID:S000000047,Hypothetical protein, Chr I from 52596-51856, reverse complement, Uncharacterized ORF YMR078C 37.65 0.98 6 218.3319 1 YMR078C CTF18 SGDID:S000004683,Subunit of a complex with Ctf8p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion; may have overlapping functions with Rad24p in the DNA damage replication checkpoint, Chr XIII from 424727-422502, reverse complement, Verified ORF YIL078W 39.02 1.00 145 5195.0011 1 YIL078W THS1 SGDID:S000001340,Threonyl-tRNA synthetase, essential cytoplasmic protein, Chr IX from 212496-214700, Verified ORF YOL162W 5.15 0.83 4 901.2302 1 YOL162W YOL162W SGDID:S000005522,Hypothetical protein, member of the Dal5p subfamily of the major facilitator family, Chr XV from 10118-10765, Uncharacterized ORF YKR084C 23.026 0.96 3 174.8553 1 YKR084C HBS1 SGDID:S000001792,GTP binding protein with sequence similarity to the elongation factor class of G proteins, EF-1alpha and Sup35p; associates with Dom34p, and shares a similar genetic relationship with genes that encode ribosomal protein components, Chr XI from 598532-596697, reverse complement, Verified ORF YKL209C 37.61 0.97 6 216.3338 1 YKL209C STE6 SGDID:S000001692,ATP-binding cassette (ABC) transporter required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport, contains 12 transmembrane domains and two ATP binding domains, expressed only in MATa cells, Chr XI from 46296-42424, reverse complement, Verified ORF YNR053C 31.27 1.00 22 983.5574 1 YNR053C NOG2 SGDID:S000005336,Putative GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation, Chr XIV from 723113-722304,721772-721122, reverse complement, Verified ORF YHR121W 11.329 0.93 3 344.2845 1 YHR121W LSM12 SGDID:S000001163,Protein containing an Lsm domain and an AD domain; may bind RNA and have a role in RNA processing, Chr VIII from 352759-353322, Uncharacterized ORF YBR246W 16.11 1.00 11 954.5574 1 YBR246W YBR246W SGDID:S000000450,Hypothetical protein, Chr II from 711586-712749, Uncharacterized ORF YKL180W 7.98 1.00 164 28730.6776 1 YKL180W RPL17A SGDID:S000001663,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Bp and has similarity to E. coli L22 and rat L17 ribosomal proteins; copurifies with the components of the outer kinetochore DASH complex, Chr XI from 109274-109582,109889-110134, Verified ORF YGR037C 6.57 1.00 95 20214.5067 1 YGR037C ACB1 SGDID:S000003269,Acyl-CoA-binding protein, transports newly synthesized acyl-CoA esters from fatty acid synthetase (Fas1p-Fas2p) to acyl-CoA-consuming processes, Chr VII from 559998-559735, reverse complement, Verified ORF YDR071C 9.19 1.00 31 4715.7534 1 YDR071C PAA1 SGDID:S000002478,Polyamine acetyltransferase; acetylates polyamines such as putrescine, spermidine and spermine; may be involved in transcription and\or DNA replication via regulation of levels of polyamines bound to chromosomal DNA, Chr IV from 589400-588825, reverse complement, Verified ORF YHR107C 22.218 1.00 12 755.0595 1 YHR107C CDC12 SGDID:S000001149,Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM, Chr VIII from 328039-326816, reverse complement, Verified ORF YLL066C 49.33 0.99 5 140.281 6 YDR545W,YLR467W,YLR466W,YOR396W,YLL066C,YML133C YLL066C SGDID:S000003989,Putative protein of unknown function with similarity to helicases; YLL066C is not an essential gene, Chr XII from 9836-9550,9450-6120, reverse complement, Uncharacterized ORF YER112W 3.52 0.92 4 1461.5378 1 YER112W LSM4 SGDID:S000000914,Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA, Chr V from 387228-387791, Verified ORF YML123C 12.99 1.00 16 1721.9309 1 YML123C PHO84 SGDID:S000004592,High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p, Chr XIII from 25801-24038, reverse complement, Verified ORF YCR018C-A 0.44 0.78 1 2478.2598 1 YCR018C-A YCR018C-A SGDID:S000007230,Similar to probable membrane protein YLR334C and ORF YOL106W, Chr III from 151860-151606, reverse complement, Dubious ORF YBR191W 7.258 1.00 45 8667.6319 2 YBR191W,YPL079W RPL21A SGDID:S000000395,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Bp and has similarity to rat L21 ribosomal protein, Chr II from 606265-606275,606664-607135, Verified ORF YIL038C 30.99 0.94 1 42.4044 1 YIL038C NOT3 SGDID:S000001300,Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation, Chr IX from 282651-280141, reverse complement, Verified ORF YGL083W 36.797 0.71 2 53.9486 1 YGL083W SCY1 SGDID:S000003051,Putative kinase, suppressor of GTPase mutant, similar to bovine rhodopsin kinase, Chr VII from 353061-355475, Verified ORF YDR346C 16.38 1.00 50 4267.377 1 YDR346C SVF1 SGDID:S000002754,Protein with a potential role in cell survival pathways, required for the diauxic growth shift; expression in mammalian cells increases survival under conditions inducing apoptosis, Chr IV from 1168653-1167208, reverse complement, Verified ORF YDR001C 40.869 1.00 3 102.62 1 YDR001C NTH1 SGDID:S000002408,Neutral trehalase, degrades trehalose; required for thermotolerance and may mediate resistance to other cellular stresses; may be phosphorylated by Cdc28p, Chr IV from 452472-450217, reverse complement, Verified ORF YBL045C 18.28 1.00 39 2982.5884 1 YBL045C COR1 SGDID:S000000141,Core subunit of the ubiquinol-cytochrome c reductase complex (bc1 complex), which is a component of the mitochondrial inner membrane electron transport chain, Chr II from 135519-134146, reverse complement, Verified ORF YDR091C 24.116 1.00 63 3652.0791 1 YDR091C RLI1 SGDID:S000002498,Essential iron-sulfur protein required for ribosome biogenesis and translation initiation; facilitates binding of a multifactor complex (MFC) of translation initiation factors to the small ribosomal subunit; predicted ABC family ATPase, Chr IV from 628531-626705, reverse complement, Verified ORF YMR229C 94.146 1.00 50 742.4599 1 YMR229C RRP5 SGDID:S000004842,Protein required for the synthesis of both 18S and 5.8S rRNA; C-terminal region is crucial for the formation of 18S rRNA and N-terminal region is required for the 5.8S rRNA; component of small ribosomal subunit (SSU) processosome, Chr XIII from 731122-725933, reverse complement, Verified ORF YLR149C 20.92 0.91 23 1398.6609 1 YLR149C YLR149C SGDID:S000004139,Putative protein of unknown function; YLR149C is not an essential gene, Chr XII from 439824-437632, reverse complement, Uncharacterized ORF YKR092C 8.29 0.99 2 333.8993 1 YKR092C SRP40 SGDID:S000001800,Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140, Chr XI from 613527-612307, reverse complement, Verified ORF YIL156W 41.84 1.00 16 534.6052 1 YIL156W UBP7 SGDID:S000001418,Ubiquitin-specific protease that cleaves ubiquitin-protein fusions, Chr IX from 48091-51306, Verified ORF YOR286W 7.9 0.99 3 525.5744 1 YOR286W YOR286W SGDID:S000005812,The authentic, non-tagged protein was localized to the mitochondria, Chr XV from 850279-850728, Uncharacterized ORF YOR315W 14.948 0.99 2 185.1769 1 YOR315W SFG1 SGDID:S000005842,Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate, Chr XV from 904757-905797, Verified ORF YNL010W 10.46 1.00 17 2272.0723 1 YNL010W YNL010W SGDID:S000004955,Hypothetical protein, Chr XIV from 613636-614361, Uncharacterized ORF YMR208W 13.28 0.93 1 97.9015 1 YMR208W ERG12 SGDID:S000004821,Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate, Chr XIII from 684466-685797, Verified ORF YNR019W 12.17 0.97 2 222.8517 1 YNR019W ARE2 SGDID:S000005302,Acyl-CoA:sterol acyltransferase, isozyme of Are1p; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the presence of oxygen, Chr XIV from 665341-667269, Verified ORF YPL235W 25.75 0.99 6 322.4884 1 YPL235W RVB2 SGDID:S000006156,Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; member of the RUVB-like protein family, Chr XVI from 103232-104647, Verified ORF YFL010C 2.93 1.00 41 19562.3555 1 YFL010C WWM1 SGDID:S000001884,WW domain containing protein of unknown function; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes Gi phase growth arrest and clonal death that is suppressed by overexpression of MCA1, Chr VI from 115737-115102, reverse complement, Verified ORF YBR218C 48.807 1.00 57 1632.6671 1 YBR218C PYC2 SGDID:S000000422,Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc1p but differentially regulated; mutations in the human homolog are associated with lactic acidosis, Chr II from 662244-658702, reverse complement, Verified ORF YNL079C 15.59 1.00 79 7084.1196 1 YNL079C TPM1 SGDID:S000005023,Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently, Chr XIV from 479166-478567, reverse complement, Verified ORF YJL207C 88.557 0.97 10 153.1276 1 YJL207C YJL207C SGDID:S000003743,Protein of unknown function, proposed to function as a large AP-1 accessory protein; colocalizes with clathrin to the late-Golgi apparatus; YJL207C is a non-essential gene, Chr X from 47433-41389, reverse complement, Uncharacterized ORF YHR104W 18.5 1.00 4 302.2686 1 YHR104W GRE3 SGDID:S000001146,Aldose reductase involved in methylglyoxal, d-xylose and arabinose metabolism; stress induced (osmotic, ionic, oxidative, heat shock, starvation and heavy metals); regulated by the HOG pathway, Chr VIII from 323412-324395, Verified ORF YLR089C 17.77 1.00 12 944.0581 1 YLR089C YLR089C SGDID:S000004079,Putative alanine transaminase (glutamic pyruvic transaminase), Chr XII from 320016-318238, reverse complement, Uncharacterized ORF YOR361C 37.538 1.00 67 2495.2185 1 YOR361C PRT1 SGDID:S000005888,Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes, Chr XV from 1017650-1015359, reverse complement, Verified ORF YLL008W 30.44 1.00 16 734.8187 1 YLL008W DRS1 SGDID:S000003931,Nucleolar DEAD-box protein required for ribosome assembly and function, including synthesis of 60S ribosomal subunits; constituent of 66S pre-ribosomal particles, Chr XII from 131728-133986, Verified ORF YPL226W 59.398 1.00 115 2706.6427 1 YPL226W NEW1 SGDID:S000006147,ATP binding cassette family member; Asn\Gln-rich rich region supports [NU+] prion formation, susceptibility to [PSI+] prion induction and aggregation of a fragment of the human Machado-Joseph Disease protein, Chr XVI from 121767-125357, Verified ORF YPL111W 13.658 1.00 4 409.4282 1 YPL111W CAR1 SGDID:S000006032,Arginase, responsible for arginine degradation, expression responds to both induction by arginine and nitrogen catabolite repression; disruption enhances freeze tolerance, Chr XVI from 339943-340944, Verified ORF YML031W 17.77 0.74 10 582.1691 1 YML031W NDC1 SGDID:S000004493,Nuclear envelope protein with multiple putative transmembrane domains, required for nuclear pore complex assembly and spindle pole body duplication; required for meiosis II, Chr XIII from 214189-216156, Verified ORF YHR146W 19.73 1.00 16 1133.6991 1 YHR146W CRP1 SGDID:S000001189,Protein that binds to cruciform DNA structures, Chr VIII from 390303-391700, Verified ORF YOR065W 10.54 0.98 6 779.9048 1 YOR065W CYT1 SGDID:S000005591,Cytochrome c1, component of the mitochondrial respiratory chain; expression is regulated by the heme-activated, glucose-repressed Hap2p\3p\4p\5p CCAAT-binding complex, Chr XV from 447441-448370, Verified ORF YNR014W 4.48 0.98 42 12844.0581 1 YNR014W YNR014W SGDID:S000005297,Hypothetical protein, Chr XIV from 652467-653105, Uncharacterized ORF YOL061W 18.16 1.00 15 1154.7296 1 YOL061W PRS5 SGDID:S000005422,5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, histidine, and tryptophan biosynthesis; one of a five related enzymes, which are active as heteromultimeric complexes, Chr XV from 212244-213734, Verified ORF YGL146C 6.38 0.95 1 208.165 1 YGL146C YGL146C SGDID:S000003114,Hypothetical protein, Chr VII from 229691-228756, reverse complement, Uncharacterized ORF YER043C 18.57 1.00 256 19272.2745 1 YER043C SAH1 SGDID:S000000845,S-adenosyl-L-homocysteine hydrolase, catabolizes S-adenosyl-L-homocysteine which is formed after donation of the activated methyl group of S-adenosyl-L-methionine (AdoMet) to an acceptor, Chr V from 237118-235769, reverse complement, Verified ORF YMR054W 25.286 0.83 6 275.3303 1 YMR054W STV1 SGDID:S000004658,Subunit of vacuolar-ATPase V0 domain, one of two isoforms (Stv1p and Vph1p); Stv1p is located in V-ATPase complexes of the Golgi and endosomes while Vph1p is located in V-ATPase complexes of the vacuole, Chr XIII from 383302-385974, Verified ORF YDL014W 10.11 1.00 190 26272.8603 1 YDL014W NOP1 SGDID:S000002172,Nucleolar protein, component of the small subunit processome complex, which is required for processing of pre-18S rRNA; has similarity to mammalian fibrillarin, Chr IV from 427361-428344, Verified ORF YGL026C 31.31 1.00 172 7679.8067 1 YGL026C TRP5 SGDID:S000002994,Tryptophan synthase involved in tryptophan biosynthesis, regulated by the general control system of amino acid biosynthesis, Chr VII from 448540-446417, reverse complement, Verified ORF YCL064C 13.049 1.00 7 749.9386 1 YCL064C CHA1 SGDID:S000000569,Catabolic L-serine (L-threonine) deaminase, catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine, Chr III from 16880-15798, reverse complement, Verified ORF YDR264C 24.617 1.00 6 340.7383 1 YDR264C AKR1 SGDID:S000002672,Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats, Chr IV from 998319-996025, reverse complement, Verified ORF YDR493W 5.17 0.88 2 475.9124 1 YDR493W YDR493W SGDID:S000002901,The authentic, non-tagged protein was localized to the mitochondria, Chr IV from 1436209-1436580, Uncharacterized ORF YMR231W 42.06 1.00 5 166.1902 1 YMR231W PEP5 SGDID:S000004844,Peripheral vacuolar membrane protein required for protein trafficking and vacuole biogenesis; forms complex with Pep3p that promotes vesicular docking\fusion reactions in conjunction with SNARE proteins, also interacts with Pep7p, Chr XIII from 733544-736633, Verified ORF YGL022W 21.59 1.00 16 1036.0298 1 YGL022W STT3 SGDID:S000002990,Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; forms a subcomplex with Ost3p and Ost4p and is directly involved in catalysis, Chr VII from 452409-454565, Verified ORF YLR192C 11.25 1.00 47 5840.5029 1 YLR192C HCR1 SGDID:S000004182,Dual function protein involved in translation initiation as a substoichiometric component of eukaryotic translation initiation factor 3 (eIF3) and required for processing of 20S pre-rRNA; binds to eIF3 subunits Rpg1p and Prt1p and 18S rRNA, Chr XII from 539591-538794, reverse complement, Verified ORF YOR265W 8.37 1.00 9 1503.2179 1 YOR265W RBL2 SGDID:S000005791,Protein involved in microtubule morphogenesis, required for protection from excess free beta-tubulin; proposed to be involved the folding of beta-tubulin, Chr XV from 820453-820773, Verified ORF YBR143C 24.525 1.00 38 2166.1049 1 YBR143C SUP45 SGDID:S000000347,Polypeptide release factor involved in translation termination; mutant form acts as a recessive omnipotent suppressor, Chr II from 532176-530863, reverse complement, Verified ORF YOR326W 75.55 1.00 20 370.0841 1 YOR326W MYO2 SGDID:S000005853,One of two type V myosins, involved in polarized distribution of mitochondria; required for mitochondrion and vacuole inheritance and nuclear spindle orientation; moves multiple cargo; reversibly phosphorylated in vivo, Chr XV from 925718-930442, Verified ORF YJR064W 27.169 1.00 14 720.376 1 YJR064W CCT5 SGDID:S000003825,Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo, Chr X from 555829-557517, Verified ORF YOR038C 35.32 0.80 6 189.9876 1 YOR038C HIR2 SGDID:S000005564,Non-essential transcriptional corepressor involved in the cell cycle-regulated transcription of histone H2A, H2B, H3, and H4 genes; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p, Chr XV from 405388-402761, reverse complement, Verified ORF YIL103W 17.35 0.99 7 558.3913 1 YIL103W DPH1 SGDID:S000001365,Protein required, along with Dph2p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph2p and Kti11p, Chr IX from 171748-173025, Verified ORF YLR426W 11.84 0.96 9 1020.1568 1 YLR426W YLR426W SGDID:S000004418,Putative protein of unknown function localized to the mitochondria; proposed to be involved in resistance to mechlorethamine and streptozotocin, Chr XII from 987059-987138,987210-988110, Uncharacterized ORF YOR276W 4.23 0.99 4 1308.7591 1 YOR276W CAF20 SGDID:S000005802,Phosphoprotein of the mRNA cap-binding complex involved in translational control, repressor of cap-dependent translation initiation, competes with eIF4G for binding to eIF4E, Chr XV from 841332-841817, Verified ORF YGR261C 35.456 0.97 12 458.9529 1 YGR261C APL6 SGDID:S000003493,Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline phosphatase to the vacuole via the alternate pathway; exists in both cytosolic and peripherally associated membrane-bound pools, Chr VII from 1016756-1014327, reverse complement, Verified ORF YGR253C 11.38 1.00 9 1105.6181 1 YGR253C PUP2 SGDID:S000003485,Alpha subunit of the 20S proteasome involved in ubiquitin-dependent catabolism; human homolog is subunit zeta, Chr VII from 999145-998363, reverse complement, Verified ORF YDR055W 10.67 1.00 9 1179.1878 1 YDR055W PST1 SGDID:S000002462,Cell wall protein that contains a putative GPI-attachment site; secreted by regenerating protoplasts; up-regulated by activation of the cell integrity pathway, as mediated by Rlm1p; upregulated by cell wall damage via disruption of FKS1, Chr IV from 563525-564859, Verified ORF YDL190C 38.37 1.00 6 218.6071 1 YDL190C UFD2 SGDID:S000002349,Ubiquitin chain assembly factor (E4) that cooperates with a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), and a ubiquitin protein ligase (E3) to conjugate ubiquitin to substrates; also functions as an E3, Chr IV from 121593-118708, reverse complement, Verified ORF YLR335W 35.13 1.00 20 795.8967 1 YLR335W NUP2 SGDID:S000004327,Protein involved in nucleocytoplasmic transport, binds to either the nucleoplasmic or cytoplasmic faces of the nuclear pore complex depending on Ran-GTP levels; also has a role in chromatin organization, Chr XII from 797430-799592, Verified ORF YMR190C 56.84 0.69 1 16.9707 1 YMR190C SGS1 SGDID:S000004802,Nucleolar DNA helicase of the RecQ family involved in maintenance of genome integrity, regulates chromosome synapsis and meiotic crossing over; has similarity to human BLM and WRN helicases implicated in Bloom and Werner syndromes, Chr XIII from 645257-640914, reverse complement, Verified ORF YJR017C 10.948 1.00 13 1660.0205 1 YJR017C ESS1 SGDID:S000003778,Peptidylprolyl-cis\trans-isomerase (PPIase) specific for phosphorylated serine and threonine residues N-terminal to proline; regulates phosphorylation of the RNA polymerase II large subunit (Rpo21p) C-terminal domain, Chr X from 466948-466436, reverse complement, Verified ORF YKR048C 14.339 1.00 54 5264.7749 1 YKR048C NAP1 SGDID:S000001756,Protein that interacts with mitotic cyclin Clb2p; required for the regulation of microtubule dynamics during mitosis; controls bud morphogenesis; involved in the transport of H2A and H2B histones to the nucleus, Chr XI from 526282-525029, reverse complement, Verified ORF YDR129C 32.34 1.00 57 2463.9946 1 YDR129C SAC6 SGDID:S000002536,Fimbrin, actin-bundling protein; cooperates with Scp1p (calponin\transgelin) in the organization and maintenance of the actin cytoskeleton, Chr IV from 715376-715356,715244-713337, reverse complement, Verified ORF YMR099C 15.65 1.00 45 4019.7873 1 YMR099C YMR099C SGDID:S000004705,Hypothetical protein, Chr XIII from 464826-463933, reverse complement, Uncharacterized ORF YLL026W 43.09 1.00 77 2498.1536 1 YLL026W HSP104 SGDID:S000003949,Heat shock protein that cooperates with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refold and reactivate previously denatured, aggregated proteins; responsive to stresses including: heat, ethanol, and sodium arsenite; involved in [PSI+] propagation, Chr XII from 88622-91348, Verified ORF YMR027W 26.263 1.00 26 1383.9931 1 YMR027W YMR027W SGDID:S000004629,High level expression reduced Ty3 Transposition, Chr XIII from 325876-327288, Uncharacterized ORF YGR135W 12.55 1.00 17 1893.6953 1 YGR135W PRE9 SGDID:S000003367,20S proteasome beta-type subunit; the only nonessential 20S subunit, Chr VII from 761397-762173, Verified ORF YHR099W 155.96 1.00 27 242.0223 1 YHR099W TRA1 SGDID:S000001141,Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation, Chr VIII from 302764-313998, Verified ORF YMR283C 18.15 0.98 18 1358.7102 1 YMR283C RIT1 SGDID:S000004896,2'-O-ribosyl phosphate transferase, modifies the initiator methionine tRNA at position 64 to distinguish it from elongator methionine tRNA, Chr XIII from 836866-835325, reverse complement, Verified ORF YER083C 7.83 1.00 5 892.7156 1 YER083C GET2 SGDID:S000000885,Subunit of the GET complex; required for meiotic nuclear division and for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion; may be involved in cell wall function, Chr V from 327027-326170, reverse complement, Verified ORF YLR360W 14.508 0.69 8 531.9079 1 YLR360W VPS38 SGDID:S000004352,Part of a Vps34p phosphatidylinositol 3-kinase complex that functions in carboxypeptidase Y (CPY) sorting; binds Vps30p and Vps34p to promote production of phosphatidylinositol 3-phosphate (PtdIns3P) which stimulates kinase activity, Chr XII from 846102-847421, Verified ORF YBR137W 7.02 0.95 1 189.187 1 YBR137W YBR137W SGDID:S000000341,Protein of unknown function; localized to the cytoplasm; binds to Replication Protein A (RPA); YBR137W is not an essential gene, Chr II from 513038-513577, Uncharacterized ORF YBR011C 22.33 1.00 340 21286.0514 1 YBR011C IPP1 SGDID:S000000215,Cytoplasmic inorganic pyrophosphatase (PPase), catalyzes the rapid exchange of oxygens from Pi with water, highly expressed and essential for viability, active-site residues show identity to those from E. coli PPase, Chr II from 257973-257110, reverse complement, Verified ORF YJR062C 23.878 0.99 6 347.771 1 YJR062C NTA1 SGDID:S000003823,Amidase, removes the amide group from N-terminal asparagine and glutamine residues to generate proteins with N-terminal aspartate and glutamate residues that are targets of ubiquitin-mediated degradation, Chr X from 554764-553391, reverse complement, Verified ORF YKL212W 30.328 1.00 26 1198.4902 1 YKL212W SAC1 SGDID:S000001695,Lipid phosphoinositide phosphatase of the ER and Golgi, involved in protein trafficking and secretion, Chr XI from 34544-36415, Verified ORF YNL281W 8.45 0.98 2 324.2681 1 YNL281W HCH1 SGDID:S000005225,Heat shock protein regulator that binds to Hsp90p and may stimulate ATPase activity; originally identified as a high-copy number suppressor of a HSP90 loss-of-function mutation; GFP-fusion protein localizes to the cytoplasm and nucleus, Chr XIV from 108467-108928, Verified ORF YPL082C 76.405 1.00 13 237.8627 1 YPL082C MOT1 SGDID:S000006003,Essential abundant protein involved in regulation of transcription, removes Spt15p (TBP) from DNA via its C-terminal ATPase activity, forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity, Chr XVI from 404080-398477, reverse complement, Verified ORF YDR063W 4.26 0.69 1 226.4354 1 YDR063W YDR063W SGDID:S000002470,Hypothetical protein, Chr IV from 578661-579110, Uncharacterized ORF YLR247C 70.178 1.00 5 99.6033 1 YLR247C YLR247C SGDID:S000004237,Hypothetical protein, Chr XII from 633356-628686, reverse complement, Uncharacterized ORF YHL030W 82.09 1.00 11 187.33 1 YHL030W ECM29 SGDID:S000001022,Major component of the proteasome; tethers the proteasome core particle to the regulatory particle, and enhances the stability of the proteasome, Chr VIII from 40082-45688, Verified ORF YLR419W 74.017 1.00 18 339.9741 1 YLR419W YLR419W SGDID:S000004411,Hypothetical protein, Chr XII from 958425-962732, Uncharacterized ORF YOR142W 14.17 1.00 33 3255.7346 1 YOR142W LSC1 SGDID:S000005668,Alpha subunit of succinyl-CoA ligase, which is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate, Chr XV from 593058-594047, Verified ORF YLR430W 100.657 1.00 17 236.1075 1 YLR430W SEN1 SGDID:S000004422,Nuclear protein, putative helicase required for processing of tRNAs, rRNAs, and small nuclear RNAs; potential Cdc28p substrate, Chr XII from 993431-1000126, Verified ORF YDR304C 10.078 1.00 51 7074.5811 1 YDR304C CPR5 SGDID:S000002712,Peptidyl-prolyl cis-trans isomerase (cyclophilin) of the endoplasmic reticulum, catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; transcriptionally induced in response to unfolded proteins in the ER, Chr IV from 1072553-1071876, reverse complement, Verified ORF YHR001W-A 2.05 0.77 2 1050.1994 1 YHR001W-A QCR10 SGDID:S000003529,Subunit of the ubiqunol-cytochrome c oxidoreductase complex, involved in aerobic respiration, Chr VIII from 107821-107826,107890-108117, Verified ORF YML051W 14.098 0.82 1 81.3132 1 YML051W GAL80 SGDID:S000004515,Transcriptional regulator involved in the repression of GAL genes in the absence of galactose; inhibits transcriptional activation by Gal4p; inhibition relieved by Gal3p or Gal1p binding, Chr XIII from 171594-172901, Verified ORF YCL014W 84.214 1.00 16 265.6076 1 YCL014W BUD3 SGDID:S000000520,Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding, Chr III from 96281-101191, Verified ORF YDR422C 28.36 0.65 2 64.0828 1 YDR422C SIP1 SGDID:S000002830,Alternate beta-subunit of the Snf1p kinase complex, may confer substrate specificity; vacuolar protein containing KIS (Kinase-Interacting Sequence) and ASC (Association with Snf1 kinase Complex) domains involved in protein interactions, Chr IV from 1317765-1315318, reverse complement, Verified ORF YIL014W 22.495 0.84 3 156.6099 1 YIL014W MNT3 SGDID:S000001276,Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation, Chr IX from 326101-327993, Verified ORF YBR057C 11.88 0.93 2 218.8776 1 YBR057C MUM2 SGDID:S000000261,Cytoplasmic protein essential for meiotic DNA replication and sporulation; interacts with Orc2p, which is a component of the origin recognition complex, Chr II from 353291-352191, reverse complement, Verified ORF YOR153W 40.02 1.00 61 2130.8734 1 YOR153W PDR5 SGDID:S000005679,Short-lived membrane ABC (ATP-binding cassette) transporter, actively exports various drugs, expression regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth, Chr XV from 619841-624376, Verified ORF YPL032C 21.92 0.93 13 771.0644 1 YPL032C SVL3 SGDID:S000005953,Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck, Chr XVI from 491362-488885, reverse complement, Verified ORF YDL051W 13.37 1.00 11 1150.181 1 YDL051W LHP1 SGDID:S000002209,RNA binding protein required for maturation of tRNA and snRNA precursors; acts as a molecular chaperone for RNAs transcribed by polymerase III; homologous to human La (SS-B) autoantigen, Chr IV from 363952-364779, Verified ORF YLL040C 136.978 1.00 19 193.9133 1 YLL040C VPS13 SGDID:S000003963,Protein of unknown function; heterooligomeric or homooligomeric complex; peripherally associated with membranes; homologous to human COH1; involved in sporulation, vacuolar protein sorting and protein-Golgi retention, Chr XII from 63644-54210, reverse complement, Verified ORF YEL071W 23.102 1.00 60 3630.8355 1 YEL071W DLD3 SGDID:S000000797,D-lactate dehydrogenase, part of the retrograde regulon which consists of genes whose expression is stimulated by damage to mitochondria and reduced in cells grown with glutamate as the sole nitrogen source, located in the cytoplasm, Chr V from 16355-17845, Verified ORF YLR389C 47.256 0.95 2 56.2084 1 YLR389C STE23 SGDID:S000004381,Metalloprotease involved, with homolog Axl1p, in N-terminal processing of pro-a-factor to the mature form; member of the insulin-degrading enzyme family, Chr XII from 902660-899577, reverse complement, Verified ORF YGR157W 26.13 0.92 4 196.8853 1 YGR157W CHO2 SGDID:S000003389,Phosphatidylethanolamine methyltransferase (PEMT), catalyzes the first step in the conversion of phosphatidylethanolamine to phosphatidylcholine during the methylation pathway of phosphatidylcholine biosynthesis, Chr VII from 802445-805054, Verified ORF YJL072C 8.25 0.89 8 1206.51 1 YJL072C PSF2 SGDID:S000003608,Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery, Chr X from 305779-305138, reverse complement, Verified ORF YNL263C 10.9 0.89 1 114.148 1 YNL263C YIF1 SGDID:S000005207,Integral membrane protein required for the fusion of ER-derived COPII transport vesicles with the Golgi; interacts with Yip1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles, Chr XIV from 147841-146897, reverse complement, Verified ORF YOR061W 13.59 0.99 6 611.0431 1 YOR061W CKA2 SGDID:S000005587,Alpha' catalytic subunit of casein kinase 2, a Ser\Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases, Chr XV from 441536-442555, Verified ORF YPL154C 14.55 1.00 58 5572.7545 1 YPL154C PEP4 SGDID:S000006075,Vacuolar aspartyl protease (proteinase A), required for the posttranslational precursor maturation of vacuolar proteinases; synthesized as a zymogen, self-activates, Chr XVI from 260930-259713, reverse complement, Verified ORF YDR033W 4.68 1.00 51 15234.5361 1 YDR033W MRH1 SGDID:S000002440,Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; has similarity to Hsp30p and Yro2p, which are induced during heat shock, Chr IV from 508144-509106, Verified ORF YPR154W 5.91 0.96 2 454.1702 1 YPR154W PIN3 SGDID:S000006358,Protein that induces appearance of [PIN+] prion when overproduced, Chr XVI from 834561-835208, Verified ORF YDR303C 34.22 1.00 6 245.1185 1 YDR303C RSC3 SGDID:S000002711,One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; essential gene required for regulation of ribosomal protein genes and the cell wall\stress response; highly similar to Rsc30p, Chr IV from 1071382-1068725, reverse complement, Verified ORF YKL148C 23.909 1.00 7 409.2998 1 YKL148C SDH1 SGDID:S000001631,Flavoprotein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone, Chr XI from 171134-169212, reverse complement, Verified ORF YNL241C 28.66 1.00 76 3707.1684 1 YNL241C ZWF1 SGDID:S000005185,Glucose-6-phosphate dehydrogenase (G6PD), catalyzes the first step of the pentose phosphate pathway; involved in adapting to oxidatve stress; homolog of the human G6PD which is deficient in patients with hemolytic anemia, Chr XIV from 197944-196427, reverse complement, Verified ORF YDR038C 36.19 1.00 17 656.6973 3 YDR039C,YDR038C,YDR040C ENA5 SGDID:S000002445,Protein with similarity to P-type ATPase sodium pumps, Chr IV from 530694-527419, reverse complement, Verified ORF YGR238C 34.92 0.72 3 86.4737 1 YGR238C KEL2 SGDID:S000003470,Protein that functions in a complex with Kel1p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate, Chr VII from 968692-966044, reverse complement, Verified ORF YEL011W 29.64 0.75 4 141.4972 1 YEL011W GLC3 SGDID:S000000737,Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern, Chr V from 133120-135234, Verified ORF YJL217W 11.06 0.98 10 1238.7277 1 YJL217W YJL217W SGDID:S000003753,Cytoplasmic protein of unknown function; expression induced by calcium shortage and via the copper sensing transciption factor Mac1p during conditons of copper deficiency; mRNA is cell cycle regulated, peaking in G1 phase, Chr X from 23133-23729, Uncharacterized ORF YML103C 54.658 1.00 6 153.4625 1 YML103C NUP188 SGDID:S000004571,Subunit of the nuclear pore complex (NPC), involved in the structural organization of the complex and of the nuclear envelope, also involved in nuclear envelope permeability, interacts with Pom152p and Nic96p, Chr XIII from 67549-62582, reverse complement, Verified ORF YIL051C 7.26 1.00 189 36394.0255 1 YIL051C MMF1 SGDID:S000001313,Mitochondrial protein involved in maintenance of the mitochondrial genome, Chr IX from 258279-257842, reverse complement, Verified ORF YLR397C 35.97 1.00 10 388.6551 1 YLR397C AFG2 SGDID:S000004389,ATPase of the CDC48\PAS1\SEC18 (AAA) family, forms a hexameric complex; may be involved in degradation of aberrant mRNAs, Chr XII from 914892-912550, reverse complement, Verified ORF YDL140C 58.099 1.00 31 745.9297 1 YDL140C RPO21 SGDID:S000002299,RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime, Chr IV from 210562-205361, reverse complement, Verified ORF YPL129W 9.33 1.00 10 1498.3844 1 YPL129W TAF14 SGDID:S000006050,Subunit (30 kDa) of TFIID, TFIIF, and SWI\SNF complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, contains a YEATS domain, Chr XVI from 305297-305305,305411-306136, Verified ORF YKL058W 6.44 0.99 17 3653.4499 1 YKL058W TOA2 SGDID:S000001541,TFIIA small subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; homologous to smallest subunit of human and Drosophila TFIIA, Chr XI from 329810-330178, Verified ORF YOR204W 26.74 1.00 143 7476.1765 1 YOR204W DED1 SGDID:S000005730,ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all yeast mRNAs; mutations in human DEAD-box DBY are a frequent cause of male infertility, Chr XV from 722912-724726, Verified ORF YOR367W 14.478 0.99 6 573.5651 1 YOR367W SCP1 SGDID:S000005894,Component of yeast cortical actin cytoskeleton, binds and cross links actin filaments; originally identified by its homology to calponin (contains a calponin-like repeat) but the Scp1p domain structure is more similar to transgelin, Chr XV from 1026005-1026607, Verified ORF YOL059W 13.547 1.00 40 4127.8297 1 YOL059W GPD2 SGDID:S000005420,NAD-dependent glycerol 3-phosphate dehydrogenase, homolog of Gpd1p, expression is controlled by an oxygen-independent signaling pathway required to regulate metabolism under anoxic conditions; located in cytosol and mitochondria, Chr XV from 217126-218448, Verified ORF YOR165W 38.924 0.97 6 209.0308 1 YOR165W SEY1 SGDID:S000005691,Protein of unknown function, contains two predicted GTP-binding motifs GXXXXGKS and DXXG near the N-terminus, homolog of the Arabidopsis gene RHD3 (Root Hair Defective), Chr XV from 644567-646897, Verified ORF YJR088C 11.87 0.99 2 233.195 1 YJR088C YJR088C SGDID:S000003848,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum, Chr X from 587288-586410, reverse complement, Uncharacterized ORF YJL089W 23.83 0.67 1 39.3057 1 YJL089W SIP4 SGDID:S000003625,C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus, Chr X from 265843-268332, Verified ORF YCR014C 27.99 1.00 5 249.7307 1 YCR014C POL4 SGDID:S000000607,DNA polymerase IV, undergoes pair-wise interactions with Dnl4p-Lif1p and Rad27p to mediate repair of DNA double-strand breaks by non-homologous end joining (NHEJ); homologous to mammalian DNA polymerase beta, Chr III from 140931-139183, reverse complement, Verified ORF YJR109C 44.98 1.00 55 1709.4175 1 YJR109C CPA2 SGDID:S000003870,Large subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor, Chr X from 632857-629501, reverse complement, Verified ORF YOR022C 30.758 0.97 8 352.7025 1 YOR022C YOR022C SGDID:S000005548,Hypothetical protein, Chr XV from 375857-373710, reverse complement, Uncharacterized ORF YNL176C 11.56 0.99 16 1915.5886 1 YNL176C YNL176C SGDID:S000005120,Hypothetical protein, Chr XIV from 306982-305072, reverse complement, Uncharacterized ORF YKL068W 16.08 0.73 1 63.466 1 YKL068W NUP100 SGDID:S000001551,Subunit of the nuclear pore complex (NPC) that is localized to both sides of the pore; contains a repetitive GLFG motif that interacts with mRNA export factor Mex67p and with karyopherin Kap95p; homologous to Nup116p, Chr XI from 309843-312722, Verified ORF YHR020W 33.96 1.00 214 8809.4948 1 YHR020W YHR020W SGDID:S000001062,Putative protein of unknown function, has similarity to proline-tRNA ligase; YHR020W is an essential gene, Chr VIII from 143989-146055, Uncharacterized ORF YDR454C 11.46 1.00 112 13662.7561 1 YDR454C GUK1 SGDID:S000002862,Guanylate kinase, converts GMP to GDP; required for growth and mannose outer chain elongation of cell wall N-linked glycoproteins, Chr IV from 1366819-1366256, reverse complement, Verified ORF YMR235C 21.407 1.00 27 1763.2458 1 YMR235C RNA1 SGDID:S000004848,GTPase activating protein (GAP) for Gsp1p, involved in nuclear transport, Chr XIII from 742734-741511, reverse complement, Verified ORF YGR123C 17.03 1.00 7 574.63 1 YGR123C PPT1 SGDID:S000003355,Protein serine\threonine phosphatase with similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth, Chr VII from 738208-736667, reverse complement, Verified ORF YGL099W 33.17 1.00 32 1348.6815 1 YGL099W LSG1 SGDID:S000003067,Putative GTPase involved in 60S ribosomal subunit biogenesis; required for the release of Nmd3p from 60S subunits in the cytoplasm, Chr VII from 314634-316556, Verified ORF YJL187C 32.355 0.99 6 256.6551 1 YJL187C SWE1 SGDID:S000003723,Protein kinase that regulates the G2\M transition by inhibition of Cdc28p kinase activity; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate, Chr X from 79261-76802, reverse complement, Verified ORF YBL050W 16.128 1.00 25 2167.0274 1 YBL050W SEC17 SGDID:S000000146,Peripheral membrane protein required for vesicular transport between ER and Golgi and for the 'priming' step in homotypic vacuole fusion, part of the cis-SNARE complex; has similarity to alpha-SNAP, Chr II from 125128-125157,125274-126122, Verified ORF YBR269C 9.48 0.99 4 583.9716 1 YBR269C YBR269C SGDID:S000000473,The authentic, non-tagged protein was localized to the mitochondria, Chr II from 742571-742155, reverse complement, Uncharacterized ORF YJR039W 45.71 0.96 5 146.8029 1 YJR039W YJR039W SGDID:S000003800,Hypothetical protein, Chr X from 503851-507216, Uncharacterized ORF YDR408C 7.08 0.99 1 195.482 1 YDR408C ADE8 SGDID:S000002816,Phosphoribosyl-glycinamide transformylase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway, Chr IV from 1288851-1288207, reverse complement, Verified ORF YDL019C 54.138 0.86 15 333.1136 1 YDL019C OSH2 SGDID:S000002177,Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability, Chr IV from 421511-417660, reverse complement, Verified ORF YJR059W 27.64 0.96 1 48.5554 1 YJR059W PTK2 SGDID:S000003820,Putative serine\threonine protein kinase involved in regulation of ion transport across plasma membrane; enhances spermine uptake, Chr X from 545702-548158, Verified ORF YJL148W 11.57 0.95 2 229.5752 1 YJL148W RPA34 SGDID:S000003684,RNA polymerase I subunit A34.5, Chr X from 140356-141057, Verified ORF YOR095C 16.2 1.00 24 2071.1003 1 YOR095C RKI1 SGDID:S000005621,Ribose-5-phosphate ketol-isomerase, catalyzes the interconversion of ribose 5-phosphate and ribulose 5-phosphate in the pentose phosphate pathway; participates in pyridoxine biosynthesis, Chr XV from 504329-503553, reverse complement, Verified ORF YNL258C 32.63 0.71 5 152.0954 1 YNL258C DSL1 SGDID:S000005202,Endoplasmic reticulum (ER)-localized peripheral membrane protein required for Golgi-to-ER retrograde traffic; component of the ER target site that interacts with coatomer, the major component of the COPI vesicle protein coat, Chr XIV from 160374-158110, reverse complement, Verified ORF YPR159W 16.95 1.00 6 494.8646 1 YPR159W KRE6 SGDID:S000006363,Protein required for beta-1,6 glucan biosynthesis; putative beta-glucan synthase; appears functionally redundant with Skn1p, Chr XVI from 857579-859741, Verified ORF YMR198W 36.27 0.89 5 171.521 1 YMR198W CIK1 SGDID:S000004811,Kinesin-associated protein required for both karyogamy and mitotic spindle organization, interacts stably and specifically with Kar3p and may function to target this kinesin to a specific cellular role; has similarity to Vik1p, Chr XIII from 659744-661528, Verified ORF YKL112W 23.47 1.00 4 238.2603 1 YKL112W ABF1 SGDID:S000001595,DNA binding protein with possible chromatin-reorganizing activity involved in transcriptional activation, gene silencing, and DNA replication and repair, Chr XI from 226214-228409, Verified ORF YML086C 25.46 1.00 13 713.8218 1 YML086C ALO1 SGDID:S000004551,D-Arabinono-1,4-lactone oxidase, catalyzes the final step in biosynthesis of D-erythroascorbic acid, which is protective against oxidative stress, Chr XIII from 97371-95791, reverse complement, Verified ORF YHR089C 6.71 1.00 31 6458.6847 1 YHR089C GAR1 SGDID:S000001131,Protein component of the H\ACA snoRNP pseudouridylase complex, involved in the modification and cleavage of the 18S pre-rRNA, Chr VIII from 283300-282683, reverse complement, Verified ORF YMR116C 14.777 1.00 393 37180.1544 1 YMR116C ASC1 SGDID:S000004722,WD repeat protein (G-beta like protein) involved in translation regulation; required for repression of Gcn4p activity in the absence of amino-acid starvation; core component of the ribosome; ortholog of mammalian RACK1, Chr XIII from 500687-500151,499877-499455, reverse complement, Verified ORF YKR095W-A 5.47 0.90 7 1610.1195 1 YKR095W-A YKR095W-A SGDID:S000028512,Protein of unknown function, conserved in Ashbya gossypii, Chr XI from 625506-625543,625619-625847, Uncharacterized ORF YAL044C 5.09 1.00 53 14556.7022 1 YAL044C GCV3 SGDID:S000000042,H subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm, Chr I from 58463-57951, reverse complement, Verified ORF YOR122C 3.6 1.00 19 7378.2949 1 YOR122C PFY1 SGDID:S000005648,Profilin, actin- and phosphatidylinositol 4,5-bisphosphate-binding protein, plays a role in cytoskeleton organization, required for normal timing of actin polymerization in response to thermal stress; localizes to plasma membrane and cytosol, Chr XV from 552888-552876,552666-552299, reverse complement, Verified ORF YKL197C 39.98 0.97 1 33.9182 1 YKL197C PEX1 SGDID:S000001680,AAA-family ATPase peroxin required for peroxisome biogenesis, contains two 230 amino acid ATP-binding AAA cassettes, upregulated in anaerobiosis; Pex1p and Pex6p interact via their N-terminal AAA-cassettes, Chr XI from 73870-70739, reverse complement, Verified ORF YCL054W 34.07 1.00 5 205.1647 1 YCL054W SPB1 SGDID:S000000559,AdoMet-dependent methyltransferase involved in rRNA processing and 60S ribosomal subunit maturation; methylates G2922 in the putative tRNA docking site of the large subunit rRNA and in the absence of snR52, U2921; suppressor of PAB1 mutants, Chr III from 31449-33974, Verified ORF YNL268W 12.95 0.99 2 213.7471 1 YNL268W LYP1 SGDID:S000005212,Lysine permease; one of three amino acid permeases (Alp1p, Can1p, Lyp1p) responsible for uptake of cationic amino acids, Chr XIV from 138551-140386, Verified ORF YDL029W 17.41 1.00 33 2649.8426 1 YDL029W ARP2 SGDID:S000002187,Essential component of the Arp2\3 complex, which is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity, Chr IV from 399337-399358,399482-400635, Verified ORF YDR403W 22.208 0.95 5 299.0123 1 YDR403W DIT1 SGDID:S000002811,Sporulation-specific enzyme required for spore wall maturation, involved in the production of a soluble LL-dityrosine-containing precursor of the spore wall; transcripts accumulate at the time of prospore enclosure, Chr IV from 1274594-1276204, Verified ORF YOL121C 7.92 1.00 353 62309.5244 2 YNL302C,YOL121C RPS19A SGDID:S000005481,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps19Bp and has similarity to rat S19 ribosomal protein, Chr XV from 92850-92831,92440-92026, reverse complement, Verified ORF YLR420W 13.65 1.00 27 2765.2603 1 YLR420W URA4 SGDID:S000004412,Dihydroorotase, catalyzes the third enzymatic step in the de novo biosynthesis of pyrimidines, converting carbamoyl-L-aspartate into dihydroorotate, Chr XII from 963782-964876, Verified ORF YNL151C 11.12 0.99 1 124.4615 1 YNL151C RPC31 SGDID:S000005095,RNA polymerase III subunit C31; contains HMG-like C-terminal domain, Chr XIV from 348523-347768, reverse complement, Verified ORF YDL225W 29.33 0.95 3 135.8431 1 YDL225W SHS1 SGDID:S000002384,One of five related septins (Cdc3p, Cdc10p, Cdc11p, Cdc12p, Shs1p) that form a cortical filamentous collar at the mother-bud neck which is necessary for normal morphogenesis and cytokinesis, Chr IV from 52446-54101, Verified ORF YBR149W 19.16 1.00 9 656.6771 1 YBR149W ARA1 SGDID:S000000353,Large subunit of NADP+ dependent arabinose dehydrogenase, involved in carbohydrate metabolism; small subunit is unidentified, Chr II from 539981-541015, Verified ORF YCL016C 13.618 0.93 2 190.9433 1 YCL016C DCC1 SGDID:S000000521,Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C, required for sister chromatid cohesion and telomere length maintenance, Chr III from 95763-94621, reverse complement, Verified ORF YPL255W 24.318 0.93 7 374.2467 1 YPL255W BBP1 SGDID:S000006176,Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periphery; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p, Chr XVI from 67725-68882, Verified ORF YNL112W 22.84 1.00 42 2570.7396 1 YNL112W DBP2 SGDID:S000005056,Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated mRNA decay and rRNA processing, Chr XIV from 413641-414913,415916-416283, Verified ORF YCR072C 18.228 0.93 2 142.6523 1 YCR072C RSA4 SGDID:S000000668,WD-repeat protein involved in ribosome biogenesis; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus, Chr III from 242348-240801, reverse complement, Verified ORF YKR093W 13.42 0.91 1 94.7968 1 YKR093W PTR2 SGDID:S000001801,Integral membrane peptide transporter, mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p, Chr XI from 615372-617177, Verified ORF YDR342C 10.45 1.00 21 2809.3633 2 YDR343C,YDR342C HXT7 SGDID:S000002750,High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt6p, expressed at high basal levels relative to other HXTs, expression repressed by high glucose levels, Chr IV from 1155922-1154210, reverse complement, Verified ORF YDR226W 17.14 1.00 163 13294.7966 1 YDR226W ADK1 SGDID:S000002634,Adenylate kinase, required for purine metabolism; localized to the cytoplasm and the mitochondria; lacks cleavable signal sequence, Chr IV from 916482-917150, Verified ORF YHL019C 21.33 0.98 1 64.2303 1 YHL019C APM2 SGDID:S000001011,Protein of unknown function, homologous to the medium chain of mammalian clathrin-associated protein complex; involved in vesicular transport, Chr VIII from 69545-67728, reverse complement, Verified ORF YDR471W 5.9 1.00 241 57104.4487 2 YHR010W,YDR471W RPL27B SGDID:S000002879,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Ap and has similarity to rat L27 ribosomal protein, Chr IV from 1401762-1401792,1402177-1402556, Verified ORF YJL080C 70.767 1.00 199 3931.2186 1 YJL080C SCP160 SGDID:S000003616,Essential RNA-binding G protein effector of mating response pathway, predominantly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins, Chr X from 289143-285475, reverse complement, Verified ORF YOR380W 13.85 0.97 7 685.3697 1 YOR380W RDR1 SGDID:S000005907,Transcriptional repressor involved in the control of multidrug resistance; negatively regulates expression of the PDR5 gene; member of the Gal4p family of zinc cluster proteins, Chr XV from 1051288-1052928, Verified ORF YLR298C 10.26 0.98 3 400.5944 1 YLR298C YHC1 SGDID:S000004289,Component of the U1 snRNP complex required for pre-mRNA splicing; putative ortholog of human U1C protein, which is involved in formation of a complex between U1 snRNP and the pre-mRNA 5' splice site, Chr XII from 725418-724723, reverse complement, Verified ORF YFL044C 9.4 0.99 5 736.177 1 YFL044C OTU1 SGDID:S000001850,Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p; may contribute to regulation of protein degradation by deubiquitylating substrates that have been ubiquitylated by Ufd2p; member of the Ovarian Tumor (OTU) family, Chr VI from 45560-44655, reverse complement, Verified ORF YHR039C 23.98 0.99 7 404.007 1 YHR039C MSC7 SGDID:S000001081,Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids, Chr VIII from 186802-184868, reverse complement, Verified ORF YGR109W-B 66.118 0.99 8 167.4597 1 YGR109W-B YGR109W-B SGDID:S000007347,TyB Gag-Pol protein; proteolytically processed to make the Gag, RT, PR, and IN proteins that are required for retrotransposition, Chr VII from 707614-708463,708465-712258, transposable_element_gene YOR089C 12.52 0.93 2 207.689 1 YOR089C VPS21 SGDID:S000005615,GTPase required for transport during endocytosis and for correct sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog, Chr XV from 490830-490198, reverse complement, Verified ORF YJR117W 18.005 1.00 10 776.4469 1 YJR117W STE24 SGDID:S000003878,Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; contains multiple transmembrane spans, Chr X from 641923-643284, Verified ORF YBR245C 68.99 0.98 10 198.5842 1 YBR245C ISW1 SGDID:S000000449,Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase that forms a complex with Ioc2p and Ioc4p to regulate transcription elongation, and a complex with Ioc3p to repress transcription initiation, Chr II from 711534-708145, reverse complement, Verified ORF YIL009W 23.42 0.96 2 114.6091 1 YIL009W FAA3 SGDID:S000001271,Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, Chr IX from 339341-341425, Verified ORF YOR271C 12.82 0.97 3 317.329 1 YOR271C YOR271C SGDID:S000005797,Hypothetical protein, Chr XV from 832041-831058, reverse complement, Uncharacterized ORF YIL126W 63.988 0.97 12 254.3076 1 YIL126W STH1 SGDID:S000001388,ATPase component of the ATP-dependent RSC chromatin remodeling complex required for kinetochore function in chromosome segregation; required for expression of early meiotic genes; essential helicase-related protein homologous to Snf2p, Chr IX from 117992-122071, Verified ORF YLR048W 6.72 1.00 207 43063.1688 1 YLR048W RPS0B SGDID:S000004038,Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Ap; required for maturation of 18S rRNA along with Rps0Ap; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal, Chr XII from 242233-242322,242682-243350, Verified ORF YMR196W 53.066 0.95 3 75.0815 1 YMR196W YMR196W SGDID:S000004809,Hypothetical protein, Chr XIII from 655075-658341, Uncharacterized ORF YOR219C 37.6 1.00 4 148.7226 1 YOR219C STE13 SGDID:S000005745,Dipeptidyl aminopeptidase, Golgi integral membrane protein that cleaves on the carboxyl side of repeating -X-Ala- sequences, required for maturation of alpha factor, transcription is induced by a-factor, Chr XV from 755010-752215, reverse complement, Verified ORF YDR166C 43.63 0.87 5 139.3827 1 YDR166C SEC5 SGDID:S000002573,Essential 107kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis, Chr IV from 789218-786303, reverse complement, Verified ORF YLR299W 27.297 0.85 1 43.532 1 YLR299W ECM38 SGDID:S000004290,Gamma-glutamyltranspeptidase, major glutathione-degrading enzyme; expression induced mainly by nitrogen starvation, Chr XII from 726071-728053, Verified ORF YDR214W 17.37 0.93 4 299.3974 1 YDR214W AHA1 SGDID:S000002622,Co-chaperone that binds to Hsp82p and activates its ATPase activity; similar to Hch1p; expression is regulated by stresses such as heat shock, Chr IV from 892872-893924, Verified ORF YOR195W 55.747 0.77 7 135.1674 1 YOR195W SLK19 SGDID:S000005721,Kinetochore-associated protein required for normal segregation of chromosomes in meiosis and mitosis; component of the FEAR regulatory network, which promotes Cdc14p release from the nucleolus during anaphase; potential Cdc28p substrate, Chr XV from 712867-715332, Verified ORF YER114C 45.295 1.00 6 185.185 1 YER114C BOI2 SGDID:S000000916,Protein implicated in polar growth, functionally redundant with Boi1p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain, Chr V from 393708-390586, reverse complement, Verified ORF YDL194W 20.47 0.87 1 59.4163 1 YDL194W SNF3 SGDID:S000002353,Plasma membrane glucose sensor that regulates glucose transport; has 12 predicted transmembrane segments; long cytoplasmic C-terminal tail is required for low glucose induction of hexose transporter genes HXT2 and HXT4, Chr IV from 111581-114235, Verified ORF YIL076W 10.7 0.95 4 496.4833 1 YIL076W SEC28 SGDID:S000001338,Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein traffic; stabilizes Cop1p, the alpha-COP and the coatomer complex; non-essential for cell growth, Chr IX from 216655-217545, Verified ORF YOR192C-C 3.75 0.81 1 301.9664 1 YOR192C-C YOR192C-C SGDID:S000028857,Identified by expression profiling and mass spectrometry, Chr XV from 704225-703989, reverse complement, Uncharacterized ORF YJL191W 6.6 1.00 177 37491.6231 2 YJL191W,YCR031C RPS14B SGDID:S000003727,Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Ap and similar to E. coli S11 and rat S14 ribosomal proteins, Chr X from 73786-73795,74204-74610, Verified ORF YGR267C 10.94 1.00 13 1661.2345 1 YGR267C FOL2 SGDID:S000003499,GTP-cyclohydrolase I, catalyzes the first step in the folic acid biosynthetic pathway, Chr VII from 1025741-1025010, reverse complement, Verified ORF YIL002C 39.39 0.69 1 24.4888 1 YIL002C INP51 SGDID:S000001264,Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in phosphatidylinositol 4,5-bisphosphate homeostasis and in endocytosis; null mutation confers cold-tolerant growth, Chr IX from 353428-350588, reverse complement, Verified ORF YDR518W 15.43 0.99 3 269.0886 1 YDR518W EUG1 SGDID:S000002926,Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER, Chr IV from 1478600-1480153, Verified ORF YGR185C 18.31 1.00 62 4733.782 1 YGR185C TYS1 SGDID:S000003417,Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase that aminoacylates tRNA(Tyr), required for cytoplasmic protein synthesis, interacts with positions 34 and 35 of the anticodon of tRNATyr, Chr VII from 867525-866341, reverse complement, Verified ORF YKR014C 15.147 0.99 3 274.1162 1 YKR014C YPT52 SGDID:S000001722,GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5; required for vacuolar protein sorting and endocytosis, Chr XI from 465714-465010, reverse complement, Verified ORF YOR178C 30.028 0.89 1 41.4351 1 YOR178C GAC1 SGDID:S000005704,Regulatory subunit for Glc7p type-1 protein phosphatase (PP1), tethers Glc7p to Gsy2p glycogen synthase, binds Hsf1p heat shock transcription factor, required for induction of some HSF-regulated genes under heat shock, Chr XV from 670242-667861, reverse complement, Verified ORF YPL068C 8.67 1.00 36 5804.814 1 YPL068C YPL068C SGDID:S000005989,Hypothetical protein, Chr XVI from 425093-424212, reverse complement, Uncharacterized ORF YLR328W 17.77 1.00 8 629.372 1 YLR328W NMA1 SGDID:S000004320,Nicotinic acid mononucleotide adenylyltransferase, involved in NAD(+) salvage pathway, Chr XII from 784913-786118, Verified ORF YDL176W 24.042 0.89 2 103.5033 1 YDL176W YDL176W SGDID:S000002335,Hypothetical protein, Chr IV from 142098-144224, Uncharacterized ORF YDR487C 8.39 1.00 40 6665.0428 1 YDR487C RIB3 SGDID:S000002895,3,4-dihydroxy-2-butanone-4-phosphate synthase (DHBP synthase), required for riboflavin biosynthesis from ribulose-5-phosphate, also has an unrelated function in mitochondrial respiration, Chr IV from 1428972-1428346, reverse complement, Verified ORF YJR077C 15.26 1.00 32 2931.5705 1 YJR077C MIR1 SGDID:S000003838,Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redundant with Pic2p but more abundant than Pic2 under normal conditions, Chr X from 578105-577170, reverse complement, Verified ORF YNR013C 18.32 1.00 4 305.2385 1 YNR013C PHO91 SGDID:S000005296,Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth, Chr XIV from 651714-649030, reverse complement, Verified ORF YKR018C 31.68 1.00 5 220.6427 1 YKR018C YKR018C SGDID:S000001726,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus, Chr XI from 475543-473366, reverse complement, Uncharacterized ORF YFL005W 14.42 1.00 14 1357.2744 1 YFL005W SEC4 SGDID:S000001889,Secretory vesicle-associated Rab GTPase essential for exocytosis; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane, Chr VI from 130329-130976, Verified ORF YLR342W 56.129 1.00 132 3287.6951 1 YLR342W FKS1 SGDID:S000004334,Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic subunit Gsc2p; binds to regulatory subunit Rho1p; involved in cell wall synthesis and maintenance; localizes to sites of cell wall remodeling, Chr XII from 809997-815627, Verified ORF YGR275W 8.31 0.99 5 832.7393 1 YGR275W RTT102 SGDID:S000003507,Component of both the SWI\SNF and RSC chromatin remodeling complexes, suggested role in chromosome maintenance; possible weak regulator of Ty1 transposition, Chr VII from 1043282-1043755, Verified ORF YFL004W 47.258 1.00 46 1360.7783 1 YFL004W VTC2 SGDID:S000001890,Vacuolar membrane protein involved in vacuolar polyphosphate accumulation; functions as a regulator of vacuolar H+-ATPase activity and vacuolar transporter chaperones; involved in protein localization and non-autophagic vacuolar fusion, Chr VI from 131805-134291, Verified ORF YLR449W 13.2 1.00 33 3494.9818 1 YLR449W FPR4 SGDID:S000004441,Nuclear protein, putative peptidyl-prolyl cis-trans isomerase (PPIase) with similarity to Fpr3p; overproduction suppresses the growth defect resulting from the absence of E3 ubiquitin-protein ligase Tom1p, Chr XII from 1030830-1032008, Verified ORF YNL290W 21.488 1.00 3 195.1776 1 YNL290W RFC3 SGDID:S000005234,Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon, Chr XIV from 86218-87240, Verified ORF YLR277C 31.827 0.98 5 215.2312 1 YLR277C YSH1 SGDID:S000004267,Putative endonuclease, subunit of the mRNA cleavage and polyadenylation specificity complex required for 3' processing of mRNAs, Chr XII from 699497-697158, reverse complement, Verified ORF YHR166C 22 0.93 24 1418.3271 1 YHR166C CDC23 SGDID:S000001209,Subunit of the anaphase-promoting complex\cyclosome (APC\C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase\anaphase transition, Chr VIII from 439052-437172, reverse complement, Verified ORF YDL007W 21.88 1.00 27 1725.1281 1 YDL007W RPT2 SGDID:S000002165,One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for normal peptide hydrolysis by the core 20S particle, Chr IV from 438044-439357, Verified ORF YPL225W 8.93 1.00 7 1095.8509 1 YPL225W YPL225W SGDID:S000006146,Hypothetical protein, Chr XVI from 126006-126446, Uncharacterized ORF YDR358W 25.613 0.94 17 872.2103 1 YDR358W GGA1 SGDID:S000002766,Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi, Chr IV from 1190052-1191725, Verified ORF YFR052W 15.16 1.00 10 922.1587 1 YFR052W RPN12 SGDID:S000001948,Subunit of the 19S regulatory particle of the 26S proteasome lid; synthetically lethal with RPT1, which is an ATPase component of the 19S regulatory particle; physically interacts with Nob1p and Rpn3p, Chr VI from 252492-253316, Verified ORF YGR203W 6.17 0.87 7 1379.8664 1 YGR203W YGR203W SGDID:S000003435,Putative protein with sequence similarity to protein tyrosine phosphatases of the CDC25-like phosphatase family; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus, Chr VII from 905242-905688, Uncharacterized ORF YJR036C 42.747 0.99 11 356.1452 1 YJR036C HUL4 SGDID:S000003797,Protein with similarity to hect domain E3 ubiquitin-protein ligases, not essential for viability, Chr X from 503306-500628, reverse complement, Verified ORF YPL218W 13.478 1.00 72 7468.1315 1 YPL218W SAR1 SGDID:S000006139,GTPase, GTP-binding protein of the ARF family, component of COPII coat of vesicles; required for transport vesicle formation during ER to Golgi protein transport, Chr XVI from 138697-138724,138864-139408, Verified ORF YLL005C 34.67 0.84 3 101.6135 1 YLL005C SPO75 SGDID:S000003928,Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis, Chr XII from 140545-137939, reverse complement, Verified ORF YPR037C 6.78 0.87 6 1076.3306 1 YPR037C ERV2 SGDID:S000006241,Flavin-linked sulfhydryl oxidase localized to the endoplasmic reticulum lumen, involved in disulfide bond formation within the ER, Chr XVI from 647035-646445, reverse complement, Verified ORF YJL145W 16.54 0.97 1 81.9862 1 YJL145W SFH5 SGDID:S000003681,Putative phosphatidylinositol transfer protein (PITP), exhibits phosphatidylinositol- but not phosphatidylcholine-transfer activity, mainly localized to cytosol and microsomes, similar to Sec14p; may be PITP regulator rather than actual PITP, Chr X from 145079-145963, Verified ORF YML008C 16.32 1.00 85 7281.2121 1 YML008C ERG6 SGDID:S000004467,Delta(24)-sterol C-methyltransferase, converts zymosterol to fecosterol in the ergosterol biosynthetic pathway by methylating position C-24; localized to both lipid particles and mitochondrial outer membrane, Chr XIII from 252990-251839, reverse complement, Verified ORF YHR098C 25.05 0.96 4 214.303 1 YHR098C SFB3 SGDID:S000001140,Member of the Sec24p family; forms a complex, with Sec23p, that is involved in sorting of Pma1p into COPII vesicles; peripheral ER membrane protein; potential Cdc28p substrate, Chr VIII from 301937-299148, reverse complement, Verified ORF YLR206W 18.65 1.00 7 524.7157 1 YLR206W ENT2 SGDID:S000004196,Epsin-like protein required for endocytosis and actin patch assembly and functionally redundant with Ent1p; contains clathrin-binding motif at C-terminus, Chr XII from 554580-556421, Verified ORF YOR244W 22.528 0.90 2 111.7004 1 YOR244W ESA1 SGDID:S000005770,Histone acetyltransferase catalytic subunit of the native multisubunit complex (NuA4) that acetylates four conserved internal lysines of histone H4 N-terminal tail; required for cell cycle progression, Chr XV from 792532-793869, Verified ORF YMR314W 12.495 1.00 24 2685.2201 1 YMR314W PRE5 SGDID:S000004931,20S proteasome alpha-type subunit, Chr XIII from 901708-902412, Verified ORF YHR190W 17.32 1.00 10 807.1551 1 YHR190W ERG9 SGDID:S000001233,Farnesyl-diphosphate farnesyl transferase (squalene synthase), joins two farnesyl pyrophosphate moieties to form squalene in the sterol biosynthesis pathway, Chr VIII from 484845-486179, Verified ORF YLR386W 30.198 1.00 4 185.1768 1 YLR386W VAC14 SGDID:S000004378,Protein involved in regulated synthesis of PtdIns(3,5)P(2), in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; activator of Fab1p, Chr XII from 893628-896270, Verified ORF YPR035W 8.97 0.90 6 841.6009 1 YPR035W GLN1 SGDID:S000006239,Glutamine synthetase (GS), synthesizes glutamine from glutamate and ammonia; with Glt1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source and by amino acid limitation, Chr XVI from 642205-643317, Verified ORF YMR015C 20.369 0.86 1 59.0246 1 YMR015C ERG5 SGDID:S000004617,C-22 sterol desaturase, a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs, Chr XIII from 302484-300868, reverse complement, Verified ORF YPR145W 25.159 1.00 144 8001.5482 1 YPR145W ASN1 SGDID:S000006349,Asparagine synthetase, isozyme of Asn2p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway, Chr XVI from 822616-824334, Verified ORF YFL014W 6.94 1.00 4 805.7594 1 YFL014W HSP12 SGDID:S000001880,Plasma membrane localized protein that protects membranes from desiccation; induced by heat shock, oxidative stress, osmostress, stationary phase entry, glucose depletion, oleate and alcohol; regulated by the HOG and Ras-Pka pathways, Chr VI from 107250-107579, Verified ORF YKL078W 34.57 1.00 9 363.9552 1 YKL078W DHR2 SGDID:S000001561,Predominantly nucleolar DEAH-box RNA helicase, required for 18S rRNA synthesis, Chr XI from 288489-290696, Verified ORF YDR155C 8.665 1.00 183 29524.832 1 YDR155C CPR1 SGDID:S000002562,Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds the drug cyclosporin A, Chr IV from 768997-768509, reverse complement, Verified ORF YBR112C 22.199 1.00 15 944.6322 1 YBR112C CYC8 SGDID:S000000316,General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI\SNF and SAGA complexes to promoters, Chr II from 465764-462864, reverse complement, Verified ORF YER133W 11.64 0.99 6 713.4086 1 YER133W GLC7 SGDID:S000000935,Catalytic subunit of type 1 serine\threonine protein phosphatase, involved in many processes including glycogen metabolism, sporulation, and mitosis; interacts with multiple regulatory subunits; predominantly isolated with Sds22p, Chr V from 432491-432667,433193-433954, Verified ORF YNL247W 40.96 1.00 37 1262.8352 1 YNL247W YNL247W SGDID:S000005191,Protein required for cell viability, Chr XIV from 182876-185179, Uncharacterized ORF YBR248C 33.26 1.00 29 1218.9353 1 YBR248C HIS7 SGDID:S000000452,Imidazole glycerol phosphate synthase (glutamine amidotransferase:cyclase), catalyzes the fifth and sixth steps of histidine biosynthesis and also produces 5-aminoimidazole-4-carboxamide ribotide (AICAR), a purine precursor, Chr II from 716460-714802, reverse complement, Verified ORF YPL222W 32.52 0.99 35 1489.5586 1 YPL222W YPL222W SGDID:S000006143,The authentic, non-tagged protein was localized to the mitochondria., Chr XVI from 130161-132227, Uncharacterized ORF YGR180C 20.3 1.00 129 8883.7961 1 YGR180C RNR4 SGDID:S000003412,Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits, Chr VII from 856306-855269, reverse complement, Verified ORF YHR049W 13.288 1.00 29 3051.0076 1 YHR049W FSH1 SGDID:S000001091,Serine hydrolase that localizes to both the nucleus and cytoplasm; sequence is similar to Fsh2p and Fsh3p, Chr VIII from 206455-207186, Verified ORF YLL004W 31.34 0.68 3 90.9988 1 YLL004W ORC3 SGDID:S000003927,Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing, Chr XII from 141072-142922, Verified ORF YBL052C 28.81 0.87 13 548.8128 1 YBL052C SAS3 SGDID:S000000148,Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; sas3 gcn5 double mutation confers lethality, Chr II from 121877-119382, reverse complement, Verified ORF YCL045C 22.386 1.00 6 374.6965 1 YCL045C YCL045C SGDID:S000000550,Hypothetical protein, Chr III from 46905-44623, reverse complement, Uncharacterized ORF YDL135C 13.597 1.00 10 1028.1626 1 YDL135C RDI1 SGDID:S000002294,Rho GDP dissociation inhibitor involved in the localization and regulation of Cdc42p, Chr IV from 219288-218680, reverse complement, Verified ORF YMR237W 23.298 1.00 4 240.0193 1 YMR237W YMR237W SGDID:S000004850,Protein that colocalizes with clathrin-coated vesicles; involved in transport at the trans-Golgi, Chr XIII from 743748-745922, Uncharacterized ORF YDL197C 23.98 0.99 2 115.4305 1 YDL197C ASF2 SGDID:S000002356,Anti-silencing protein that causes derepression of silent loci when overexpressed, Chr IV from 106495-104918, reverse complement, Verified ORF YNL244C 6.66 1.00 32 6717.0821 1 YNL244C SUI1 SGDID:S000005188,Translation initiation factor eIF1; component of a complex involved in recognition of the initiator codon; modulates translation accuracy at the initiation phase, Chr XIV from 187497-187171, reverse complement, Verified ORF YJL111W 27.457 1.00 72 3665.9313 1 YJL111W CCT7 SGDID:S000003647,Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo, Chr X from 207795-209447, Verified ORF YOR093C 70.047 1.00 22 439.0743 1 YOR093C YOR093C SGDID:S000005619,Hypothetical protein, Chr XV from 502453-497507, reverse complement, Uncharacterized ORF YER086W 28.69 1.00 46 2241.4662 1 YER086W ILV1 SGDID:S000000888,Threonine deaminase, catalyzes the first step in isoleucine biosynthesis; expression is under general amino acid control; ILV1 locus exhibits highly positioned nucleosomes whose organization is independent of known ILV1 regulation, Chr V from 328473-330203, Verified ORF YNL135C 8.14 1.00 44 7556.7174 1 YNL135C FPR1 SGDID:S000005079,Peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; also binds to the nonhistone chromatin binding protein Hmo1p and may regulate its assembly or function, Chr XIV from 372228-371884, reverse complement, Verified ORF YHL015W 7.31 1.00 104 19889.363 1 YHL015W RPS20 SGDID:S000001007,Protein component of the small (40S) ribosomal subunit; overproduction suppresses mutations affecting RNA polymerase III-dependent transcription; has similarity to E. coli S10 and rat S20 ribosomal proteins, Chr VIII from 75409-75774, Verified ORF YDR529C 7.42 0.99 1 186.5246 1 YDR529C QCR7 SGDID:S000002937,Subunit 7 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the mitochondrial matrix; N-terminus appears to play a role in complex assembly, Chr IV from 1496540-1496157, reverse complement, Verified ORF YBR072W 10.93 1.00 60 7674.251 1 YBR072W HSP26 SGDID:S000000276,Small heat shock protein with chaperone activity that is regulated by a heat induced transition from an inactive oligomeric (24-mer) complex to an active dimer; induced by heat, upon entry into stationary phase, and during sporulation, Chr II from 382027-382671, Verified ORF YNL284C-B 59.63 1.00 24 562.6668 1 YNL284C-B YNL284C-B SGDID:S000007387,TyB Gag-Pol protein; proteolytically processed to make the Gag, RT, PR, and IN proteins that are required for retrotransposition, Chr XIV from 102232-100928,100926-96964, reverse complement, transposable_element_gene YML071C 34.03 0.98 5 201.2978 1 YML071C COG8 SGDID:S000004536,Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments, Chr XIII from 131572-129749, reverse complement, Verified ORF YCL024W 50.14 0.95 7 185.4138 1 YCL024W KCC4 SGDID:S000000529,Protein kinase of the bud neck involved in the septin checkpoint, associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p, Chr III from 79162-82275, Verified ORF YPR184W 62.568 1.00 9 201.0921 1 YPR184W GDB1 SGDID:S000006388,Glycogen debranching enzyme containing glucanotranferase and alpha-1,6-amyloglucosidase activities, required for glycogen degradation, Chr XVI from 902040-906650, Verified ORF YGR193C 22.45 1.00 24 1494.5133 1 YGR193C PDX1 SGDID:S000003425,Dihydrolipoamide dehydrogenase (E3)-binding protein (E3BP) of the mitochondrial pyruvate dehydrogenase (PDH) complex, plays a structural role in the complex by binding and positioning E3 to the dihydrolipoamide acetyltransferase (E2) core, Chr VII from 885746-884514, reverse complement, Verified ORF YMR130W 14.17 0.98 2 193.3709 1 YMR130W YMR130W SGDID:S000004737,Hypothetical protein, Chr XIII from 532118-533026, Uncharacterized ORF YMR260C 4.73 1.00 45 13300.1422 1 YMR260C TIF11 SGDID:S000004873,Translation initiation factor eIF1A, essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3, Chr XIII from 789838-789377, reverse complement, Verified ORF YDR481C 17.4 1.00 5 401.722 1 YDR481C PHO8 SGDID:S000002889,Repressible alkaline phosphatase, a glycoprotein localized to the vacuole; regulated by levels of inorganic phosphate and by a system consisting of Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides, Chr IV from 1420242-1418542, reverse complement, Verified ORF YBR035C 11.66 0.97 4 465.1982 1 YBR035C PDX3 SGDID:S000000239,Pyridoxine (pyridoxamine) phosphate oxidase, has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism , Chr II from 306955-306269, reverse complement, Verified ORF YCR002C 14.41 0.99 2 192.0906 1 YCR002C CDC10 SGDID:S000000595,Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM, Chr III from 118346-117378, reverse complement, Verified ORF YGL232W 16.08 0.69 1 59.9884 1 YGL232W TAN1 SGDID:S000003201,Putative tRNA acetyltransferase, RNA-binding protein required for the formation of the modified nucleoside N(4)-acetylcytidine in serine and leucine tRNAs but not required for the same modification in 18S rRNA, Chr VII from 62075-62131,62190-63002, Verified ORF YFR037C 27.389 0.99 8 404.2536 1 YFR037C RSC8 SGDID:S000001933,One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; essential for viability and mitotic growth; homolog of SWI\SNF subunit Swi3p, but unlike Swi3p, does not activate transcription of reporters, Chr VI from 229173-227500, reverse complement, Verified ORF YAL016W 21.68 1.00 18 1160.695 1 YAL016W TPD3 SGDID:S000000014,Regulatory subunit A of the heterotrimeric protein phosphatase 2A, which also contains regulatory subunit Cdc55p and either catalytic subunit Pph21p or Pph22p; required for cell morphogenesis and for transcription by RNA polymerase III, Chr I from 124880-126787, Verified ORF YLR264W 3.33 1.00 50 20990.8818 2 YLR264W,YOR167C RPS28B SGDID:S000004254,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps28Bp and has similarity to rat S28 ribosomal protein, Chr XII from 673133-673336, Verified ORF YLR135W 26.18 1.00 10 533.9926 1 YLR135W SLX4 SGDID:S000004125,Subunit of a complex, with Slx1p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p, Chr XII from 413282-415528, Verified ORF YML072C 66.105 1.00 46 972.8109 1 YML072C TCB3 SGDID:S000004537,Contains three calcium and lipid binding domains; localized to the bud; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; mRNA is targeted to the bud via the mRNA transport system involving She2p; C-terminal portion of Tcb1p, Tcb2p and Tcb3p interact, Chr XIII from 129367-124730, reverse complement, Verified ORF YPL153C 29.498 0.76 11 396.2037 1 YPL153C RAD53 SGDID:S000006074,Protein kinase, required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p, Chr XVI from 264191-261726, reverse complement, Verified ORF YKL017C 27.939 1.00 15 750.5598 1 YKL017C HCS1 SGDID:S000001500,Hexameric DNA polymerase alpha-associated DNA helicase A involved in lagging strand DNA synthesis; contains single-stranded DNA stimulated ATPase and dATPase activities; replication protein A stimulates helicase and ATPase activities, Chr XI from 406884-404833, reverse complement, Verified ORF YDL072C 9.76 0.66 1 94.5363 1 YDL072C YDL072C SGDID:S000002230,Endoplasmic reticulum transmembrane protein, homolog of human BAP31 protein, Chr IV from 330447-329836, reverse complement, Uncharacterized ORF YPL190C 17.76 0.87 3 205.4482 1 YPL190C NAB3 SGDID:S000006111,Single stranded DNA binding protein; acidic ribonucleoprotein; required for termination of non-poly(A) transcripts and efficient splicing; interacts with Nrd1p, Chr XVI from 187724-185316, reverse complement, Verified ORF YBR283C 8.43 1.00 20 3316.7087 1 YBR283C SSH1 SGDID:S000000487,Subunit of the Ssh1 translocon complex; Sec61p homolog involved in co-translational pathway of protein translocation; not essential, Chr II from 770411-768939, reverse complement, Verified ORF YOR209C 23.378 1.00 26 1554.787 1 YOR209C NPT1 SGDID:S000005735,Nicotinate phosphoribosyltransferase, acts in the salvage pathway of NAD+ biosynthesis; required for silencing at rDNA and telomeres and has a role in silencing at mating-type loci; localized to the nucleus, Chr XV from 737727-736438, reverse complement, Verified ORF YGR196C 38.408 1.00 8 291.1878 1 YGR196C FYV8 SGDID:S000003428,Protein of unknown function, required for survival upon exposure to K1 killer toxin, Chr VII from 892191-889738, reverse complement, Verified ORF YMR152W 14.6 0.95 2 181.9305 1 YMR152W YIM1 SGDID:S000004760,Protein of unknown function; proposed to be involved in responding to DNA damaging agents, Chr XIII from 563095-564192, Verified ORF YBR023C 41.815 1.00 13 434.6264 1 YBR023C CHS3 SGDID:S000000227,Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan, Chr II from 287925-284428, reverse complement, Verified ORF YNL083W 27.48 0.86 5 218.7543 1 YNL083W SAL1 SGDID:S000005027,Probable transporter, member of the Ca2+-binding subfamily of the mitochondrial carrier family, with two EF-hand motifs; Pet9p and Sal1p have an overlapping function critical for viability; polymorphic in different S. cerevisiae strains, Chr XIV from 471379-473016, Verified ORF YMR061W 34.13 1.00 7 286.7257 1 YMR061W RNA14 SGDID:S000004665,Cleavage and polyadenylation factor I (CF I) component involved in cleavage and polyadenylation of mRNA 3' ends; bridges interaction between Rna15p and Hrp1p in the CF I complex, Chr XIII from 392754-394787, Verified ORF YBR069C 14.36 1.00 7 681.4727 1 YBR069C TAT1 SGDID:S000000273,Amino acid transport protein for valine, leucine, isoleucine, and tyrosine, low-affinity tryptophan and histidine transporter; overexpression confers FK506 resistance, Chr II from 378430-376571, reverse complement, Verified ORF YPL117C 9.89 0.99 20 2798.8125 1 YPL117C IDI1 SGDID:S000006038,Isopentenyl diphosphate:dimethylallyl diphosphate isomerase (IPP isomerase), catalyzes an essential activation step in the isoprenoid biosynthetic pathway; required for viability, Chr XVI from 328729-327863, reverse complement, Verified ORF YML073C 11.61 1.00 159 19145.6368 1 YML073C RPL6A SGDID:S000004538,N-terminally acetylated protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Bp and to rat L6 ribosomal protein; binds to 5.8S rRNA, Chr XIII from 124172-124158,123742-123227, reverse complement, Verified ORF YDR513W 7.39 1.00 22 4161.8186 1 YDR513W GRX2 SGDID:S000002921,Cytoplasmic glutaredoxin, thioltransferase, glutathione-dependent disulfide oxidoreductase involved in maintaining redox state of target proteins, also exhibits glutathione peroxidase activity, expression induced in response to stress, Chr IV from 1471009-1471440, Verified ORF YJR030C 30.75 0.86 4 156.3933 1 YJR030C YJR030C SGDID:S000003791,Putative protein of unknown function; expression repressed in carbon limited vs carbon replete chemostat cultures; YJR030C is a non-essential gene, Chr X from 486111-483874, reverse complement, Uncharacterized ORF YOR311C 6.38 0.99 1 216.9299 1 YOR311C HSD1 SGDID:S000005838,Endoplasmic reticulum (ER)-resident membrane protein, overproduction induces enlargement of ER-like membrane structures and suppresses a temperature-sensitive sly1 mutation, Chr XV from 899925-899053, reverse complement, Verified ORF YPR069C 15.8 1.00 129 11413.9912 1 YPR069C SPE3 SGDID:S000006273,Spermidine synthase, involved in biosynthesis of spermidine and also in biosynthesis of pantothenic acid; spermidine is required for growth of wild-type cells, Chr XVI from 685434-684553, reverse complement, Verified ORF YMR293C 24.99 0.78 1 43.6348 1 YMR293C YMR293C SGDID:S000004907,protein similar to bacterial glutamyl-tRNA amidotransferases, Chr XIII from 856792-855398, reverse complement, Uncharacterized ORF YPL143W 6.12 1.00 95 21700.8675 1 YPL143W RPL33A SGDID:S000006064,N-terminally acetylated ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Bp and has similarity to rat L35a; rpl33a null mutant exhibits slow growth while rpl33a rpl33b double null mutant is inviable, Chr XVI from 282121-282139,282665-282969, Verified ORF YNL064C 19.042 1.00 154 11306.1065 1 YNL064C YDJ1 SGDID:S000005008,Protein chaperone involved in regulation of the HSP90 and HSP70 functions; involved in protein translocation across membranes; member of the DnaJ family, Chr XIV from 507098-505869, reverse complement, Verified ORF YIR026C 16.439 1.00 4 340.1649 1 YIR026C YVH1 SGDID:S000001465,Protein phosphatase involved in vegetative growth at low temperatures, sporulation, and glycogen accumulation; transcription induced by low temperature and nitrogen starvation; member of the dual-specificity family of protein phosphatases, Chr IX from 405964-404870, reverse complement, Verified ORF YCL031C 7.99 0.89 3 467.164 1 YCL031C RRP7 SGDID:S000000536,Essential protein involved in rRNA processing and ribosome biogenesis, Chr III from 65568-64675, reverse complement, Verified ORF YJR106W 9.71 0.97 1 139.6552 1 YJR106W ECM27 SGDID:S000003867,Non-essential protein of unknown function, Chr X from 624752-626929, Verified ORF YGL151W 43.341 0.92 3 89.0256 1 YGL151W NUT1 SGDID:S000003119,Component of the RNA polymerase II mediator complex, which is required for transcriptional activation and also has a role in basal transcription, Chr VII from 217529-220927, Verified ORF YER102W 7.82 1.00 290 51843.7201 2 YER102W,YBL072C RPS8B SGDID:S000000904,Protein component of the small (40S) ribosomal subunit; identical to Rps8Bp and has similarity to rat S8 ribosomal protein, Chr V from 363096-363698, Verified ORF YJR053W 24.28 0.86 2 99.034 1 YJR053W BFA1 SGDID:S000003814,Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell cycle checkpoint pathways that control exit from mitosis, Chr X from 533942-535666, Verified ORF YKL120W 14.64 1.00 11 1050.4043 1 YKL120W OAC1 SGDID:S000001603,Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, and thiosulfate; member of the mitochondrial carrier family, Chr XI from 216988-217962, Verified ORF YMR142C 7.38 1.00 170 32203.0845 1 YMR142C RPL13B SGDID:S000004750,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl13Ap; not essential for viability; has similarity to rat L13 ribosomal protein, Chr XIII from 551206-551203,550800-550205, reverse complement, Verified ORF YDL040C 48.42 1.00 18 519.6998 1 YDL040C NAT1 SGDID:S000002198,Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing, Chr IV from 381435-378871, reverse complement, Verified ORF YAL036C 18.24 1.00 6 459.866 1 YAL036C RBG1 SGDID:S000000034,Member of the DRG family of GTP-binding proteins; interacts with translating ribosomes, Chr I from 76153-75044, reverse complement, Verified ORF YDR488C 18.2 1.00 5 384.0639 1 YDR488C PAC11 SGDID:S000002896,Dynein intermediate chain, acts in the cytoplasmic dynein pathway, forms cortical cytoplasmic microtubule capture site with Num1p; null mutant is defective in nuclear migration, essential in the absence of CIN8, Chr IV from 1430781-1429180, reverse complement, Verified ORF YPL019C 45.683 1.00 149 4559.703 1 YPL019C VTC3 SGDID:S000005940,Vacuolar membrane protein involved in vacuolar polyphosphate accumulation; functions as a regulator of vacuolar H+-ATPase activity and vacuolar transporter chaperones; involved in non-autophagic vacuolar fusion, Chr XVI from 517016-514509, reverse complement, Verified ORF YJL167W 12.468 1.00 78 8745.864 1 YJL167W ERG20 SGDID:S000003703,Farnesyl pyrophosphate synthetase, has both dimethylallyltranstransferase and geranyltranstransferase activities; catalyzes the formation of C15 farnesyl pyrophosphate units for isoprenoid and sterol biosynthesis, Chr X from 105008-106066, Verified ORF YOR198C 22.57 1.00 53 3282.8362 1 YOR198C BFR1 SGDID:S000005724,Component of mRNP complexes associated with polyribosomes; implicated in secretion and nuclear segregation; multicopy suppressor of BFA (Brefeldin A) sensitivity, Chr XV from 720066-718654, reverse complement, Verified ORF YPL085W 77.65 1.00 27 486.1017 1 YPL085W SEC16 SGDID:S000006006,COPII vesicle coat protein required for ER transport vesicle budding and autophagosome formation; Sec16p is bound to the periphery of ER membranes and may act to stabilize initial COPII complexes; interacts with Sec23p, Sec24p and Sec31p, Chr XVI from 387064-393651, Verified ORF YOR308C 25.48 0.99 3 162.9528 1 YOR308C SNU66 SGDID:S000005835,Component of the U4\U6.U5 snRNP complex involved in pre-mRNA splicing via spliceosome; has homology to human SART-1 and to an S. pombe protein; snu66 null mutation confers cold-sensitivity but is not lethal at normal growth temperatures, Chr XV from 896384-894621, reverse complement, Verified ORF YLR014C 42.237 1.00 13 430.284 1 YLR014C PPR1 SGDID:S000004004,Zinc finger transcription factor containing a Zn(2)-Cys(6) binuclear cluster domain, positively regulates transcription of genes involved in uracil biosynthesis; activity may be modulated by interaction with Tup1p, Chr XII from 174981-172267, reverse complement, Verified ORF YHR195W 18.5 1.00 7 528.9702 1 YHR195W NVJ1 SGDID:S000001238,Nuclear envelope protein that interacts with the vacuolar membrane protein Vac8p to promote formation of nucleus-vacuole junctions during piecemeal microautophagy of the nucleus (PMN), Chr VIII from 490747-491712, Verified ORF YEL051W 5.51 1.00 6 1522.3151 1 YEL051W VMA8 SGDID:S000000777,Subunit D of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; plays a role in the coupling of proton transport and ATP hydrolysis, Chr V from 58378-59148, Verified ORF YPL195W 51.73 1.00 4 108.0991 1 YPL195W APL5 SGDID:S000006116,Delta adaptin-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway, suppressor of loss of casein kinase 1 function, Chr XVI from 176222-179020, Verified ORF YMR165C 33.428 1.00 15 627.3151 1 YMR165C PAH1 SGDID:S000004775,Mg sup 2+ \sup -dependent phosphatidate (PA) phosphatase, catalyzes the dephosphorylation of PA to yield diacylglycerol and P sub i \sub , responsible for de novo lipid synthesis; homologous to mammalian lipin 1, Chr XIII from 592627-590039, reverse complement, Verified ORF YGL241W 33.307 0.99 4 166.2128 1 YGL241W KAP114 SGDID:S000003210,Karyopherin, responsible for nuclear import of Spt15p, histones H2A and H2B, and Nap1p; amino terminus shows similarity to those of other importins, particularly Cse1p; localization is primarily nuclear, Chr VII from 45445-48459, Verified ORF YGR237C 32.02 1.00 8 349.2798 1 YGR237C YGR237C SGDID:S000003469,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, Chr VII from 965660-963303, reverse complement, Uncharacterized ORF YHR143W-A 2.05 0.99 14 9451.7947 1 YHR143W-A RPC10 SGDID:S000001185,RNA polymerase subunit, found in RNA polymerase complexes I, II, and III, Chr VIII from 387236-387448, Verified ORF YMR106C 22.66 0.82 1 50.5893 1 YMR106C YKU80 SGDID:S000004712,Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair, Chr XIII from 480189-478300, reverse complement, Verified ORF YJR010W 19.01 0.99 5 364.0223 1 YJR010W MET3 SGDID:S000003771,ATP sulfurylase, catalyzes the primary step of intracellular sulfate activation, essential for assimilatory reduction of sulfate to sulfide, involved in methionine metabolism, Chr X from 456154-457689, Verified ORF YLL050C 8.67 1.00 98 15801.9939 1 YLL050C COF1 SGDID:S000003973,Cofilin, promotes actin filament depolarization in a pH-dependent manner; binds both actin monomers and filaments and severs filaments , thought to be regulated by phosphorylation at SER4, ubiquitous and essential in eukaryotes, Chr XII from 40413-40400,40220-39803, reverse complement, Verified ORF YBR202W 38.985 0.86 6 185.0363 1 YBR202W CDC47 SGDID:S000000406,Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase, Chr II from 625767-628304, Verified ORF YMR002W 1.07 0.99 4 5173.8796 1 YMR002W YMR002W SGDID:S000004604,Hypothetical protein, Chr XIII from 272193-272663, Uncharacterized ORF YCR021C 6.11 0.87 2 398.119 1 YCR021C HSP30 SGDID:S000000615,Hydrophobic plasma membrane localized, stress-responsive protein that negatively regulates the H(+)-ATPase Pma1p; induced by heat shock, ethanol treatment, weak organic acid, glucose limitation, and entry into stationary phase, Chr III from 157103-156105, reverse complement, Verified ORF YJL130C 98.368 1.00 422 5997.4069 1 YJL130C URA2 SGDID:S000003666,Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes the first two enzymatic steps in the de novo biosynthesis of pyrimidines; both activities are subject to feedback inhibition by UTP, Chr X from 172286-165642, reverse complement, Verified ORF YHR063C 16.63 0.99 3 249.6715 1 YHR063C PAN5 SGDID:S000001105,2-dehydropantoate 2-reductase, part of the pantothenic acid pathway, structurally homologous to E. coli panE, Chr VIII from 225171-224032, reverse complement, Verified ORF YGR133W 6.82 0.81 14 2324.5216 1 YGR133W PEX4 SGDID:S000003365,Peroxisomal ubiquitin conjugating enzyme required for peroxisomal matrix protein import and peroxisome biogenesis, Chr VII from 756901-757452, Verified ORF YDR122W 47.158 0.69 2 40.9099 1 YDR122W KIN1 SGDID:S000002529,Serine\threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin2p, Chr IV from 694697-697891, Verified ORF YDR023W 22.539 1.00 199 12343.0743 1 YDR023W SES1 SGDID:S000002430,Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p, Chr IV from 489505-490893, Verified ORF YNL256W 34.07 0.93 5 190.8032 1 YNL256W FOL1 SGDID:S000005200,Multifunctional enzyme of the folic acid biosynthesis pathway, has dihydropteroate synthetase, dihydro-6-hydroxymethylpterin pyrophosphokinase, and dihydroneopterin aldolase activities, Chr XIV from 164624-167098, Verified ORF YML100W 37.682 0.98 10 363.5775 1 YML100W TSL1 SGDID:S000004566,Large subunit of trehalose 6-phosphate synthase (Tps1p)\phosphatase (Tps2p) complex, which converts uridine-5'-diphosphoglucose and glucose 6-phosphate to trehalose, homologous to Tps3p and may share function, Chr XIII from 70624-73920, Verified ORF YOL063C 27.45 0.90 4 183.3433 1 YOL063C CRT10 SGDID:S000005424,Protein required for normal hydroxyurea resistance; one of constitutive RNR transcription (CRT) regulators, Chr XV from 210265-207392, reverse complement, Verified ORF YGL049C 33.269 0.99 2 83.2013 1 YGL049C TIF4632 SGDID:S000003017,Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); homologous to Tif4631p, Chr VII from 409607-406863, reverse complement, Verified ORF YHR197W 31.685 1.00 9 397.0943 1 YHR197W RIX1 SGDID:S000001240,Essential protein involved in the processing of the ITS2 region of the rRNA locus; required for the maturation and nuclear export of the 60S ribosomal subunit, Chr VIII from 493896-496187, Verified ORF YHR009C 18.983 0.97 3 214.3053 1 YHR009C YHR009C SGDID:S000001051,Putative protein of unknown function; not an essential gene, Chr VIII from 125675-124104, reverse complement, Uncharacterized ORF YBL068W 14.074 1.00 3 297.9947 1 YBL068W PRS4 SGDID:S000000164,5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, histidine, and tryptophan biosynthesis; one of a five related enzymes, which are active as heteromultimeric complexes, Chr II from 92412-93395, Verified ORF YKR010C 32.817 0.94 6 240.262 1 YKR010C TOF2 SGDID:S000001718,Nonessential mitochondrial protein of unknown function with sequence similarity to Net1p; identified as a topoisomerase I (Top1p) binding protein; displays synthetic genetic interactions with TOP1 and HPR1, Chr XI from 460882-458567, reverse complement, Verified ORF YDR135C 53.51 0.99 4 103.4582 1 YDR135C YCF1 SGDID:S000002542,Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR, Chr IV from 727548-723001, reverse complement, Verified ORF YOR118W 28.41 0.93 6 274.5793 1 YOR118W YOR118W SGDID:S000005644,Hypothetical protein, Chr XV from 546858-548561, Uncharacterized ORF YLR448W 11.56 1.00 171 20679.6502 1 YLR448W RPL6B SGDID:S000004440,Protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Bp and to rat L6 ribosomal protein; binds to 5.8S rRNA, Chr XII from 1028850-1028864,1029249-1029764, Verified ORF YNL001W 19.528 0.86 15 923.4999 1 YNL001W DOM34 SGDID:S000004946,Probable RNA-binding protein, functions in protein translation to promote G1 progression and differentiation, required for meiotic cell division, Chr XIV from 627458-628618, Verified ORF YKL015W 19.17 0.69 3 150.9569 1 YKL015W PUT3 SGDID:S000001498,Transcriptional activator of proline utilization genes, constitutively binds PUT1 and PUT2 promoter sequences and undergoes a conformational change to form the active state; has a Zn(2)-Cys(6) binuclear cluster domain, Chr XI from 408187-411126, Verified ORF YFR051C 11.39 1.00 6 736.4316 1 YFR051C RET2 SGDID:S000001947,Delta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER, Chr VI from 251790-250150, reverse complement, Verified ORF YGR094W 53.067 1.00 292 7692.4242 1 YGR094W VAS1 SGDID:S000003326,Mitochondrial and cytoplasmic valyl-tRNA synthetase, Chr VII from 672190-675504, Verified ORF YBR019C 25.027 0.75 5 209.4726 1 YBR019C GAL10 SGDID:S000000223,UDP-glucose-4-epimerase, catalyzes the interconversion of UDP-galactose and UDP-D-glucose in galactose metabolism; also catalyzes the conversion of alpha-D-glucose or alpha-D-galactose to their beta-anomers, Chr II from 278352-276253, reverse complement, Verified ORF YLL063C 18.46 0.87 2 131.7717 1 YLL063C AYT1 SGDID:S000003986,Acetyltransferase; catalyzes trichothecene 3-O-acetylation, suggesting a possible role in trichothecene biosynthesis, Chr XII from 16072-14648, reverse complement, Verified ORF YOR239W 23.27 1.00 16 961.2326 1 YOR239W ABP140 SGDID:S000005765,Nonessential protein that binds actin filaments and localizes to actin patches and cables, has similarity to S-adenosylmethionine (AdoMet)-dependent methyltransferases, Chr XV from 784858-785688,785690-786745, Verified ORF YNL103W-A 1.29 0.67 3 2178.2677 1 YNL103W-A YNL103W-A SGDID:S000028701,Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching, Chr XIV from 426721-426810, Dubious ORF YNL098C 15.599 0.97 3 260.7961 1 YNL098C RAS2 SGDID:S000005042,GTP-binding protein that regulates the nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; homolog of mammalian Ras proto-oncogenes, Chr XIV from 440572-439604, reverse complement, Verified ORF YLR332W 7.5 0.96 1 178.943 1 YLR332W MID2 SGDID:S000004324,O-glycosylated plasma membrane protein that acts as a sensor for cell wall integrity signaling and activates the pathway; interacts with Rom2p, a guanine nucleotide exchange factor for Rho1p, and with cell integrity pathway protein Zeo1p, Chr XII from 790676-791806, Verified ORF YGR232W 9.61 0.98 2 285.1265 1 YGR232W NAS6 SGDID:S000003464,Regulatory, non-ATPase subunit of the 26S proteasome; homolog of the human oncoprotein gankyrin, which interacts with the retinoblastoma tumor suppressor (Rb) and cyclin-dependent kinase 4\6, Chr VII from 953963-954649, Verified ORF YMR006C 14.64 0.67 1 63.9791 1 YMR006C PLB2 SGDID:S000004608,Phospholipase B (lysophospholipase) involved in phospholipid metabolism; displays transacylase activity in vitro; overproduction confers resistance to lysophosphatidylcholine, Chr XIII from 279681-277561, reverse complement, Verified ORF YDL022W 9.16 1.00 35 5341.6752 1 YDL022W GPD1 SGDID:S000002180,NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p, Chr IV from 411822-412997, Verified ORF YER024W 35.545 0.73 6 172.2663 1 YER024W YAT2 SGDID:S000000826,Carnitine acetyltransferase; has similarity to Yat1p, which is a carnitine acetyltransferase associated with the mitochondrial outer membrane, Chr V from 202191-204962, Verified ORF YAL066W 4.488 0.99 3 925.1422 1 YAL066W YAL066W SGDID:S000000061,Hypothetical protein, Chr I from 10092-10400, Dubious ORF YHR064C 24.14 1.00 345 19979.5978 1 YHR064C SSZ1 SGDID:S000001106,Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that binds the ribosome via the Zuo1p subunit; also involved in pleiotropic drug resistance via sequential activation of PDR1 and PDR5; binds ATP, Chr VIII from 227143-225527, reverse complement, Verified ORF YPL273W 12.069 1.00 13 1505.8335 1 YPL273W SAM4 SGDID:S000006194,S-adenosylmethionine-homocysteine methyltransferase, functions along with Mht1p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine\AdoMet ratio, Chr XVI from 25087-26064, Verified ORF YBR189W 10.16 1.00 198 27244.3464 1 YBR189W RPS9B SGDID:S000000393,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9Bp and has similarity to E. coli S4 and rat S9 ribosomal proteins, Chr II from 604503-604509,604923-605503, Verified ORF YJL183W 15.63 0.68 4 243.2847 1 YJL183W MNN11 SGDID:S000003719,Subunit of a Golgi mannosyltransferase complex that also contains Anp1p, Mnn9p, Mnn10p, and Hoc1p, and mediates elongation of the polysaccharide mannan backbone; has homology to Mnn10p, Chr X from 84066-85334, Verified ORF YHR003C 19.57 0.87 2 124.2977 1 YHR003C YHR003C SGDID:S000001045,Protein of unknown function, localized to the mitochondrial outer membrane, Chr VIII from 111312-110023, reverse complement, Verified ORF YOR151C 45.43 1.00 19 584.6766 1 YOR151C RPB2 SGDID:S000005677,RNA polymerase II second largest subunit B150, part of central core; similar to bacterial beta subunit, Chr XV from 616672-612998, reverse complement, Verified ORF YOL058W 14.988 1.00 11 1026.0154 1 YOL058W ARG1 SGDID:S000005419,Arginosuccinate synthetase, catalyzes the formation of L-argininosuccinate from citrulline and L-aspartate in the arginine biosynthesis pathway; potential Cdc28p substrate, Chr XV from 219210-220472, Verified ORF YML126C 17.1 1.00 78 6376.8089 1 YML126C ERG13 SGDID:S000004595,3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase, catalyzes the formation of HMG-CoA from acetyl-CoA and acetoacetyl-CoA; involved in the second step in mevalonate biosynthesis, Chr XIII from 20536-19061, reverse complement, Verified ORF YHL007C 36.87 1.00 9 341.2512 1 YHL007C STE20 SGDID:S000000999,Signal transducing kinase of the PAK (p21-activated kinase) family, involved in pheromone response and pseudohyphal\invasive growth pathways, activated by Cdc42p; binds Ste4p at a GBB motif present in noncatalytic domains of PAK kinases, Chr VIII from 97933-95114, reverse complement, Verified ORF YPR041W 21.498 1.00 32 2080.9269 1 YPR041W TIF5 SGDID:S000006245,Translation initiation factor eIF-5; N-terminal domain functions as a GTPase-activating protein to mediate hydrolysis of ribosome-bound GTP; C-terminal domain is the core of ribosomal preinitiation complex formation, Chr XVI from 648701-649918, Verified ORF YLR258W 27.717 0.98 4 197.7173 1 YLR258W GSY2 SGDID:S000004248,Glycogen synthase, similar to Gsy1p; expression induced by glucose limitation, nitrogen starvation, heat shock, and stationary phase; activity regulated by cAMP-dependent, Snf1p and Pho85p kinases as well as by the Gac1p-Glc7p phosphatase, Chr XII from 660718-662835, Verified ORF YHR171W 31.818 0.94 7 289.1065 1 YHR171W ATG7 SGDID:S000001214,Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes; mediates the conjugation of Atg12p with Atg5p and Atg8p with phosphatidylethanolamine, required steps in autophagosome formation., Chr VIII from 445713-447605, Verified ORF YJL050W 52.58 1.00 23 611.5221 1 YJL050W MTR4 SGDID:S000003586,Dead-box family ATP dependent helicase required for mRNA export from the nucleus; co-factor of the exosome complex, required for 3' end formation of 5.8S rRNA, Chr X from 342439-345660, Verified ORF YBL085W 47.448 1.00 8 235.7094 1 YBL085W BOI1 SGDID:S000000181,Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain, Chr II from 63873-66815, Verified ORF YHR208W 16.42 1.00 174 14814.2956 1 YHR208W BAT1 SGDID:S000001251,Mitochondrial branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during logarithmic phase and repressed during stationary phase, Chr VIII from 517532-518713, Verified ORF YOL123W 14.239 1.00 13 1276.347 1 YOL123W HRP1 SGDID:S000005483,Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA\B family member that binds to poly (A) signal sequences, Chr XV from 87844-89448, Verified ORF YOR136W 11.04 1.00 44 5571.7101 1 YOR136W IDH2 SGDID:S000005662,Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle, Chr XV from 580251-581360, Verified ORF YAR042W 48.814 0.94 7 188.4457 1 YAR042W SWH1 SGDID:S000000081,Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats; localizes to the Golgi and the nucleus-vacuole junction, Chr I from 192613-196179, Verified ORF YOR327C 4.58 1.00 4 1220.9543 1 YOR327C SNC2 SGDID:S000005854,Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; member of the synaptobrevin\VAMP family of R-type v-SNARE proteins, Chr XV from 931078-930731, reverse complement, Verified ORF YGL094C 38.76 0.97 6 209.9153 1 YGL094C PAN2 SGDID:S000003062,Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex, which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes, Chr VII from 334468-331121, reverse complement, Verified ORF YLR130C 8.28 0.71 2 239.7523 1 YLR130C ZRT2 SGDID:S000004120,Low-affinity zinc transporter of the plasma membrane; transcription is induced under low-zinc conditions by the Zap1p transcription factor, Chr XII from 404063-402795, reverse complement, Verified ORF YDR234W 28.06 1.00 19 946.6094 1 YDR234W LYS4 SGDID:S000002642,Homoaconitase, catalyzes the conversion of homocitrate to homoisocitrate, which is a step in the lysine biosynthesis pathway, Chr IV from 931125-933206, Verified ORF YDR081C 28.265 0.83 4 164.2078 1 YDR081C PDC2 SGDID:S000002488,Transcription factor required for the synthesis of the glycolytic enzyme pyruvate decarboxylase, required for high level expression of both the THI and the PDC genes, Chr IV from 610078-607301, reverse complement, Verified ORF YLR384C 45.906 1.00 5 152.2668 1 YLR384C IKI3 SGDID:S000004376,Subunit of RNA polymerase II elongator histone acetyltransferase complex, involved in maintaining its structural integrity; negatively regulates exocytosis independent of transcription, homolog of human familial dysautonomia (FD) protein, Chr XII from 892900-888851, reverse complement, Verified ORF YCR012W 37.417 1.00 1163 43452.5895 1 YCR012W PGK1 SGDID:S000000605,3-phosphoglycerate kinase, catalyzes transfer of high-energy phosphoryl groups from the acyl phosphate of 1,3-bisphosphoglycerate to ADP to produce ATP; key enzyme in glycolysis and gluconeogenesis, Chr III from 137744-138994, Verified ORF YKR064W 35.49 1.00 11 433.3029 1 YKR064W YKR064W SGDID:S000001772,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; detectable in highly purified mitochondria, Chr XI from 562189-564780, Uncharacterized ORF YNL220W 23.89 1.00 56 3277.0026 1 YNL220W ADE12 SGDID:S000005164,Adenylosuccinate synthase, catalyzes the first committed step in the 'de novo' biosynthesis of adenosine, Chr XIV from 234414-235715, Verified ORF YJL186W 25.01 1.00 6 335.3841 1 YJL186W MNN5 SGDID:S000003722,Alpha-1,2-mannosyltransferase, responsible for addition of the second alpha-1,2-linked mannose of the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment, Chr X from 80153-81913, Verified ORF YDR005C 10.08 1.00 4 554.759 1 YDR005C MAF1 SGDID:S000002412,Negative regulator of RNA polymerase III; component of several signaling pathways that repress polymerase III transcription in response to changes in cellular environment; targets the initiation factor TFIIIB, Chr IV from 458100-458095,458014-456833, reverse complement, Verified ORF YJL198W 20.55 0.94 6 383.6826 1 YJL198W PHO90 SGDID:S000003734,Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth, Chr X from 60843-63488, Verified ORF YHL021C 14.65 0.99 5 472.3593 1 YHL021C YHL021C SGDID:S000001013,The authentic, non-tagged protein was localized to the mitochondria, Chr VIII from 65856-64459, reverse complement, Uncharacterized ORF YPR070W 21.467 0.94 2 122.431 1 YPR070W MED1 SGDID:S000006274,Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation, Chr XVI from 685895-687595, Verified ORF YKR016W 29.65 1.00 3 141.4495 1 YKR016W YKR016W SGDID:S000001724,The authentic, non-tagged protein was localized to the mitochondria, Chr XI from 469360-470982, Uncharacterized ORF YPR133C 26.54 1.00 15 790.1239 1 YPR133C SPN1 SGDID:S000006337,Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II, probable transcriptional elongation factor; metazoan homologs contain an acidic N terminus; mutations in the gene confer an Spt- phenotype, Chr XVI from 797206-795974, reverse complement, Verified ORF YPL232W 7.61 0.96 2 352.713 1 YPL232W SSO1 SGDID:S000006153,Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane; forms a complex, with t-SNARE Sec9p, that binds v-SNARE Snc2p; also required for sporulation; syntaxin homolog that is functionally redundant with Sso2p, Chr XVI from 107275-108147, Verified ORF YER001W 31.473 1.00 8 355.3503 1 YER001W MNN1 SGDID:S000000803,Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family, Chr V from 153519-155807, Verified ORF YDR221W 22.9 0.73 1 44.5648 1 YDR221W GTB1 SGDID:S000002629,Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p, involved in removal of two glucose residues from N-linked glycans during glycoprotein biogenesis in the ER, Chr IV from 907326-909434, Verified ORF YGR116W 70.1030000000001 1.00 14 279.1877 1 YGR116W SPT6 SGDID:S000003348,Essential protein that interacts with histones and is involved in nucleosome disassembly and reassembly during transcription elongation, Chr VII from 720413-724768, Verified ORF YGR264C 35.477 1.00 81 3191.8541 1 YGR264C MES1 SGDID:S000003496,Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs, Chr VII from 1021859-1019604, reverse complement, Verified ORF YHR074W 23.936 1.00 6 350.4326 1 YHR074W QNS1 SGDID:S000001116,Glutamine-dependent NAD(+) synthetase, essential for the formation of NAD(+) from nicotinic acid adenine dinucleotide, Chr VIII from 246195-248339, Verified ORF YPL215W 17.42 0.67 1 53.7689 1 YPL215W CBP3 SGDID:S000006136,Mitochondrial protein required for assembly of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex); interacts with Cbp4p and function is partially redundant with that of Cbp4p, Chr XVI from 147415-148422, Verified ORF YJR084W 17.49 0.95 3 227.8032 1 YJR084W CSN12 SGDID:S000003844,Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling, Chr X from 583648-584919, Verified ORF YGL234W 30.198 1.00 171 7916.3109 1 YGL234W ADE5,Bifunctional enzyme of the 'de novo' purine nucleotide biosynthetic pathway, contains aminoimidazole ribotide synthetase and glycinamide ribotide synthetase activities,7 SGDID:S000003203, Chr VII from 56482-58890, Verified ORF YKL198C 26.28 0.88 6 280.8752 1 YKL198C PTK1 SGDID:S000001681,Putative serine\threonine protein kinase that regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein, Chr XI from 70223-68274, reverse complement, Verified ORF YCL059C 17.82 1.00 5 392.2538 1 YCL059C KRR1 SGDID:S000000564,Essential nucleolar protein required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit, Chr III from 23379-22429, reverse complement, Verified ORF YER164W 74.878 1.00 19 354.7351 1 YER164W CHD1 SGDID:S000000966,Nucleosome remodeling factor that functions in regulation of transcription elongation; contains a chromo domain, a helicase domain and a DNA-binding domain; component of both the SAGA and SILK complexes, Chr V from 505387-509793, Verified ORF YJR152W 13.41 0.65 2 135.525 1 YJR152W DAL5 SGDID:S000003913,Allantoin permease; ureidosuccinate permease; expression is constitutive but sensitive to nitrogen catabolite repression, Chr X from 719582-721213, Verified ORF YER003C 18.667 1.00 101 7564.0041 1 YER003C PMI40 SGDID:S000000805,Mannose-6-phosphate isomerase, catalyzes the interconversion of fructose-6-P and mannose-6-P; required for early steps in protein mannosylation, Chr V from 159117-159087,158993-157735, reverse complement, Verified ORF YPR108W 16.98 1.00 6 493.9903 1 YPR108W RPN7 SGDID:S000006312,Essential, non-ATPase regulatory subunit of the 26S proteasome, similar to another S. cerevisiae regulatory subunit, Rpn5p, as well as to mammalian proteasome subunits, Chr XVI from 742452-743741, Verified ORF YBR085W 13.97 0.89 2 178.1264 1 YBR085W AAC3 SGDID:S000000289,Mitochondrial inner membrane ADP\ATP translocator, exchanges cytosolic ADP for mitochondrially synthesized ATP; expressed under anaerobic conditions; similar to Pet9p and Aac1p; has roles in maintenance of viability and in respiration, Chr II from 415977-416900, Verified ORF YDR385W 43.354 1.00 1039 33503.5854 2 YDR385W,YOR133W EFT2 SGDID:S000002793,Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin, Chr IV from 1243222-1245750, Verified ORF YML046W 30.87 0.81 3 110.046 1 YML046W PRP39 SGDID:S000004509,U1 snRNP protein involved in splicing, contains multiple tetriatricopeptide repeats, Chr XIII from 181474-183363, Verified ORF YBR109C 9.518 1.00 42 6168.9109 1 YBR109C CMD1 SGDID:S000000313,Calmodulin; Ca++ binding protein that regulates Ca++ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca++ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin, Chr II from 458356-457913, reverse complement, Verified ORF YLL016W 40.788 1.00 10 342.746 1 YLL016W SDC25 SGDID:S000003939,Non-essential Ras guanine nucleotide exchange factor (GEF) localized to the membrane; expressed in poor nutrients and on non-fermentable carbon sources; homologous to CDC25; contains a stop codon in S288C; full-length gene includes YLL017W, Chr XII from 112846-115992, pseudogene YKL080W 18.35 1.00 79 6018.6062 1 YKL080W VMA5 SGDID:S000001563,Subunit C of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane, Chr XI from 284674-285852, Verified ORF YDL153C 33.599 1.00 4 166.4326 1 YDL153C SAS10 SGDID:S000002312,Component of the small (ribosomal) subunit (SSU) processosome required for pre-18S rRNa processing; essential nucleolar protein that, when overproduced, disrupts silencing, Chr IV from 183019-181187, reverse complement, Verified ORF YIL137C 38.516 1.00 4 145.1856 1 YIL137C YIL137C SGDID:S000001399,Putative metalloprotease, Chr IX from 92788-89948, reverse complement, Uncharacterized ORF YLL012W 23.357 0.78 8 373.4843 1 YLL012W YEH1 SGDID:S000003935,Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes, Chr XII from 125533-127254, Verified ORF YLL001W 37.47 1.00 6 223.8579 1 YLL001W DNM1 SGDID:S000003924,Dynamin-related GTPase required for mitochondrial fission and the maintenance of mitochondrial morphology, assembles on the cytoplasmic face of mitochondrial tubules at sites at which division will occur; also participates in endocytosis, Chr XII from 147889-150162, Verified ORF YDL150W 18.95 1.00 13 959.0451 1 YDL150W RPC53 SGDID:S000002309,RNA polymerase III subunit C53, Chr IV from 183344-184612, Verified ORF YBL075C 26.178 0.81 1 43.2567 1 YBL075C SSA3 SGDID:S000000171,ATPase involved in protein folding and the response to stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm, Chr II from 86446-84497, reverse complement, Verified ORF YHR108W 20.19 1.00 6 415.451 1 YHR108W GGA2 SGDID:S000001150,Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi, Chr VIII from 328306-330063, Verified ORF YML093W 40.52 1.00 12 414.0156 1 YML093W UTP14 SGDID:S000004558,Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA, Chr XIII from 83090-85789, Verified ORF YHR082C 33.05 0.66 2 55.8351 1 YHR082C KSP1 SGDID:S000001124,Nonessential putative serine\threonine protein kinase of unknown cellular role; overproduction causes allele-specific suppression of the prp20-10 mutation, Chr VIII from 271550-268461, reverse complement, Verified ORF YER036C 26.817 1.00 98 5108.8222 1 YER036C ARB1 SGDID:S000000838,ATPase of the ATP-binding cassette (ABC) family involved in 40S and 60S ribosome biogenesis, has similarity to Gcn20p; shuttles from nucleus to cytoplasm, physically interacts with Tif6p, Lsg1p, Chr V from 225198-223366, reverse complement, Uncharacterized ORF YFL039C 18.22 1.00 380 29156.8187 1 YFL039C ACT1 SGDID:S000001855,Actin, structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions, Chr VI from 54695-54686,54377-53260, reverse complement, Verified ORF YNL239W 25.32 0.99 4 218.6434 1 YNL239W LAP3 SGDID:S000005183,Aminopeptidase of cysteine protease family, has a DNA binding activity and acts as bleomycin hydrolase in vitro; transcription is regulated by galactose via Gal4p, Chr XIV from 200570-201934, Verified ORF YDR398W 17.297 0.73 2 118.0013 1 YDR398W UTP5 SGDID:S000002806,Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA, Chr IV from 1267463-1269394, Verified ORF YNL168C 7.598 1.00 11 2023.9431 1 YNL168C YNL168C SGDID:S000005112,The authentic, non-tagged protein was localized to mitochondria, Chr XIV from 318811-318032, reverse complement, Uncharacterized ORF YDR439W 16.23 0.67 3 173.134 1 YDR439W LRS4 SGDID:S000002847,Protein involved in rDNA silencing; positively charged coiled-coil protein with limited similarity to myosin, Chr IV from 1339668-1340711, Verified ORF YDR381W 8.86 1.00 29 4575.8227 1 YDR381W YRA1 SGDID:S000002789,Nuclear protein that binds to RNA and to Mex67p, required for export of poly(A)+ mRNA from the nucleus; member of the REF (RNA and export factor binding proteins) family; another family member, Yra2p, can substitute for Yra1p function, Chr IV from 1236550-1236834,1237601-1237996, Verified ORF YER127W 12.41 1.00 4 450.602 1 YER127W LCP5 SGDID:S000000929,Essential protein involved in maturation of 18S rRNA; depletion leads to inhibited pre-rRNA processing and reduced polysome levels; localizes primarily to the nucleolus, Chr V from 414477-415550, Verified ORF YPL091W 19.88 1.00 35 2461.2548 1 YPL091W GLR1 SGDID:S000006012,Cytosolic and mitochondrial glutathione oxidoreductase, converts oxidized glutathione to reduced glutathione, Chr XVI from 375499-376950, Verified ORF YKR031C 73.4700000000001 0.80 6 91.3347 1 YKR031C SPO14 SGDID:S000001739,Phospholipase D, catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid; involved in Sec14p-independent secretion; required for meiosis and spore formation; differently regulated in secretion and meiosis, Chr XI from 506037-500986, reverse complement, Verified ORF YJR090C 44.61 1.00 5 156.6905 1 YJR090C GRR1 SGDID:S000003850,F-box protein component of the SCF ubiquitin-ligase complex, required for Cln1p and Cln2p degradation; involved in carbon catabolite repression, glucose-dependent divalent cation transport, high-affinity glucose transport, and morphogenesis, Chr X from 594242-590787, reverse complement, Verified ORF YCL011C 17.49 1.00 12 959.1716 1 YCL011C GBP2 SGDID:S000000517,Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Hrb1p and Npl3p; also binds single-stranded telomeric repeat sequence in vitro, Chr III from 103358-102075, reverse complement, Verified ORF YPL059W 9.567 1.00 12 1753.5186 1 YPL059W GRX5 SGDID:S000005980,Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; mitochondrial matrix protein involved in the synthesis\assembly of iron-sulfur centers; monothiol glutaredoxin subfamily member along with Grx3p and Grx4p, Chr XVI from 444576-445028, Verified ORF YHR132C 12.58 0.99 7 770.1184 1 YHR132C ECM14 SGDID:S000001174,Putative metalloprotease with similarity to the zinc carboxypeptidase family, required for normal cell wall assembly, Chr VIII from 369797-368505, reverse complement, Verified ORF YIL022W 26.169 1.00 6 320.5302 1 YIL022W TIM44 SGDID:S000001284,Peripheral mitochondrial membrane protein involved in mitochondrial protein import, tethers essential chaperone Ssc1p to the translocon channel at the matrix side of the inner membrane, Chr IX from 311163-312458, Verified ORF YPR067W 9.63 0.90 13 1698.4958 1 YPR067W ISA2 SGDID:S000006271,Protein required for maturation of mitochondrial and cytosolic Fe\S proteins, localizes to the mitochondrial intermembrane space, overexpression of ISA2 suppresses grx5 mutations, Chr XVI from 682217-682774, Verified ORF YGR254W 21.889 1.00 845 53967.9225 1 YGR254W ENO1 SGDID:S000003486,Enolase I, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is repressed in response to glucose, Chr VII from 1000932-1002245, Verified ORF YLR336C 43.19 1.00 7 226.579 1 YLR336C SGD1 SGDID:S000004328,Essential nuclear protein with a possible role in the osmoregulatory glycerol response; interacts with phospholipase C (Plc1p); putative homolog of human NOM1 which is implicated in acute myeloid leukemia, Chr XII from 802396-799697, reverse complement, Verified ORF YDR441C 5.23 0.86 1 229.8802 1 YDR441C APT2 SGDID:S000002849,Apparent pseudogene, not transcribed or translated under normal conditions; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity, Chr IV from 1345054-1344509, reverse complement, Verified ORF YDR101C 20.865 1.00 7 469.0126 1 YDR101C ARX1 SGDID:S000002508,Protein associated with the ribosomal export complex, Chr IV from 657464-655683, reverse complement, Verified ORF YDL174C 25.354 1.00 5 275.6947 1 YDL174C DLD1 SGDID:S000002333,D-lactate dehydrogenase, oxidizes D-lactate to pyruvate, transcription is heme-dependent, repressed by glucose, and derepressed in ethanol or lactate; located in the mitochondrial inner membrane, Chr IV from 147590-145827, reverse complement, Verified ORF YMR121C 6.05 0.86 1 198.7229 1 YMR121C RPL15B SGDID:S000004728,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Ap and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA, Chr XIII from 510347-509733, reverse complement, Verified ORF YDR224C 5.17 1.00 83 22443.5969 2 YDR224C,YBL002W HTB1 SGDID:S000002632,One of two nearly identical (see HTB2) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation , Chr IV from 914708-914313, reverse complement, Verified ORF YBR261C 8.1 0.99 15 2562.9866 1 YBR261C YBR261C SGDID:S000000465,Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YBR261C is not an essential gene, Chr II from 735525-734827, reverse complement, Uncharacterized ORF YPR102C 7.26 1.00 121 23299.8788 2 YPR102C,YGR085C RPL11A SGDID:S000006306,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl11Bp; involved in ribosomal assembly; depletion causes degradation of proteins and RNA of the 60S subunit; has similarity to E. coli L5 and rat L11, Chr XVI from 731746-731222, reverse complement, Verified ORF YNL141W 14.74 1.00 25 2371.0867 1 YNL141W AAH1 SGDID:S000005085,Adenine deaminase (adenine aminohydrolase), involved in purine salvage and nitrogen catabolism, Chr XIV from 359598-360641, Verified ORF YLR168C 12.3 0.87 9 889.9417 1 YLR168C YLR168C SGDID:S000004158,Putative protein of unknown function that may be involved in intramitochondrial sorting; has homology to a domain of human PREL1; the green fluorescent protein (GFP)-tagged protein localizes to mitochondria, Chr XII from 500272-499580, reverse complement, Uncharacterized ORF YPL123C 20.687 0.76 2 102.719 1 YPL123C RNY1 SGDID:S000006044,RNAse; member of the T(2) family of endoribonucleases, Chr XVI from 318944-317640, reverse complement, Verified ORF YDR498C 14.659 0.74 9 635.1477 1 YDR498C SEC20 SGDID:S000002906,Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to the ER; required for N- and O-glycosylation in the Golgi but not in the ER; forms a complex with the cytosolic Tip20p, Chr IV from 1446986-1445835, reverse complement, Verified ORF YJR096W 16.396 0.91 10 775.9047 1 YJR096W YJR096W SGDID:S000003857,Putative xylose and arabinose reductase, Chr X from 611113-611961, Uncharacterized ORF YEL034W 8.599 1.00 114 18533.6866 1 YEL034W HYP2 SGDID:S000000760,Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Anb1p; undergoes an essential hypusination modification; expressed under aerobic conditions, Chr V from 85676-86149, Verified ORF YOR335C 44.41 1.00 247 7775.3705 1 YOR335C ALA1 SGDID:S000005862,Cytoplasmic alanyl-tRNA synthetase, required for protein synthesis; point mutation (cdc64-1 allele) causes cell cycle arrest at G1; lethality of null mutation is functionally complemented by human homolog, Chr XV from 949106-946230, reverse complement, Verified ORF YHR135C 16.288 1.00 17 1459.1034 1 YHR135C YCK1 SGDID:S000001177,Palmitoylated, plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck2p in morphogenesis, proper septin assembly, endocytic trafficking; provides an essential function overlapping with that of Yck2p, Chr VIII from 374313-372697, reverse complement, Verified ORF YML112W 11.42 0.95 1 116.2953 1 YML112W CTK3 SGDID:S000004580,Gamma subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing, Chr XIII from 45063-45953, Verified ORF YGR159C 20.229 1.00 122 8431.2181 1 YGR159C NSR1 SGDID:S000003391,Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis, Chr VII from 807661-806417, reverse complement, Verified ORF YDR270W 31.589 0.72 4 127.4563 1 YDR270W CCC2 SGDID:S000002678,Cu(+2)-transporting P-type ATPase, required for export of copper from the cytosol into an extracytosolic compartment; has similarity to human proteins involved in Menkes and Wilsons diseases, Chr IV from 1005671-1008685, Verified ORF YDR285W 44.03 1.00 14 444.5127 1 YDR285W ZIP1 SGDID:S000002693,Transverse filament protein of the synaptonemal complex; required for normal levels of meiotic recombination and pairing between homologous chromosome during meiosis; potential Cdc28p substrate, Chr IV from 1032432-1035059, Verified ORF YGR285C 19.079 1.00 136 9965.2503 1 YGR285C ZUO1 SGDID:S000003517,Cytosolic ribosome-associated chaperone that acts, together with Ssz1p and the Ssb proteins, as a chaperone for nascent polypeptide chains; contains a DnaJ domain and functions as a J-protein partner for Ssb1p and Ssb2p, Chr VII from 1063159-1061858, reverse complement, Verified ORF YOR098C 37.626 1.00 9 334.3946 1 YOR098C NUP1 SGDID:S000005624,Nuclear pore complex (NPC) subunit, involved in protein import\export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; potential Cdc28p substrate, Chr XV from 511179-507949, reverse complement, Verified ORF YIL026C 38.03 0.68 3 74.9909 1 YIL026C IRR1 SGDID:S000001288,Subunit of the cohesin complex, which is required for sister chromatid cohesion during mitosis and meiosis and interacts with centromeres and chromosome arms, essential for viability, Chr IX from 307927-304475, reverse complement, Verified ORF YML017W 25.23 0.81 12 538.5845 1 YML017W PSP2 SGDID:S000004479,Asn rich cytoplasmic protein that contains RGG motifs; high-copy suppressor of group II intron-splicing defects of a mutation in MRS2 and of a conditional mutation in POL1 (DNA polymerase alpha); possible role in mitochondrial mRNA splicing, Chr XIII from 236588-236591,236954-238731, Verified ORF YJR073C 5.76 0.67 1 162.6137 1 YJR073C OPI3 SGDID:S000003834,Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), catalyzes the last two steps in phosphatidylcholine biosynthesis, Chr X from 572850-572230, reverse complement, Verified ORF YEL013W 17.409 1.00 7 562.1201 1 YEL013W VAC8 SGDID:S000000739,Phosphorylated vacuolar membrane protein that interacts with Atg13p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway; interacts with Nvj1p to form nucleus-vacuole junctions, Chr V from 128825-130561, Verified ORF YMR128W 58.165 0.98 4 94.2169 1 YMR128W ECM16 SGDID:S000004735,Essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP, predominantly nucleolar in distribution, required for 18S rRNA synthesis, Chr XIII from 523695-527498, Verified ORF YNL087W 52.48 1.00 16 426.2172 1 YNL087W TCB2 SGDID:S000005031,Bud-specific protein with a potential role in membrane trafficking; GFP-fusion protein migrates from the cell surface to intracellular vesicles near vacuole; contains 3 calcium and lipid binding domains; mRNA is targeted to the bud via the mRNA transport system involving She2p, Chr XIV from 462413-465949, Verified ORF YGR134W 48.98 1.00 6 171.2526 1 YGR134W CAF130 SGDID:S000003366,Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation, Chr VII from 757775-761143, Verified ORF YJL177W 8.07 0.99 2 343.0019 1 YJL177W RPL17B SGDID:S000003713,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Ap and has similarity to E. coli L22 and rat L17 ribosomal proteins, Chr X from 90784-91092,91410-91655, Verified ORF YDR502C 15.34 1.00 157 14308.009 1 YDR502C SAM2 SGDID:S000002910,S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p), Chr IV from 1454456-1453302, reverse complement, Verified ORF YGL037C 7.529 1.00 13 2413.8538 1 YGL037C PNC1 SGDID:S000003005,Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span, Chr VII from 427953-427303, reverse complement, Verified ORF YGL040C 12.098 1.00 12 1386.6682 1 YGL040C HEM2 SGDID:S000003008,Delta-aminolevulinate dehydratase, a homo-octameric enzyme, catalyzes the conversion of delta-aminolevulinic acid to porphobilinogen, the second step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus, Chr VII from 420561-419533, reverse complement, Verified ORF YOR259C 20.03 1.00 29 2024.0533 1 YOR259C RPT4 SGDID:S000005785,One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for spindle pole body duplication; localized mainly to the nucleus throughout the cell cycle, Chr XV from 813708-812395, reverse complement, Verified ORF YBL041W 10.73 1.00 16 2084.6117 1 YBL041W PRE7 SGDID:S000000137,20S proteasome beta-type subunit, Chr II from 141250-141975, Verified ORF YLR227W-B 58.14 0.99 7 166.6338 2 YLR227W-B,YPR158C-D YLR227W-B SGDID:S000007376,TyB Gag-Pol protein; proteolytically processed to make the Gag, RT, PR, and IN proteins that are required for retrotransposition, Chr XII from 593440-594744,594746-598708, transposable_element_gene YEL055C 49.886 1.00 48 1345.1399 1 YEL055C POL5 SGDID:S000000781,Protein with sequence similarity to the human MybBP1A and weak sequence similar to B-type DNA polymerases, not required for chromosomal DNA replication; required for the synthesis of rRNA, Chr V from 51539-48471, reverse complement, Verified ORF YNL009W 28.635 0.88 5 214.8129 1 YNL009W IDP3 SGDID:S000004954,Peroxisomal NADP-dependent isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate with the formation of NADP(H+), required for growth on unsaturated fatty acids, Chr XIV from 614822-616084, Verified ORF YGL030W 6.1 1.00 108 24751.3466 1 YGL030W RPL30 SGDID:S000002998,Protein component of the large (60S) ribosomal subunit, has similarity to rat L30 ribosomal protein; involved in pre-rRNA processing in the nucleolus; autoregulates splicing of its transcript, Chr VII from 439096-439098,439329-439643, Verified ORF YJR076C 13.48 1.00 11 1140.7952 1 YJR076C CDC11 SGDID:S000003837,Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM, Chr X from 576516-575269, reverse complement, Verified ORF YKL005C 26.868 0.70 3 109.2669 1 YKL005C BYE1 SGDID:S000001488,Negative regulator of transcription elongation, contains a TFIIS-like domain and a PHD finger, multicopy suppressor of temperature-sensitive ess1 mutations, probably binds RNA polymerase II large subunit, Chr XI from 434520-432736, reverse complement, Verified ORF YPR183W 11.168 1.00 82 10264.6314 1 YPR183W DPM1 SGDID:S000006387,Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane, catalyzes the formation of Dol-P-Man from Dol-P and GDP-Man; required for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and protein glycosylation, Chr XVI from 900751-901554, Verified ORF YOR021C 16.31 1.00 11 942.8522 1 YOR021C YOR021C SGDID:S000005547,Hypothetical protein, Chr XV from 373439-372798, reverse complement, Uncharacterized ORF YOR112W 34.51 0.81 1 32.8129 1 YOR112W YOR112W SGDID:S000005638,Hypothetical protein, Chr XV from 531509-533794, Uncharacterized ORF YIL079C 13.05 0.68 2 145.6911 1 YIL079C AIR1 SGDID:S000001341,RING finger protein that interacts with the arginine methyltransferase Hmt1p to regulate methylation of Npl3p, which modulates Npl3p function in mRNA processing and export; has similarity to Air2p, Chr IX from 212002-210920, reverse complement, Verified ORF YDR177W 7.47 0.97 10 1815.3319 1 YDR177W UBC1 SGDID:S000002584,Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal proteins; plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD); component of the cellular stress response, Chr IV from 816875-817522, Verified ORF YOL018C 18.77 0.96 4 286.0038 1 YOL018C TLG2 SGDID:S000005378,Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation, Chr XV from 292075-290882, reverse complement, Verified ORF YGL124C 26.248 0.74 2 78.8261 1 YGL124C MON1 SGDID:S000003092,Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole; associates, as a complex with Ccz1p, with a perivacuolar compartment; potential Cdc28p substrate, Chr VII from 276720-274786, reverse complement, Verified ORF YBR258C 9.27 0.80 5 603.2331 1 YBR258C SHG1 SGDID:S000000462,Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres, Chr II from 730157-729729, reverse complement, Verified ORF YAR002W 32.21 0.89 15 579.4226 1 YAR002W NUP60 SGDID:S000000063,Subunit of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC in a process controlled by the nucleoplasmic concentration of Gsp1p-GTP; potential Cdc28p substrate; involved in telomere maintenance, Chr I from 152259-153878, Verified ORF YPR074C 30.38 1.00 333 15323.6201 1 YPR074C TKL1 SGDID:S000006278,Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids, Chr XVI from 694835-692793, reverse complement, Verified ORF YKL092C 50.752 0.94 4 103.5713 1 YKL092C BUD2 SGDID:S000001575,GTPase activating factor for Rsr1p\Bud1p required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types, Chr XI from 269103-265789, reverse complement, Verified ORF YIL063C 20.999 1.00 18 1198.3365 1 YIL063C YRB2 SGDID:S000001325,Protein of unknown function involved in nuclear processes of the Ran-GTPase cycle; involved in nuclear protein export; contains Ran Binding Domain and FxFG repeats; interacts with Srm1p, GTP-Gsp1p, Rna1p and Crm1p; is not essential, Chr IX from 243741-242758, reverse complement, Verified ORF YLR262C-A 3.92 1.00 6 2139.7847 1 YLR262C-A YLR262C-A SGDID:S000007246,Similar to C. elegans protein, Chr XII from 669664-669470, reverse complement, Uncharacterized ORF YGL253W 28.08 1.00 567 28228.6993 1 YGL253W HXK2 SGDID:S000003222,Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene, Chr VII from 23935-25395, Verified ORF YPL124W 13.72 0.72 5 366.8202 1 YPL124W SPC29 SGDID:S000006045,Inner plaque spindle pole body (SPB) component, links the central plaque component Spc42p to the inner plaque component Spc110p; required for SPB duplication, Chr XVI from 316754-317515, Verified ORF YJR139C 15.82 1.00 182 16083.1021 1 YJR139C HOM6 SGDID:S000003900,Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase), dimeric enzyme that catalyzes the third step in the common pathway for methionine and threonine biosynthesis; enzyme has nucleotide-binding, dimerization and catalytic regions, Chr X from 690440-689361, reverse complement, Verified ORF YDR233C 13.94 1.00 11 1103.1506 1 YDR233C RTN1 SGDID:S000002641,Protein of unknown function; has similarity to mammalian reticulon proteins; member of the RTNLA (reticulon-like A) subfamily, Chr IV from 930353-929466, reverse complement, Verified ORF YOL076W 35.718 0.81 19 602.3603 1 YOL076W MDM20 SGDID:S000005436,Non-catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met; involved in mitochondrial inheritance and actin assembly, Chr XV from 187024-189414, Verified ORF YEL040W 6.52 0.88 23 4339.7811 1 YEL040W UTR2 SGDID:S000000766,Putative glycosidase, glycosylphosphatidylinositol (GPI)-anchored protein localized to the bud neck; has a role in cell wall maintenance, Chr V from 78053-79456, Verified ORF YGR217W 60.78 0.91 4 83.7231 1 YGR217W CCH1 SGDID:S000003449,Voltage-gated calcium channel involved in calcium influx in response to mating pheromones, Chr VII from 924699-930818, Verified ORF YNL250W 72.27 0.95 7 128.6377 1 YNL250W RAD50 SGDID:S000005194,Subunit of MRX complex, with Mre11p and Xrs2p, involved in processing double-strand DNA breaks in vegetative cells, initiation of meiotic DSBs, telomere maintenance, and nonhomologous end joining, Chr XIV from 175411-179349, Verified ORF YDL092W 5.7 0.99 3 728.4277 1 YDL092W SRP14 SGDID:S000002250,Signal recognition particle (SRP) subunit, interacts with the RNA component of SRP to form the Alu domain, which is the region of SRP responsible for arrest of nascent chain elongation during membrane targeting; homolog of mammalian SRP14, Chr IV from 292781-293221, Verified ORF YLR017W 10.72 1.00 8 1043.2781 1 YLR017W MEU1 SGDID:S000004007,Methylthioadenosine phosphorylase (MTAP), catalyzes the initial step in the methionine salvage pathway; affects polyamine biosynthesis through regulation of ornithine decarboxylase (Spe1p) activity; regulates ADH2 gene expression, Chr XII from 177607-178620, Verified ORF YOR096W 9.549 1.00 185 27084.3705 1 YOR096W RPS7A SGDID:S000005622,Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Bp; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins, Chr XV from 505795-505938,506340-506768, Verified ORF YBR029C 12.358 1.00 24 2714.9883 1 YBR029C CDS1 SGDID:S000000233,Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); an enzyme that catalyzes that conversion of CTP + phosphate into diphosphate + CDP-diaclglyerol, a critical step in the synthesis of all major yeast phospholipids, Chr II from 297742-296369, reverse complement, Verified ORF YPR186C 15.83 0.67 8 473.3569 1 YPR186C PZF1 SGDID:S000006390,Transcription factor IIIA (TFIIIA), essential protein with nine C2H2 Zn-fingers, binds the 5S rRNA gene through the zinc finger domain and directs assembly of a multiprotein initiation complex for RNA polymerase III; also binds DNA, Chr XVI from 911018-909729, reverse complement, Verified ORF YDL136W 2.61 1.00 37 19818.2877 2 YDL191W,YDL136W RPL35B SGDID:S000002295,Protein component of the large (60S) ribosomal subunit, identical to Rpl35Ap and has similarity to rat L35 ribosomal protein, Chr IV from 217600-217602,218008-218367, Verified ORF YDL216C 12.83 0.74 1 80.6324 1 YDL216C RRI1 SGDID:S000002375,Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling, Chr IV from 70320-68998, reverse complement, Verified ORF YHR182W 37.77 1.00 10 370.1331 1 YHR182W YHR182W SGDID:S000001225,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and cytoplasm, Chr VIII from 468219-470576, Uncharacterized ORF YGR098C 53.608 0.99 15 387.2592 1 YGR098C ESP1 SGDID:S000003330,Separase with cysteine protease activity (related to caspases) that promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin; inhibited by Pds1p, Chr VII from 687462-682570, reverse complement, Verified ORF YER025W 23.019 1.00 125 7591.5153 1 YER025W GCD11 SGDID:S000000827,Gamma subunit of the translation initiation factor eIF2, involved in the identification of the start codon; binds GTP when forming the ternary complex with GTP and tRNAi-Met, Chr V from 205250-206833, Verified ORF YLR088W 15.97 0.99 3 259.9898 1 YLR088W GAA1 SGDID:S000004078,Subunit of the GPI (glycosylphosphatidylinositol):protein transamidase complex, removes the GPI-anchoring signal and attaches GPI to proteins in the ER, Chr XII from 316108-317952, Verified ORF YHR008C 8.01 1.00 17 2967.0257 1 YHR008C SOD2 SGDID:S000001050,Manganese-containing superoxide dismutase; protects cells against oxygen toxicity, Chr VIII from 123585-122884, reverse complement, Verified ORF YML111W 35.532 0.73 1 28.7215 1 YML111W BUL2 SGDID:S000004579,Component of the Rsp5p E3-ubiquitin ligase complex, involved in intracellular amino acid permease sorting, functions in heat shock element mediated gene expression, essential for growth in stress conditions, functional homolog of BUL1, Chr XIII from 46942-49704, Verified ORF YMR016C 20.93 0.67 2 89.5035 1 YMR016C SOK2 SGDID:S000004618,Nuclear protein that plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway; negatively regulates pseudohyphal differentiation; homologous to several transcription factors, Chr XIII from 305592-303235, reverse complement, Verified ORF YPR149W 4.27 0.88 9 2592.9982 1 YPR149W NCE102 SGDID:S000006353,Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs), Chr XVI from 829914-830435, Verified ORF YNL306W 13.35 0.81 1 84.822 1 YNL306W MRPS18 SGDID:S000005250,Mitochondrial ribosomal protein of the small subunit; essential for viability, unlike most other mitoribosomal proteins, Chr XIV from 58155-58808, Verified ORF YCR024C-A 0.09 0.85 2 26406.5293 1 YCR024C-A PMP1 SGDID:S000000619,Small single-membrane span proteolipid that functions as a regulatory subunit of the plasma membrane H(+)-ATPase Pma1p, forms unique helix and positively charged cytoplasmic domain that is able to specifically segregate phosphatidylserines, Chr III from 163063-162941, reverse complement, Verified ORF YOR056C 10.98 0.99 2 252.097 1 YOR056C NOB1 SGDID:S000005582,Essential nuclear protein involved in proteasome maturation and synthesis of 40S ribosomal subunits; required for cleavage of the 20S pre-rRNA to generate the mature 18S rRNA, Chr XV from 431628-430249, reverse complement, Verified ORF YGL011C 14.21 1.00 13 1278.9518 1 YGL011C SCL1 SGDID:S000002979,Alpha subunit of the 20S core complex of the 26S proteasome involved in the degradation of ubiquitinated substrates; essential for growth; detected in the mitochondria, Chr VII from 475252-474494, reverse complement, Verified ORF YBL017C 57.688 1.00 3 72.701 1 YBL017C PEP1 SGDID:S000000113,Type I transmembrane sorting receptor for multiple vacuolar hydrolases; cycles between the late-Golgi and prevacuolar endosome-like compartments, Chr II from 191586-186847, reverse complement, Verified ORF YBR034C 12.758 1.00 6 657.4664 1 YBR034C HMT1 SGDID:S000000238,Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs, including Npl3p and Hrp1p, thus facilitating nuclear export of these proteins; required for viability of npl3 mutants, Chr II from 305976-304930, reverse complement, Verified ORF YBR133C 27.65 0.99 6 300.3282 1 YBR133C HSL7 SGDID:S000000337,Protein arginine N-methyltransferase that exhibits septin and Hsl1p-dependent bud neck localization and periodic Hsl1p-dependent phosphorylation; required along with Hsl1p for bud neck recruitment, phosphorylation, and degradation of Swe1p, Chr II from 504281-501798, reverse complement, Verified ORF YGL238W 35.02 1.00 20 798.3967 1 YGL238W CSE1 SGDID:S000003207,Nuclear envelope protein that mediates the nuclear export of importin alpha (Srp1p), homolog of metazoan CAS protein, required for accurate chromosome segregation, Chr VII from 49552-52434, Verified ORF YGR229C 15.23 1.00 23 2111.2168 1 YGR229C SMI1 SGDID:S000003461,Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity, Chr VII from 950902-949385, reverse complement, Verified ORF YBL091C 17.02 1.00 5 410.6911 1 YBL091C MAP2 SGDID:S000000187,Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p, Chr II from 48625-47360, reverse complement, Verified ORF YGL205W 37.559 0.94 6 209.9278 1 YGL205W POX1 SGDID:S000003173,Fatty-acyl coenzyme A oxidase, involved in the fatty acid beta-oxidation pathway; localized to the peroxisomal matrix, Chr VII from 108162-110408, Verified ORF YER048C 22.05 1.00 21 1331.4216 1 YER048C CAJ1 SGDID:S000000850,Nuclear type II J heat shock protein of the E. coli dnaJ family, contains a leucine zipper-like motif, binds to non-native substrates for presentation to Ssa3p, may function during protein translocation, assembly and disassembly, Chr V from 248156-246981, reverse complement, Verified ORF YJR119C 24.13 0.77 1 44.6106 1 YJR119C YJR119C SGDID:S000003880,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus, Chr X from 646406-644220, reverse complement, Uncharacterized ORF YGR124W 23.889 1.00 163 9538.8176 1 YGR124W ASN2 SGDID:S000003356,Asparagine synthetase, isozyme of Asn1p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway, Chr VII from 739949-741667, Verified ORF YHR169W 16.5 0.65 1 55.0724 1 YHR169W DBP8 SGDID:S000001212,Putative ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 40S ribosomal subunit, Chr VIII from 442182-443477, Verified ORF YLR300W 13.76 1.00 12 1219.1797 1 YLR300W EXG1 SGDID:S000004291,Major exo-1,3-beta-glucanase of the cell wall, involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes, Chr XII from 728957-730303, Verified ORF YLR321C 11.23 0.99 2 246.4849 1 YLR321C SFH1 SGDID:S000004313,Subunit of the RSC chromatin remodeling complex required for kinetochore function in chromosome segregation; essential gene required for cell cycle progression; phosphorylated in the G1 phase of the cell cycle; Snf5p paralog, Chr XII from 777864-776584, reverse complement, Verified ORF YIL125W 42.745 1.00 54 1766.0921 1 YIL125W KGD1 SGDID:S000001387,Component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA, Chr IX from 122689-125733, Verified ORF YOR350C 28.758 0.96 6 280.0068 1 YOR350C MNE1 SGDID:S000005877,Mitochondrial protein similar to Lucilia illustris mitochondrial cytochrome oxidase, Chr XV from 994852-992861, reverse complement, Verified ORF YOR051C 18.287 1.00 12 917.3682 1 YOR051C YOR051C SGDID:S000005577,Nuclear protein that inhibits replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts, Chr XV from 426086-424848, reverse complement, Uncharacterized ORF YOR270C 28.76 1.00 67 3256.798 1 YOR270C VPH1 SGDID:S000005796,Subunit of vacuolar-ATPase V0 domain, one of two isoforms (Vph1p and Stv1p); Vph1p is located in V-ATPase complexes of the vacuole while Stv1p is located in V-ATPase complexes of the Golgi and endosomes, Chr XV from 830573-828051, reverse complement, Verified ORF YDL173W 11.12 1.00 4 502.875 1 YDL173W YDL173W SGDID:S000002332,Hypothetical protein, Chr IV from 148192-149079, Uncharacterized ORF YPR112C 54.558 1.00 28 717.4712 1 YPR112C MRD1 SGDID:S000006316,Essential conserved protein that associates with 35S precursor rRNA and is required for its initial processing at the A(0)-A(2) cleavage sites, shows partial nucleolar localization, contains five consensus RNA-binding domains, Chr XVI from 751917-749254, reverse complement, Verified ORF YNR038W 29.85 0.98 2 91.7944 1 YNR038W DBP6 SGDID:S000005321,Essential protein involved in ribosome biogenesis; putative ATP-dependent RNA helicase of the DEAD-box protein family, Chr XIV from 695597-697486, Verified ORF YLR304C 29.787 1.00 152 7133.8132 1 YLR304C ACO1 SGDID:S000004295,Aconitase, required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy, Chr XII from 737550-735214, reverse complement, Verified ORF YDL192W 10.47 1.00 85 11349.5111 1 YDL192W ARF1 SGDID:S000002351,ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated formation vesicles in intracellular trafficking within the Golgi; functionally interchangeable with Arf2p, Chr IV from 116322-116867, Verified ORF YDR473C 21.239 0.85 3 167.846 1 YDR473C PRP3 SGDID:S000002881,Splicing factor, component of the U4\U6-U5 snRNP complex, Chr IV from 1405846-1404437, reverse complement, Verified ORF YLR058C 19.61 1.00 164 11691.5251 1 YLR058C SHM2 SGDID:S000004048,Cytosolic serine hydroxymethyltransferase, involved in one-carbon metabolism, Chr XII from 259402-257993, reverse complement, Verified ORF YLR028C 32.638 1.00 54 2312.9973 1 YLR028C ADE16 SGDID:S000004018,Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade17p; ade16 ade17 mutants require adenine and histidine, Chr XII from 201316-199541, reverse complement, Verified ORF YKL178C 10.8 0.98 1 126.8548 1 YKL178C STE3 SGDID:S000001661,Receptor for a factor receptor, transcribed in alpha cells and required for mating by alpha cells, couples to MAP kinase cascade to mediate pheromone response; ligand bound receptors are endocytosed and recycled to the plasma membrane; GPCR, Chr XI from 114632-113220, reverse complement, Verified ORF YDL044C 24.8 0.96 7 378.8109 1 YDL044C MTF2 SGDID:S000002202,Mitochondrial matrix protein that interacts with an N-terminal region of mitochondrial RNA polymerase (Rpo41p) and couples RNA processing and translation to transcription, Chr IV from 375286-373964, reverse complement, Verified ORF YFR053C 27.62 1.00 62 3138.1444 1 YFR053C HXK1 SGDID:S000001949,Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p, Chr VI from 255036-253579, reverse complement, Verified ORF YIL109C 26.52 1.00 47 2477.5889 1 YIL109C SEC24 SGDID:S000001371,Component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat; involved in ER to Golgi transport, cargo selection and autophagy; required for the binding of the Sec13 complex to ER membranes; homologous to Lst1p and Lss1p, Chr IX from 160162-157382, reverse complement, Verified ORF YNL110C 8.46 1.00 15 2478.7105 1 YNL110C NOP15 SGDID:S000005054,Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis; localizes to both nucleolus and cytoplasm, Chr XIV from 418490-417828, reverse complement, Verified ORF YDR148C 21.61 0.99 3 192.135 1 YDR148C KGD2 SGDID:S000002555,Dihydrolipoyl transsuccinylase, a component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes a step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA, Chr IV from 755063-753672, reverse complement, Verified ORF YNL271C 89.759 0.99 12 185.0305 1 YNL271C BNI1 SGDID:S000005215,Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNR1, Chr XIV from 135384-129523, reverse complement, Verified ORF YNL270C 12.47 0.91 1 102.0187 1 YNL270C ALP1 SGDID:S000005214,Basic amino acid transporter, involved in uptake of cationic amino acids, Chr XIV from 137662-135941, reverse complement, Verified ORF YOR001W 30.308 0.99 19 867.6337 1 YOR001W RRP6 SGDID:S000005527,Exonuclease component of the nuclear exosome; contributes to the quality-control system that retains and degrades aberrant mRNAs in the nucleus, Chr XV from 326833-329034, Verified ORF YCR009C 12.879 1.00 12 1302.5788 1 YCR009C RVS161 SGDID:S000000602,Amphiphysin-like lipid raft protein; subunit of a complex (Rvs161p-Rvs167p) that regulates polarization of the actin cytoskeleton, endocytosis, cell polarity, cell fusion and viability following starvation or osmotic stress, Chr III from 131540-130743, reverse complement, Verified ORF YOR207C 44.175 1.00 20 632.9338 1 YOR207C RET1 SGDID:S000005733,Second-largest subunit of RNA polymerase III, which is responsible for the transcription of tRNA and 5S RNA genes, and other low molecular weight RNAs, Chr XV from 733458-730009, reverse complement, Verified ORF YKL040C 11.219 1.00 19 2367.5783 1 YKL040C NFU1 SGDID:S000001523,Protein involved in iron metabolism in mitochondria; similar to NifU, which is a protein required for the maturation of the Fe\S clusters of nitrogenase in nitrogen-fixing bacteria, Chr XI from 361471-360701, reverse complement, Verified ORF YNL157W 6.47 0.88 2 380.2885 1 YNL157W YNL157W SGDID:S000005101,Hypothetical protein, Chr XIV from 340354-340860, Uncharacterized ORF YGL023C 28.09 0.97 5 241.3764 1 YGL023C PIB2 SGDID:S000002991,Protein binding phosphatidylinositol 3-phosphate, involved in telomere-proximal repression of gene expression; similar to Fab1 and Vps27, Chr VII from 452109-450202, reverse complement, Verified ORF YBL066C 42.655 1.00 4 131.0976 1 YBL066C SEF1 SGDID:S000000162,Putative transcription factor, has homolog in Kluyveromyces lactis, Chr II from 100117-96671, reverse complement, Verified ORF YLR091W 13.9 0.97 1 97.5577 1 YLR091W YLR091W SGDID:S000004081,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YLR091W is not an esssential gene, Chr XII from 322298-323179, Uncharacterized ORF YLR087C 104.546 1.00 14 187.2084 1 YLR087C CSF1 SGDID:S000004077,Protein required for fermentation at low temperature, Chr XII from 315732-306856, reverse complement, Verified ORF YAL012W 14.05 1.00 234 23283.2952 1 YAL012W CYS3 SGDID:S000000010,Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine;, Chr I from 130802-131986, Verified ORF YNR051C 17.15 0.67 1 54.6154 1 YNR051C BRE5 SGDID:S000005334,Ubiquitin protease cofactor, forms deubiquitination complex with Ubp3p that coregulates anterograde and retrograde transport between the endoplasmic reticulum and Golgi compartments; null is sensitive to brefeldin A, Chr XIV from 718329-716782, reverse complement, Verified ORF YGL244W 22.75 0.96 3 176.9766 1 YGL244W RTF1 SGDID:S000003213,Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly regulates DNA-binding properties of Spt15p and relative activities of different TATA elements; involved in telomere maintenance, Chr VII from 41498-43174, Verified ORF YJR068W 19.249 0.97 1 70.4479 1 YJR068W RFC2 SGDID:S000003829,Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon, Chr X from 567558-568619, Verified ORF YLR134W 18.26 1.00 66 5052.9857 1 YLR134W PDC5 SGDID:S000004124,Minor isoform of pyruvate decarboxylase, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde, regulation is glucose- and ethanol-dependent, repressed by thiamine, involved in amino acid catabolism, Chr XII from 410724-412415, Verified ORF YDR538W 11.12 0.95 1 119.4328 1 YDR538W PAD1 SGDID:S000002946,Phenylacrylic acid decarboxylase, confers resistance to cinnamic acid, decarboxylates aromatic carboxylic acids to the corresponding vinyl derivatives, Chr IV from 1510892-1511620, Verified ORF YCL035C 6.748 1.00 12 2486.057 1 YCL035C GRX1 SGDID:S000000540,Hydroperoxide and superoxide-radical responsive heat-stable glutathione-dependent disulfide oxidoreductase with active site cysteine pair; protects cells from oxidative damage, Chr III from 61173-60841, reverse complement, Verified ORF YDL168W 8.7 1.00 4 642.7552 1 YDL168W SFA1 SGDID:S000002327,Bifunctional enzyme containing both alcohol dehydrogenase and glutathione-dependent formaldehyde dehydrogenase activities, functions in formaldehyde detoxification and formation of long chain and complex alcohols, regulated by Hog1p-Sko1p, Chr IV from 159605-160765, Verified ORF YPR163C 25.35 1.00 137 7555.2269 1 YPR163C TIF3 SGDID:S000006367,Translation initiation factor eIF-4B, has RNA annealing activity; contains an RNA recognition motif and binds to single-stranded RNA, Chr XVI from 869951-868641, reverse complement, Verified ORF YMR311C 13.45 1.00 15 1559.0996 1 YMR311C GLC8 SGDID:S000004928,Regulatory subunit of protein phosphatase 1 (Glc7p), involved in glycogen metabolism and chromosome segregation; proposed to regulate Glc7p activity via conformational alteration; ortholog of the mammalian protein phosphatase inhibitor 2, Chr XIII from 897602-896913, reverse complement, Verified ORF YHL008C 23.39 0.68 3 121.9283 1 YHL008C YHL008C SGDID:S000001000,Putative protein of unknown function, does not appear to be involved in monocarboxylic acid transport; green fluorescent protein (GFP)-fusion protein localizes to the vacuole, Chr VIII from 94506-92623, reverse complement, Uncharacterized ORF YKR067W 29.939 0.82 7 268.0275 1 YKR067W GPT2 SGDID:S000001775,Glycerol-3-phosphate acyltransferase located in both lipid particles and the ER; involved in the stepwise acylation of glycerol-3-phosphate and dihydroxyacetone, which are intermediate steps in lipid biosynthesis, Chr XI from 567560-569791, Verified ORF YAL019W 44.749 0.98 7 214.3116 1 YAL019W FUN30 SGDID:S000000017,Protein whose overexpression affects chromosome stability, potential Cdc28p substrate; homolog of Snf2p, Chr I from 114920-118315, Verified ORF YDR170C 66.45 1.00 6 126.2295 1 YDR170C SEC7 SGDID:S000002577,Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles, Chr IV from 802219-796190, reverse complement, Verified ORF YDL124W 18.34 1.00 12 914.7171 1 YDL124W YDL124W SGDID:S000002282,NADPH-dependent alpha-keto amide reductase; reduces aromatic alpha-keto amides, aliphatic alpha-keto esters, and aromatic alpha-keto esters, Chr IV from 240259-241197, Verified ORF YIL138C 13.18 1.00 9 954.6232 1 YIL138C TPM2 SGDID:S000001400,Minor isoform of tropomyosin, binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; appears to have distinct and also overlapping functions with Tpm1p, Chr IX from 89715-89230, reverse complement, Verified ORF YOL064C 16.79 1.00 5 416.317 1 YOL064C MET22 SGDID:S000005425,Bisphosphate-3'-nucleotidase, involved in salt tolerance and methionine biogenesis; dephosphorylates 3'-phosphoadenosine-5'-phosphate and 3'-phosphoadenosine-5'-phosphosulfate, intermediates of the sulfate assimilation pathway, Chr XV from 207176-206103, reverse complement, Verified ORF YER091C 41.92 1.00 424 14140.0027 1 YER091C MET6 SGDID:S000000893,Cobalamin-independent methionine synthase, involved in amino acid biosynthesis; requires a minimum of two glutamates on the methyltetrahydrofolate substrate, similar to bacterial metE homologs, Chr V from 342163-339860, reverse complement, Verified ORF YOL092W 3.52 1.00 10 3971.5702 1 YOL092W YOL092W SGDID:S000005452,Hypothetical protein, Chr XV from 144204-145130, Uncharacterized ORF YEL037C 14.09 1.00 30 2976.5636 1 YEL037C RAD23 SGDID:S000000763,Protein with ubiquitin-like N terminus, recognizes and binds damaged DNA (with Rad4p) during nucleotide excision repair; regulates Rad4p levels, subunit of Nuclear Excision Repair Factor 2 (NEF2); homolog of human HR23A and HR23B proteins, Chr V from 82603-81407, reverse complement, Verified ORF YIL062C 8.5 1.00 16 2631.5157 1 YIL062C ARC15 SGDID:S000001324,Subunit of the ARP2\3 complex, which is required for the motility and integrity of cortical actin patches, Chr IX from 244459-243995, reverse complement, Verified ORF YML091C 47.2799999999999 0.88 4 104.0806 1 YML091C RPM2 SGDID:S000004556,Protein component of mitochondrial RNase P, along with the mitochondrially-encoded RNA subunit RPM1; Rnase P removes 5' extensions from tRNA precursors; Rpm2p is also involved in maturation of RPM1 and in translation of mitochondrial mRNAs, Chr XIII from 90731-87123, reverse complement, Verified ORF YAL017W 60.378 0.80 1 18.5232 1 YAL017W PSK1 SGDID:S000000015,One of two (see also PSK2) PAS domain containing S\T protein kinases; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status, Chr I from 120226-124296, Verified ORF YMR129W 55.484 0.99 6 149.6661 1 YMR129W POM152 SGDID:S000004736,Nuclear pore membrane glycoprotein; may be involved in duplication of nuclear pores and nuclear pore complexes during S-phase;, Chr XIII from 527803-531816, Verified ORF YLR153C 21.35 1.00 50 3273.9876 1 YLR153C ACS2 SGDID:S000004143,Acetyl-coA synthetase isoform, required for growth on glucose; expressed under anaerobic conditions, Chr XII from 447576-445525, reverse complement, Verified ORF YOL128C 17.4 0.65 3 156.6715 1 YOL128C YGK3 SGDID:S000005488,Protein kinase related to mammalian glycogen synthase kinases of the GSK-3 family; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation, Chr XV from 79479-78352, reverse complement, Verified ORF YGR184C 60.325 0.99 12 275.3112 1 YGR184C UBR1 SGDID:S000003416,Ubiquitin-protein ligase (E3) that interacts with Rad6p\Ubc2p to ubiquitinate substrates of the N-end rule pathway; binds to the Rpn2p, Rpt1p, and Rpt6p proteins of the 19S particle of the 26S proteasome, Chr VII from 865758-859906, reverse complement, Verified ORF YKL039W 9.26 0.72 1 108.6992 1 YKL039W PTM1 SGDID:S000001522,Protein of unknown function, copurifies with late Golgi vesicles containing the v-SNARE Tlg2p, Chr XI from 362265-363836, Verified ORF YDR218C 22.21 0.81 2 101.9697 1 YDR218C SPR28 SGDID:S000002626,Sporulation-specific homolog of the yeast CDC3\10\11\12 family of bud neck microfilament genes; meiotic septin expressed at high levels during meiotic divisions and ascospore formation, Chr IV from 905048-903777, reverse complement, Verified ORF YKR024C 33.218 0.76 9 287.8641 1 YKR024C DBP7 SGDID:S000001732,Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis, Chr XI from 487015-484787, reverse complement, Verified ORF YCR093W 95.2350000000001 1.00 23 337.6262 1 YCR093W CDC39 SGDID:S000000689,Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor, Chr III from 280114-286440, Verified ORF YBR142W 34.386 1.00 8 325.2469 1 YBR142W MAK5 SGDID:S000000346,Essential nucleolar protein, putative DEAD-box RNA helicase required for maintenance of M1 dsRNA virus; involved in biogenesis of large (60S) ribosomal subunits, Chr II from 528311-530632, Verified ORF YMR300C 17.375 1.00 17 1367.8202 1 YMR300C ADE4 SGDID:S000004915,Phosphoribosylpyrophosphate amidotransferase (PRPPAT; amidophosphoribosyltransferase), catalyzes first step of the 'de novo' purine nucleotide biosynthetic pathway, Chr XIII from 867090-865558, reverse complement, Verified ORF YDL004W 4.16 1.00 15 5040.8391 1 YDL004W ATP16 SGDID:S000002162,Delta subunit of the central stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis, Chr IV from 443026-443508, Verified ORF YMR011W 8.44 1.00 18 2981.501 1 YMR011W HXT2 SGDID:S000004613,High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose, Chr XIII from 288078-289703, Verified ORF YOL150C 5.67 0.99 2 488.1879 1 YOL150C YOL150C SGDID:S000005510,Hypothetical protein, Chr XV from 44783-44472, reverse complement, Dubious ORF YNL127W 45.188 0.99 9 275.6509 1 YNL127W FAR11 SGDID:S000005071,Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far7p, Far8p, Far9p, and Far10p, Chr XIV from 383989-386850, Verified ORF YJR086W 2.66 0.68 3 1072.1447 1 YJR086W STE18 SGDID:S000003846,G protein gamma subunit, forms a dimer with Ste4p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling, Chr X from 585983-586315, Verified ORF YLR008C 4.838 0.99 5 1430.3563 1 YLR008C PAM18 SGDID:S000003998,Constituent of the mitochondrial import motor associated with the presequence translocase, along with Ssc1p, Tim44p, Mge1p, and Pam16p; stimulates the ATPase activity of Ssc1p to drive mitochondrial import; contains a J domain, Chr XII from 166082-165576, reverse complement, Verified ORF YOR188W 48.46 1.00 8 230.787 1 YOR188W MSB1 SGDID:S000005714,Protein involved in positive regulation of both 1,3-beta-glucan synthesis and the Pkc1p-MAPK pathway, potential Cdc28p substrate; multicopy suppressor of temperature-sensitive mutations in CDC24 and CDC42, and of mutations in BEM4, Chr XV from 685768-689181, Verified ORF YCL051W 22.77 0.65 6 239.4453 1 YCL051W LRE1 SGDID:S000000556,Protein involved in control of cell wall structure and stress response; inhibits Cbk1p protein kinase activity; overproduction confers resistance to cell-wall degrading enzymes, Chr III from 35865-37616, Verified ORF YLR418C 15.95 0.66 2 115.6959 1 YLR418C CDC73 SGDID:S000004410,Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p, distinct from Srb-containing Pol II complexes; required for expression of certain genes, modification of some histones, and telomere maintenance, Chr XII from 958092-956911, reverse complement, Verified ORF YMR205C 28.68 1.00 246 11991.151 1 YMR205C PFK2 SGDID:S000004818,Beta subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes, Chr XIII from 674765-671886, reverse complement, Verified ORF YHR024C 17.41 0.81 1 65.0415 1 YHR024C MAS2 SGDID:S000001066,Larger subunit of the mitochondrial processing protease, essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins, Chr VIII from 159185-157737, reverse complement, Verified ORF YKR008W 29.673 0.87 4 163.9542 1 YKR008W RSC4 SGDID:S000001716,One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; found in close proximity to nucleosomal DNA; displaced from the surface of nucleosomal DNA after chromatin remodeling, Chr XI from 451844-453721, Verified ORF YPR089W 21.39 0.65 2 84.9644 1 YPR089W YPR089W SGDID:S000006293,Hypothetical protein, Chr XVI from 713273-715939, Uncharacterized ORF YGR211W 18.62 1.00 10 750.8016 1 YGR211W ZPR1 SGDID:S000003443,Essential protein with two zinc fingers, present in the nucleus of growing cells but relocates to the cytoplasm in starved cells via a process mediated by Cpr1p; binds to translation elongation factor eEF-1 (Tef1p), Chr VII from 915246-916706, Verified ORF YER100W 9.59 1.00 11 1603.537 1 YER100W UBC6 SGDID:S000000902,Ubiquitin-conjugating enzyme involved in ER-associated protein degradation; located at the cytosolic side of the ER membrane; tail region contains a transmembrane segment at the C-terminus; substrate of the ubiquitin-proteasome pathway, Chr V from 359558-360310, Verified ORF YNL131W 6.24 1.00 7 1568.261 1 YNL131W TOM22 SGDID:S000005075,Component of the TOM (translocase of outer membrane) complex responsible for initial import of mitochondrially directed proteins; acts as a receptor for precursor proteins and mediates interaction between the TOM and TIM complexes, Chr XIV from 378769-379227, Verified ORF YFL048C 20.249 1.00 9 621.3607 1 YFL048C EMP47 SGDID:S000001846,Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport, Chr VI from 40180-38843, reverse complement, Verified ORF YBR247C 26.604 1.00 21 1103.5125 1 YBR247C ENP1 SGDID:S000000451,Protein associated with U3 and U14 snoRNAs, required for pre-rRNA processing and 40S ribosomal subunit synthesis; localized in the nucleus and concentrated in the nucleolus, Chr II from 714450-712999, reverse complement, Verified ORF YPR117W 104.927 1.00 15 199.8521 1 YPR117W YPR117W SGDID:S000006321,Hypothetical protein, Chr XVI from 760023-767492, Uncharacterized ORF YLR024C 62.33 1.00 10 224.2889 1 YLR024C UBR2 SGDID:S000004014,Cytoplasmic ubiquitin-protein ligase (E3), Chr XII from 193282-187664, reverse complement, Verified ORF YKR026C 12.068 0.77 3 267.5972 1 YKR026C GCN3 SGDID:S000001734,Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a positive regulator of GCN4 expression, Chr XI from 489298-488381, reverse complement, Verified ORF YMR194W 4.01 1.00 87 30330.5155 2 YMR194W,YPL249C-A RPL36A SGDID:S000004807,N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl36Bp and has similarity to rat L36 ribosomal protein; binds to 5.8 S rRNA, Chr XIII from 651144-651159,651623-651909, Verified ORF YJL172W 16.76 1.00 5 417.0622 1 YJL172W CPS1 SGDID:S000003708,Vacuolar carboxypeptidase yscS; expression is induced under low-nitrogen conditions, Chr X from 97731-99461, Verified ORF YMR215W 20.73 1.00 14 944.134 1 YMR215W GAS3 SGDID:S000004828,Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall, Chr XIII from 696795-698369, Verified ORF YLL024C 27.055 1.00 909 46970.0754 1 YLL024C SSA2 SGDID:S000003947,ATP binding protein involved in protein folding and vacuolar import of proteins; member of heat shock protein 70 (HSP70) family; associated with the chaperonin-containing T-complex; present in the cytoplasm, vacuolar membrane and cell wall, Chr XII from 97484-95565, reverse complement, Verified ORF YCL009C 11.12 1.00 31 3897.2818 1 YCL009C ILV6 SGDID:S000000515,Regulatory subunit of acetolactate synthase, which catalyzes the first step of branched-chain amino acid biosynthesis; enhances activity of the Ilv2p catalytic subunit, localizes to mitochondria, Chr III from 105548-104619, reverse complement, Verified ORF YEL047C 24.096 1.00 34 1972.5993 1 YEL047C YEL047C SGDID:S000000773,Fumurate ReDuctase Soluble, Chr V from 66797-65385, reverse complement, Uncharacterized ORF YKL016C 7.65 1.00 4 730.9765 1 YKL016C ATP7 SGDID:S000001499,Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis, Chr XI from 407632-407108, reverse complement, Verified ORF YKL060C 15.38 1.00 828 75262.5474 1 YKL060C FBA1 SGDID:S000001543,Fructose 1,6-bisphosphate aldolase, a cytosolic enzyme required for glycolysis and gluconeogenesis; catalyzes the conversion of fructose 1,6 bisphosphate into two 3-carbon products: glyceraldehyde-3-phosphate and dihydroxyacetone phosphate, Chr XI from 327131-326052, reverse complement, Verified ORF YPR058W 11 1.00 4 508.3609 1 YPR058W YMC1 SGDID:S000006262,Putative mitochondrial inner membrane transporter, member of the mitochondrial carrier (MCF) family, Chr XVI from 673748-674671, Verified ORF YLR347C 21.9 1.00 45 2872.5877 1 YLR347C KAP95 SGDID:S000004339,Karyopherin beta, forms a dimeric complex with Srp1p (Kap60p) that mediates nuclear import of cargo proteins via a nuclear localization signal (NLS), interacts with nucleoporins to guide transport across the nuclear pore complex, Chr XII from 826412-823827, reverse complement, Verified ORF YMR202W 2.29 1.00 15 9157.1576 1 YMR202W ERG2 SGDID:S000004815,C-8 sterol isomerase, catalyzes the isomerization of the delta-8 double bond to the delta-7 position at an intermediate step in ergosterol biosynthesis, Chr XIII from 667536-668204, Verified ORF YDR159W 54.109 0.94 9 218.5776 1 YDR159W SAC3 SGDID:S000002566,Nuclear pore-associated protein, forms a complex with Thp1p that is involved in transcription and in mRNA export from the nucleus, Chr IV from 771874-775779, Verified ORF YGL019W 7.44 1.00 6 1127.4134 1 YGL019W CKB1 SGDID:S000002987,Beta regulatory subunit of casein kinase 2, a Ser\Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKA2 and CKB2, the many substrates include transcription factors and all RNA polymerases, Chr VII from 458161-458997, Verified ORF YHR172W 39.34 0.99 7 246.2656 1 YHR172W SPC97 SGDID:S000001215,Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque, Chr VIII from 448335-450806, Verified ORF YGL187C 6.31 1.00 8 1772.4155 1 YGL187C COX4 SGDID:S000003155,Subunit IV of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; N-terminal 25 residues of precursor are cleaved during mitochondrial import, Chr VII from 150177-149710, reverse complement, Verified ORF YHR183W 23.94 1.00 252 14715.7129 1 YHR183W GND1 SGDID:S000001226,6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone and adaptation to oxidative stress, Chr VIII from 470960-472429, Verified ORF YIL013C 37.967 0.79 4 116.3551 1 YIL013C PDR11 SGDID:S000001275,Membrane protein of the ATP-binding cassette (ABC) transporter superfamily, involved in multiple drug resistance, mediates sterol uptake when sterol biosynthesis is compromised, regulated by Pdr1p, required for anaerobic growth, Chr IX from 332440-328205, reverse complement, Verified ORF YER144C 19.34 0.80 1 57.828 1 YER144C UBP5 SGDID:S000000946,Putative ubiquitin-specific protease that does not associate with the proteasome, Chr V from 460218-457801, reverse complement, Verified ORF YLR250W 11.667 0.99 8 949.0102 1 YLR250W SSP120 SGDID:S000004240,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern, Chr XII from 640319-641023, Verified ORF YDR485C 32.07 1.00 2 87.1838 1 YDR485C VPS72 SGDID:S000002893,Protein of unknown function, component of the Swr1p complex that incorporates Htz1p into chromatin; required for vacuolar protein sorting, Chr IV from 1427199-1424812, reverse complement, Verified ORF YDR239C 41.075 1.00 22 748.7727 1 YDR239C YDR239C SGDID:S000002647,Hypothetical protein, Chr IV from 943416-941053, reverse complement, Uncharacterized ORF YGR245C 31.118 1.00 18 808.6595 1 YGR245C SDA1 SGDID:S000003477,Highly conserved nuclear protein required for actin cytoskeleton organization and passage through Start, plays a critical role in G1 events, binds Nap1p, also involved in 60S ribosome biogenesis, Chr VII from 982073-979770, reverse complement, Verified ORF YNL136W 19.69 0.97 2 137.7402 1 YNL136W EAF7 SGDID:S000005080,Subunit of the NuA4 histone acetyltransferase complex, which acetylates the N-terminal tails of histones H4 and H2A, Chr XIV from 370370-371647, Verified ORF YML016C 22.63 1.00 24 1482.6259 1 YML016C PPZ1 SGDID:S000004478,Serine\threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance, Chr XIII from 241536-239458, reverse complement, Verified ORF YGR258C 49.09 1.00 15 427.1723 1 YGR258C RAD2 SGDID:S000003490,Single-stranded DNA endonuclease, cleaves single-stranded DNA during nucleotide excision repair to excise damaged DNA; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPG protein, Chr VII from 1010772-1007677, reverse complement, Verified ORF YDL058W 92.93 1.00 9 135.3915 1 YDL058W USO1 SGDID:S000002216,Essential protein involved in intracellular protein transport, coiled-coil protein necessary for transport from ER to Golgi; required for assembly of the ER-to-Golgi SNARE complex, Chr IV from 345665-351037, Verified ORF YPL006W 26.5 0.74 1 39.0382 1 YPL006W NCR1 SGDID:S000005927,Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; glycoprotein and functional orthologue of human Niemann Pick C1 (NPC1) protein, Chr XVI from 544628-548140, Verified ORF YEL058W 22.296 1.00 6 376.209 1 YEL058W PCM1 SGDID:S000000784,Essential N-acetylglucosamine-phosphate mutase, a hexosephosphate mutase involved in the biosynthesis of chitin, Chr V from 43252-44925, Verified ORF YGR181W 5.98 0.99 1 231.4402 1 YGR181W TIM13 SGDID:S000003413,Mitochondrial intermembrane space protein, forms a complex with TIm8p that medates import and insertion of a subset of polytopic inner membrane proteins; may prevent aggregation of incoming proteins in a chaperone-like manner, Chr VII from 858292-858609, Verified ORF YGR070W 43.02 1.00 13 422.4524 1 YGR070W ROM1 SGDID:S000003302,GDP\GTP exchange protein (GEP) for Rho1p; mutations are synthetically lethal with mutations in rom2, which also encodes a GEP, Chr VII from 627810-631277, Verified ORF YBL087C 7.72 1.00 164 29698.2911 2 YBL087C,YER117W RPL23A SGDID:S000000183,Protein component of the large (60S) ribosomal subunit, identical to Rpl23Bp and has similarity to E. coli L14 and rat L23 ribosomal proteins, Chr II from 60735-60694,60189-59818, reverse complement, Verified ORF YER007C-A 11.91 1.00 15 1760.6961 1 YER007C-A YER007C-A SGDID:S000002957,Hypothetical protein, Chr V from 166884-166874,166770-166236, reverse complement, Uncharacterized ORF YLR370C 6.26 0.97 2 433.2437 1 YLR370C ARC18 SGDID:S000004362,Subunit of the ARP2\3 complex, which is required for the motility and integrity of cortical actin patches, Chr XII from 862253-861717, reverse complement, Verified ORF YJL121C 6.208 1.00 21 4729.0346 1 YJL121C RPE1 SGDID:S000003657,D-ribulose-5-phosphate 3-epimerase, catalyzes a reaction in the non-oxidative part of the pentose-phosphate pathway; mutants are sensitive to oxidative stress, Chr X from 191011-190295, reverse complement, Verified ORF YPL212C 28.98 1.00 13 627.1188 1 YPL212C PUS1 SGDID:S000006133,tRNA:pseudouridine synthase, introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA; nuclear protein that appears to be involved in tRNA export; also acts on U2 snRNA, Chr XVI from 153148-151514, reverse complement, Verified ORF YPL181W 16.17 0.92 1 79.5394 1 YPL181W CTI6 SGDID:S000006102,Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recruiting the SAGA complex to the repressed promoter; contains a PHD finger domain, Chr XVI from 203420-204940, Verified ORF YOL077C 10.75 1.00 23 2991.0542 1 YOL077C BRX1 SGDID:S000005437,Nucleolar protein, constituent of 66S pre-ribosomal particles; depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits; possesses a sigma(70)-like RNA-binding motif, Chr XV from 186723-185848, reverse complement, Verified ORF YOR075W 13.02 0.88 9 850.3918 1 YOR075W UFE1 SGDID:S000005601,t-SNARE required for ER membrane fusion and vesicular traffic, integral membrane protein that constitutes with Sec20p and Use1p the trimeric acceptor for R\v-SNAREs on Golgi-derived vesicles at the ER; part of Dsl1p complex, Chr XV from 468214-469254, Verified ORF YOR220W 12.63 1.00 3 332.0647 1 YOR220W YOR220W SGDID:S000005746,protein that interacts genetically with the Pat1 mRNA-decapping factor, Chr XV from 755329-756126, Uncharacterized ORF YLR100W 17.59 1.00 10 794.7656 1 YLR100W ERG27 SGDID:S000004090,3-keto sterol reductase, catalyzes the last of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants are sterol auxotrophs, Chr XII from 341811-342854, Verified ORF YJL201W 22.56 0.99 6 368.0885 1 YJL201W ECM25 SGDID:S000003737,Non-essential protein of unknown function; promoter contains a consensus binding sequence for factor Abf1p, Chr X from 54379-56178, Verified ORF YMR083W 14.627 1.00 10 955.7617 1 YMR083W ADH3 SGDID:S000004688,Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production, Chr XIII from 434787-435914, Verified ORF YGR086C 12.38 1.00 72 8130.4908 1 YGR086C PIL1 SGDID:S000003318,Integral membrane protein that along with Lsp1p is a primary component of eisosomes, large immobile patch structures at the cell cortex associated with endocytosis; null mutants show activation of Pkc1p\Ypk1p stress resistance pathways, Chr VII from 650621-649602, reverse complement, Verified ORF YMR098C 31.21 0.78 2 69.8772 1 YMR098C YMR098C SGDID:S000004704,Hypothetical protein, Chr XIII from 462608-460770, reverse complement, Uncharacterized ORF YHR205W 18.48 0.99 3 224.6774 1 YHR205W SCH9 SGDID:S000001248,Protein kinase that regulates signal transduction activity and G1 progression, controls cAPK activity, required for nitrogen activation of the FGM pathway, involved in life span regulation, homologous to mammalian Akt\PKB, Chr VIII from 509363-511837, Verified ORF YNL262W 88.8360000000001 1.00 10 157.3678 1 YNL262W POL2 SGDID:S000005206,Catalytic subunit of DNA polymerase epsilon, one of the major chromosomal DNA replication polymerases characterized by processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair, Chr XIV from 148213-154881, Verified ORF YCR069W 15.19 0.88 2 161.9794 1 YCR069W CPR4 SGDID:S000000665,Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway, Chr III from 239051-240007, Verified ORF YGL106W 12.55 1.00 62 6906.4182 1 YGL106W MLC1 SGDID:S000003074,Essential light chain for myosin Myo2p; may stabilize Myo2p by binding to the neck region; may interact with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition, Chr VII from 306563-307012, Verified ORF YGR281W 61.627 0.99 16 359.3263 1 YGR281W YOR1 SGDID:S000003513,Plasma membrane transporter of the ATP-binding cassette (ABC) family, mediates export of many different organic anions including oligomycin, Chr VII from 1052830-1057263, Verified ORF YPL245W 21.468 0.99 2 128.9372 1 YPL245W YPL245W SGDID:S000006166,Hypothetical protein, Chr XVI from 85586-86950, Uncharacterized ORF YGR118W 4.906 1.00 55 15672.5642 2 YPR132W,YGR118W RPS23A SGDID:S000003350,Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Bp and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal, Chr VII from 726978-727042,727363-727735, Verified ORF YPR104C 41.5 1.00 18 606.3582 1 YPR104C FHL1 SGDID:S000006308,Putative transcriptional regulator with similarity to DNA-binding domain of Drosophila forkhead; required for rRNA processing, Chr XVI from 736431-733621, reverse complement, Verified ORF YDR369C 38.61 1.00 7 253.4563 1 YDR369C XRS2 SGDID:S000002777,Protein required for DNA repair; component of the Mre11 complex, which is involved in double strand breaks, meiotic recombination, telomere maintenance, and checkpoint signaling, Chr IV from 1217572-1215008, reverse complement, Verified ORF YLR241W 21.569 0.99 3 192.5002 1 YLR241W YLR241W SGDID:S000004231,Hypothetical protein, Chr XII from 620475-622823, Uncharacterized ORF YOR069W 32.01 0.87 5 189.9802 1 YOR069W VPS5 SGDID:S000005595,Nexin-1 homolog required for localizing membrane proteins from a prevacuolar\late endosomal compartment back to the late Golgi apparatus; structural component of the retromer membrane coat complex; forms a retromer subcomplex with Vps17p, Chr XV from 453770-455797, Verified ORF YKL182W 78.876 1.00 462 8188.4558 1 YKL182W FAS1 SGDID:S000001665,Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities, Chr XI from 100676-106831, Verified ORF YDL065C 21.53 1.00 3 194.7969 1 YDL065C PEX19 SGDID:S000002223,Chaperone and import receptor for newly-synthesized class I peroxisomal membrane proteins (PMPs), binds PMPs in the cytoplasm and delivers them to the peroxisome for subsequent insertion into the peroxisomal membrane, Chr IV from 337277-336249, reverse complement, Verified ORF YIR006C 39.56 1.00 12 424.0625 1 YIR006C PAN1 SGDID:S000001445,Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p, associates with actin patches on the cell cortex; promotes protein-protein interactions essential for endocytosis; previously thought to be a subunit of poly(A) ribonuclease, Chr IX from 369905-365463, reverse complement, Verified ORF YOR119C 18.466 0.85 2 128.7007 1 YOR119C RIO1 SGDID:S000005645,Essential serine kinase involved in cell cycle progression and processing of the 20S pre-rRNA into mature 18S rRNA, Chr XV from 550247-548793, reverse complement, Verified ORF YER090W 23.09 1.00 55 3329.9956 1 YER090W TRP2 SGDID:S000000892,Anthranilate synthase, catalyzes the initial step of tryptophan biosynthesis, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp3p, Chr V from 337945-339468, Verified ORF YIR018W 10.26 0.97 6 793.0134 1 YIR018W YAP5 SGDID:S000001457,Basic leucine zipper (bZIP) transcription factor, Chr IX from 384606-385343, Verified ORF YDR292C 32.288 1.00 3 129.8927 1 YDR292C SRP101 SGDID:S000002700,Signal recognition particle (SRP) receptor - alpha subunit; contain GTPase domains; involved in SRP-dependent protein targeting; interacts with SRP102p, Chr IV from 1045007-1043142, reverse complement, Verified ORF YOL127W 7.67 1.00 145 26428.8064 1 YOL127W RPL25 SGDID:S000005487,Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit, has similarity to E. coli L23 and rat L23a ribosomal proteins; binds to 26S rRNA via a conserved C-terminal motif, Chr XV from 80348-80360,80775-81190, Verified ORF YFL027C 18.11 0.67 3 155.1609 1 YFL027C GYP8 SGDID:S000001867,GTPase-activating protein for yeast Rab family members; Ypt1p is the preferred in vitro substrate but also acts on Sec4p, Ypt31p and Ypt32p; involved in the regulation of ER to Golgi vesicle transport, Chr VI from 81910-80417, reverse complement, Verified ORF YLR380W 17.31 1.00 9 726.8593 1 YLR380W CSR1 SGDID:S000004372,Phosphatidylinositol transfer protein with a potential role in lipid turnover; interacts specifically with thioredoxin peroxidase (Tsa2p) and may have a role in oxidative stress resistance, Chr XII from 878282-879508, Verified ORF YOR124C 51.499 0.93 6 151.4747 1 YOR124C UBP2 SGDID:S000005650,Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, cleaves at the C terminus of ubiquitin fusions; capable of cleaving polyubiquitin and possesses isopeptidase activity, Chr XV from 558643-554825, reverse complement, Verified ORF YOR257W 9.843 1.00 2 284.0582 1 YOR257W CDC31 SGDID:S000005783,Component of the spindle pole body (SPB) half-bridge, required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; interacts with Kar1p, Chr XV from 811008-811493, Verified ORF YJR045C 29.69 1.00 289 13607.9453 1 YJR045C SSC1 SGDID:S000003806,Mitochondrial matrix ATPase that is a subunit of the presequence translocase-associated protein import motor (PAM); involved in protein translocation into the matrix and protein folding; member of the heat shock protein 70 (HSP70) family, Chr X from 521517-519553, reverse complement, Verified ORF YGR169C-A 4.28 0.78 6 1528.6462 1 YGR169C-A YGR169C-A SGDID:S000028521,Putative protein of unknown function, Chr VII from 836670-836392, reverse complement, Uncharacterized ORF YBL023C 46.369 1.00 10 301.4929 1 YBL023C MCM2 SGDID:S000000119,Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex, Chr II from 177529-174923, reverse complement, Verified ORF YHR163W 14.219 1.00 13 1278.1423 1 YHR163W SOL3 SGDID:S000001206,6-phosphogluconolactonase, catalyzes the second step of the pentose phosphate pathway; weak multicopy suppressor of los1-1 mutation; homologous to Sol2p and Sol1p, Chr VIII from 423726-424475, Verified ORF YEL009C-A 5.19 0.86 2 463.3039 1 YEL009C-A YEL009C-A SGDID:S000028741,Questionable ORF from MIPS, Chr V from 136778-136371, reverse complement, Dubious ORF YDL236W 16.78 1.00 20 1666.2607 1 YDL236W PHO13 SGDID:S000002395,Alkaline phosphatase specific for p-nitrophenyl phosphate, involved in dephosphorylation of histone II-A and casein, Chr IV from 32296-33234, Verified ORF YDR127W 67.736 1.00 52 1073.2198 1 YDR127W ARO1 SGDID:S000002534,Pentafunctional arom protein, catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids, Chr IV from 704481-709247, Verified ORF YJL042W 55.596 0.96 7 168.9781 1 YJL042W MHP1 SGDID:S000003578,Microtubule-associated protein involved in assembly and stabilization of microtubules; overproduction results in cell cycle arrest at G2 phase; similar to Drosophila protein MAP and to mammalian MAP4 proteins, Chr X from 361166-365362, Verified ORF YIL052C 2.15 1.00 15 9753.4376 1 YIL052C RPL34B SGDID:S000001314,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Ap and has similarity to rat L34 ribosomal protein, Chr IX from 257061-257025,256552-256224, reverse complement, Verified ORF YPR075C 10.76 0.73 9 853.607 1 YPR075C OPY2 SGDID:S000006279,Protein of unknown function, overproduction blocks cell cycle arrest in the presence of mating pheromone, Chr XVI from 696816-695734, reverse complement, Verified ORF YDR444W 30.17 0.96 1 44.4836 1 YDR444W YDR444W SGDID:S000002852,Hypothetical protein, Chr IV from 1350282-1352345, Uncharacterized ORF YOL017W 18.07 0.92 2 142.3523 1 YOL017W ESC8 SGDID:S000005377,Protein involved in telomeric and mating-type locus silencing, interacts with Sir2p and also interacts with the Gal11p, which is a component of the RNA pol II mediator complex, Chr XV from 292530-294674, Verified ORF YNL059C 30.16 0.99 5 229.445 1 YNL059C ARP5 SGDID:S000005004,Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes, Chr XIV from 514936-512669, reverse complement, Verified ORF YLR033W 25.768 1.00 6 325.5183 1 YLR033W RSC58 SGDID:S000004023,Remodels the structure of chromatin complex 58KDa subunit; Chromatin Remodeling Complex subunit, Chr XII from 208762-210270, Verified ORF YJR033C 61.03 0.99 10 226.7758 1 YJR033C RAV1 SGDID:S000003794,Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzyme; required for transport between the early and late endosome\PVC and for localization of TGN membrane proteins; potential Cdc28p substrate, Chr X from 496366-492293, reverse complement, Verified ORF YMR253C 7.46 0.92 1 172.4066 1 YMR253C YMR253C SGDID:S000004866,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern, Chr XIII from 777189-775945, reverse complement, Uncharacterized ORF YNL175C 23.6 1.00 4 236.9479 1 YNL175C NOP13 SGDID:S000005119,Protein of unknown function, localizes to the nucleolus and nucleoplasm; contains an RNA recognition motif (RRM) and has similarity to Nop12p, which is required for processing of pre-18S rRNA, Chr XIV from 308614-307403, reverse complement, Verified ORF YMR303C 11.12 1.00 310 38972.8188 1 YMR303C ADH2 SGDID:S000004918,Glucose-repressible alcohol dehydrogenase II, catalyzes the conversion of ethanol to acetaldehyde; involved in the production of certain carboxylate esters; regulated by ADR1, Chr XIII from 874336-873290, reverse complement, Verified ORF YER012W 7.46 1.00 5 936.9924 1 YER012W PRE1 SGDID:S000000814,20S proteasome beta-type subunit; localizes to the nucleus throughout the cell cycle, Chr V from 177834-178430, Verified ORF YOL030W 11.28 1.00 9 1115.4197 1 YOL030W GAS5 SGDID:S000005390,Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall, Chr XV from 268188-269642, Verified ORF YBL098W 17.57 0.79 5 314.2897 1 YBL098W BNA4 SGDID:S000000194,Kynurenine 3-mono oxygenase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway, Chr II from 39142-40524, Verified ORF YJR009C 11.58 1.00 747 90181.3962 1 YJR009C TDH2 SGDID:S000003769,Glyceraldehyde-3-phosphate dehydrogenase, isozyme 2, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall , Chr X from 454596-453598, reverse complement, Verified ORF YIL041W 13.05 1.00 80 8570.0703 1 YIL041W GVP36 SGDID:S000001303,Golgi vesicle protein of unknown function; localizes to both early and late Golgi vesicles, Chr IX from 276524-277504, Uncharacterized ORF YDL130W 2.6 0.99 82 43649.6345 1 YDL130W RPP1B SGDID:S000002288,Ribosomal protein P1 beta, component of the ribosomal stalk, which is involved in interaction of translational elongation factors with ribosome; accumulation is regulated by phosphorylation and interaction with the P2 stalk component, Chr IV from 229906-230019,230321-230527, Verified ORF YLR301W 12 1.00 21 2446.4872 1 YLR301W YLR301W SGDID:S000004292,Hypothetical protein, Chr XII from 730827-731561, Uncharacterized ORF YIL030C 35.96 0.99 5 192.4378 1 YIL030C SSM4 SGDID:S000001292,Ubiquitin-protein ligase of the ER\nuclear envelope, required for degradation of Alpha2p and other proteins containing a Deg1 degradation signal; ssm4 mutation suppresses mRNA instability caused by an rna14 mutation, Chr IX from 300008-296049, reverse complement, Verified ORF YDL221W 3.6 0.67 3 780.5459 1 YDL221W YDL221W SGDID:S000002380,Hypothetical protein; open reading frame overlaps 3' end of essential CDC13 gene encoding a telomere capping protein, Chr IV from 62012-62563, Dubious ORF YGL041W-A 3.59 0.99 2 771.0377 1 YGL041W-A YGL041W-A SGDID:S000028826,Identified by expression profiling and mass spectrometry, Chr VII from 419047-419295, Dubious ORF YER069W 36.55 0.93 8 284.5708 1 YER069W ARG5,Protein that is processed in the mitochondrion to yield acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase, which catalyze the 2nd and 3rd steps in arginine biosynthesis; enzymes form a complex with Arg2p,6 SGDID:S000000871, Chr V from 295408-297999, Verified ORF YKL027W 22.348 0.94 3 176.4068 1 YKL027W YKL027W SGDID:S000001510,Protein of unknown function, localized to the mitochondrial outer membrane, Chr XI from 387205-388548, Verified ORF YOR343W-B 63.64 0.90 12 237.2457 1 YOR343W-B YOR343W-B SGDID:S000007356,TyB Gag-Pol protein; proteolytically processed to make the Gag, RT, PR, and IN proteins that are required for retrotransposition, Chr XV from 970575-971868,971870-975888, transposable_element_gene YCR053W 27.04 1.00 170 8789.1554 1 YCR053W THR4 SGDID:S000000649,Threonine synthase, conserved protein that catalyzes formation of threonine from 0-phosphohomoserine; expression is regulated by the GCN4-mediated general amino acid control pathway, Chr III from 216693-218237, Verified ORF YDR458C 33.819 0.99 33 1350.4959 1 YDR458C YDR458C SGDID:S000002866,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery, Chr IV from 1382038-1380047, reverse complement, Uncharacterized ORF YPL202C 15.43 0.83 4 300.7994 1 YPL202C AFT2 SGDID:S000006123,Iron-regulated transcriptional activator, required for iron homeostasis and resistance to oxidative stress; similar to Aft1p, Chr XVI from 169337-168087, reverse complement, Verified ORF YDL001W 16.53 0.92 8 622.4577 1 YDL001W RMD1 SGDID:S000002159,Cytoplasmic protein required for sporulation, Chr IV from 447981-449273, Verified ORF YPR010C 41.39 1.00 53 1790.1332 1 YPR010C RPA135 SGDID:S000006214,RNA polymerase I subunit A135, Chr XVI from 581193-577582, reverse complement, Verified ORF YOR346W 51.529 0.99 8 214.8712 1 YOR346W REV1 SGDID:S000005873,Deoxycytidyl transferase, forms a complex with the subunits of DNA polymerase zeta, Rev3p and Rev7p; involved in repair of abasic sites in damaged DNA, Chr XV from 981825-984782, Verified ORF YOL145C 51.227 1.00 10 272.9015 1 YOL145C CTR9 SGDID:S000005505,Component of the Paf1p complex, which is a large complex that binds to and modulates the activity of RNA polymerase II and is required for expression of a subset of genes, including cyclin genes; contains TPR repeats, Chr XV from 52787-49554, reverse complement, Verified ORF YBR056W 22.58 1.00 10 619.1287 1 YBR056W YBR056W SGDID:S000000260,Hypothetical protein, Chr II from 347877-349382, Uncharacterized ORF YLR114C 30.49 0.98 9 404.4045 1 YLR114C YLR114C SGDID:S000004104,Mutation is syntheticly lethal with apl2 vps1 double mutant, Chr XII from 377239-374945, reverse complement, Uncharacterized ORF YJR072C 14.01 0.98 3 293.3689 1 YJR072C NPA3 SGDID:S000003833,Cytoplasmic protein required for cell viability, identified by association with pre-ribosomal particles, Chr X from 572039-570882, reverse complement, Verified ORF YOR279C 10.88 0.65 1 83.5197 1 YOR279C RFM1 SGDID:S000005805,DNA-binding protein required for vegetative repression of middle sporulation genes; specificity factor that directs the Hst1p histone deacetylase to some of the promoters regulated by Sum1p; involved in telomere maintenance, Chr XV from 844629-843697, reverse complement, Verified ORF YMR305C 9.77 0.97 2 277.5952 1 YMR305C SCW10 SGDID:S000004921,Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on mutant phenotype and its regulation by Ste12p, Chr XIII from 880231-879062, reverse complement, Verified ORF YKR065C 6.13 0.99 1 225.7769 1 YKR065C PAM17 SGDID:S000001773,Presequence translocase-associated motor subunit, required for stable complex formation between cochaperones Pam16p and Pam18p, promotes association of Pam16p-Pam18p with the presequence translocase, Chr XI from 565534-564941, reverse complement, Verified ORF YOR310C 27.937 1.00 160 8006.5446 1 YOR310C NOP58 SGDID:S000005837,Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA, Chr XV from 898357-896822, reverse complement, Verified ORF YOR294W 8.379 1.00 22 3670.5859 1 YOR294W RRS1 SGDID:S000005820,Essential protein that binds ribosomal protein L11 and is required for nuclear export of the 60S pre-ribosomal subunit during ribosome biogenesis; mouse homolog shows altered expression in Huntington's disease model mice, Chr XV from 868339-868950, Verified ORF YOR273C 16.35 0.85 2 145.357 1 YOR273C TPO4 SGDID:S000005799,Polyamine transport protein, recognizes spermine, putrescine, and spermidine; localizes to the plasma membrane; member of the major facilitator superfamily, Chr XV from 836430-834451, reverse complement, Verified ORF YLR248W 18.75 0.93 1 69.3404 1 YLR248W RCK2 SGDID:S000004238,Protein kinase involved in the response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations, Chr XII from 634254-636086, Verified ORF YMR038C 7.76 1.00 14 2522.1518 1 YMR038C CCS1 SGDID:S000004641,Copper chaperone for superoxide dismutase Sod1p, involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within the N-terminal portion is involved in insertion of copper into Sod1p under conditions of copper deprivation, Chr XIII from 348259-347510, reverse complement, Verified ORF YLR398C 62.77 0.69 2 30.7349 1 YLR398C SKI2 SGDID:S000004390,Putative RNA helicase, involved in exosome mediated 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs; forms complex with Ski3p and Ski8p; required for repressing propagation of dsRNA viruses, Chr XII from 919019-915156, reverse complement, Verified ORF YEL022W 56.297 1.00 14 347.6543 1 YEL022W GEA2 SGDID:S000000748,Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; similar to but not functionally redundant with Gea1p, Chr V from 111421-115800, Verified ORF YLR309C 63.058 0.93 5 103.0902 1 YLR309C IMH1 SGDID:S000004300,Protein involved in vesicular transport, mediates transport between an endosomal compartment and the Golgi, contains a Golgi-localization (GRIP) domain that interacts with activated Arl1p-GTP to localize Imh1p to the Golgi, Chr XII from 751771-749036, reverse complement, Verified ORF YGL012W 10.62 1.00 11 1448.015 1 YGL012W ERG4 SGDID:S000002980,C-24(28) sterol reductase, catalyzes the final step in ergosterol biosynthesis; mutants are viable, but lack ergosterol, Chr VII from 472860-474281, Verified ORF YER023W 6.02 1.00 5 1161.1235 1 YER023W PRO3 SGDID:S000000825,Delta 1-pyrroline-5-carboxylate reductase, catalyzes the last step in proline biosynthesis, Chr V from 201075-201935, Verified ORF YFR044C 24.22 1.00 169 9754.7799 1 YFR044C YFR044C SGDID:S000001940,Putative protein of unknown function; gene expression regulated by Abf1p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and mitochondrion; YFR044C is not an essential gene, Chr VI from 241424-239979, reverse complement, Uncharacterized ORF YML024W 7.69 1.00 222 40358.1776 2 YML024W,YDR447C RPS17A SGDID:S000004486,Ribosomal protein 51 (rp51) of the small (40s) subunit; nearly identical to Rps17Bp and has similarity to rat S17 ribosomal protein, Chr XIII from 225889-225891,226290-226697, Verified ORF YIL129C 96.54 1.00 7 101.3667 1 YIL129C TAO3 SGDID:S000001391,Protein involved in cell morphogenesis and proliferation, associated with protein kinase Cbk1p; mutants activate OCH1 transcription, Chr IX from 113237-106107, reverse complement, Verified ORF YHR194W 17.12 0.98 9 720.2275 1 YHR194W MDM31 SGDID:S000001237,Mitochondrial inner membrane protein with similarity to Mdm32p, required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34, Chr VIII from 488657-490396, Verified ORF YJL055W 11.15 1.00 7 877.6635 1 YJL055W YJL055W SGDID:S000003591,Putative protein of unknown function; deletion mutants are sensitive to purine base analogs, 6-hydroxylaminopurine (HAP) and 2-amino-6-hydroxylaminopurine (AHA) and are AHA-hypermutable, Chr X from 333274-334011, Uncharacterized ORF YGL027C 35.91 1.00 17 661.8177 1 YGL027C CWH41 SGDID:S000002995,Processing alpha glucosidase I, ER type II integral membrane N-glycoprotein involved in assembly of cell wall beta 1,6 glucan and asparagine-linked protein glycosylation; also involved in ER protein quality control and sensing of ER stress, Chr VII from 446148-443647, reverse complement, Verified ORF YML028W 11.72 1.00 282 33637.709 1 YML028W TSA1 SGDID:S000004490,Ubiquitous housekeeping thioredoxin peroxidase, reduces reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; mediates redox regulation of the nuclear localization of Yap1p; deletion results in mutator phenotype, Chr XIII from 220138-220728, Verified ORF YJL136C 6.638 1.00 89 18743.8012 1 YJL136C RPS21B SGDID:S000003672,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Bp and has similarity to rat S21 ribosomal protein, Chr X from 157192-157169,156708-156469, reverse complement, Verified ORF YLR423C 28.949 1.00 4 193.1662 1 YLR423C ATG17 SGDID:S000004415,Protein that interacts with and is required for activation of Apg1p protein kinase; involved in autophagy but not in the Cvt (cytoplasm to vacuole targeting) pathway, Chr XII from 973167-971914, reverse complement, Verified ORF YBL076C 58.549 1.00 271 6470.7514 1 YBL076C ILS1 SGDID:S000000172,Cytoplasmic isoleucine-tRNA synthetase, target of the G1-specific inhibitor reveromycin A, Chr II from 84259-81041, reverse complement, Verified ORF YDR245W 16.44 0.68 2 115.649 1 YDR245W MNN10 SGDID:S000002653,Subunit of a Golgi mannosyltransferase complex also containing Anp1p, Mnn9p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; membrane protein of the mannosyltransferase family, Chr IV from 952796-953977, Verified ORF YDR212W 26.12 1.00 40 2140.877 1 YDR212W TCP1 SGDID:S000002620,Alpha subunit of chaperonin-containing T-complex, which mediates protein folding in the cytosol; involved in maintenance of actin cytoskeleton; homolog to Drosophila melanogaster and mouse tailless complex polypeptide, Chr IV from 887229-888908, Verified ORF YKR025W 14.39 0.91 6 530.4406 1 YKR025W RPC37 SGDID:S000001733,RNA polymerase III subunit C37, Chr XI from 487413-488261, Verified ORF YOR103C 3.4 0.99 7 2849.4381 1 YOR103C OST2 SGDID:S000005629,Epsilon subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins, Chr XV from 516842-516450, reverse complement, Verified ORF YBR031W 10.64 1.00 522 68585.7334 1 YBR031W RPL4A SGDID:S000000235,N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl4Bp and has similarity to E. coli L4 and rat L4 ribosomal proteins, Chr II from 300166-301254, Verified ORF YBR225W 35.156 0.99 3 118.1032 1 YBR225W YBR225W SGDID:S000000429,Hypothetical protein, Chr II from 670622-673324, Uncharacterized ORF YOR254C 28.481 1.00 39 1914.3188 1 YOR254C SEC63 SGDID:S000005780,Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p\BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER, Chr XV from 807024-805033, reverse complement, Verified ORF YHR174W 28.489 1.00 2330 114336.1668 1 YHR174W ENO2 SGDID:S000001217,Enolase II, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is induced in response to glucose, Chr VIII from 451327-452640, Verified ORF YLR107W 15.44 0.98 23 2040.852 1 YLR107W REX3 SGDID:S000004097,RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases, Chr XII from 364117-365331, Verified ORF YKL020C 38.688 0.94 6 203.8016 1 YKL020C SPT23 SGDID:S000001503,ER membrane protein involved, with its homolog Mga2p, in regulation of OLE1 transcription; inactive ER form dimerizes and one subunit is then activated by ubiquitin\proteasome-dependent processing followed by nuclear targeting, Chr XI from 401723-398475, reverse complement, Verified ORF YLR441C 12.11 1.00 423 48831.6205 1 YLR441C RPS1A SGDID:S000004433,Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Bp and has similarity to rat S3a ribosomal protein, Chr XII from 1018905-1018138, reverse complement, Verified ORF YMR072W 8.44 1.00 23 3809.6958 1 YMR072W ABF2 SGDID:S000004676,Mitochondrial DNA-binding protein involved in mitochondrial DNA replication and recombination, member of HMG1 DNA-binding protein family; activity may be regulated by protein kinase A phosphorylation, Chr XIII from 411568-412119, Verified ORF YER094C 5.94 1.00 35 8237.3308 1 YER094C PUP3 SGDID:S000000896,Beta subunit of the 20S proteasome involved in ubiquitin-dependent catabolism; human homolog is subunit C10, Chr V from 349342-348725, reverse complement, Verified ORF YGR145W 24.77 1.00 3 169.3168 1 YGR145W ENP2 SGDID:S000003377,Essential nucleolar protein of unknown function; contains WD repeats, interacts with Mpp10p and Bfr2p, and has homology to Spb1p, Chr VII from 781772-783895, Uncharacterized ORF YLR265C 11.13 0.85 6 640.5896 1 YLR265C NEJ1 SGDID:S000004255,Protein involved in regulation of nonhomologous end joining; repressed by MAT heterozygosity; associates with Lif1p and regulates its cellular distribution, Chr XII from 675457-674429, reverse complement, Verified ORF YBL005W 31.497 0.97 4 172.2136 1 YBL005W PDR3 SGDID:S000000101,Transcriptional activator of the pleiotropic drug resistance network, regulates expression of ATP-binding cassette (ABC) transporters through binding to cis-acting sites known as PDREs (PDR responsive elements), Chr II from 217473-220403, Verified ORF YOL027C 27.819 1.00 4 201.0126 1 YOL027C MDM38 SGDID:S000005387,Mitochondrial inner membrane protein, required for K+\H+ exchange and for normal mitochondrial morphology and inheritance; associates with mitochondrial ribosomes; human ortholog Letm1 is implicated in Wolf-Hirschhorn syndrome, Chr XV from 273725-272004, reverse complement, Verified ORF YMR093W 18.32 1.00 10 763.0964 1 YMR093W UTP15 SGDID:S000004699,Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA, Chr XIII from 454014-455555, Verified ORF YIL016W 5.98 0.99 7 1620.0818 1 YIL016W SNL1 SGDID:S000001278,Protein of unknown function proposed to be involved in nuclear pore complex biogenesis and maintenance as well as protein folding; has similarity to the mammalian BAG-1 protein, Chr IX from 321452-321931, Verified ORF YOL143C 4.77 1.00 14 4103.1233 1 YOL143C RIB4 SGDID:S000005503,Lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, also known as DMRL synthase); catalyzes synthesis of immediate precursor to riboflavin, Chr XV from 55103-54594, reverse complement, Verified ORF YER177W 13.36 1.00 183 19149.1518 1 YER177W BMH1 SGDID:S000000979,14-3-3 protein, major isoform; binds proteins and DNA, involved in regulation of many processes including exocytosis and vesicle transport, Ras\MAPK signaling during pseudohyphal development, rapamycin-sensitive signaling, and others, Chr V from 545606-546409, Verified ORF YAL029C 64.456 0.72 4 62.4646 1 YAL029C MYO4 SGDID:S000000027,One of two type V myosins; required for mother-specific HO expression, for the bud tip localization of ASH1 and IST2 mRNA; facilitates growth and orientation of ER tubules along with She3p, Chr I from 92271-87856, reverse complement, Verified ORF YIL108W 26.29 0.98 2 104.2246 1 YIL108W YIL108W SGDID:S000001370,Putative metalloprotease, Chr IX from 160884-162974, Uncharacterized ORF YER063W 9.25 0.96 2 290.1779 1 YER063W THO1 SGDID:S000000865,Protein of unknown function; overproduction suppresses the transcriptional defect caused by an hpr1 mutation, Chr V from 281708-282364, Verified ORF YGR233C 48.887 0.93 5 132.9733 1 YGR233C PHO81 SGDID:S000003465,Cyclin-dependent kinase (CDK) inhibitor, regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; required for derepression of PHO5; transcriptionally regulated by Pho4p and Pho2p, Chr VII from 958213-954677, reverse complement, Verified ORF YDR404C 7.2 0.80 2 310.665 1 YDR404C RPB7 SGDID:S000002812,RNA polymerase II subunit B16; forms two subunit dissociable complex with Rpb4p, Chr IV from 1277161-1276646, reverse complement, Verified ORF YOR058C 41.769 0.84 1 28.1144 1 YOR058C ASE1 SGDID:S000005584,Member of a family of microtubule-associated proteins (MAPs) that function at the mitotic spindle midzone; required for spindle elongation; undergoes cell cycle-regulated degradation by anaphase promoting complex; potential Cdc28p substrate, Chr XV from 436347-433690, reverse complement, Verified ORF YNL049C 32.379 0.93 6 240.9215 1 YNL049C SFB2 SGDID:S000004994,Probable component of COPII coated vesicles that binds to Sec23p; similar to and functionally redundant with Sec24p, but expressed at low levels; involved in ER to Golgi transport and in autophagy, Chr XIV from 537912-535282, reverse complement, Verified ORF YER019W 13.738 0.99 4 402.9735 1 YER019W ISC1 SGDID:S000000821,Inositol phosphosphingolipid phospholipase C, hydrolyzes inositolphosphosphingolipids, activated by phosphatidylserine, cardiolipin, and phosphatidylglycerol, mediates Na+ and Li+ halotolerance, contains a P loop-like domain, Chr V from 192796-194229, Verified ORF YGR166W 24.41 0.90 38 1958.6788 1 YGR166W KRE11 SGDID:S000003398,Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP (transport protein particle) complex, which is involved in the late steps of endoplasmic reticulum to Golgi transport, Chr VII from 830520-832202, Verified ORF YMR302C 43.407 1.00 15 483.0992 1 YMR302C YME2 SGDID:S000004917,Integral inner mitochondrial membrane protein with similarity to exonucleases; mutants exhibit an increased rate of mitochondrial DNA escape, Chr XIII from 872624-870072, reverse complement, Verified ORF YBL104C 35.99 0.98 4 152.2681 1 YBL104C YBL104C SGDID:S000000200,Hypothetical protein, Chr II from 21293-18177, reverse complement, Uncharacterized ORF YDL073W 39.888 1.00 15 525.7192 1 YDL073W YDL073W SGDID:S000002231,Hypothetical protein, Chr IV from 326613-329567, Uncharacterized ORF YNL108C 10.228 0.99 2 270.6321 1 YNL108C YNL108C SGDID:S000005052,Hypothetical protein, Chr XIV from 419828-419016, reverse complement, Uncharacterized ORF YEL042W 17.6 0.99 5 393.1854 1 YEL042W GDA1 SGDID:S000000768,Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-mannose into the Golgi lumen by converting GDP to GMP after mannose is transferred its substrate, Chr V from 73771-75327, Verified ORF YBR084W 44.481 1.00 37 1162.8724 1 YBR084W MIS1 SGDID:S000000288,Mitochondrial C1-tetrahydrofolate synthase, involved in interconversion between different oxidation states of tetrahydrofolate (THF); provides activities of formyl-THF synthetase, methenyl-THF cyclohydrolase, and methylene-THF dehydrogenase, Chr II from 411048-413975, Verified ORF YKL085W 20.42 1.00 77 5271.569 1 YKL085W MDH1 SGDID:S000001568,Mitochondrial malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the tricarboxylic acid (TCA) cycle, Chr XI from 278767-279771, Verified ORF YMR173W 11.88 0.91 3 321.2559 1 YMR173W DDR48 SGDID:S000004784,DNA damage-responsive protein, expression is increased in response to heat-shock stress or treatments that produce DNA lesions; contains multiple repeats of the amino acid sequence NNNDSYGS, Chr XIII from 608688-609980, Verified ORF YKL203C 92.337 1.00 51 772.1458 1 YKL203C TOR2 SGDID:S000001686,PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis, Chr XI from 63360-55936, reverse complement, Verified ORF YHR052W 17.71 1.00 27 2131.3271 1 YHR052W CIC1 SGDID:S000001094,Essential protein that interacts with proteasome components and has a potential role in proteasome substrate specificity; also copurifies with 66S pre-ribosomal particles, Chr VIII from 210842-211972, Verified ORF YKL221W 4.03 0.76 1 263.6413 1 YKL221W MCH2 SGDID:S000001704,Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport, Chr XI from 6108-7529, Verified ORF YNL138W 19.988 1.00 53 3706.9048 1 YNL138W SRV2 SGDID:S000005082,CAP (cyclase-associated protein) subunit of adenylyl cyclase complex; N-terminus binds adenylyl cyclase and facilitates activation by RAS; C-terminus binds ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis, Chr XIV from 366743-368323, Verified ORF YGL173C 69.246 1.00 50 1009.4393 1 YGL173C KEM1 SGDID:S000003141,Evolutionarily-conserved 5'-3' exonuclease component of cytoplasmic processing (P) bodies involved in mRNA decay; plays a role in microtubule-mediated processes, filamentous growth, ribosomal RNA maturation, and telomere maintenance, Chr VII from 180119-175533, reverse complement, Verified ORF YLR311C 3.19 0.89 2 780.0711 1 YLR311C YLR311C SGDID:S000004302,Hypothetical protein, Chr XII from 757614-757267, reverse complement, Dubious ORF YLR355C 25.808 1.00 664 35968.1948 1 YLR355C ILV5 SGDID:S000004347,Acetohydroxyacid reductoisomerase, mitochondrial protein involved in branched-chain amino acid biosynthesis, also required for maintenance of wild-type mitochondrial DNA, Chr XII from 839252-838065, reverse complement, Verified ORF YLR285W 4.118 0.88 4 1194.9816 1 YLR285W NNT1 SGDID:S000004275,Putative nicotinamide N-methyltransferase, has a role in rDNA silencing and in lifespan determination, Chr XII from 707362-708147, Verified ORF YLR039C 37.82 0.72 19 505.6726 1 YLR039C RIC1 SGDID:S000004029,Protein involved in retrograde transport to the cis-Golgi network; forms heterodimer with Rgp1p that acts as a GTP exchange factor for Ypt6p; involved in transcription of rRNA and ribosomal protein genes, Chr XII from 228597-225427, reverse complement, Verified ORF YHL011C 17.4 1.00 11 883.7885 1 YHL011C PRS3 SGDID:S000001003,5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, histidine, and tryptophan biosynthesis; one of a five related enzymes, which are active as heteromultimeric complexes, Chr VIII from 81612-80650, reverse complement, Verified ORF YDR168W 29.71 1.00 18 846.9831 1 YDR168W CDC37 SGDID:S000002575,Essential Hsp90p co-chaperone; necessary for passage through the START phase of the cell cycle, Chr IV from 790325-791845, Verified ORF YLR113W 15.25 1.00 14 1283.4031 1 YLR113W HOG1 SGDID:S000004103,Mitogen-activated protein kinase involved in osmoregulation via three independent osmosensors; mediates the recruitment and activation of RNA Pol II at Hot1p-dependent promoters; localization regulated by Ptp2p and Ptp3p, Chr XII from 371621-372928, Verified ORF YNL308C 30.63 1.00 6 273.8477 1 YNL308C KRI1 SGDID:S000005252,Essential nucleolar protein required for 40S ribosome biogenesis; physically and functionally interacts with Krr1p, Chr XIV from 55896-54121, reverse complement, Verified ORF YIL149C 93.97 0.95 6 84.7989 1 YIL149C MLP2 SGDID:S000001411,Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the nuclear interior; involved in the Tel1p pathway that controls telomere length, Chr IX from 68067-63028, reverse complement, Verified ORF YDR397C 4.91 0.99 2 563.7526 1 YDR397C NCB2 SGDID:S000002805,Beta subunit of the NC2 dimeric histone-fold complex; represses RNA polymerase II transcription through binding to TBP and inhibition of TFIIA and TFIIB; homologous to the Dr1 subunit of the mammalian NC2 (negative cofactor2), Chr IV from 1266890-1266854,1266761-1266358, reverse complement, Verified ORF YOR171C 31.582 0.97 7 300.5626 1 YOR171C LCB4 SGDID:S000005697,Sphingoid long-chain base kinase, responsible for synthesis of long-chain base phosphates, which function as signaling molecules, regulates synthesis of ceramide from exogenous long-chain bases, localizes to the Golgi and late endosomes, Chr XV from 653885-652011, reverse complement, Verified ORF YER088W-B 0.88 0.99 7 11009.1927 1 YER088W-B YER088W-B SGDID:S000028623,Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching, Chr V from 335923-336069, Dubious ORF YLR043C 8.23 1.00 84 14268.6985 1 YLR043C TRX1 SGDID:S000004033,Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against both oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance, Chr XII from 232014-231703, reverse complement, Verified ORF YHR210C 12.419 0.93 5 523.4452 1 YHR210C YHR210C SGDID:S000001253,Hypothetical protein, Chr VIII from 521737-520712, reverse complement, Uncharacterized ORF YCR032W 74.096 0.65 4 49.055 1 YCR032W BPH1 SGDID:S000000628,Protein homologous to human Chediak-Higashi syndrome protein and murine beige gene, which are implicated in disease syndromes due to defective lysosomal trafficking, Chr III from 179516-186019, Verified ORF YBL099W 26.373 1.00 104 5512.8822 1 YBL099W ATP1 SGDID:S000000195,Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis, Chr II from 37050-38687, Verified ORF YGR218W 40.04 1.00 23 803.0427 1 YGR218W CRM1 SGDID:S000003450,Major karyopherin, involved in export of proteins, RNAs, and ribosomal subunits from the nucleus, Chr VII from 932544-935798, Verified ORF YFL007W 76.94 0.92 5 83.5815 1 YFL007W BLM10 SGDID:S000001887,Proteosome activator subunit; found in association with core particles, with and without the 19S regulatory particle; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200, Chr VI from 123474-129905, Verified ORF YDR180W 68.487 0.99 12 242.5008 1 YDR180W SCC2 SGDID:S000002588,Putative protein kinase and subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for the loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during DSB repair via histone H2AX, Chr IV from 821292-825773, Verified ORF YPR185W 27.84 1.00 14 703.0135 1 YPR185W ATG13 SGDID:S000006389,Phosphorylated protein that interacts with Vac8p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway and autophagy, Chr XVI from 907214-909430, Verified ORF YJR091C 26.46 0.90 2 95.1015 1 YJR091C JSN1 SGDID:S000003851,Member of the Puf family of RNA-binding proteins, interacts with mRNAs encoding membrane-associated proteins; overexpression suppresses a tub2-150 mutation and causes increased sensitivity to benomyl in wild-type cells, Chr X from 598251-594976, reverse complement, Verified ORF YLR359W 25.79 1.00 71 3848.681 1 YLR359W ADE13 SGDID:S000004351,Adenylosuccinate lyase, catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway, Chr XII from 844281-845729, Verified ORF YPL217C 53.239 1.00 10 262.588 1 YPL217C BMS1 SGDID:S000006138,Essential conserved nucleolar GTP-binding protein required for synthesis of 40S ribosomal subunits and for processing of the 35S pre-rRNA at sites A0, A1, and A2; interacts with Rcl1p, has similarity to Tsr1p, Chr XVI from 143170-139619, reverse complement, Verified ORF YLR244C 12.3 1.00 18 2045.843 1 YLR244C MAP1 SGDID:S000004234,Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p, Chr XII from 626333-625170, reverse complement, Verified ORF YMR236W 7.97 0.99 3 520.9583 1 YMR236W TAF9 SGDID:S000004849,Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H3, Chr XIII from 742970-743443, Verified ORF YOR234C 6.01 1.00 71 16515.3883 1 YOR234C RPL33B SGDID:S000005760,Ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Ap and has similarity to rat L35a; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable, Chr XV from 779406-779388,778860-778556, reverse complement, Verified ORF YIL169C 13.417 0.93 2 193.8038 1 YIL169C YIL169C SGDID:S000001431,Putative protein of unknown function; serine\threonine rich and highly similar to YOL155C, a putative glucan alpha-1,4-glucosidase; transcript is induced in both high and low pH environments; YIL169C is a non-essential gene, Chr IX from 26106-23119, reverse complement, Uncharacterized ORF YDR465C 18.4 0.92 1 69.8996 1 YDR465C RMT2 SGDID:S000002873,Arginine methyltransferase; ribosomal protein L12 is a substrate, Chr IV from 1394566-1393328, reverse complement, Verified ORF YCL030C 34.027 1.00 116 4765.8376 1 YCL030C HIS4 SGDID:S000000535,Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase, phosphoribosyl-AMP cyclohydrolase, and histidinol dehydrogenase activities; catalyzes the second, third, ninth and tenth steps in histidine biosynthesis, Chr III from 68333-65934, reverse complement, Verified ORF YDR044W 13.36 0.99 6 621.5626 1 YDR044W HEM13 SGDID:S000002451,Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p), Chr IV from 546640-547626, Verified ORF YIR001C 9.64 0.81 3 352.3985 1 YIR001C SGN1 SGDID:S000001440,Cytoplasmic RNA-binding protein, contains an RNA recognition motif (RRM); may have a role in mRNA translation, as suggested by genetic interactions with genes encoding proteins involved in translational initiation, Chr IX from 356892-356140, reverse complement, Verified ORF YLR118C 7.07 0.99 3 587.2755 1 YLR118C YLR118C SGDID:S000004108,Acyl-protein thioesterase responsible for depalmitoylation of Gpa1p; the mutant has no gross defects in signaling through the mating pathway; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus, Chr XII from 385409-384726, reverse complement, Verified ORF YDR321W 11.92 1.00 19 2228.3441 1 YDR321W ASP1 SGDID:S000002729,Cytosolic L-asparaginase, involved in asparagine catabolism, Chr IV from 1108699-1109844, Verified ORF YKR057W 6.688 1.00 86 17976.5811 1 YKR057W RPS21A SGDID:S000001765,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Bp and has similarity to rat S21 ribosomal protein, Chr XI from 551299-551322,551645-551884, Verified ORF YAR073W 14.79 1.00 2 189.0456 1 YAR073W IMD1 SGDID:S000000095,Nonfunctional protein with homology to IMP dehydrogenase; probable pseudogene, located close to the telomere; is not expressed at detectable levels; YAR073W and YAR075W comprise a continuous reading frame in some strains of S. cerevisiae, Chr I from 227733-228944, Dubious ORF YDR387C 11.009 0.83 1 105.3986 1 YDR387C YDR387C SGDID:S000002795,Hypothetical protein, Chr IV from 1249813-1248146, reverse complement, Uncharacterized ORF YOL130W 27.08 1.00 12 619.4945 1 YOL130W ALR1 SGDID:S000005490,Plasma membrane Mg(2+) transporter, expression and turnover are regulated by Mg(2+) concentration; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions, Chr XV from 74400-76979, Verified ORF YFL037W 13.35 1.00 119 12461.5082 1 YFL037W TUB2 SGDID:S000001857,Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymerizes to form microtubules, Chr VI from 56335-57708, Verified ORF YER178W 19.24 1.00 74 5376.8951 1 YER178W PDA1 SGDID:S000000980,E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the direct oxidative decarboxylation of pyruvate to acetyl-CoA, regulated by glucose, Chr V from 546812-548074, Verified ORF YDL031W 49.24 1.00 8 227.1312 1 YDL031W DBP10 SGDID:S000002189,Putative ATP-dependent RNA helicase of the DEAD-box protein family, constituent of 66S pre-ribosomal particles; essential protein involved in ribosome biogenesis, Chr IV from 394214-397201, Verified ORF YER105C 57.927 1.00 5 120.6684 1 YER105C NUP157 SGDID:S000000907,Abundant subunit of the nuclear pore complex (NPC), present on both sides of the NPC, has similarity to Nup170p, Chr V from 372009-367834, reverse complement, Verified ORF YIL055C 20.15 0.71 1 49.2592 1 YIL055C YIL055C SGDID:S000001317,Hypothetical protein, Chr IX from 253923-252040, reverse complement, Uncharacterized ORF YLR246W 8.69 0.67 4 431.1416 1 YLR246W ERF2 SGDID:S000004236,Subunit of a palmitoyltransferase, composed of Erf2p and Shr5p, that adds a palmitoyl lipid moiety to Ras2p through a thioester linkage; mutants partially mislocalize Ras2p to the vacuole, Chr XII from 627120-628199, Verified ORF YNR001C 23.06 1.00 36 2182.4691 1 YNR001C CIT1 SGDID:S000005284,Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate; the rate-limiting enzyme of the TCA cycle; nuclear encoded mitochondrial protein, Chr XIV from 631063-629624, reverse complement, Verified ORF YJL140W 10.87 0.94 1 120.8935 1 YJL140W RPB4 SGDID:S000003676,RNA polymerase II subunit B32; forms two subunit dissociable complex with Rpb7p; dispensable under some environmental conditions; involved in export of mRNA to cytoplasm under stress conditions; involved in telomere maintenance, Chr X from 150880-151545, Verified ORF YKL157W 51.066 1.00 52 1423.562 1 YKL157W APE2 SGDID:S000001640,Zinc-dependent metallopeptidase yscII, may have a role in obtaining leucine from dipeptide substrates; sequence coordinates have changed since RT-PCR analysis showed that the adjacent ORF YKL158W comprises the 5' exon of APE2\YKL157W, Chr XI from 154996-155276,155660-158186, Verified ORF YIL116W 15.13 0.99 2 182.9494 1 YIL116W HIS5 SGDID:S000001378,Histidinol-phosphate aminotransferase, catalyzes the seventh step in histidine biosynthesis; responsive to general control of amino acid biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts, Chr IX from 142925-144082, Verified ORF YGR100W 45.1 0.88 3 81.8337 1 YGR100W MDR1 SGDID:S000003332,Cytoplasmic GTPase-activating protein for Ypt\Rab transport GTPases Ypt6p, Ypt31p and Sec4p; involved in recycling of internalized proteins and regulation of Golgi secretory function, Chr VII from 690249-693101, Verified ORF YER088C 24.25 0.91 6 314.7645 1 YER088C DOT6 SGDID:S000000890,Protein of unknown function, involved in telomeric gene silencing and filamentation, Chr V from 335184-333172, reverse complement, Verified ORF YER172C 87.956 0.82 4 52.133 1 YER172C BRR2 SGDID:S000000974,RNA-dependent ATPase RNA helicase involved in the facilitation and disruption of snRNA interactions, required for disruption of U4\U6 base-pairing in native snRNPs to activate the spliceosome for catalysis, Chr V from 536016-529525, reverse complement, Verified ORF YDL112W 65.284 1.00 9 192.7261 1 YDL112W TRM3 SGDID:S000002270,2'-O-ribose methyltransferase, catalyzes the ribose methylation of the guanosine nucleotide at position 18 of tRNAs, Chr IV from 258915-263225, Verified ORF YER014W 31.93 0.96 1 42.0317 1 YER014W HEM14 SGDID:S000000816,Protoporphyrinogen oxidase, a mitochondrial enzyme that catalyzes the seventh step in the heme biosynthetic pathway, converting protoporphyrinogen IX to protoporphyrin IX, Chr V from 182599-184218, Verified ORF YBL080C 23.45 0.88 10 524.6198 1 YBL080C PET112 SGDID:S000000176,Protein required for mitochondrial translation; mutation is functionally complemented by a Bacillus subtilis ortholog, Chr II from 74692-73067, reverse complement, Verified ORF YNL034W 18.568 0.68 12 614.3699 1 YNL034W YNL034W SGDID:S000004979,Hypothetical protein, Chr XIV from 570478-572316, Uncharacterized ORF YER158C 21.49 0.96 19 1186.5699 1 YER158C YER158C SGDID:S000000960,Protein of unknown function, has similarity to Afr1p; potentially phosphorylated by Cdc28p, Chr V from 490573-488852, reverse complement, Uncharacterized ORF YNL189W 12.52 1.00 8 893.286 1 YNL189W SRP1 SGDID:S000005133,Karyopherin alpha homolog, forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; may also play a role in regulation of protein degradation, Chr XIV from 284261-285889, Verified ORF YER049W 30.867 1.00 13 588.781 1 YER049W YER049W SGDID:S000000851,Hypothetical protein, Chr V from 251727-253661, Uncharacterized ORF YKL109W 17.59 0.89 2 141.4682 1 YKL109W HAP4 SGDID:S000001592,Subunit of the heme-activated, glucose-repressed Hap2p\3p\4p\5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; provides the principal activation function of the complex, Chr XI from 231871-233535, Verified ORF YFR001W 8.33 1.00 5 839.1312 1 YFR001W LOC1 SGDID:S000001897,Nuclear protein involved in asymmetric localization of ASH1 mRNA; binds double-stranded RNA in vitro; constituent of 66S pre-ribosomal particles, Chr VI from 149105-149719, Verified ORF YGL091C 10.29 0.92 1 124.9906 1 YGL091C NBP35 SGDID:S000003059,Essential nuclear protein, evolutionarily conserved putative ATPase; exhibits genetic interaction with CDC2 encoding the catalytic subunit of DNA polymerase delta, Chr VII from 343045-342059, reverse complement, Verified ORF YER042W 9.562 0.98 4 573.1156 1 YER042W MXR1 SGDID:S000000844,Peptide methionine sulfoxide reductase, reverses the oxidation of methionine residues; involved in oxidative damage repair, providing resistance to oxidative stress and regulation of lifespan, Chr V from 234936-235490, Verified ORF YJL100W 22.44 0.98 9 549.4784 1 YJL100W LSB6 SGDID:S000003636,Phosphatidylinositol 4-kinase that binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization, Chr X from 237181-239004, Verified ORF YHR047C 44.48 1.00 36 1131.4689 1 YHR047C AAP1 SGDID:S000001089,Arginine\alanine aminopeptidase, overproduction stimulates glycogen accumulation, Chr VIII from 201303-198733, reverse complement, Verified ORF YIL075C 45.695 1.00 12 367.1279 1 YIL075C RPN2 SGDID:S000001337,Subunit of the 26S proteasome, substrate of the N-acetyltransferase Nat1p, Chr IX from 220697-217860, reverse complement, Verified ORF YJL192C 8.21 0.82 1 139.6289 1 YJL192C SOP4 SGDID:S000003728,ER-membrane protein; suppressor of pma1-7, deletion of SOP4 slows down the export of wild-type Pma1p and Pma1-7 from the ER, Chr X from 73413-72709, reverse complement, Verified ORF YJL171C 9.55 0.99 5 724.614 1 YJL171C YJL171C SGDID:S000003707,GPI-anchored cell wall protein of unknown function; induced in response to cell wall damaging agents and by mutations in genes involved in cell wall biogenesis; sequence similarity to YBR162C\TOS1, a covalently bound cell wall protein, Chr X from 100888-99698, reverse complement, Verified ORF YLR369W 35.1 0.89 14 496.2675 1 YLR369W SSQ1 SGDID:S000004361,Mitochondrial hsp70-type molecular chaperone, required for assembly of iron\sulfur clusters into proteins at a step after cluster synthesis, and for maturation of Yfh1p, which is a homolog of human frataxin implicated in Friedreich's ataxia, Chr XII from 859551-861524, Verified ORF YGL201C 40.178 1.00 11 382.7447 1 YGL201C MCM6 SGDID:S000003169,Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex, Chr VII from 120911-117858, reverse complement, Verified ORF YBR039W 16.015 1.00 20 1745.8541 1 YBR039W ATP3 SGDID:S000000243,Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis, Chr II from 315575-316510, Verified ORF YAL035W 35.569 1.00 41 1611.451 1 YAL035W FUN12 SGDID:S000000033,GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; homolog of bacterial IF2, Chr I from 76428-79436, Verified ORF YBR259W 32.25 0.69 4 119.6421 1 YBR259W YBR259W SGDID:S000000463,Putative protein of unknown function; YBR259W is not an essential gene, Chr II from 730382-732448, Uncharacterized ORF YNL015W 5.45 0.99 1 253.9473 1 YNL015W PBI2 SGDID:S000004960,Cytosolic inhibitor of vacuolar proteinase B, required for efficient vacuole inheritance; with thioredoxin forms protein complex LMA1, which assists in priming SNARE molecules and promotes vacuole fusion, Chr XIV from 605385-605612, Verified ORF YGL181W 14.28 0.97 1 94.9616 1 YGL181W GTS1 SGDID:S000003149,Protein containing a zinc-finger in the N-terminus and a long Gln-rich region in the C-terminus; regulates ultradian rhythm, cell size, cell cycle, lifespan, sporulation, heat tolerance, and multidrug transport, Chr VII from 157912-159102, Verified ORF YPR036W 22.839 1.00 45 2754.4845 1 YPR036W VMA13 SGDID:S000006240,Subunit H of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; serves as an activator or a structural stabilizer of the V-ATPase, Chr XVI from 643833-645269, Verified ORF YLR096W 48.92 0.73 3 62.5838 1 YLR096W KIN2 SGDID:S000004086,Serine\threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin1p, Chr XII from 332591-336034, Verified ORF YEL060C 23.067 0.95 18 1036.3582 1 YEL060C PRB1 SGDID:S000000786,Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation, Chr V from 41953-40046, reverse complement, Verified ORF YDL226C 18.47 1.00 22 1665.1781 1 YDL226C GCS1 SGDID:S000002385,ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Glo3p, Chr IV from 52174-51116, reverse complement, Verified ORF YOL051W 36.59 1.00 9 343.8626 1 YOL051W GAL11 SGDID:S000005411,Component of the Mediator complex; interacts with RNA polymerase II and the general transcription factors to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors, Chr XV from 234939-238184, Verified ORF YDR394W 18.14 1.00 7 539.4679 1 YDR394W RPT3 SGDID:S000002802,One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; substrate of N-acetyltransferase B, Chr IV from 1261673-1262959, Verified ORF YDR188W 22.55 1.00 29 1797.862 1 YDR188W CCT6 SGDID:S000002596,Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, essential protein that is required for the assembly of actin and tubulins in vivo; contains an ATP-binding motif, Chr IV from 836418-838058, Verified ORF YMR243C 5.83 0.99 12 2848.7399 1 YMR243C ZRC1 SGDID:S000004856,Vacuolar membrane zinc transporter, transports zinc from the cytosol into the vacuole for storage; also has a role in resistance to zinc shock resulting from a sudden influx of zinc into the cytoplasm, Chr XIII from 756165-754837, reverse complement, Verified ORF YDR324C 31.35 0.98 4 174.8048 1 YDR324C UTP4 SGDID:S000002732,Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA, Chr IV from 1116760-1114430, reverse complement, Verified ORF YNR034W-A 8.08 0.99 1 171.2887 1 YNR034W-A YNR034W-A SGDID:S000007525,Hypothetical protein, Chr XIV from 692563-692859, Uncharacterized ORF YMR079W 18.31 1.00 78 5955.4032 1 YMR079W SEC14 SGDID:S000004684,Phosphatidylinositol\phosphatidylcholine transfer protein involved in coordinate regulation of PtdIns and PtdCho metabolism, products of which are regulators in Golgi to plasma membrane transport; functionally homologous to mammalian PITPs, Chr XIII from 424988-424996,425153-426058, Verified ORF YKR081C 11.018 1.00 19 2410.7698 1 YKR081C RPF2 SGDID:S000001789,Essential protein involved in the processing of pre-rRNA and the assembly of the 60S ribosomal subunit; interacts with ribosomal protein L11; localizes predominantly to the nucleolus; constituent of 66S pre-ribosomal particles, Chr XI from 592182-591148, reverse complement, Verified ORF YEL023C 28.05 0.97 8 386.753 1 YEL023C YEL023C SGDID:S000000749,Hypothetical protein, Chr V from 110552-108504, reverse complement, Uncharacterized ORF YNL045W 29.9 1.00 32 1496.1795 1 YNL045W YNL045W SGDID:S000004990,Leucyl aminopeptidase (leukotriene A4 hydrolase) with epoxide hydrolase activity, metalloenzyme containing one zinc atom; role in vivo is not defined, Chr XIV from 542964-544979, Verified ORF YMR264W 9.9 1.00 12 1694.5366 1 YMR264W CUE1 SGDID:S000004877,Endoplasmic reticulum membrane protein that recruits the ubiquitin-conjugating enzyme Ubc7p to the ER where it functions in protein degradation; contains a CUE domain that binds ubiquitin to facilitate intramolecular monoubiquitination, Chr XIII from 795804-796415, Verified ORF YLR401C 30.648 1.00 9 410.5303 1 YLR401C DUS3 SGDID:S000004393,Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus4p; contains a consensus oleate response element (ORE) in its promoter region, Chr XII from 924448-922442, reverse complement, Uncharacterized ORF YLR200W 6.36 1.00 9 1978.2915 1 YLR200W YKE2 SGDID:S000004190,Subunit of the heterohexameric Gim\prefoldin protein complex involved in the folding of alpha-tubulin, beta-tubulin, and actin, Chr XII from 549014-549358, Verified ORF YBR080C 39.82 1.00 11 386.1858 1 YBR080C SEC18 SGDID:S000000284,ATPase required for the release of Sec17p during the 'priming' step in homotypic vacuole fusion and for ER to Golgi transport; homolog of the mammalian NSF, Chr II from 400884-398608, reverse complement, Verified ORF YPR141C 32.53 0.97 5 208.4311 1 YPR141C KAR3 SGDID:S000006345,Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating; potential Cdc28p substrate, Chr XVI from 817919-815730, reverse complement, Verified ORF YOR243C 34.899 1.00 16 640.9319 1 YOR243C PUS7 SGDID:S000005769,Pseudouridine synthase, catalyzes pseudouridylation at position 35 in U2 snRNA, position 13 in cytoplasmic tRNAs, and position 35 in pre-tRNA(Tyr); Asp(256) mutation abolishes activity; conserved in archaea, some bacteria, and vertebrates, Chr XV from 792242-790212, reverse complement, Verified ORF YIL133C 14.3 1.00 57 5572.4185 1 YIL133C RPL16A SGDID:S000001395,N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Bp, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p, Chr IX from 99416-99386,99095-98527, reverse complement, Verified ORF YGR286C 13.7 0.73 2 148.9831 1 YGR286C BIO2 SGDID:S000003518,Biotin synthase, catalyzes the conversion of dethiobiotin to biotin, which is the last step of the biotin biosynthesis pathway; complements E. coli bioB mutant, Chr VII from 1064946-1063819, reverse complement, Verified ORF YJR136C 16.41 1.00 20 1703.8302 1 YJR136C YJR136C SGDID:S000003897,Putative protein of unknown function; may interact with mitochondrial ribosomal protein Rsm23p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, Chr X from 678622-677357, reverse complement, Uncharacterized ORF YAL005C 25.765 1.00 783 42485.0885 1 YAL005C SSA1 SGDID:S000000004,ATPase involved in protein folding and nuclear localization signal (NLS)-directed nuclear transport; member of heat shock protein 70 (HSP70) family; forms a chaperone complex with Ydj1p; localized to the nucleus, cytoplasm, and cell wall, Chr I from 141433-139505, reverse complement, Verified ORF YER155C 89.8030000000001 1.00 29 451.4525 1 YER155C BEM2 SGDID:S000000957,Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton organization and cellular morphogenesis; required for bud emergence, Chr V from 482843-476340, reverse complement, Verified ORF YNL282W 5.13 0.96 1 261.6126 1 YNL282W POP3 SGDID:S000005226,Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends, Chr XIV from 107687-108274, Verified ORF YNL207W 17.129 1.00 4 326.4621 1 YNL207W RIO2 SGDID:S000005151,Essential serine kinase involved in the processing of the 20S pre-rRNA into mature 18S rRNA; has similarity to Rio1p, Chr XIV from 255354-256631, Verified ORF YER110C 44.2 1.00 362 11449.6237 1 YER110C KAP123 SGDID:S000000912,Karyopherin beta, mediates nuclear import of ribosomal proteins prior to assembly into ribosomes and import of histones H3 and H4; localizes to the nuclear pore, nucleus, and cytoplasm; exhibits genetic interactions with RAI1, Chr V from 382099-378758, reverse complement, Verified ORF YAL030W 4.12 1.00 6 2035.9117 1 YAL030W SNC1 SGDID:S000000028,Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; proposed to be involved in endocytosis; member of the synaptobrevin\VAMP family of R-type v-SNARE proteins, Chr I from 87287-87388,87502-87753, Verified ORF YPL131W 12.09 1.00 325 37580.4496 1 YPL131W RPL5 SGDID:S000006052,Protein component of the large (60S) ribosomal subunit with similarity to E. coli L18 and rat L5 ribosomal proteins; binds 5S rRNA and is required for 60S subunit assembly, Chr XVI from 303120-304013, Verified ORF YER005W 23.51 1.00 16 951.4199 1 YER005W YND1 SGDID:S000000807,Apyrase with wide substrate specificity, involved in preventing the inhibition of glycosylation by hydrolyzing nucleoside tri- and diphosphates which are inhibitors of glycotransferases; partially redundant with Gda1p, Chr V from 160549-162441, Verified ORF YGL137W 35.108 1.00 66 2628.1052 1 YGL137W SEC27 SGDID:S000003105,Essential beta'-coat protein of the COPI coatomer, involved in ER-to-Golgi and Golgi-to-ER transport; contains WD40 domains that mediate cargo selective interactions; 45% sequence identity to mammalian beta'-COP, Chr VII from 249874-249891,250092-252743, Verified ORF YPL040C 46.097 0.99 11 330.2631 1 YPL040C ISM1 SGDID:S000005961,Mitochondrial isoleucyl-tRNA synthetase, null mutant is deficient in respiratory growth, Chr XVI from 478998-475990, reverse complement, Verified ORF YNL212W 43.979 1.00 2 63.5754 1 YNL212W VID27 SGDID:S000005156,Cytoplasmic protein of unknown function; possibly involved in vacuolar protein degradation; not essential for proteasome-dependent degradation of fructose-1,6-bisphosphatase (FBPase); null mutants exhibit normal growth, Chr XIV from 247462-249810, Verified ORF YER156C 19.38 1.00 13 937.766 1 YER156C YER156C SGDID:S000000958,Hypothetical protein, Chr V from 484336-483320, reverse complement, Uncharacterized ORF YHR005C-A 5.47 0.99 1 253.0187 1 YHR005C-A MRS11 SGDID:S000003530,Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that mediates insertion of hydrophobic proteins at the inner membrane, has homology to Mrs5p, which is also involved in this process, Chr VIII from 115896-115615, reverse complement, Verified ORF YMR120C 30.439 1.00 125 5740.9603 1 YMR120C ADE17 SGDID:S000004727,Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade16p; ade16 ade17 mutants require adenine and histidine, Chr XIII from 509279-507501, reverse complement, Verified ORF YLR454W 122.034 1.00 39 446.7748 1 YLR454W YLR454W SGDID:S000004446,The authentic, non-tagged protein was localized to the mitochondria, Chr XII from 1043996-1051882, Uncharacterized ORF YLR224W 11.81 0.77 1 91.1477 1 YLR224W YLR224W SGDID:S000004214,Hypothetical protein, Chr XII from 586466-587575, Uncharacterized ORF YPL016W 33.23 0.99 7 291.5464 1 YPL016W SWI1 SGDID:S000005937,Subunit of the SWI\SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2, Chr XVI from 521011-524955, Verified ORF YNR023W 25.87 0.97 22 1153.1953 1 YNR023W SNF12 SGDID:S000005306,73 kDa subunit of the SWI\SNF chromatin remodeling complex involved in transcriptional regulation; homolog of Rsc6p subunit of the RSC chromatin remodeling complex; deletion mutants are temperature-sensitive, Chr XIV from 670420-672120, Verified ORF YKL064W 25.5 0.94 3 154.6015 1 YKL064W MNR2 SGDID:S000001547,Putative magnesium transporter; has similarity to Alr1p and Alr2p, which mediate influx of Mg2+ and other divalent cations, Chr XI from 317408-320317, Verified ORF YER122C 21.645 0.99 7 447.5901 1 YER122C GLO3 SGDID:S000000924,ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Gcs1p, Chr V from 404348-402867, reverse complement, Verified ORF YDR322C-A 5.55 1.00 3 755.6717 1 YDR322C-A TIM11 SGDID:S000007255,Subunit e of mitochondrial F1F0-ATPase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; essential for the dimeric state of ATP synthase, Chr IV from 1112290-1112000, reverse complement, Verified ORF YGR150C 45.856 0.85 21 544.1854 1 YGR150C YGR150C SGDID:S000003382,Putative protein of unknown function; deletion mutant has growth defects on both non-fermentable carbon sources and rich medium; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; contains PPR motifs, Chr VII from 793058-790464, reverse complement, Uncharacterized ORF YGR074W 3.89 0.99 2 711.5747 1 YGR074W SMD1 SGDID:S000003306,Core Sm protein Sm D1; part of heteroheptameric complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D1, Chr VII from 635716-636156, Verified ORF YLR390W-A 5.52 0.98 2 496.3887 1 YLR390W-A CCW14 SGDID:S000006429,Covalently linked cell wall glycoprotein, present in the inner layer of the cell wall, Chr XII from 903724-904440, Verified ORF YDR089W 33.33 0.73 3 91.8573 1 YDR089W YDR089W SGDID:S000002496,Hypothetical protein, Chr IV from 622109-624718, Uncharacterized ORF YGL180W 39.33 0.90 8 255.9254 1 YGL180W ATG1 SGDID:S000003148,Protein serine\threonine kinase, required for autophagy and for the cytoplasm-to-vacuole targeting (Cvt) pathway, Chr VII from 160071-162764, Verified ORF YDR017C 40.6 0.97 18 601.2057 1 YDR017C KCS1 SGDID:S000002424,Inositol hexaphosphate kinase, phosphorylates inositol hexakisphosphate (InsP6) to diphosphoinositol polyphosphates, required for proper vacuole morphology and involved in salt stress response, contains two leucine heptad repeats, Chr IV from 482264-479112, reverse complement, Verified ORF YMR176W 68.859 0.95 5 96.4356 1 YMR176W ECM5 SGDID:S000004788,Non-essential protein of unknown function, contains ATP\GTP-binding site motif A; null mutant exhibits cellular volume up to four times greater than wild-type, also large drooping buds with elongated necks, Chr XIII from 611739-615974, Verified ORF YML070W 28.74 1.00 34 1653.8536 1 YML070W DAK1 SGDID:S000004535,Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation, Chr XIII from 133475-135229, Verified ORF YPL043W 34.77 1.00 8 321.6549 1 YPL043W NOP4 SGDID:S000005964,Nucleolar protein, essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; contains four RNA recognition motifs (RRMs), Chr XVI from 469936-471993, Verified ORF YHR011W 22.62 0.68 3 126.0789 1 YHR011W DIA4 SGDID:S000001053,Probable mitochondrial seryl-tRNA synthetase, mutant displays increased invasive and pseudohyphal growth, Chr VIII from 127774-129114, Verified ORF YOR048C 44.558 1.00 16 501.9947 1 YOR048C RAT1 SGDID:S000005574,Nuclear 5' to 3' single-stranded RNA exonuclease, involved in RNA metabolism, including rRNA and snRNA processing as well as mRNA transcription termination, Chr XV from 421651-418631, reverse complement, Verified ORF YDL235C 9.04 0.98 1 151.5523 1 YDL235C YPD1 SGDID:S000002394,Phosphorelay intermediate protein, phosphorylated by the plasma membrane sensor Sln1p in response to osmotic stress and then in turn phosphorylates the response regulators Ssk1p in the cytosol and Skn7p in the nucleus, Chr IV from 33918-33415, reverse complement, Verified ORF YBR275C 85.57 1.00 17 277.736 1 YBR275C RIF1 SGDID:S000000479,Protein that binds to the Rap1p C-terminus and acts synergistically with Rif2p to help control telomere length and establish telomeric silencing; deletion results in telomere elongation, Chr II from 757101-751351, reverse complement, Verified ORF YOR175C 21.17 0.87 1 57.4517 1 YOR175C YOR175C SGDID:S000005701,Member of the MBOAT family of putative membrane-bound O-acyltransferases, Chr XV from 661675-659816, reverse complement, Uncharacterized ORF YLR278C 39.69 0.65 1 22.8948 1 YLR278C YLR278C SGDID:S000004268,Protein of unknown function, localizes to the nucleus; potential Cdc28p substrate, Chr XII from 704026-700001, reverse complement, Uncharacterized ORF YHR025W 10.5 1.00 58 7722.2455 1 YHR025W THR1 SGDID:S000001067,Homoserine kinase, conserved protein required for threonine biosynthesis; expression is regulated by the GCN4-mediated general amino acid control pathway, Chr VIII from 159431-160504, Verified ORF YNL118C 42.73 1.00 5 163.5844 1 YNL118C DCP2 SGDID:S000005062,Catalytic subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; member of the Nudix hydrolase family, Chr XIV from 405566-402654, reverse complement, Verified ORF YNL037C 15.969 1.00 40 3501.7664 1 YNL037C IDH1 SGDID:S000004982,Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle, Chr XIV from 559003-557921, reverse complement, Verified ORF YDR099W 12.79 0.99 1 108.2105 1 YDR099W BMH2 SGDID:S000002506,14-3-3 protein, minor isoform; binds proteins and DNA, involved in regulation of many processes including exocytosis and vesicle transport, Ras\MAPK signaling during pseudohyphal development, rapamycin-sensitive signaling, and others, Chr IV from 653604-654425, Verified ORF YNL278W 40.79 0.99 5 169.6509 1 YNL278W CAF120 SGDID:S000005222,Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation, Chr XIV from 113271-116453, Verified ORF YNR050C 22.5 1.00 30 1863.9903 1 YNR050C LYS9 SGDID:S000005333,Saccharopine dehydrogenase (NADP+, L-glutamate-forming); catalyzes the formation of saccharopine from alpha-aminoadipate 6-semialdehyde, which is the seventh step in lysine biosynthesis pathway, Chr XIV from 715390-714050, reverse complement, Verified ORF YJL109C 78.71 1.00 13 230.897 1 YJL109C UTP10 SGDID:S000003645,Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA, Chr X from 217227-211918, reverse complement, Verified ORF YGL179C 17.1 0.80 6 392.419 1 YGL179C TOS3 SGDID:S000003147,Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome, Chr VII from 165097-163415, reverse complement, Verified ORF YMR216C 31.18 0.85 5 190.5538 1 YMR216C SKY1 SGDID:S000004829,SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1, Chr XIII from 701038-698810, reverse complement, Verified ORF YDR211W 27.12 1.00 9 463.9356 1 YDR211W GCD6 SGDID:S000002619,Catalytic epsilon subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression, Chr IV from 884724-886862, Verified ORF YPL169C 22.59 0.96 1 59.41 1 YPL169C MEX67 SGDID:S000006090,Poly(A)RNA binding protein involved in nuclear mRNA export, component of the nuclear pore; ortholog of human TAP, Chr XVI from 230837-229038, reverse complement, Verified ORF YLR196W 24.43 1.00 15 858.3663 1 YLR196W PWP1 SGDID:S000004186,Protein with WD-40 repeats involved in rRNA processing; associates with trans-acting ribosome biogenesis factors; similar to beta-transducin superfamily, Chr XII from 543970-545700, Verified ORF YOL038W 9.42 1.00 17 2522.9168 1 YOL038W PRE6 SGDID:S000005398,20S proteasome alpha-type subunit, Chr XV from 255336-256100, Verified ORF YKL134C 36.07 1.00 7 271.3043 1 YKL134C OCT1 SGDID:S000001617,Mitochondrial intermediate peptidase, cleaves N-terminal residues of a subset of proteins upon import, after their cleavage by mitochondrial processing peptidase (Mas1p-Mas2p); may contribute to mitochondrial iron homeostasis, Chr XI from 191441-189129, reverse complement, Verified ORF YKR006C 15.12 0.98 1 90.6106 1 YKR006C MRPL13 SGDID:S000001714,Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation, Chr XI from 450860-450066, reverse complement, Verified ORF YPL207W 29.636 0.99 2 93.4007 1 YPL207W YPL207W SGDID:S000006128,Hypothetical protein, Chr XVI from 159908-162340, Uncharacterized ORF YDR190C 24.8 1.00 7 394.5947 1 YDR190C RVB1 SGDID:S000002598,Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; member of the RUVB-like protein family, Chr IV from 841992-840601, reverse complement, Verified ORF YBL039C 25.336 1.00 53 2924.4401 1 YBL039C URA7 SGDID:S000000135,Major CTP synthase isozyme (see also URA8), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis, Chr II from 145731-143992, reverse complement, Verified ORF YBR079C 48.12 1.00 116 3370.0572 1 YBR079C RPG1 SGDID:S000000283,Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes, Chr II from 398271-395377, reverse complement, Verified ORF YGL203C 27.843 0.96 11 530.2159 1 YGL203C KEX1 SGDID:S000003171,Protease involved in the processing of killer toxin and alpha factor precursor; cleaves Lys and Arg residues from the C-terminus of peptides and proteins, Chr VII from 114668-112479, reverse complement, Verified ORF YPL271W 4.38 0.73 1 232.9987 1 YPL271W ATP15 SGDID:S000006192,Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis, Chr XVI from 30079-30267, Verified ORF YHR077C 53.279 0.80 3 62.9738 1 YHR077C NMD2 SGDID:S000001119,Protein involved in the nonsense-mediated mRNA decay (NMD) pathway; interacts with Nam7p and Upf3p; involved in telomere maintenance, Chr VIII from 255758-255753,255639-252376, reverse complement, Verified ORF YLR356W 3.04 0.95 1 436.8727 1 YLR356W YLR356W SGDID:S000004348,Hypothetical protein, Chr XII from 840320-840913, Uncharacterized ORF YMR307W 14.86 1.00 43 4045.3356 1 YMR307W GAS1 SGDID:S000004924,Beta-1.3-glucanosyltransferase, required for cell wall assembly; localizes to the cell surface via a glycosylphosphatidylinositol (GPI) anchor, Chr XIII from 887002-888681, Verified ORF YPL057C 16.58 0.65 2 109.6134 1 YPL057C SUR1 SGDID:S000005978,Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Csh1p, Chr XVI from 453054-451906, reverse complement, Verified ORF YBR073W 41.48 0.78 5 131.4409 1 YBR073W RDH54 SGDID:S000000277,DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during mitosis and meiosis; proposed to be involved in crossover interference, Chr II from 383209-385983, Verified ORF YLR432W 19.36 1.00 63 4549.2531 1 YLR432W IMD3 SGDID:S000004424,Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed, Chr XII from 1002554-1004125, Verified ORF YNL082W 41.497 0.70 4 94.3292 1 YNL082W PMS1 SGDID:S000005026,ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer with Mlh1p, binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL, Chr XIV from 473392-476013, Verified ORF YDL237W 14.27 1.00 11 1077.6398 1 YDL237W YDL237W SGDID:S000002396,Hypothetical protein, Chr IV from 30657-31829, Uncharacterized ORF YDL195W 38.81 1.00 53 1909.1371 1 YDL195W SEC31 SGDID:S000002354,Essential phosphoprotein component (p150) of the COPII coat of secretory pathway vesicles, in complex with Sec13p; required for ER-derived transport vesicle formation, Chr IV from 107209-111030, Verified ORF YNL161W 17.648 0.68 1 53.8664 1 YNL161W CBK1 SGDID:S000005105,Serine\threonine protein kinase that regulates cell morphogenesis pathways; involved in cell wall biosynthesis, apical growth, proper mating projection morphology, bipolar bud site selection in diploid cells, and cell separation, Chr XIV from 332599-334869, Verified ORF YPR095C 49.517 0.73 2 41.2195 1 YPR095C SYT1 SGDID:S000006299,Guanine nucleotide exchange factor (GEF) for Arf proteins; involved in vesicular transport; suppressor of ypt3 mutations; member of the Sec7-domain family, Chr XVI from 724715-721035, reverse complement, Verified ORF YLL048C 67.205 1.00 18 374.4344 1 YLL048C YBT1 SGDID:S000003971,Transporter of the ATP-binding cassette (ABC) family involved in bile acid transport; similar to mammalian bile transporters, Chr XII from 46264-41279, reverse complement, Verified ORF YDR334W 60.31 1.00 17 394.0619 1 YDR334W SWR1 SGDID:S000002742,Swi2\Snf2-related ATPase, component of the SWR1 complex; required for the incorporation of Htz1p into chromatin, Chr IV from 1135927-1140471, Verified ORF YDL052C 13.508 1.00 8 827.9494 1 YDL052C SLC1 SGDID:S000002210,1-acyl-sn-gylcerol-3-phosphate acyltransferase, catalyzes the acylation of lysophosphatidic acid to form phosphatidic acid, a key intermediate in lipid metabolism; located in lipid particles and endoplasmic reticulum, Chr IV from 363583-362672, reverse complement, Verified ORF YGL148W 15.999 1.00 43 3757.3402 1 YGL148W ARO2 SGDID:S000003116,Bifunctional chorismate synthase and flavin reductase, catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids, Chr VII from 226404-227534, Verified ORF YDR310C 50.798 0.99 2 54.4908 1 YDR310C SUM1 SGDID:S000002718,Transcriptional repressor required for mitotic repression of middle sporulation-specific genes; involved in telomere maintenance, regulated by the pachytene checkpoint, Chr IV from 1084312-1081124, reverse complement, Verified ORF YBR084C-A 6.95 1.00 216 43448.4071 2 YBR084C-A,YBL027W RPL19A SGDID:S000002156,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl19Bp and has similarity to rat L19 ribosomal protein; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal, Chr II from 415255-415254,414747-414180, reverse complement, Verified ORF YLL029W 22.97 0.99 3 180.7591 1 YLL029W YLL029W SGDID:S000003952,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLL029W is not an essential gene but mutant is defective in spore formation, Chr XII from 81460-83709, Uncharacterized ORF YDR161W 11.66 1.00 6 719.3787 1 YDR161W YDR161W SGDID:S000002568,interacts with PP2C, Chr IV from 779040-780203, Uncharacterized ORF YOL021C 41.179 1.00 4 135.7966 1 YOL021C DIS3 SGDID:S000005381,Nucleolar exosome component, involved in rRNA processing and RNA degradation, binds Gsp1p\Ran and enhances the GEF activity of Srm1p, implicated in mitotic control, homologous to the E. coli RNase R of the RNase II family, Chr XV from 285427-282422, reverse complement, Verified ORF YNL299W 26.97 0.83 2 86.0462 1 YNL299W TRF5 SGDID:S000005243,Poly (A) polymerase involved in nuclear RNA quality control based on: homology with Trf4p, genetic interactions with TRF4 mutants, physical interaction with Mtr4p (TRAMP subunit), and by direct assay; disputed role as a sigma DNA polymerase, Chr XIV from 66517-68445, Verified ORF Q0255 25.44 0.76 3 125.2918 1 Q0255 Q0255 SGDID:S000007282,Hypothetical protein, Chr Mito from 74495-75622,75663-75872,75904-75984, Uncharacterized ORF YOL144W 24.33 1.00 5 287.2981 1 YOL144W NOP8 SGDID:S000005504,Nucleolar protein required for 60S ribosomal subunit biogenesis, Chr XV from 53097-54551, Verified ORF YGL111W 23.839 0.98 1 57.4702 1 YGL111W NSA1 SGDID:S000003079,Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis, Chr VII from 299981-301372, Verified ORF YBR181C 13.36 1.00 335 35054.4583 2 YBR181C,YPL090C RPS6B SGDID:S000000385,Protein component of the small (40S) ribosomal subunit; identical to Rps6Ap and has similarity to rat S6 ribosomal protein, Chr II from 592769-592764,592411-591707, reverse complement, Verified ORF YNL055C 15.89 1.00 189 16628.1073 1 YNL055C POR1 SGDID:S000005000,Mitochondrial porin (voltage-dependent anion channel), outer membrane protein required for the maintenance of mitochondrial osmotic stability and mitochondrial membrane permeability, Chr XIV from 518846-517995, reverse complement, Verified ORF YMR033W 22.27 0.95 2 119.2719 1 YMR033W ARP9 SGDID:S000004636,Actin-related protein involved in transcriptional regulation; subunit of the chromatin remodeling Snf\Swi complex, Chr XIII from 337787-337816,337903-339276, Verified ORF YJR159W 18.839 0.86 3 191.455 1 YJR159W SOR1 SGDID:S000003920,Sorbitol dehydrogenase; expression is induced in the presence of sorbitol, Chr X from 735960-737033, Verified ORF YOR285W 6.9 1.00 19 3849.5451 1 YOR285W YOR285W SGDID:S000005811,Protein of unknown function, localized to the mitochondrial outer membrane, Chr XV from 849634-850053, Verified ORF YGL039W 17.819 0.92 3 216.5362 1 YGL039W YGL039W SGDID:S000003007,Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol), Chr VII from 423967-425013, Verified ORF YNL147W 3.36 0.93 4 1547.7776 1 YNL147W LSM7 SGDID:S000005091,Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA, Chr XIV from 350942-350959,351080-351385, Verified ORF YLR325C 4.4 1.00 66 20969.8909 1 YLR325C RPL38 SGDID:S000004317,Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein, Chr XII from 781379-781143, reverse complement, Verified ORF YPR022C 34.548 0.93 17 639.7552 1 YPR022C YPR022C SGDID:S000006226,Hypothetical protein, Chr XVI from 607309-603908, reverse complement, Uncharacterized ORF YOR014W 22.06 1.00 5 316.8614 1 YOR014W RTS1 SGDID:S000005540,B-type regulatory subunit of protein phosphatase 2A (PP2A); homolog of the mammalian B' subunit of PP2A, Chr XV from 357674-359947, Verified ORF YLL022C 7.25 0.99 1 190.8983 1 YLL022C HIF1 SGDID:S000003945,Non-essential component of the HAT-B histone acetyltransferase complex (Hat1p-Hat2p-Hif1p), localized to the nucleus; has a role in telomeric silencing, Chr XII from 100200-99043, reverse complement, Verified ORF YDR238C 39.23 1.00 21 748.3519 1 YDR238C SEC26 SGDID:S000002646,Essential beta-coat protein of the COPI coatomer, involved in ER-to-Golgi protein trafficking and maintenance of normal ER morphology; shares 43% sequence identity with mammalian beta-coat protein (beta-COP), Chr IV from 940812-937891, reverse complement, Verified ORF YMR207C 99.0809999999999 0.87 3 36.826 1 YMR207C HFA1 SGDID:S000004820,Mitochondrial acetyl-coenzyme A carboxylase, catalyzes the production of malonyl-CoA in mitochondrial fatty acid biosynthesis, Chr XIII from 683563-677192, reverse complement, Verified ORF YOR266W 21.736 0.80 4 205.8141 1 YOR266W PNT1 SGDID:S000005792,Mitochondrial inner membrane protein involved in export of proteins from the mitochondrial matrix; overexpression of PNT1 confers resistance to the anti-Pneumocystis carinii drug pentamidine, and deletion confers increased sensitivity, Chr XV from 821022-822293, Verified ORF YNL231C 23 1.00 4 243.1291 1 YNL231C PDR16 SGDID:S000005175,Phosphatidylinositol transfer protein (PITP) controlled by the multiple drug resistance regulator Pdr1p, localizes to lipid particles and microsomes, controls levels of various lipids, may regulate lipid synthesis, homologous to Pdr17p, Chr XIV from 217043-215988, reverse complement, Verified ORF YBR286W 20.859 1.00 58 3887.2226 1 YBR286W APE3 SGDID:S000000490,Vacuolar aminopeptidase Y, processed to mature form by Prb1p, Chr II from 774696-776309, Verified ORF YNL248C 19.42 1.00 9 647.8854 1 YNL248C RPA49 SGDID:S000005192,RNA polymerase I subunit A49, Chr XIV from 182609-181362, reverse complement, Verified ORF YDR120C 25.68 1.00 29 1578.7301 1 YDR120C TRM1 SGDID:S000002527,tRNA methyltransferase, localizes to both the nucleus and mitochondrion to produce the modified base N2,N2-dimethylguanosine in tRNAs in both compartments, Chr IV from 693258-691546, reverse complement, Verified ORF YJL012C 31.076 1.00 106 4768.5425 1 YJL012C VTC4 SGDID:S000003549,Vacuolar membrane protein involved in vacuolar polyphosphate accumulation; functions as a regulator of vacuolar H+-ATPase activity and vacuolar transporter chaperones; involved in non-autophagic vacuolar fusion, Chr X from 413315-411150, reverse complement, Verified ORF YMR246W 20.639 1.00 34 2303.0065 1 YMR246W FAA4 SGDID:S000004860,Long chain fatty acyl-CoA synthetase, regulates protein modification during growth in the presence of ethanol, functions to incorporate palmitic acid into phospholipids and neutral lipids, Chr XIII from 759806-761890, Verified ORF YGL103W 11.66 1.00 206 24698.6708 1 YGL103W RPL28 SGDID:S000003071,Ribosomal protein L29 of the large (60S) ribosomal subunit, has similarity to E. coli L15 and rat L27a ribosomal proteins; may have peptidyl transferase activity; can mutate to cycloheximide resistance, Chr VII from 310970-311018,311530-311930, Verified ORF YOR158W 14.747 0.97 1 91.9544 1 YOR158W PET123 SGDID:S000005684,Mitochondrial ribosomal protein of the small subunit; PET123 exhibits genetic interactions with PET122, which encodes a COX3 mRNA-specific translational activator, Chr XV from 632165-633121, Verified ORF YNL007C 17.7 1.00 106 8372.1598 1 YNL007C SIS1 SGDID:S000004952,Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; not functionally redundant with Ydj1p due to due to substrate specificity; shares similarity with bacterial DnaJ proteins, Chr XIV from 619567-618509, reverse complement, Verified ORF YJL098W 45.38 1.00 11 338.8699 1 YJL098W SAP185 SGDID:S000003634,Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap155p, and Sap190p, Chr X from 242000-245176, Verified ORF YLR425W 47.359 1.00 13 383.7476 1 YLR425W TUS1 SGDID:S000004417,Guanine nucleotide exchange factor (GEF) that functions to modulate Rhop1 activity as part of the cell integrity signaling pathway; multicopy suppressor of tor2 mutation and ypk1 ypk2 double mutation; potential Cdc28p substrate, Chr XII from 982891-986814, Verified ORF YBR059C 40.21 1.00 11 382.4401 1 YBR059C AKL1 SGDID:S000000263,Ser-Thr protein kinase, member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization, Chr II from 360185-356859, reverse complement, Verified ORF YKL196C 12.517 1.00 12 1340.2502 1 YKL196C YKT6 SGDID:S000001679,Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in trafficking to and within the Golgi, endocytic trafficking to the vacuole, and vacuolar fusion; membrane localization due to prenylation at the carboxy-terminus, Chr XI from 75539-74937, reverse complement, Verified ORF YOR187W 20.43 1.00 27 1847.5674 1 YOR187W TUF1 SGDID:S000005713,Mitochondrial translation elongation factor Tu; comprises both GTPase and guanine nucleotide exchange factor activities, while these activities are found in separate proteins in S. pombe and humans, Chr XV from 684031-685344, Verified ORF YNL160W 6.49 0.81 2 348.9596 1 YNL160W YGP1 SGDID:S000005104,Cell wall-related secretory glycoprotein; induced by nutrient deprivation-associated growth arrest and upon entry into stationary phase; may be involved in adaptation prior to stationary phase entry; has similarity to Sps100p, Chr XIV from 336547-337611, Verified ORF YGR020C 5.9 1.00 11 2606.4271 1 YGR020C VMA7 SGDID:S000003252,Subunit F of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (