### CLUSTER 1 ### 03 Cell cycle & DNA processing SWH1 01 OSH2 steroid biosynthesis; plasma membrane; bud neck; 01 HBS1 protein biosynthesis; 05 CCA1 tRNA modification; nucleus; cytoplasm; mitochondrial matrix; 04 MAG1 DNA dealkylation; nucleus; 03 YPL071C UFE1 retrograde (Golgi to ER) transport; nonselective vesicle fusion; endoplasmic reticulum membrane; 14 08 ARL3 intracellular protein transport; soluble fraction; nuclear envelope-endoplasmic reticulum network; 08 06 MCM2 pre-replicative complex formation and maintenance; DNA unwinding; DNA replication initiation; nucleus; pre-replicative complex; cytoplasm; 03 MCM3 pre-replicative complex formation and maintenance; DNA unwinding; DNA replication initiation; nucleus; pre-replicative complex; cytoplasm; 03 CDC47 pre-replicative complex formation and maintenance; DNA unwinding; DNA replication initiation; nucleus; pre-replicative complex; cytoplasm; 03 MCM10 DNA replication initiation; DNA strand elongation; nucleus; 03 CDC46 pre-replicative complex formation and maintenance; DNA unwinding; DNA replication initiation; establishment of chromatin silencing; pre-replicative complex; replication fork; cytoplasm; 03 CDC45 pre-replicative complex formation and maintenance; DNA replication initiation; DNA strand elongation; pre-replicative complex; replication fork; 03 YNL234W response to stress; PET127 RNA processing; mitochondrial membrane; 05 ECI1 fatty acid beta-oxidation; peroxisome; 01 02 COS111 signal transduction; 10 YFL042C VID30 regulation of nitrogen utilization; negative regulation of gluconeogenesis; 06 MTO1 protein biosynthesis; mitochondrion; 05 YER080W RIM8 invasive growth; meiosis; protein processing; ESC2 chromatin silencing at HML and HMR (sensu Saccharomyces); nucleus; 04 YPL113C metabolism; 01 MCH5 transport; membrane; YGL185C metabolism; YOR390W PHO91 phosphate transport; membrane; 01 13 YKR106W transport; membrane; 11 YIL057C MUP3 amino acid transport; membrane; 01 08 DAN4 cell wall (sensu Fungi); YNL129W YEL070W 01 YDR316W ULA1 protein neddylation; 06 YPL088W aldehyde metabolism; 02 01 SPR1 sporulation (sensu Saccharomyces); cell wall (sensu Fungi); 14 01 YPL264C integral to membrane; DDC1 cell cycle checkpoint; meiosis; condensed nuclear chromosome; 03 11 FDH1 NADH regeneration; formate catabolism; cytosol; 02 TFB1 nucleotide-excision repair\, DNA duplex unwinding; nucleotide-excision repair; transcription initiation from Pol II promoter; negative regulation of transcription from Pol II promoter\, mitotic; nucleotide excision repair factor 3 complex; transcription factor TFIIH complex; 04 03 RAD52 meiotic DNA recombinase assembly; telomerase-independent telomere maintenance; double-strand break repair via break-induced replication; DNA recombinase assembly; double-strand break repair via single-strand annealing; double-strand break repair via synthesis-dependent strand annealing; nuclear chromosome; nucleus; 03 14 RAD14 nucleotide-excision repair\, DNA damage recognition; nucleotide excision repair factor 1 complex; 03 RAD10 removal of nonhomologous ends; double-strand break repair via single-strand annealing\, removal of nonhomologous ends; nucleotide-excision repair\, DNA incision\, 5' to lesion; nucleotide excision repair factor 1 complex; 03 REV1 DNA dependent DNA replication; DNA repair; nucleus; 03 YAL027W DED1 translational initiation; cytoplasm; 04 05 MSH2 removal of nonhomologous ends; mismatch repair; DNA recombination; mitotic recombination; nuclear chromosome; 03 RAD26 transcription-coupled nucleotide-excision repair; nucleotide-excision repair; nucleus; 03 SSL2 nucleotide-excision repair\, DNA duplex unwinding; transcription initiation from Pol II promoter; negative regulation of transcription from Pol II promoter\, mitotic; nucleotide excision repair factor 3 complex; transcription factor TFIIH complex; 03 04 RAD7 nucleotide-excision repair\, DNA damage recognition; repairosome; nucleotide excision repair factor 4 complex; 03 RAD4 nucleotide-excision repair\, DNA damage recognition; repairosome; nucleotide excision repair factor 2 complex; 03 RAD16 nucleotide-excision repair\, DNA damage recognition; repairosome; nucleotide excision repair factor 4 complex; 03 RAD3 nucleotide-excision repair\, DNA duplex unwinding; transcription initiation from Pol II promoter; negative regulation of transcription from Pol II promoter\, mitotic; nucleotide excision repair factor 3 complex; transcription factor TFIIH complex; 04 03 RAD2 nucleotide-excision repair\, DNA incision\, 3' to lesion; nucleotide excision repair factor 3 complex; 03 RAD23 nucleotide-excision repair\, DNA damage recognition; negative regulation of protein catabolism; repairosome; nucleotide excision repair factor 2 complex; 03 XRS2 double-strand break repair via break-induced replication; double-strand break repair via nonhomologous end-joining; meiotic DNA double-strand break formation; nucleus; 03 RAD59 telomerase-independent telomere maintenance; double-strand break repair via break-induced replication; double-strand break repair via single-strand annealing; nucleus; 03 RAD57 meiotic DNA recombinase assembly; telomerase-independent telomere maintenance; double-strand break repair via break-induced replication; DNA recombinase assembly; double-strand break repair via single-strand annealing; double-strand break repair via synthesis-dependent strand annealing; nucleus; 14 03 RAD55 meiotic DNA recombinase assembly; double-strand break repair via break-induced replication; DNA recombinase assembly; double-strand break repair via single-strand annealing; double-strand break repair via synthesis-dependent strand annealing; nucleus; 03 14 RAD51 meiotic joint molecule formation; telomerase-independent telomere maintenance; double-strand break repair via break-induced replication; chromatin modeling; heteroduplex formation; strand invasion; double-strand break repair via single-strand annealing; double-strand break repair via synthesis-dependent strand annealing; nuclear chromosome; condensed nuclear chromosome; 14 03 RAD54 telomerase-independent telomere maintenance; double-strand break repair via break-induced replication; chromatin modeling; heteroduplex formation; double-strand break repair via single-strand annealing; double-strand break repair via synthesis-dependent strand annealing; nucleus; 03 RFA3 DNA unwinding; DNA replication\, priming; DNA strand elongation; nucleotide-excision repair; postreplication repair; double-strand break repair; DNA recombination; DNA replication factor A complex; 03 RFA1 DNA unwinding; DNA replication\, priming; DNA strand elongation; nucleotide-excision repair; postreplication repair; double-strand break repair; DNA recombination; DNA replication factor A complex; 14 03 MLH2 DNA repair; nucleus; 03 MSH5 meiotic recombination; nucleus; 03 MSH4 meiotic recombination; nuclear chromosome; 03 MSH1 DNA repair; mitochondrion; 03 MSH6 mismatch repair; nucleus; 03 MLH1 meiotic recombination; nucleus; 03 POL30 leading strand elongation; lagging strand elongation; mutagenesis; base-excision repair; nucleotide-excision repair; mismatch repair; postreplication repair; replication fork; 03 RAD27 DNA repair synthesis; DNA replication; DNA repair; nucleus; 03 SMA2 spore wall assembly (sensu Saccharomyces); PMS1 mismatch repair; meiosis; nuclear chromosome; 03 ESC8 chromatin silencing; nucleus; RAD9 regulation of cell cycle; DNA damage response\, signal transduction resulting in cell cycle arrest; DNA repair; nucleotide-excision repair; positive regulation of transcription from Pol II promoter; nucleus; 03 04 TEL1 response to DNA damage stimulus; telomerase-dependent telomere maintenance; nucleus; 01 03 MEC1 DNA replication checkpoint; DNA damage response\, signal transduction resulting in cell cycle arrest; nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism; DNA recombination; meiotic recombination; nucleus; 03 DUN1 cell cycle checkpoint; DNA damage response\, signal transduction resulting in cell cycle arrest; protein amino acid phosphorylation; 10 03 DBF4 DNA replication initiation; regulation of DNA replication; protein amino acid phosphorylation; nucleoplasm; 03 PTC2 DNA damage response\, signal transduction resulting in cell cycle arrest; regulation of CDK activity; G1/S transition of mitotic cell cycle; inactivation of MAPK (osmolarity sensing); protein amino acid dephosphorylation; response to unfolded protein; ASF1 DNA damage response\, signal transduction resulting in induction of apoptosis; chromatin assembly complex; 04 RAD50 meiotic DNA double-strand break processing; telomerase-independent telomere maintenance; double-strand break repair via break-induced replication; double-strand break repair via nonhomologous end-joining; meiotic DNA double-strand break formation; nucleus; 03 RAD17 DNA damage response\, signal transduction resulting in cell cycle arrest; meiotic recombination; nucleus; 03 MEC3 DNA damage response\, signal transduction resulting in cell cycle arrest; DNA metabolism; chromatin silencing at telomere; nucleus; 03 RAD24 DNA damage response\, signal transduction resulting in cell cycle arrest; nucleotide-excision repair; meiotic recombination; nucleus; 03 POL2 DNA repair synthesis; leading strand elongation; lagging strand elongation; nucleotide-excision repair; mismatch repair; replication fork; 03 PRI2 DNA repair synthesis; DNA replication\, priming; DNA replication initiation; lagging strand elongation; alpha DNA polymerase\:primase complex; 03 DPB11 DNA replication initiation; leading strand elongation; lagging strand elongation; nucleotide-excision repair; mismatch repair; replication fork; 03 DPB4 leading strand elongation; lagging strand elongation; epsilon DNA polymerase complex; 04 CTF18 sister chromatid cohesion; DNA replication factor C complex; 03 DPB3 leading strand elongation; lagging strand elongation; nucleotide-excision repair; mismatch repair; replication fork; 03 REV3 mutagenesis; DNA repair; nucleus; 03 PSD1 phosphatidylcholine biosynthesis; mitochondrion; mitochondrial inner membrane; 01 TAT2 aromatic amino acid transport; plasma membrane; 08 01 POL32 leading strand elongation; lagging strand elongation; mutagenesis; base-excision repair; nucleotide-excision repair; mismatch repair; postreplication repair; nucleus; delta DNA polymerase complex; 03 PRI1 DNA replication\, priming; DNA replication initiation; lagging strand elongation; alpha DNA polymerase\:primase complex; 03 POL12 DNA replication\, priming; DNA replication initiation; lagging strand elongation; alpha DNA polymerase\:primase complex; 03 SPT16 chromatin modeling; regulation of global transcription from Pol II promoter; RNA elongation from Pol II promoter; nuclear chromatin; alpha DNA polymerase\:primase complex; transcription elongation factor complex; 03 POB3 DNA dependent DNA replication; chromatin assembly/disassembly; chromatin modeling; nucleus; 04 03 YBR070C 11 DNA2 DNA dependent DNA replication; lagging strand elongation; DNA repair; nucleus; 03 CDC9 DNA ligation; lagging strand elongation; base-excision repair; nucleotide-excision repair; DNA recombination; replication fork; 03 FUN11 STN1 telomere capping; nuclear telomere cap complex; 03 RPR2 tRNA processing; nucleolar ribonuclease P complex; 04 CDC13 telomere maintenance; telomere capping; nuclear telomere cap complex; 03 04 YDR540C SCC2 mitotic sister chromatid cohesion; nuclear cohesin complex; 03 YEL016C RTT109 negative regulation of DNA transposition; SMC1 mitotic chromosome segregation; nuclear cohesin complex; 03 IRR1 cytogamy; mitotic sister chromatid cohesion; colony morphology; germination (sensu Saccharomyces); nuclear cohesin complex; 03 14 SMC2 mitotic chromosome segregation; mitotic chromosome condensation; nuclear condensin complex; 03 MCD1 mitotic sister chromatid cohesion; mitotic chromosome condensation; nuclear cohesin complex; 03 RAX2 bud site selection; bud scar; bud neck; membrane; ECO1 DNA replication; DNA repair; sister chromatid cohesion; nuclear chromatin; 03 YDL156W DCC1 sister chromatid cohesion; DNA replication factor C complex; 03 RFC5 leading strand elongation; mismatch repair; sister chromatid cohesion; DNA replication factor C complex; 03 CTF8 sister chromatid cohesion; DNA replication factor C complex; RFC3 leading strand elongation; mismatch repair; sister chromatid cohesion; nucleus; DNA replication factor C complex; 03 RFC2 cell cycle checkpoint; leading strand elongation; mismatch repair; sister chromatid cohesion; DNA replication factor C complex; 03 YLR407W YJL160C 14 11 SAE3 meiotic recombination; 03 GOD1 ARP7 chromatin modeling; nucleus; nucleosome remodeling complex; SWI/SNF complex; ZIP1 meiosis; synapsis; synaptonemal complex; 03 SPO11 meiotic DNA double-strand break formation; nuclear chromosome; 03 MEI4 meiotic recombination; sporulation (sensu Fungi); meiotic DNA double-strand break formation; 14 03 SPO13 positive regulation of sister chromatid cohesion; nucleus; 03 REC104 meiotic recombination; meiotic DNA double-strand break formation; 03 REC107 meiotic recombination; 03 HOP1 meiosis; synaptonemal complex formation; condensed nuclear chromosome; synaptonemal complex; 03 RED1 synaptonemal complex formation; synaptonemal complex; 03 YGR131W 08 MIG3 transcription initiation; nucleus; 04 YBL029W SAG1 agglutination during conjugation with cellular fusion; cell wall (sensu Fungi); 14 ASP3-3 asparagine catabolism; cellular response to nitrogen starvation; periplasmic space (sensu Fungi); 01 YIL166C transport; membrane; QDR1 multidrug transport; plasma membrane; integral to plasma membrane; 11 REC102 meiotic recombination; meiotic DNA double-strand break formation; nucleus; 03 SSK2 activation of MAPKK (osmolarity sensing); protein amino acid phosphorylation; osmosensory signaling pathway; actin cytoskeleton organization and biogenesis; cytosol; 11 13 HES1 steroid biosynthesis; 01 INP52 endocytosis; cell wall organization and biogenesis; dephosphorylation; membrane fraction; actin cortical patch (sensu Saccharomyces); 01 RAS1 G-protein signaling\, adenylate cyclase activating pathway; RAS protein signal transduction; cell proliferation; plasma membrane; 01 14 13 03 10 MER1 meiosis; nucleus; 03 04 YKU70 telomere maintenance; double-strand break repair via homologous recombination; double-strand break repair via nonhomologous end-joining; chromatin assembly/disassembly; transcriptional gene silencing; nuclear chromatin; nuclear membrane; nuclear telomeric heterochromatin; 03 YKU80 telomere maintenance; double-strand break repair via homologous recombination; double-strand break repair via nonhomologous end-joining; chromatin assembly/disassembly; transcriptional gene silencing; nuclear chromatin; nuclear telomeric heterochromatin; 03 MRE11 meiotic DNA double-strand break processing; double-strand break repair via break-induced replication; DNA repair; double-strand break repair via nonhomologous end-joining; meiotic DNA double-strand break formation; nucleus; 03 ARO8 aromatic amino acid family metabolism; 01 ARO10 leucine catabolism; phenylalanine catabolism; 01 02 NPY1 NADH metabolism; cytoplasm; peroxisome; 01 ALG2 oligosaccharide-lipid intermediate assembly; endoplasmic reticulum; 06 01 YGL015C PEA2 establishment of cell polarity (sensu Saccharomyces); actin filament organization; polar budding; Rho protein signal transduction; polarisome; actin cap (sensu Saccharomyces); 14 MKK1 protein amino acid phosphorylation; signal transduction; bud tip; 14 03 11 BUL1 mitochondrion inheritance; protein polyubiquitination; protein monoubiquitination; plasma membrane; 06 SLT2 protein amino acid phosphorylation; cell wall organization and biogenesis; signal transduction; nucleus; cytoplasm; bud tip; 14 11 13 03 SPH1 establishment of cell polarity (sensu Saccharomyces); actin filament organization; polar budding; pseudohyphal growth; Rho protein signal transduction; incipient bud site; polarisome; bud tip; bud neck; shmoo tip; 14 SPA2 establishment of cell polarity (sensu Saccharomyces); actin filament organization; polar budding; pseudohyphal growth; Rho protein signal transduction; incipient bud site; polarisome; bud tip; bud neck; shmoo tip; 14 13 BCK1 establishment of cell polarity (sensu Saccharomyces); protein amino acid phosphorylation; protein kinase cascade; response to nutrients; intracellular; 14 11 03 SSN3 negative regulation of transcription from Pol II promoter; protein amino acid phosphorylation; meiosis; regulation of transcription; transcription factor complex; 01 04 03 RDR1 response to xenobiotic stimulus; nucleus; MEK1 protein amino acid phosphorylation; meiosis; nucleus; 03 GRE2 response to stress; nucleus; cytoplasm; 01 BNR1 response to osmotic stress; actin filament organization; axial budding; contractile ring (sensu Saccharomyces); 14 HOF1 cytokinesis; contractile ring (sensu Saccharomyces); 03 14 BUD6 bud site selection; establishment of cell polarity (sensu Saccharomyces); cytokinesis; response to osmotic stress; actin filament organization; polar budding; Rho protein signal transduction; polarisome; actin cap (sensu Saccharomyces); 14 DBR1 RNA catabolism; snoRNA metabolism; nucleus; 14 01 BUD8 bud site selection; pseudohyphal growth; incipient bud site; bud tip; 14 DFG10 pseudohyphal growth; 14 DCD1 pyrimidine nucleotide metabolism; 01 TOP3 regulation of DNA recombination; telomerase-dependent telomere maintenance; meiotic recombination; nucleus; 03 YBR161W 14 TVP18 APC1 mitotic spindle elongation; mitotic chromosome segregation; ubiquitin-dependent protein catabolism; mitotic metaphase/anaphase transition; cyclin catabolism; anaphase-promoting complex; 03 06 ALG8 dolichol-linked oligosaccharide biosynthesis; oligosaccharide-lipid intermediate assembly; endoplasmic reticulum membrane; 01 06 YMR299C APC2 mitotic spindle elongation; mitotic chromosome segregation; ubiquitin-dependent protein catabolism; mitotic metaphase/anaphase transition; cyclin catabolism; anaphase-promoting complex; 03 06 DOC1 mitotic spindle elongation; mitotic chromosome segregation; ubiquitin-dependent protein catabolism; mitotic metaphase/anaphase transition; cyclin catabolism; anaphase-promoting complex; 03 06 CDC26 mitotic spindle elongation; mitotic chromosome segregation; ubiquitin-dependent protein catabolism; mitotic metaphase/anaphase transition; cyclin catabolism; anaphase-promoting complex; 06 03 CDC27 mitotic spindle elongation; mitotic chromosome segregation; ubiquitin-dependent protein catabolism; mitotic metaphase/anaphase transition; cyclin catabolism; anaphase-promoting complex; 03 06 APC11 mitotic spindle elongation; mitotic chromosome segregation; ubiquitin-dependent protein catabolism; mitotic metaphase/anaphase transition; cyclin catabolism; anaphase-promoting complex; 03 06 APC4 mitotic spindle elongation; mitotic chromosome segregation; ubiquitin-dependent protein catabolism; mitotic metaphase/anaphase transition; cyclin catabolism; anaphase-promoting complex; 03 06 CDC16 mitotic spindle elongation; mitotic chromosome segregation; ubiquitin-dependent protein catabolism; mitotic metaphase/anaphase transition; cyclin catabolism; anaphase-promoting complex; 03 06 APC9 mitotic spindle elongation; mitotic chromosome segregation; ubiquitin-dependent protein catabolism; mitotic metaphase/anaphase transition; cyclin catabolism; anaphase-promoting complex; 03 06 CDC23 mitotic spindle elongation; mitotic chromosome segregation; ubiquitin-dependent protein catabolism; mitotic metaphase/anaphase transition; cyclin catabolism; anaphase-promoting complex; 03 06 SPT2 negative regulation of transcription from Pol II promoter; nucleus; 04 NBP2 06 BUB2 mitotic spindle checkpoint; spindle pole body; 03 14 MAD1 nucleocytoplasmic transport; mitotic spindle checkpoint; nucleus; nuclear pore; 03 YIL023C Q0092 MAD3 mitotic spindle checkpoint; nucleus; 03 BUB1 protein amino acid phosphorylation; mitotic spindle checkpoint; kinetochore; condensed nuclear chromosome kinetochore; nucleus; 03 YGR153W CDC7 DNA replication initiation; regulation of DNA replication; protein amino acid phosphorylation; nucleoplasm; 03 AMA1 meiosis I; sporulation (sensu Saccharomyces); protein catabolism; anaphase-promoting complex; 14 CDC15 cytokinesis; protein amino acid phosphorylation; regulation of exit from mitosis; spindle pole body; bud neck; 03 CDC14 protein amino acid dephosphorylation; regulation of exit from mitosis; nucleus; nucleolus; spindle pole body; 03 BFA1 conjugation with cellular fusion; mitotic spindle checkpoint; spindle pole body; 03 DEM1 CDC3 establishment of cell polarity (sensu Saccharomyces); cellular morphogenesis; cytokinesis; cell wall organization and biogenesis; axial budding; septin ring (sensu Saccharomyces); spore wall (sensu Fungi); prospore membrane; shmoo tip; 14 03 ADE13 purine base metabolism; 01 PDR17 phospholipid biosynthesis; phospholipid transport; response to drug; cytoplasm; 01 UBC9 mitotic spindle elongation; G2/M transition of mitotic cell cycle; protein modification; nucleus; 06 03 SIZ1 protein sumoylation; septin ring; 06 SHS1 establishment of cell polarity (sensu Saccharomyces); cellular morphogenesis; cytokinesis; septin ring; 14 03 CDC10 establishment of cell polarity (sensu Saccharomyces); conjugation with cellular fusion; cellular morphogenesis during conjugation with cellular fusion; cellular morphogenesis; cytokinesis; cell wall organization and biogenesis; axial budding; polar budding; spore wall assembly (sensu Saccharomyces); septin ring (sensu Saccharomyces); 01 03 14 CDC12 establishment of cell polarity (sensu Saccharomyces); conjugation with cellular fusion; cellular morphogenesis; cytokinesis; cell wall organization and biogenesis; axial budding; polar budding; septin ring (sensu Saccharomyces); cytoplasm; 14 03 01 KCC4 septin checkpoint; septin ring assembly; protein amino acid phosphorylation; bud growth; axial budding; bud neck; 03 GIN4 septin checkpoint; septin ring assembly; protein amino acid phosphorylation; bud growth; axial budding; bud neck; 14 03 CDC8 dTDP biosynthesis; dTTP biosynthesis; DNA dependent DNA replication; plasmid maintenance; mutagenesis; DNA repair; nucleus; cytoplasm; 01 HSL1 regulation of cell cycle; cell morphogenesis checkpoint; G2/M transition of mitotic cell cycle; septin checkpoint; protein amino acid phosphorylation; bud neck; septin ring; 03 14 CDC11 establishment of cell polarity (sensu Saccharomyces); conjugation with cellular fusion; cellular morphogenesis; cytokinesis; cell wall organization and biogenesis; axial budding; septin ring (sensu Saccharomyces); spore wall (sensu Fungi); prospore membrane; shmoo tip; 14 03 01 AFR1 signal transduction during conjugation with cellular fusion; regulation of G-protein coupled receptor protein signaling pathway; shmoo tip; 14 ROT2 cell wall biosynthesis (sensu Fungi); endoplasmic reticulum; 02 01 RAM1 protein amino acid farnesylation; protein farnesyltransferase complex; 06 01 10 CDC43 establishment of cell polarity (sensu Saccharomyces); calcium ion homeostasis; small GTPase mediated signal transduction; protein amino acid geranylgeranylation; intracellular; 01 06 03 14 STE14 peptide pheromone maturation; endoplasmic reticulum membrane; 01 06 RAM2 peptide pheromone maturation; protein amino acid farnesylation; protein amino acid geranylgeranylation; protein farnesyltransferase complex; 06 01 MAD2 mitotic spindle checkpoint; condensed nuclear chromosome kinetochore; nuclear pore; 03 MSB2 establishment of cell polarity (sensu Saccharomyces); response to osmotic stress; integral to plasma membrane; 14 BUD4 bud site selection; axial budding; contractile ring (sensu Saccharomyces); 14 BUD5 bud site selection; axial budding; polar budding; pseudohyphal growth; small GTPase mediated signal transduction; incipient bud site; bud neck; 14 BUD3 bud site selection; cytokinesis; axial budding; contractile ring (sensu Saccharomyces); 14 BOI1 establishment of cell polarity (sensu Saccharomyces); Rho protein signal transduction; site of polarized growth (sensu Saccharomyces); bud; bud neck; 14 CDC24 establishment of cell polarity (sensu Saccharomyces); signal transduction during conjugation with cellular fusion; cellular morphogenesis during conjugation with cellular fusion; chitin localization; apical bud growth; isotropic bud growth; pseudohyphal growth; invasive growth; small GTPase mediated signal transduction; incipient bud site; nucleus; bud neck; shmoo tip; 14 03 13 BEM1 establishment of cell polarity (sensu Saccharomyces); cellular morphogenesis during conjugation with cellular fusion; incipient bud site; bud tip; bud neck; 14 03 RDI1 actin filament organization; small GTPase mediated signal transduction; cytosol; 14 BEM2 microtubule cytoskeleton organization and biogenesis; establishment of cell polarity (sensu Saccharomyces); cell wall organization and biogenesis; bud growth; small GTPase mediated signal transduction; actin cytoskeleton organization and biogenesis; intracellular; 14 03 GIC1 establishment of cell polarity (sensu Saccharomyces); axial budding; Rho protein signal transduction; incipient bud site; actin cap (sensu Saccharomyces); bud tip; bud neck; 13 14 BUD2 bud site selection; axial budding; polar budding; small GTPase mediated signal transduction; intracellular; 14 GIC2 establishment of cell polarity (sensu Saccharomyces); axial budding; Rho protein signal transduction; incipient bud site; actin cap (sensu Saccharomyces); bud tip; shmoo tip; 14 13 STE20 bud site selection; signal transduction during conjugation with cellular fusion; protein amino acid phosphorylation; pseudohyphal growth; incipient bud site; shmoo tip; 13 14 MFA1 signal transduction during conjugation with cellular fusion; extracellular; soluble fraction; 14 13 YDR319C MPT5 mRNA catabolism\, deadenylation-dependent; re-entry into mitotic cell cycle after pheromone arrest; loss of chromatin silencing during replicative cell aging; protein targeting; cell wall organization and biogenesis; 03 14 13 11 YJL057C YDL186W YDL180W VPS25 protein-vacuolar targeting; negative regulation of transcription by glucose; endosome; STE3 signal transduction during conjugation with cellular fusion; integral to plasma membrane; 10 13 14 PLP1 positive regulation of transcription from Pol II promoter by pheromones; cytoplasm; 13 FUS1 conjugation with cellular fusion; plasma membrane; shmoo tip; 14 13 STE7 signal transduction during conjugation with cellular fusion; protein amino acid phosphorylation; pseudohyphal growth; cytoplasm; shmoo tip; 14 13 STE5 signal transduction during conjugation with cellular fusion; nucleus; cytoplasm; plasma membrane; shmoo tip; 13 14 FUS3 signal transduction during conjugation with cellular fusion; protein amino acid phosphorylation; cell cycle arrest; nucleus; cytoplasm; shmoo tip; 13 03 14 STE12 conjugation with cellular fusion; pseudohyphal growth; invasive growth; positive regulation of transcription from Pol II promoter by pheromones; nucleus; 14 13 04 STE2 response to pheromone during conjugation with cellular fusion; formation of a cell surface projection; integral to plasma membrane; 14 13 10 GPA1 signal transduction during conjugation with cellular fusion; heterotrimeric G-protein complex; plasma membrane; 14 10 13 KSS1 signal transduction during conjugation with cellular fusion; protein amino acid phosphorylation; cell cycle arrest; pseudohyphal growth; nucleus; 14 13 STE18 signal transduction during conjugation with cellular fusion; cytoplasm; heterotrimeric G-protein complex; plasma membrane; 10 13 14 AKR1 signal transduction during conjugation with cellular fusion; endocytosis; protein amino acid palmitoylation; membrane; 13 14 STE50 MAPKKK cascade (osmolarity sensing); MAPKKK cascade (pseudohyphal growth); signal transduction during conjugation with cellular fusion; response to pheromone; cytoplasm; 13 14 YDR415C 06 TEC1 pseudohyphal growth; positive regulation of transcription from Pol II promoter; nucleus; 14 04 DIG2 invasive growth; nucleus; 14 SYG1 signal transduction; plasma membrane; 14 13 SST2 adaptation to pheromone during conjugation with cellular fusion; signal transduction; plasma membrane; 14 06 13 RAV2 vacuolar acidification; hydrogen-transporting ATPase V1 domain; SKP1 G1/S transition of mitotic cell cycle; G2/M transition of mitotic cell cycle; ubiquitin-dependent protein catabolism; nuclear ubiquitin ligase complex; kinetochore; nucleus; cytoplasm; SCF ubiquitin ligase complex; 01 06 03 CDC53 G1/S transition of mitotic cell cycle; G2/M transition of mitotic cell cycle; ubiquitin-dependent protein catabolism; nuclear ubiquitin ligase complex; SCF ubiquitin ligase complex; 01 06 03 CDC34 G1/S transition of mitotic cell cycle; G2/M transition of mitotic cell cycle; ubiquitin-dependent protein catabolism; nuclear ubiquitin ligase complex; nucleus; cytoplasm; 01 06 03 YIL001W CDC4 G1/S transition of mitotic cell cycle; G2/M transition of mitotic cell cycle; ubiquitin-dependent protein catabolism; ubiquitin ligase complex; nucleus; 14 03 YOL007C 01 IPT1 mannosyl diphosphorylinositol ceramide metabolism; membrane fraction; 01 YNL300W cell wall (sensu Fungi); AXL2 bud site selection; axial budding; integral to plasma membrane; bud; bud neck; septin ring; 14 FAR1 signal transduction during conjugation with cellular fusion; cell cycle arrest; nucleus; cytoplasm; 14 13 03 SWI6 G1/S-specific transcription in mitotic cell cycle; transcription; meiosis; nucleus; cytoplasm; 03 04 GRR1 G1/S transition of mitotic cell cycle; ubiquitin-dependent protein catabolism; contractile ring (sensu Saccharomyces); nuclear ubiquitin ligase complex; nucleus; cytoplasm; 01 14 03 08 11 PHO85 glycogen metabolism; protein amino acid phosphorylation; phosphate metabolism; cell cycle; nucleus; 01 04 03 02 DIG1 invasive growth; nucleus; 14 YOL019W STE4 signal transduction during conjugation with cellular fusion; heterotrimeric G-protein complex; plasma membrane; shmoo tip; 14 13 10 SVS1 response to chemical substance; 11 MSG5 adaptation to pheromone during conjugation with cellular fusion; 03 05 13 14 TOS2 bud tip; bud neck; 14 SWI5 G1-specific transcription in mitotic cell cycle; nucleus; cytoplasm; 14 04 MUS81 DNA repair; meiotic recombination; nucleus; 03 ESP1 regulation of exit from mitosis; mitotic sister chromatid separation; nucleus; cytoplasm; spindle; 03 MIH1 regulation of CDK activity; G2/M transition of mitotic cell cycle; 03 FPR1 06 TEM1 M phase of mitotic cell cycle; signal transduction; spindle pole body; 03 10 RAD53 nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism; DNA repair; nucleus; 10 03 IPL1 chromosome segregation; kinetochore microtubule; spindle microtubule; 03 PHM6 YHL029C CLN2 regulation of CDK activity; re-entry into mitotic cell cycle after pheromone arrest; nucleus; cytoplasm; 03 14 YPL267W CLB2 regulation of CDK activity; G2/M transition of mitotic cell cycle; nucleus; cytoplasm; 14 03 YPL141C MRPL50 protein biosynthesis; mitochondrial large ribosomal subunit; 05 CLB4 regulation of CDK activity; G1/S transition of mitotic cell cycle; G2/M transition of mitotic cell cycle; 03 UBI4 protein polyubiquitination; protein monoubiquitination; response to stress; sporulation (sensu Saccharomyces); protein deubiquitination; cytoplasm; 05 11 06 14 NAP1 M phase of mitotic cell cycle; nucleosome assembly; nucleus; 03 14 06 SWE1 cell morphogenesis checkpoint; regulation of CDK activity; G2/M transition of mitotic cell cycle; regulation of meiosis; nucleus; bud neck; 03 14 CDC5 DNA dependent DNA replication; protein amino acid phosphorylation; spindle pole; nucleus; bud neck; 03 CDH1 mitotic spindle elongation; mitotic chromosome segregation; ubiquitin-dependent protein catabolism; mitotic metaphase/anaphase transition; cyclin catabolism; regulation of cell size; nucleus; anaphase-promoting complex; cytoplasm; 03 06 CDC20 mitotic spindle elongation; mitotic chromosome segregation; ubiquitin-dependent protein catabolism; mitotic metaphase/anaphase transition; cyclin catabolism; anaphase-promoting complex; 06 03 ACE2 G1-specific transcription in mitotic cell cycle; nucleus; cytosol; 01 03 04 ALK1 mitosis; nucleus; 11 SIC1 regulation of CDK activity; G1/S transition of mitotic cell cycle; nucleus; cytoplasm; 03 SWI4 G1/S transition of mitotic cell cycle; transcription; cell cycle; nucleus; 03 04 CLB3 regulation of CDK activity; G1/S transition of mitotic cell cycle; G2/M transition of mitotic cell cycle; 03 CLB1 mitotic spindle assembly (sensu Saccharomyces); regulation of CDK activity; G2/M transition of mitotic cell cycle; meiotic G2/MI transition; 03 CLB6 regulation of CDK activity; G1/S transition of mitotic cell cycle; premeiotic DNA synthesis; 03 CKS1 regulation of cell cycle; 03 CDC28 regulation of cell cycle; G1/S transition of mitotic cell cycle; S phase of mitotic cell cycle; G2/M transition of mitotic cell cycle; protein amino acid phosphorylation; regulation of meiosis; nucleus; cytoplasm; 14 03 CLN3 regulation of CDK activity; G1/S transition of mitotic cell cycle; nucleus; 14 11 03 YHR035W IQG1 cytokinesis; response to osmotic stress; actin filament organization; contractile ring (sensu Saccharomyces); 14 03 YCR015C PDS1 protein-nucleus import; mitotic sister chromatid separation; nucleus; spindle; 03 PHO4 phosphate metabolism; cellular response to phosphate starvation; nucleus; cytoplasm; 01 04 PCL9 cell cycle; cyclin-dependent protein kinase holoenzyme complex; PHO80 regulation of phosphate metabolism; cyclin-dependent protein kinase holoenzyme complex; 01 04 PCL1 cell cycle; cyclin-dependent protein kinase holoenzyme complex; 03 PCL2 cell cycle; cyclin-dependent protein kinase holoenzyme complex; 03 YMR222C 01 YLR137W ARK1 actin cortical patch assembly; cytokinesis; protein amino acid phosphorylation; actin filament organization; actin cortical patch (sensu Saccharomyces); PCL10 regulation of glycogen biosynthesis; regulation of glycogen catabolism; cyclin-dependent protein kinase holoenzyme complex; 01 02 PCL6 regulation of glycogen biosynthesis; regulation of glycogen catabolism; cyclin-dependent protein kinase holoenzyme complex; CLG1 cell cycle; cyclin-dependent protein kinase holoenzyme complex; 03 PHO81 phosphate metabolism; 01 PCL5 cell cycle; cyclin-dependent protein kinase holoenzyme complex; STP4 04 01 PCL7 regulation of glycogen biosynthesis; regulation of glycogen catabolism; cyclin-dependent protein kinase holoenzyme complex; CLN1 regulation of CDK activity; nucleus; cytoplasm; 03 PHO5 phosphate metabolism; cellular response to phosphate starvation; cell wall (sensu Fungi); periplasmic space (sensu Fungi); 01 SPE4 spermine biosynthesis; pantothenate biosynthesis; 01 DCS2 MBP1 regulation of cell cycle; DNA replication; nucleus; 03 04 HSF1 regulation of transcription from Pol II promoter; response to stress; response to heat; nucleus; 03 04 11 RIM2 mitochondrial genome maintenance; mitochondrion; 02 08 YBL086C 01 LYS1 lysine biosynthesis\, aminoadipic pathway; cytoplasm; peroxisome; 01 YDR140W 06 TRM9 CCP1 response to oxidative stress; mitochondrion; mitochondrial intermembrane space; 11 NCR1 01 MET2 methionine biosynthesis; homoserine metabolism; cytoplasm; 01 DIT1 spore wall assembly (sensu Saccharomyces); 14 CKA2 G1/S transition of mitotic cell cycle; G2/M transition of mitotic cell cycle; flocculation; establishment of cell polarity (sensu Saccharomyces); regulation of transcription from Pol I promoter; regulation of transcription from Pol III promoter; protein amino acid phosphorylation; cell ion homeostasis; response to DNA damage stimulus; protein kinase CK2 complex; 03 04 14 MCM1 DNA replication initiation; regulation of transcription from Pol II promoter; nuclear chromatin; nucleus; 01 11 03 04 14 SHR3 amino acid transport; ER to Golgi transport; integral to endoplasmic reticulum membrane; 06 10 URK1 pyrimidine salvage; 01 PMA1 regulation of pH; proton transport; endoplasmic reticulum; plasma membrane; 13 YOR161C integral to plasma membrane; AGA1 agglutination during conjugation with cellular fusion; cell wall (sensu Fungi); 14 PCP1 mitochondrion organization and biogenesis; mitochondrial intermembrane space protein import; mitochondrion; 06 AFG3 protein complex assembly; proteolysis and peptidolysis; mitochondrial intermembrane space protein import; mitochondrial inner membrane; m-AAA complex; 06 YDL114W 03 RCK1 protein amino acid phosphorylation; regulation of meiosis; 03 YEL023C 14 GYP7 vesicle-mediated transport; YLR352W SNG1 response to drug; membrane; 11 HXT12 01 YLR156W HXT15 hexose transport; plasma membrane; 01 MRM2 rRNA modification; mitochondrion; 04 SSK1 osmosensory signaling pathway via two-component system; response to hydrogen peroxide; cytoplasm; 01 13 11 YPD1 response to osmotic stress; osmosensory signaling pathway via two-component system; cytoplasm; 13 SSK22 activation of MAPKK (osmolarity sensing); protein amino acid phosphorylation; osmosensory signaling pathway; 11 13 PTP3 inactivation of MAPK (osmolarity sensing); signal transduction during conjugation with cellular fusion; protein amino acid dephosphorylation; cytoplasm; 14 03 SLN1 protein amino acid phosphorylation; osmosensory signaling pathway via two-component system; response to hydrogen peroxide; plasma membrane; 10 13 01 11 PBS2 activation of MAPK (osmolarity sensing); protein amino acid phosphorylation; actin filament organization; osmosensory signaling pathway; cytoplasm; 01 13 11 SHO1 pseudohyphal growth; osmosensory signaling pathway via Sho1 osmosensor; plasma membrane; shmoo tip; 13 11 PTC1 mitochondrion inheritance; tRNA splicing; protein amino acid dephosphorylation; response to osmotic stress; nucleus; cytoplasm; 01 13 11 14 HSE1 protein-vacuolar targeting; endosome; 06 CUE3 DDI1 ubiquitin-dependent protein catabolism; vesicle-mediated transport; plasma membrane; 11 CPS1 proteolysis and peptidolysis; nitrogen metabolism; vacuole (sensu Fungi); 01 06 UFD2 ubiquitin-dependent protein catabolism; response to stress; 06 UBC5 protein polyubiquitination; protein monoubiquitination; endocytosis; response to stress; response to unfolded protein; sporulation (sensu Saccharomyces); proteasome complex (sensu Eukarya); 14 08 11 06 UBC4 protein polyubiquitination; protein monoubiquitination; response to stress; sporulation (sensu Saccharomyces); proteasome complex (sensu Eukarya); 14 06 11 08 YGR226C YEL073C YIL055C OKP1 chromosome segregation; condensed nuclear chromosome kinetochore; 03 SPO77 sporulation (sensu Saccharomyces); SFP1 regulation of cell size; nucleus; 03 14 MPS1 mitotic spindle checkpoint; spindle pole body duplication (sensu Saccharomyces); condensed nuclear chromosome kinetochore; spindle pole body; 03 YCL005W GPI1 GPI anchor biosynthesis; membrane; 14 01 10 COQ3 ubiquinone metabolism; ubiquinone biosynthesis; mitochondrion; mitochondrial inner membrane; extrinsic to membrane; 01 ZRG17 zinc ion transport; YOX1 negative regulation of transcription from Pol II promoter\, mitotic; regulation of mitotic cell cycle; nucleus; 04 PLB2 glycerophospholipid metabolism; extracellular; cell wall (sensu Fungi); 01 ### CLUSTER 2 ### 04 Transcription/RNA processing/RNA transport REB1 regulation of transcription from Pol II promoter; transcription termination from Pol I promoter; nucleus; 04 TOF2 DNA topological change; cell; SCT1 phospholipid biosynthesis; CLU1 translational initiation; mitochondrion organization and biogenesis; cytoplasm; eukaryotic translation initiation factor 3 complex; 05 YMR233W TOP2 regulation of mitotic recombination; DNA topological change; DNA strand elongation; chromatin assembly/disassembly; meiotic recombination; synaptonemal complex; nucleus; 03 TOF1 DNA topological change; cell; 03 YFR016C PHB2 replicative cell aging; proteolysis and peptidolysis; mitochondrion; mitochondrial inner membrane; 03 YHL010C SGS1 mitotic chromosome segregation; DNA unwinding; chromosome organization and biogenesis (sensu Eukarya); meiotic chromosome segregation; nucleolus; 14 03 ERD1 protein-ER retention; membrane; 06 YJL055W YIR036C 01 SKT5 cytokinesis; cell wall chitin biosynthesis; response to osmotic stress; contractile ring (sensu Saccharomyces); 14 01 YPC1 ceramide metabolism; endoplasmic reticulum; 01 YNR073C 01 NPT1 chromatin silencing at ribosomal DNA (rDNA); chromatin silencing at telomere; nicotinate nucleotide biosynthesis\, salvage pathway; nucleus; 01 NHA1 monovalent inorganic cation homeostasis; plasma membrane; 13 YMR118C 02 NFU1 iron ion homeostasis; mitochondrial matrix; 01 13 MAK32 virus-host interaction; CHK1 DNA damage response\, signal transduction resulting in cell cycle arrest; protein amino acid phosphorylation; nucleus; 03 SDS24 DNA metabolism; endocytosis; meiosis; cytoplasm; 06 YJR011C YDR366C YHR003C 01 DOM34 protein biosynthesis; 03 05 GFD1 mRNA-nucleus export; nuclear pore; cytoplasm; 08 TRK1 potassium ion homeostasis; plasma membrane; 13 08 COQ6 ubiquinone metabolism; mitochondrion; mitochondrial inner membrane; 01 YFR038W 03 YDR334W 04 RDH54 double-strand break repair via break-induced replication; meiotic recombination; heteroduplex formation; nucleus; 03 FUN30 chromosome organization and biogenesis (sensu Eukarya); 03 YNL019C CHD1 chromatin modeling; RNA elongation from Pol II promoter; transcription elongation factor complex; 04 ISW1 chromatin modeling; nucleus; 04 NHP10 VPS1 protein-vacuolar targeting; peroxisome organization and biogenesis; vacuolar transport; protein-Golgi retention; membrane fraction; 06 YLR247C RFX1 DNA damage response\, signal transduction resulting in cell cycle arrest; negative regulation of transcription from Pol II promoter; nucleus; cytoplasm; 04 YNG2 chromatin modification; histone acetyltransferase complex; nucleus; YJR119C 04 RSC2 chromatin modeling; nucleosome remodeling complex; 03 BDF1 sporulation (sensu Saccharomyces); nucleus; 14 04 RSC4 chromatin modeling; nucleosome remodeling complex; 03 RSC1 chromatin modeling; nucleosome remodeling complex; 03 CDA2 spore wall assembly (sensu Saccharomyces); chitosan layer of spore wall; 01 14 NHP6B establishment and/or maintenance of chromatin architecture; regulation of transcription from Pol II promoter; regulation of transcription from Pol III promoter; nuclear chromatin; 14 BDF2 nucleus; 04 DMC1 meiotic joint molecule formation; meiosis; meiotic recombination; condensed nuclear chromosome; nucleus; 03 ESA1 regulation of cell cycle; regulation of transcription from Pol II promoter; histone acetylation; histone acetyltransferase complex; 03 06 VPS20 late endosome to vacuole transport; cytoplasm; endosome; ARP4 establishment and/or maintenance of chromatin architecture; regulation of transcription\, DNA-dependent; regulation of transcription from Pol II promoter; histone acetylation; histone acetyltransferase complex; nuclear chromatin; nucleus; KRE27 VID21 TRA1 regulation of transcription from Pol II promoter; histone acetylation; histone acetyltransferase complex; 04 EPL1 regulation of transcription from Pol II promoter; histone acetylation; histone acetyltransferase complex; ARP1 mitotic anaphase B; dynactin complex; 08 14 03 YGR122W SPT6 establishment and/or maintenance of chromatin architecture; nucleosome assembly; regulation of transcription\, DNA-dependent; RNA elongation from Pol II promoter; nucleus; transcription elongation factor complex; 03 04 SPT4 establishment and/or maintenance of chromatin architecture; regulation of transcription\, DNA-dependent; RNA elongation from Pol II promoter; chromosome segregation; nucleus; transcription elongation factor complex; 03 04 HIR1 regulation of transcription from Pol II promoter; chromosome\, pericentric region; nucleus; 04 03 SNF11 chromatin modeling; nucleosome remodeling complex; SWI/SNF complex; 14 04 01 SNF6 chromatin modeling; nucleosome remodeling complex; SWI/SNF complex; 01 04 14 SNF5 chromatin modeling; nucleosome remodeling complex; SWI/SNF complex; 04 01 14 STH1 chromatin modeling; meiosis; nucleus; 04 03 RAD5 DNA repair; nuclear chromatin; 03 HIR2 regulation of transcription from Pol II promoter; nucleus; 04 03 SWI3 chromatin modeling; nucleosome remodeling complex; SWI/SNF complex; 14 04 01 RSC8 chromatin modeling; nucleus; nucleosome remodeling complex; 03 04 SUC2 sucrose catabolism; extracellular; cytoplasm; 01 RPH1 negative regulation of transcription from Pol II promoter; DNA repair; nucleus; 04 GIS1 intracellular signaling cascade; 03 MOT3 transcription; nucleus; 04 GNT1 N-linked glycosylation; Golgi medial cisterna; BIO3 biotin biosynthesis; cytoplasm; 01 INO1 myo-inositol metabolism; 01 SCS2 myo-inositol metabolism; protein-ER targeting; endoplasmic reticulum; integral to membrane; 01 04 INO2 phospholipid biosynthesis; positive regulation of transcription from Pol II promoter; nucleus; 01 04 CHO2 phosphatidylcholine biosynthesis; endoplasmic reticulum; 01 CHO1 phosphatidylserine biosynthesis; endoplasmic reticulum; 01 OPI1 negative regulation of transcription from Pol II promoter; phospholipid biosynthesis; nucleus; 01 04 TYS1 amino acid activation; tyrosyl-tRNA aminoacylation; nucleus; cytoplasm; 05 BCK2 regulation of cell cycle; G1/S transition of mitotic cell cycle; YLR422W RTG3 transcription initiation from Pol II promoter; nucleus; cytoplasm; 01 04 YNR064C RTG1 transcription initiation from Pol II promoter; protein localization; nucleus; cytoplasm; 01 04 RTG2 intracellular signaling cascade; cytoplasm; 01 SIN3 chromatin silencing at ribosomal DNA (rDNA); chromatin silencing at HML and HMR (sensu Saccharomyces); chromatin silencing at telomere; regulation of transcription from Pol II promoter; histone deacetylase complex; 01 14 04 RPD3 chromatin silencing at ribosomal DNA (rDNA); loss of chromatin silencing during replicative cell aging; mitotic recombination; establishment and/or maintenance of chromatin architecture; chromatin silencing; chromatin silencing at HML and HMR (sensu Saccharomyces); chromatin silencing at telomere; regulation of transcription\, DNA-dependent; protein amino acid deacetylation; histone deacetylase complex; 01 04 14 03 ECM16 ribosome biogenesis; processing of 20S pre-rRNA; nucleolus; small nucleolar ribonucleoprotein complex; STB1 G1/S transition of mitotic cell cycle; nucleus; 04 PHO23 chromatin modification; histone deacetylase complex; nucleus; 04 ABF2 mitochondrion inheritance; mitochondrial genome maintenance; mitochondrial chromosome; 03 TRK2 potassium ion homeostasis; plasma membrane; 08 RXT2 conjugation with cellular fusion; invasive growth; RCO1 SAP30 chromatin silencing at ribosomal DNA (rDNA); chromatin silencing at HML and HMR (sensu Saccharomyces); chromatin silencing at telomere; histone deacetylase complex; 14 04 STB2 histone deacetylation; nucleus; Sin3 complex; 04 SDS3 transcriptional gene silencing; histone deacetylation; histone deacetylase complex; 14 04 STB4 nucleus; 04 STB3 04 STB6 04 STB5 response to xenobiotic stimulus; nucleus; 04 IOC3 chromatin modeling; nucleus; HDA1 loss of chromatin silencing during replicative cell aging; establishment and/or maintenance of chromatin architecture; regulation of transcription\, DNA-dependent; protein amino acid deacetylation; histone deacetylase complex; 03 04 06 MAM33 aerobic respiration; mitochondrial matrix; PFK1 glycolysis; cytoplasm; 6-phosphofructokinase complex; 01 02 IME4 meiosis; mRNA modification; 04 14 UME6 negative regulation of transcription\, mitotic; entry into meiosis; nucleus; 01 04 03 IME2 protein amino acid phosphorylation; regulation of meiosis; nucleus; 03 14 RME1 negative regulation of transcription from Pol II promoter; meiosis; nucleus; 03 04 IDS2 meiosis; 14 10 03 RIM15 protein amino acid phosphorylation; response to stress; regulation of meiosis; 06 04 PMD1 sporulation; 14 YVH1 meiosis; sporulation (sensu Saccharomyces); 14 03 13 IME1 meiosis; nucleus; 14 04 03 ARG80 arginine metabolism; positive regulation of transcription from Pol II promoter; nucleus; 01 04 HMRA2 14 HMLALPHA2 regulation of transcription from Pol II promoter; regulation of transcription\, mating-type specific; donor preference; nucleus; 14 ARG82 arginine metabolism; phosphorylation; nucleus; 01 14 04 ARG81 arginine metabolism; negative regulation of calcium ion dependent exocytosis; nucleus; 01 04 LYS7 intracellular copper ion transport; cytosol; 11 06 13 SIP2 protein amino acid phosphorylation; signal transduction; cell aging; filamentous growth; cytoplasm; plasma membrane; 04 MIF2 mitotic spindle assembly (sensu Saccharomyces); condensed nuclear chromosome kinetochore; nucleus; 03 CBF2 chromosome segregation; condensed nuclear chromosome kinetochore; 03 NFI1 chromosome condensation; 03 14 YLR050C VAC17 vacuole inheritance; vacuolar membrane; SWC1 ### CLUSTER 3 ### 04 Transcription/RNA processing/RNA transport PHO3 thiamin transport; periplasmic space (sensu Fungi); 01 PHO11 phosphate metabolism; extracellular; 01 YCR082W MED7 transcription from Pol II promoter; mediator complex; 04 YBR255W YDR267C FIR1 mRNA polyadenylation; 04 OSH3 steroid biosynthesis; cytoplasm; 01 ECM32 regulation of translational termination; polysome; 03 SPC34 mitotic spindle assembly (sensu Saccharomyces); microtubule nucleation; condensed nuclear chromosome kinetochore; spindle pole body; spindle; 03 ASK1 mitotic spindle assembly (sensu Saccharomyces); condensed nuclear chromosome kinetochore; condensed nuclear chromosome\, pericentric region; spindle; 03 SLI15 protein amino acid phosphorylation; chromosome segregation; kinetochore microtubule; spindle microtubule; 03 DUO1 mitotic spindle assembly (sensu Saccharomyces); condensed nuclear chromosome kinetochore; spindle; 03 YGL036W DEP1 regulation of transcription from Pol II promoter; phospholipid metabolism; 01 DAD1 mitotic spindle assembly (sensu Saccharomyces); condensed nuclear chromosome kinetochore; spindle; 03 DLD2 mitochondrial matrix; 02 TUB2 nuclear migration (sensu Saccharomyces); mitotic chromosome segregation; nuclear migration during conjugation with cellular fusion; homologous chromosome segregation; spindle pole body; polar microtubule; kinetochore microtubule; nuclear microtubule; cytoplasmic microtubule; 03 PAC2 post-chaperonin tubulin folding pathway; alpha-tubulin folding; 03 BIM1 nuclear migration (sensu Saccharomyces); microtubule depolymerization; microtubule nucleation; microtubule stabilization; mitotic spindle checkpoint; spindle pole body; cytoplasmic microtubule; 03 YJL217W VAC8 vacuole inheritance; protein-vacuolar targeting; microautophagy; homotypic vacuole fusion (non-autophagic); vacuole (sensu Fungi); 06 APG1 06 08 14 PAC11 microtubule-based process; cell; 03 14 08 DID4 protein-Golgi retention; late endosome to vacuole transport; cytoplasm; endosome; 06 08 TID3 microtubule nucleation; chromosome segregation; condensed nuclear chromosome kinetochore; condensed nuclear chromosome\, pericentric region; 03 YIL083C coenzyme A biosynthesis; intracellular; YGR052W mitochondrion; NSE1 DNA repair; cell proliferation; nucleus; YHR033W cytoplasm; 01 YCR079W SRV2 cytoskeleton organization and biogenesis; RAS protein signal transduction; actin cortical patch (sensu Saccharomyces); 10 14 COT1 cobalt ion transport; zinc ion transport; zinc ion homeostasis; vacuole (sensu Fungi); 08 13 CAX4 N-linked glycosylation; lipid biosynthesis; integral to endoplasmic reticulum membrane; 06 GCN1 regulation of translational elongation; cytosol; cytosolic ribosome (sensu Eukarya); 05 TPM1 mitochondrion inheritance; vacuole inheritance; establishment of cell polarity (sensu Saccharomyces); exocytosis; actin filament organization; apical bud growth; isotropic bud growth; actin polymerization and/or depolymerization; mRNA localization\, intracellular; vesicle-mediated transport; actin cable assembly; actin cable (sensu Saccharomyces); contractile ring (sensu Saccharomyces); 14 08 YPT11 mitochondrion inheritance; incipient bud site; bud tip; bud neck; 08 SMY1 exocytosis; bud tip; bud neck; 14 08 UBP15 protein deubiquitination; cytoplasm; 06 MYO1 cytokinesis; response to osmotic stress; axial budding; contractile ring (sensu Saccharomyces); 03 14 08 CTR9 transcription from Pol II promoter; RNA elongation from Pol II promoter; chromosome segregation; nucleus; transcription elongation factor complex; Cdc73/Paf1 complex; 03 SAM1 methionine metabolism; cytoplasm; 01 JNM1 mitotic anaphase B; dynactin complex; 03 08 NUP1 RNA-nucleus export; mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; protein-nucleus import; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear membrane organization and biogenesis; nuclear pore organization and biogenesis; nuclear pore; 08 MSO1 nonselective vesicle docking; sporulation (sensu Saccharomyces); microsome; 08 YIF1 ER to Golgi transport; COPII-coated vesicle; 08 POL1 DNA repair synthesis; DNA replication\, priming; DNA replication initiation; lagging strand elongation; alpha DNA polymerase\:primase complex; 03 MYO2 mitochondrion inheritance; vacuole inheritance; establishment of cell polarity (sensu Saccharomyces); endocytosis; apical bud growth; isotropic bud growth; vesicle-mediated transport; actin cable (sensu Saccharomyces); actin cap (sensu Saccharomyces); 08 14 RUD3 ER to Golgi transport; Golgi apparatus; 08 APG17 06 14 YNL136W ULP1 G2/M transition of mitotic cell cycle; protein desumoylation; nuclear membrane; nuclear pore; 06 YPL260W GYP5 vesicle-mediated transport; soluble fraction; cytosol; VTA1 late endosome to vacuole transport; SLK19 mitotic spindle assembly (sensu Saccharomyces); meiosis; condensed nuclear chromosome kinetochore; spindle; 03 DNF3 intracellular protein transport; trans-Golgi network transport vesicle; IWS1 RNA elongation from Pol II promoter; transcription elongation factor complex; BBP1 microtubule nucleation; spindle pole body; 14 03 ARF3 intracellular protein transport; 08 06 TFP3 vacuolar acidification; hydrogen-transporting ATPase V0 domain; 13 08 06 NIP100 mitotic anaphase B; dynactin complex; 08 14 03 KIP2 nuclear migration (sensu Saccharomyces); mitotic anaphase B; microtubule stabilization; kinesin complex; cytoplasmic microtubule; 03 08 VIK1 microtubule-based process; spindle pole body; kinesin complex; STU1 microtubule nucleation; spindle pole body; CIN4 microtubule-based process; 03 SRT1 protein amino acid glycosylation; lipid particle; 06 DYN1 mitotic spindle elongation; nuclear migration (sensu Saccharomyces); mitotic chromosome segregation; mitotic spindle orientation; spindle pole body; cytoplasmic microtubule; 08 03 MLP1 protein-nucleus import; nuclear membrane; nucleoplasm; 03 IMH1 vesicle-mediated transport; cytosol; 06 08 BRO1 ubiquitin-dependent protein catabolism; vacuolar transport; signal transduction; cytoplasm; endosome; 13 11 ARP5 protein-vacuolar targeting; nucleus; KEL2 conjugation with cellular fusion; bud tip; bud neck; shmoo tip; 14 13 BRE1 chromatin silencing at telomere; protein monoubiquitination; histone methylation; histone ubiquitination; nucleus; CNM67 microtubule nucleation; spindle pole body; outer plaque of spindle pole body; 03 14 ADY3 protein complex assembly; spore wall assembly (sensu Saccharomyces); sporulation; prospore membrane; spindle; YLL032C YLR431C STU2 mitotic spindle assembly (sensu Saccharomyces); microtubule nucleation; spindle pole body; BIK1 mitotic anaphase B; mitotic spindle assembly; spindle pole body; spindle microtubule; 14 03 SHE9 mitochondrion organization and biogenesis; inner mitochondrial membrane organization and biogenesis; mitochondrial inner membrane; CIN8 mitotic chromosome segregation; mitotic spindle assembly (sensu Saccharomyces); mitotic anaphase B; kinesin complex; spindle microtubule; 03 08 YMR031C SNX4 transport; autophagy; membrane; 06 CIK1 mitotic chromosome segregation; mitotic spindle assembly (sensu Saccharomyces); mitotic spindle orientation; meiosis; spindle pole body; spindle; kinesin complex; cytoplasmic microtubule; 08 03 SMC5 DNA repair; cell proliferation; nucleus; 03 TOP1 regulation of mitotic recombination; DNA topological change; DNA strand elongation; chromatin assembly/disassembly; regulation of transcription from Pol II promoter; RNA elongation from Pol II promoter; mitotic chromosome condensation; nuclear migration; nucleus; 03 04 SPO21 meiosis; spore wall assembly (sensu Saccharomyces); spindle pole body; 03 MPC54 spore wall assembly (sensu Saccharomyces); spindle pole body; 03 YLR254C KIP1 mitotic anaphase B; microtubule nucleation; spindle pole body; kinesin complex; spindle microtubule; 03 08 COY1 Golgi vesicle transport; Golgi membrane; 03 YML119W YGR130C cytoplasm; KEL1 cytogamy; cellular morphogenesis; regulation of cell shape; plasma membrane fusion; cytoplasm; bud tip; bud neck; shmoo tip; 14 13 PLO2 YDR532C TPM2 mitochondrion inheritance; vacuole inheritance; establishment of cell polarity (sensu Saccharomyces); exocytosis; actin filament organization; apical bud growth; isotropic bud growth; actin polymerization and/or depolymerization; mRNA localization\, intracellular; vesicle-mediated transport; actin cable assembly; actin cable (sensu Saccharomyces); contractile ring (sensu Saccharomyces); 14 NUM1 nuclear migration (sensu Saccharomyces); microtubule cytoskeleton organization and biogenesis; bud tip; cell cortex; 03 TAF11 G1-specific transcription in mitotic cell cycle; transcription initiation from Pol II promoter; transcription factor TFIID complex; 04 TAF1 G1-specific transcription in mitotic cell cycle; transcription initiation from Pol II promoter; protein amino acid phosphorylation; transcription factor TFIID complex; 03 04 SAS3 chromatin silencing at HML and HMR (sensu Saccharomyces); chromatin silencing at telomere; chromatin modification; nuclear nucleosome; 04 14 SNF2 chromatin modeling; nucleosome remodeling complex; SWI/SNF complex; 01 04 14 TAF3 G1-specific transcription in mitotic cell cycle; transcription initiation from Pol II promoter; transcription factor TFIID complex; 04 TFG2 transcription initiation from Pol II promoter; transcription factor TFIIF complex; 04 TFG1 transcription initiation from Pol II promoter; transcription factor TFIIF complex; 04 MGM1 mitochondrial genome maintenance; mitochondrion organization and biogenesis; mitochondrial fusion; mitochondrial intermembrane space; TAF10 G1-specific transcription in mitotic cell cycle; establishment and/or maintenance of chromatin architecture; transcription initiation from Pol II promoter; protein amino acid acetylation; chromatin modification; histone acetylation; SAGA complex; transcription factor TFIID complex; 04 RTF1 transcription from Pol II promoter; RNA elongation from Pol II promoter; transcription elongation factor complex; Cdc73/Paf1 complex; 04 PAF1 RNA elongation from Pol II promoter; transcription elongation factor complex; 04 CDC73 RNA elongation from Pol II promoter; transcription elongation factor complex; 04 SPT5 establishment and/or maintenance of chromatin architecture; regulation of transcription\, DNA-dependent; RNA elongation from Pol II promoter; nucleus; transcription elongation factor complex; 04 03 HOT1 regulation of transcription from Pol II promoter; hyperosmotic response; nuclear chromosome; SCW4 conjugation with cellular fusion; cell wall (sensu Fungi); RLI1 RIC1 intracellular protein transport; nucleus; Golgi apparatus; 04 RPG1 translational initiation; incipient bud site; cytoplasm; ribosome; eukaryotic translation initiation factor 3 complex; 05 03 HCR1 protein biosynthesis; eukaryotic translation initiation factor 3 complex; 04 TFC7 transcription initiation from Pol III promoter; transcription factor TFIIIC complex; 01 04 GAL4 galactose metabolism; regulation of transcription\, DNA-dependent; nucleus; 01 04 YAH1 heme a biosynthesis; mitochondrial matrix; SNF8 protein-vacuolar targeting; negative regulation of transcription by glucose; endosome; 01 YCR051W TIF34 translational initiation; eukaryotic translation initiation factor 3 complex; 05 NIP1 translational initiation; cytoplasm; eukaryotic translation initiation factor 3 complex; 05 TIF35 translational initiation; eukaryotic translation initiation factor 3 complex; 05 TFC4 transcription initiation from Pol III promoter; transcription factor TFIIIC complex; 04 TFC1 transcription initiation from Pol III promoter; transcription factor TFIIIC complex; 04 TOA1 transcription initiation from Pol II promoter; transcription factor TFIIA complex; 04 PRT1 translational initiation; cytoplasm; eukaryotic translation initiation factor 3 complex; 05 03 14 TOA2 transcription initiation from Pol II promoter; transcription factor TFIIA complex; 04 IST2 response to osmotic stress; GLT1 glutamate biosynthesis; cell; 01 YOR262W VPS36 protein-vacuolar targeting; negative regulation of transcription by glucose; protein-Golgi retention; endosome; 06 SNF7 late endosome to vacuole transport; cytoplasm; endosome; 14 06 01 08 RLM1 cell wall organization and biogenesis; signal transduction; positive regulation of transcription from Pol II promoter; nucleus; 04 14 YER184C 04 MAL13 carbohydrate metabolism; regulation of transcription\, DNA-dependent; nucleus; 01 04 MSS1 protein biosynthesis; mitochondrial inner membrane; 04 05 HAP4 regulation of carbohydrate metabolism; transcription; CCAAT-binding factor complex; 04 GAL11 transcription from Pol II promoter; mediator complex; 14 04 01 APL1 vesicle-mediated transport; AP-2 adaptor complex; 08 06 MHR1 mitochondrial genome maintenance; nucleus; mitochondrion; 03 GAL80 galactose metabolism; regulation of transcription\, DNA-dependent; nucleus; cytoplasm; 01 04 HAP5 regulation of carbohydrate metabolism; transcription; CCAAT-binding factor complex; 04 PPR1 regulation of transcription\, DNA-dependent; uracil biosynthesis; nucleus; 01 04 HIS3 histidine biosynthesis; cell; 01 SRB2 transcription from Pol II promoter; mediator complex; 04 RPT4 ubiquitin-dependent protein catabolism; nucleus; proteasome regulatory particle (sensu Eukarya); proteasome regulatory particle\, base subcomplex (sensu Eukarya); 04 06 GAL3 galactose metabolism; regulation of transcription\, DNA-dependent; cytoplasm; 04 01 GAL1 galactose metabolism; 01 04 HAP1 aerobic respiration; positive regulation of transcription from Pol II promoter; nucleus; 04 GAL7 galactose metabolism; cytoplasm; 01 GAL10 galactose metabolism; 01 SRB8 negative regulation of transcription from Pol II promoter; transcription factor complex; 04 01 RGR1 transcription from Pol II promoter; mediator complex; 01 14 04 02 PGD1 transcription from Pol II promoter; mediator complex; 03 04 MED6 transcription from Pol II promoter; mediator complex; 04 MED2 transcription from Pol II promoter; mediator complex; 04 ROX3 transcription from Pol II promoter; mediator complex; nucleus; 04 11 MKS1 regulation of nitrogen utilization; intracellular; 01 04 SRB6 transcription from Pol II promoter; mediator complex; 01 14 04 SRB5 transcription from Pol II promoter; mediator complex; 04 SRB4 transcription from Pol II promoter; mediator complex; 04 SRB7 transcription from Pol II promoter; mediator complex; 04 TFA2 transcription initiation from Pol II promoter; transcription factor TFIIE complex; 04 TFA1 transcription initiation from Pol II promoter; transcription factor TFIIE complex; 04 MED8 transcription from Pol II promoter; mediator complex; 04 YAP7 positive regulation of transcription from Pol II promoter; nucleus; 04 SIN4 transcription from Pol II promoter; mediator complex; 14 01 04 SSN8 negative regulation of transcription from Pol II promoter; meiosis; transcription factor complex; 03 04 01 GCN4 regulation of transcription from Pol II promoter; amino acid biosynthesis; nucleus; 01 04 TAF6 G1-specific transcription in mitotic cell cycle; establishment and/or maintenance of chromatin architecture; transcription initiation from Pol II promoter; protein amino acid acetylation; chromatin modification; histone acetylation; SAGA complex; transcription factor TFIID complex; 04 TAF12 G1-specific transcription in mitotic cell cycle; establishment and/or maintenance of chromatin architecture; transcription initiation from Pol II promoter; protein amino acid acetylation; chromatin modification; histone acetylation; SAGA complex; transcription factor TFIID complex; 04 NGG1 chromatin modification; histone acetylation; SAGA complex; 01 04 ADA2 chromatin modification; histone acetylation; SAGA complex; 04 ADR1 regulation of carbohydrate metabolism; transcription; peroxisome organization and biogenesis; nucleus; 04 01 SPT7 conjugation with cellular fusion; protein complex assembly; chromatin modification; histone acetylation; SAGA complex; 04 SPT3 conjugation with cellular fusion; pseudohyphal growth; invasive growth; chromatin modification; histone acetylation; sporulation (sensu Fungi); SAGA complex; 14 04 TAF2 G1-specific transcription in mitotic cell cycle; transcription initiation from Pol II promoter; transcription factor TFIID complex; 04 SPT20 chromatin modification; histone acetylation; SAGA complex; 04 GCN5 chromatin modification; histone acetylation; SAGA complex; 04 03 06 SPT8 chromatin modification; histone acetylation; SAGA complex; nucleus; 04 RRI1 protein deneddylation; adaptation to pheromone during conjugation with cellular fusion; signalosome complex; POP1 rRNA processing; tRNA processing; ribonuclease MRP complex; nucleolar ribonuclease P complex; 04 CSI1 protein deneddylation; adaptation to pheromone during conjugation with cellular fusion; signalosome complex; CBT1 mRNA processing; cytochrome biogenesis; 04 SAP190 G1/S transition of mitotic cell cycle; cytoplasm; 03 14 YCK3 protein amino acid phosphorylation; nucleus; plasma membrane; 03 PFS1 spore wall assembly (sensu Fungi); 14 YCK2 cellular morphogenesis; cytokinesis; protein amino acid phosphorylation; endocytosis; plasma membrane; bud neck; 14 11 03 08 TGL1 lipid metabolism; lipid particle; 01 CAF40 regulation of transcription from Pol II promoter; CCR4-NOT complex; RIO2 processing of 20S pre-rRNA; nucleus; cytosol; TOM1 protein polyubiquitination; protein monoubiquitination; nucleocytoplasmic transport; nuclear organization and biogenesis; mitosis; 03 SSN2 negative regulation of transcription from Pol II promoter; transcription factor complex; 04 01 DBF2 nuclear division; protein amino acid phosphorylation; spindle pole body; bud neck; 03 04 YAK1 protein amino acid phosphorylation; cell growth and/or maintenance; nucleus; cytoplasm; 03 DHH1 mRNA catabolism\, nonsense-mediated; deadenylation-dependent decapping; cytoplasmic mRNA processing body; cytoplasm; 04 CDC39 regulation of cell cycle; negative regulation of transcription from Pol II promoter; mRNA catabolism\, deadenylation-dependent; poly(A) tail shortening; response to pheromone during conjugation with cellular fusion; regulation of transcription from Pol II promoter; nucleus; cytoplasm; CCR4-NOT core complex; 14 04 CCR4 mRNA catabolism\, deadenylation-dependent; poly(A) tail shortening; regulation of transcription from Pol II promoter; cytoplasm; CCR4-NOT core complex; 01 04 CDC36 regulation of cell cycle; negative regulation of transcription from Pol II promoter; mRNA catabolism\, deadenylation-dependent; poly(A) tail shortening; response to pheromone during conjugation with cellular fusion; regulation of transcription from Pol II promoter; nucleus; cytoplasm; CCR4-NOT core complex; 03 04 CAF130 regulation of transcription from Pol II promoter; CCR4-NOT complex; NOT3 poly(A) tail shortening; regulation of transcription from Pol II promoter; cytoplasm; CCR4-NOT core complex; 04 MOT2 poly(A) tail shortening; conjugation with cellular fusion; regulation of transcription from Pol II promoter; cytoplasm; CCR4-NOT core complex; 14 04 YMR247C YMR115W RAT1 35S primary transcript processing; RNA processing; nucleus; 04 08 STP22 protein-membrane targeting; protein-vacuolar targeting; endosome; 06 08 PTC4 PTC3 regulation of CDK activity; inactivation of MAPK (osmolarity sensing); protein amino acid dephosphorylation; RNH202 YLR446W SWI1 chromatin modeling; nucleosome remodeling complex; SWI/SNF complex; 01 14 04 NUD1 microtubule nucleation; spindle pole body; 03 YAP5 positive regulation of transcription from Pol II promoter; nucleus; 04 ADP1 transport; cytoplasm; endoplasmic reticulum; integral to membrane; EAP1 negative regulation of translation; mRNA cap complex; 05 CTL1 RNA processing; nucleus; cytoplasm; 04 YCK1 cellular morphogenesis; cytokinesis; protein amino acid phosphorylation; endocytosis; endoplasmic reticulum; plasma membrane; 11 14 08 03 RPN2 ubiquitin-dependent protein catabolism; proteasome regulatory particle (sensu Eukarya); 06 04 ADE16 'de novo' IMP biosynthesis; sporulation (sensu Saccharomyces); aerobic respiration; cytosol; 01 YML053C DSK2 spindle pole body duplication (sensu Saccharomyces); nucleus; 03 NAS2 ubiquitin-dependent protein catabolism; cytoplasm; 14 ENT3 actin cortical patch assembly; Golgi to endosome transport; endocytosis; actin filament organization; actin cortical patch (sensu Saccharomyces); clathrin vesicle coat; YNL026W TWF1 polar budding; actin polymerization and/or depolymerization; actin cortical patch (sensu Saccharomyces); 14 MRS3 transport; RNA splicing; mitochondrion; 08 04 CWP2 regulation of pH; cell wall organization and biogenesis; cell wall (sensu Fungi); TTR1 response to oxidative stress; regulation of redox homeostasis; mitochondrion; cytosol; 01 11 TRX2 vacuole inheritance; DNA dependent DNA replication; response to oxidative stress; regulation of redox homeostasis; vacuole fusion (non-autophagic); vacuole (sensu Fungi); cytosol; 03 06 11 YML131W 01 YIM1 mitochondrial processing; cytoplasm; mitochondrial inner membrane; lipid particle; 06 YNL134C AME1 spindle pole body; 03 CAP1 endocytosis; response to osmotic stress; actin filament organization; cell wall organization and biogenesis; actin cortical patch (sensu Saccharomyces); F-actin capping protein complex; 14 TPD3 protein biosynthesis; protein amino acid dephosphorylation; actin filament organization; mitotic spindle checkpoint; bud growth; protein phosphatase type 2A complex; nucleus; cytoplasm; spindle pole body; bud tip; bud neck; shmoo tip; 14 04 03 PPH21 G1/S transition of mitotic cell cycle; protein biosynthesis; protein amino acid dephosphorylation; actin filament organization; mitotic spindle checkpoint; bud growth; protein phosphatase type 2A complex; 01 14 03 PPH22 G1/S transition of mitotic cell cycle; protein biosynthesis; protein amino acid dephosphorylation; actin filament organization; mitotic spindle checkpoint; bud growth; protein phosphatase type 2A complex; 01 14 03 YFL006W YNL311C ubiquitin-dependent protein catabolism; ubiquitin ligase complex; THI20 thiamin biosynthesis; 04 AAD15 aldehyde metabolism; 01 02 REX3 RNA processing; 01 CYC2 mitochondrial membrane organization and biogenesis; mitochondrial intermembrane space protein import; mitochondrion; 08 NAS6 proteolysis and peptidolysis; proteasome regulatory particle (sensu Eukarya); 06 UBP5 protein deubiquitination; cytoplasm; 06 PRE3 ubiquitin-dependent protein catabolism; response to stress; sporulation (sensu Saccharomyces); proteasome core complex (sensu Eukarya); proteasome core complex\, beta-subunit complex (sensu Eukarya); 06 14 11 PUP3 ubiquitin-dependent protein catabolism; proteasome core complex (sensu Eukarya); proteasome core complex\, beta-subunit complex (sensu Eukarya); 06 PRE4 ubiquitin-dependent protein catabolism; proteasome core complex (sensu Eukarya); proteasome core complex\, beta-subunit complex (sensu Eukarya); 06 UMP1 protein catabolism; proteasome core complex (sensu Eukarya); 06 YMR148W integral to membrane; YMR099C PRE8 ubiquitin-dependent protein catabolism; proteasome core complex (sensu Eukarya); 06 PRE7 ubiquitin-dependent protein catabolism; proteasome core complex (sensu Eukarya); 06 MVP1 protein-vacuolar targeting; cytoplasm; 06 08 RPT1 ubiquitin-dependent protein catabolism; proteasome regulatory particle (sensu Eukarya); 06 03 YLR387C 06 SGT2 RPN13 proteolysis and peptidolysis; proteasome regulatory particle (sensu Eukarya); PRE6 ubiquitin-dependent protein catabolism; proteasome core complex (sensu Eukarya); proteasome core complex\, alpha-subunit complex (sensu Eukarya); 06 YOR131C SGT1 centromere/kinetochore complex maturation; regulation of cell cycle; protein complex assembly; protein ubiquitination; cAMP-mediated signaling; ubiquitin ligase complex; 06 03 10 UBP2 protein deubiquitination; cytoplasm; 06 RPN8 ubiquitin-dependent protein catabolism; proteasome regulatory particle (sensu Eukarya); proteasome regulatory particle\, lid subcomplex (sensu Eukarya); 06 RET3 retrograde (Golgi to ER) transport; COPI vesicle coat; 08 YPT52 protein-vacuolar targeting; endocytosis; late endosome; 08 06 UBC1 protein polyubiquitination; protein monoubiquitination; endocytosis; germination (sensu Saccharomyces); proteasome complex (sensu Eukarya); 14 06 08 BET4 protein amino acid geranylgeranylation; Rab-protein geranylgeranyltransferase complex; 01 06 IST1 YIR024C 03 PRE9 ubiquitin-dependent protein catabolism; proteasome core complex (sensu Eukarya); 06 YOL107W ECM29 cell wall organization and biogenesis; GLC8 glycogen biosynthesis; cytoplasm; 01 YFR011C RTT103 negative regulation of DNA transposition; RPT6 ubiquitin-dependent protein catabolism; nucleus; proteasome regulatory particle (sensu Eukarya); proteasome regulatory particle\, base subcomplex (sensu Eukarya); 03 06 UBC13 protein polyubiquitination; postreplication repair; protein monoubiquitination; nucleus; cytoplasm; 06 RPN3 ubiquitin-dependent protein catabolism; proteasome regulatory particle (sensu Eukarya); 06 UBP6 protein deubiquitination; proteasome regulatory particle (sensu Eukarya); 06 RPN11 ubiquitin-dependent protein catabolism; proteasome regulatory particle\, lid subcomplex (sensu Eukarya); 06 RPN5 ubiquitin-dependent protein catabolism; proteasome regulatory particle (sensu Eukarya); proteasome regulatory particle\, lid subcomplex (sensu Eukarya); 06 RPT2 ubiquitin-dependent protein catabolism; proteasome regulatory particle (sensu Eukarya); 06 RPN6 ubiquitin-dependent protein catabolism; proteasome regulatory particle (sensu Eukarya); 06 RPT3 ubiquitin-dependent protein catabolism; proteasome regulatory particle (sensu Eukarya); proteasome regulatory particle\, base subcomplex (sensu Eukarya); 06 RPN9 ubiquitin-dependent protein catabolism; proteasome regulatory particle (sensu Eukarya); proteasome regulatory particle\, lid subcomplex (sensu Eukarya); 06 RPN12 ubiquitin-dependent protein catabolism; proteasome regulatory particle (sensu Eukarya); 03 06 11 SCL1 ubiquitin-dependent protein catabolism; proteasome core complex\, alpha-subunit complex (sensu Eukarya); 06 PRE1 ubiquitin-dependent protein catabolism; response to stress; sporulation (sensu Saccharomyces); nucleus; proteasome core complex (sensu Eukarya); proteasome core complex\, beta-subunit complex (sensu Eukarya); 06 11 14 RPN10 ubiquitin-dependent protein catabolism; proteasome regulatory particle (sensu Eukarya); 06 PIL1 PUP1 ubiquitin-dependent protein catabolism; proteasome core complex (sensu Eukarya); proteasome core complex\, beta-subunit complex (sensu Eukarya); 06 PRE5 ubiquitin-dependent protein catabolism; proteasome core complex (sensu Eukarya); proteasome core complex\, alpha-subunit complex (sensu Eukarya); 06 RPT5 ubiquitin-dependent protein catabolism; proteasome regulatory particle (sensu Eukarya); proteasome regulatory particle\, base subcomplex (sensu Eukarya); 06 SCD6 08 NOT5 poly(A) tail shortening; regulation of transcription from Pol II promoter; cytoplasm; CCR4-NOT core complex; 04 YOP1 membrane organization and biogenesis; membrane; 08 AGC1 transport; mitochondrial inner membrane; 08 01 SNU66 nuclear mRNA splicing\, via spliceosome; small nuclear ribonucleoprotein complex; 04 HUT1 UDP-galactose transport; RPN7 ubiquitin-dependent protein catabolism; proteasome regulatory particle (sensu Eukarya); 06 NTO1 04 YPL247C YNL095C integral to membrane; CTI6 positive regulation of transcription; nucleus; EPS1 protein-ER retention; endoplasmic reticulum membrane; 06 FCP1 transcription; protein amino acid dephosphorylation; nucleus; 04 SSO1 Golgi to plasma membrane transport; nonselective vesicle fusion; integral to plasma membrane; 08 14 SOG2 CBC2 nuclear mRNA splicing\, via spliceosome; commitment complex; snRNA cap binding complex; 03 04 PUF2 mRNA catabolism\, deadenylation-dependent; ZIP2 synaptonemal complex formation; synaptonemal complex; 03 PSR2 response to stress; plasma membrane; 06 SKY1 mRNA splice site selection; cell ion homeostasis; positive regulation of protein-nucleus import; response to drug; cytoplasm; RLR1 DNA recombination; RNA elongation from Pol II promoter; mRNA-nucleus export; THO complex; 05 04 VPS24 late endosome to vacuole transport; cytoplasm; endosome; 06 08 PGU1 pseudohyphal growth; pectin catabolism; extracellular; 01 MAM1 meiotic chromosome segregation; condensed nuclear chromosome kinetochore; SOM1 proteolysis and peptidolysis; mitochondrial inner membrane; mitochondrial inner membrane peptidase complex; 06 08 YCR102C AAD10 aldehyde metabolism; 02 01 AAD6 aldehyde metabolism; 01 02 AAD3 aldehyde metabolism; 01 02 SNL1 nuclear pore organization and biogenesis; nuclear membrane; endoplasmic reticulum membrane; membrane; DCG1 nitrogen metabolism; 01 MGM101 mitochondrial genome maintenance; DNA repair; mitochondrial chromosome; 03 CBK1 response to pheromone during conjugation with cellular fusion; cellular morphogenesis during conjugation with cellular fusion; regulation of exit from mitosis; establishment and/or maintenance of cell polarity (sensu Saccharomyces); nucleus; cytoplasm; bud; bud neck; NBP35 nucleus; RNH70 DNA replication; RNA processing; nucleus; 01 HRT3 YOL111C cytoplasm; 06 AAD14 aldehyde metabolism; 01 02 CPR5 cytoplasm; endoplasmic reticulum; 06 YFR012W BNS1 meiosis; 03 YDR541C 01 YDR476C YBR204C lipid particle; 01 ECM12 cell wall organization and biogenesis; SNO1 pyridoxine metabolism; thiamin biosynthesis; 11 SNZ2 pyridoxine metabolism; thiamin biosynthesis; 01 11 OYE2 02 SNZ3 pyridoxine metabolism; thiamin biosynthesis; 11 SNO3 pyridoxine metabolism; thiamin biosynthesis; 11 YMR258C YLR460C PER1 response to unfolded protein; manganese ion homeostasis; vacuolar membrane (sensu Fungi); 13 KIP3 nuclear migration (sensu Saccharomyces); mitotic spindle assembly (sensu Saccharomyces); mitotic spindle orientation; microtubule depolymerization; kinesin complex; nuclear microtubule; cytoplasmic microtubule; 03 08 RMD7 cell wall organization and biogenesis; YLR224W ubiquitin-dependent protein catabolism; ubiquitin ligase complex; AHT1 PPX1 polyphosphate metabolism; cytoplasm; 01 ### CLUSTER 4 ### 05 Protein synthesis YDL033C YDL036C 01 CRD1 mitochondrial membrane organization and biogenesis; lipid biosynthesis; mitochondrial membrane; 01 MRPS9 protein biosynthesis; mitochondrial small ribosomal subunit; 05 FMT1 translational initiation; methionyl-tRNA aminoacylation; mitochondrion; 04 MRPS28 ribosomal small subunit assembly and maintenance; protein biosynthesis; mitochondrial small ribosomal subunit; 05 RSM23 protein biosynthesis; mitochondrial small ribosomal subunit; 05 EHD3 fatty acid beta-oxidation; endocytosis; RSM10 protein biosynthesis; mitochondrial small ribosomal subunit; 05 MRPS5 protein biosynthesis; mitochondrial ribosome; mitochondrial small ribosomal subunit; 05 YBR219C GIM4 tubulin folding; cytoplasm; 06 USA1 PEX13 protein-peroxisome targeting; peroxisome organization and biogenesis; peroxisomal membrane; 06 08 PEX5 protein-peroxisome targeting; peroxisome organization and biogenesis; peroxisome; cytosol; 06 08 PEX14 protein-peroxisome targeting; peroxisomal membrane; 06 08 PEX2 peroxisome organization and biogenesis; peroxisomal membrane; 08 PEX1 peroxisome organization and biogenesis; 06 PEX17 peroxisome organization and biogenesis; peroxisomal membrane; 08 PEX7 protein-peroxisome targeting; peroxisome organization and biogenesis; peroxisomal matrix; cytosol; 06 08 PEX21 protein-peroxisome targeting; peroxisome; cytosol; 06 08 TUB4 mitotic spindle assembly (sensu Saccharomyces); microtubule nucleation; inner plaque of spindle pole body; outer plaque of spindle pole body; 03 CYB5 sterol biosynthesis; microsome; 01 SPC97 microtubule nucleation; inner plaque of spindle pole body; outer plaque of spindle pole body; 03 SPC72 mitotic spindle elongation; nuclear migration (sensu Saccharomyces); mitotic chromosome segregation; microtubule nucleation; outer plaque of spindle pole body; 03 SPC110 microtubule nucleation; inner plaque of spindle pole body; central plaque of spindle pole body; 03 PSK2 protein amino acid phosphorylation; hexose metabolism; KAR1 karyogamy during conjugation with cellular fusion; spindle pole body duplication (sensu Saccharomyces); half bridge of spindle pole body; 14 03 SPC29 microtubule nucleation; spindle pole body duplication (sensu Saccharomyces); central plaque of spindle pole body; 03 MPS2 mitotic anaphase; spindle pole body duplication (sensu Saccharomyces); nuclear membrane; spindle pole body; 03 NUF2 microtubule nucleation; chromosome segregation; condensed nuclear chromosome kinetochore; condensed nuclear chromosome\, pericentric region; 03 SPC42 microtubule nucleation; spindle pole body duplication (sensu Saccharomyces); intermediate layer of spindle pole body; central plaque of spindle pole body; 03 LRS4 chromatin silencing at ribosomal DNA (rDNA); meiosis I\, chromosome segregation; nuclear chromosome; nucleus; nucleolus; 04 ECM11 cell wall organization and biogenesis; nucleus; MRP4 protein biosynthesis; mitochondrial small ribosomal subunit; 05 DRS2 intracellular protein transport; post-Golgi transport; Golgi membrane; trans-Golgi network transport vesicle; 08 ARF2 ER to Golgi transport; intra-Golgi transport; Golgi vesicle; cytosol; 06 08 SCM3 FAP1 SPP41 negative regulation of transcription from Pol II promoter; 04 HMO1 plasmid maintenance; nuclear chromatin; nucleus; cytoplasm; TOR2 regulation of cell cycle; G1 phase of mitotic cell cycle; cytoskeleton organization and biogenesis; ribosome biogenesis; signal transduction; Rho protein signal transduction; cell cycle dependent actin filament reorganization; vacuolar membrane; plasma membrane; 01 03 14 10 HOM3 methionine metabolism; threonine metabolism; homoserine biosynthesis; 01 YMR087W YIL089W SSL1 nucleotide-excision repair\, DNA duplex unwinding; nucleotide-excision repair; transcription initiation from Pol II promoter; negative regulation of transcription from Pol II promoter\, mitotic; nucleotide excision repair factor 3 complex; transcription factor TFIIH complex; 05 03 04 YOR215C WTM2 regulation of meiosis; nucleus; 04 RHO4 establishment of cell polarity (sensu Saccharomyces); actin filament organization; small GTPase mediated signal transduction; intracellular; 14 BEM4 establishment of cell polarity (sensu Saccharomyces); Rho protein signal transduction; actin cytoskeleton organization and biogenesis; 14 13 01 WTM1 regulation of meiosis; nucleus; 04 WSC2 cell wall organization and biogenesis; Rho protein signal transduction; response to heat; actin cytoskeleton organization and biogenesis; membrane fraction; cytoplasm; 01 RHO2 establishment of cell polarity (sensu Saccharomyces); actin filament organization; microtubule-based process; cell wall organization and biogenesis; small GTPase mediated signal transduction; intracellular; 10 14 01 BNI1 mitotic spindle orientation; establishment of cell polarity (sensu Saccharomyces); response to osmotic stress; actin filament organization; bud growth; polar budding; Rho protein signal transduction; mRNA localization\, intracellular; actin nucleation; incipient bud site; polarisome; actin cap (sensu Saccharomyces); actin filament; bud tip; bud neck; shmoo tip; 03 14 ROM2 establishment of cell polarity (sensu Saccharomyces); actin filament organization; cell wall organization and biogenesis; bud growth; small GTPase mediated signal transduction; bud tip; 01 14 GSC2 beta-1\,3 glucan biosynthesis; cell wall organization and biogenesis; actin cap (sensu Saccharomyces); 1\,3-beta-glucan synthase complex; 01 14 SAC7 small GTPase mediated signal transduction; cell cycle dependent actin filament reorganization; intracellular; 06 FKS1 beta-1\,3 glucan biosynthesis; cell wall organization and biogenesis; actin cap (sensu Saccharomyces); 1\,3-beta-glucan synthase complex; 01 LRG1 small GTPase mediated signal transduction; cell wall biosynthesis (sensu Fungi); 14 SKN7 transcription; response to osmotic stress; response to oxidative stress; nucleus; 14 10 03 11 04 CDC42 establishment of cell polarity (sensu Saccharomyces); signal transduction during conjugation with cellular fusion; exocytosis; apical bud growth; isotropic bud growth; pseudohyphal growth; invasive growth; Rho protein signal transduction; soluble fraction; plasma membrane; bud tip; bud neck; shmoo tip; 03 14 13 10 RSM7 protein biosynthesis; mitochondrial small ribosomal subunit; 05 TOM6 mitochondrial translocation; mitochondrial outer membrane translocase complex; 08 06 HOS4 histone deacetylation; negative regulation of meiosis; histone deacetylase complex; MRPL23 ribosomal large subunit assembly and maintenance; protein biosynthesis; mitochondrial large ribosomal subunit; 05 MRPS16 protein biosynthesis; mitochondrial small ribosomal subunit; 05 GPD2 glycerol metabolism; cytosol; 01 DIA2 invasive growth; DFR1 folic acid and derivative metabolism; cytosol; 01 YKL137W TAD2 tRNA modification; 04 MRP1 protein biosynthesis; mitochondrial small ribosomal subunit; 05 EDC2 deadenylation-dependent decapping; 04 MSY1 amino acid activation; mitochondrion; 05 RSM26 protein biosynthesis; mitochondrial small ribosomal subunit; 05 HRD1 ER-associated protein catabolism; endoplasmic reticulum membrane; 06 YCF1 cadmium ion transport; arsenite transport; bilirubin transport; response to mercury ion; vacuolar membrane; 11 08 MRPL33 protein biosynthesis; mitochondrial large ribosomal subunit; 05 SCS7 fatty acid metabolism; endoplasmic reticulum; 01 YGR102C ELA1 RNA elongation from Pol II promoter; transcription elongation factor complex; RSM22 protein biosynthesis; mitochondrial small ribosomal subunit; 05 YMR295C YNR036C 05 RSM19 protein biosynthesis; mitochondrial small ribosomal subunit; 05 MRPL10 protein biosynthesis; mitochondrial large ribosomal subunit; 05 ACP1 fatty acid biosynthesis; mitochondrion; 01 YMR157C SWS2 cytoplasm; mitochondrion; 05 PUS6 pseudouridine synthesis; tRNA modification; cytoplasm; mitochondrion; 04 MRPL19 protein biosynthesis; mitochondrial large ribosomal subunit; 05 YDR134C cell wall (sensu Fungi); MRPL4 protein biosynthesis; mitochondrial large ribosomal subunit; 05 MRPL3 protein biosynthesis; mitochondrial large ribosomal subunit; 05 YKR065C MRPL9 ribosomal large subunit assembly and maintenance; protein biosynthesis; mitochondrial large ribosomal subunit; 05 MRPL16 protein biosynthesis; mitochondrial large ribosomal subunit; 05 APT2 01 RML2 protein biosynthesis; fatty acid metabolism; mitochondrial large ribosomal subunit; 05 MRPL49 protein biosynthesis; mitochondrial large ribosomal subunit; 05 PET191 cytochrome c oxidase biogenesis; mitochondrial inner membrane; 06 02 MRPL8 mitochondrial genome maintenance; protein biosynthesis; mitochondrial large ribosomal subunit; 05 MRPL13 protein biosynthesis; mitochondrial large ribosomal subunit; 05 CYT2 cytochrome c-heme linkage; mitochondrial intermembrane space; MRPL7 protein biosynthesis; mitochondrial large ribosomal subunit; 05 MRPL1 protein biosynthesis; aerobic respiration; mitochondrial large ribosomal subunit; 05 MRPL6 protein biosynthesis; mitochondrial large ribosomal subunit; 05 MRPL15 protein biosynthesis; mitochondrial large ribosomal subunit; 05 IMG2 protein biosynthesis; mitochondrial large ribosomal subunit; 05 YGL068W 05 MRPL32 protein biosynthesis; mitochondrial large ribosomal subunit; 05 RSM18 protein biosynthesis; mitochondrial small ribosomal subunit; 05 SHY1 aerobic respiration; mitochondrial inner membrane; 02 PFD1 protein folding; cytoskeleton organization and biogenesis; prefoldin complex; 06 MTM1 transport; manganese ion transport; mitochondrion; mitochondrial inner membrane; 08 FMC1 protein complex assembly; mitochondrion; 01 MRPL31 protein biosynthesis; mitochondrial large ribosomal subunit; 05 PCM1 N-acetylglucosamine biosynthesis; cytoplasm; 01 YHR049W YCG1 mitotic chromosome condensation; nuclear condensin complex; 03 YKR074W cytoplasm; YIL064W MEF1 translational elongation; mitochondrion; 05 MRS1 Group I intron splicing; mitochondrion; 04 YGL220W PMP3 cation transport; plasma membrane; MST1 threonyl-tRNA aminoacylation; mitochondrion; 05 ISC10 sporulation; 03 GLG1 glycogen biosynthesis; 02 GCV3 one-carbon compound metabolism; mitochondrion; 01 YJL083W PHB1 replicative cell aging; proteolysis and peptidolysis; mitochondrion; mitochondrial inner membrane; 03 MRPS35 protein biosynthesis; aerobic respiration; mitochondrial small ribosomal subunit; 05 MRPL38 protein biosynthesis; mitochondrial large ribosomal subunit; 05 COX17 cytochrome c oxidase biogenesis; intracellular copper ion transport; mitochondrial intermembrane space; cytosol; 13 06 02 AYR1 phosphatidic acid biosynthesis; cytoplasm; endoplasmic reticulum; lipid particle; 14 01 ATP14 ATP synthesis coupled proton transport; proton-transporting ATP synthase complex\, coupling factor F(o) (sensu Eukarya); 13 08 02 YLR193C ECM19 cell wall organization and biogenesis; RNH203 ATX1 copper ion transport; high affinity iron ion transport; response to oxidative stress; cytosol; 13 11 YPL009C MRPL35 protein biosynthesis; mitochondrial large ribosomal subunit; 05 IES5 MRPL11 protein biosynthesis; mitochondrial large ribosomal subunit; 05 IMG1 protein biosynthesis; mitochondrial ribosome; 02 05 ATP16 ATP synthesis coupled proton transport; proton-transporting ATP synthase\, central stalk (sensu Eukarya); 13 02 08 MRPL36 protein biosynthesis; mitochondrial large ribosomal subunit; 05 MRPL27 protein biosynthesis; mitochondrial large ribosomal subunit; 05 YBR262C YHR198C MRPL24 protein biosynthesis; mitochondrial large ribosomal subunit; 05 MRP7 protein biosynthesis; mitochondrial large ribosomal subunit; 05 YML025C 05 YJR080C YLR168C 06 YER078C 06 YER077C CUP1-1 response to copper ion; cytosol; 11 CUP1-2 response to copper ion; cytosol; 11 COQ1 ubiquinone metabolism; mitochondrion; 01 YGL226W 02 YDR332W CIS1 regulation of CDK activity; 03 SPO7 nuclear organization and biogenesis; meiosis; sporulation (sensu Saccharomyces); integral to membrane; nuclear envelope-endoplasmic reticulum network; 14 03 YGR206W ECM34 cell wall organization and biogenesis; NEM1 nuclear organization and biogenesis; sporulation (sensu Saccharomyces); integral to membrane; nuclear envelope-endoplasmic reticulum network; 14 03 SGF73 histone acetylation; SAGA complex; 06 ### CLUSTER 5 ### 08 Cellular transport PEP5 Golgi to endosome transport; nonselective vesicle docking; homotypic vacuole fusion (non-autophagic); late endosome to vacuole transport; vacuolar membrane (sensu Fungi); 06 08 YBL010C YDR459C MATALPHA2 regulation of transcription from Pol II promoter; regulation of transcription\, mating-type specific; donor preference; nucleus; 14 04 UGO1 transport; mitochondrial fusion; mitochondrial outer membrane; CPD1 DNA metabolism; meiosis; 03 YIL174W YIL157C MPD1 protein folding; 06 DID2 protein-vacuolar targeting; cytoplasm; 06 08 ZRT2 low-affinity zinc ion transport; plasma membrane; 13 YOR086C VPS15 protein amino acid phosphorylation; protein-vacuolar targeting; vacuolar transport; protein-Golgi retention; Golgi membrane; 08 06 GDI1 vesicle-mediated transport; membrane fraction; soluble fraction; 08 SEC21 ER to Golgi transport; retrograde (Golgi to ER) transport; COPI vesicle coat; 08 SEC18 vacuole inheritance; ER to Golgi transport; cytoplasm; extrinsic to plasma membrane; 08 TLG2 nonselective vesicle fusion; Golgi trans cisterna; early endosome; Golgi trans face; 06 08 SNC1 Golgi to plasma membrane transport; endocytosis; nonselective vesicle fusion; transport vesicle; 08 SSO2 Golgi to plasma membrane transport; nonselective vesicle fusion; cytoplasm; endoplasmic reticulum; integral to plasma membrane; 08 14 SPO20 nonselective vesicle fusion; spore wall assembly (sensu Saccharomyces); prospore membrane; 14 08 SEC2 exocytosis; cytosol; cytoplasmic vesicle; 08 SEC9 Golgi to plasma membrane transport; nonselective vesicle fusion; membrane; 08 14 HRK1 cell ion homeostasis; EXO84 establishment of cell polarity (sensu Saccharomyces); nuclear mRNA splicing\, via spliceosome; cytokinesis; Golgi to plasma membrane transport; nonselective vesicle docking; nonselective vesicle fusion; polar budding; actin cap (sensu Saccharomyces); exocyst; 08 14 SEC15 establishment of cell polarity (sensu Saccharomyces); cytokinesis; Golgi to plasma membrane transport; nonselective vesicle docking; nonselective vesicle fusion; polar budding; actin cap (sensu Saccharomyces); exocyst; 08 14 SEC6 establishment of cell polarity (sensu Saccharomyces); cytokinesis; Golgi to plasma membrane transport; endocytosis; nonselective vesicle docking; nonselective vesicle fusion; polar budding; actin cap (sensu Saccharomyces); exocyst; 08 SEC10 establishment of cell polarity (sensu Saccharomyces); cytokinesis; Golgi to plasma membrane transport; nonselective vesicle docking; nonselective vesicle fusion; polar budding; actin cap (sensu Saccharomyces); exocyst; 08 SEC3 establishment of cell polarity (sensu Saccharomyces); cytokinesis; Golgi to plasma membrane transport; nonselective vesicle docking; nonselective vesicle fusion; polar budding; actin cap (sensu Saccharomyces); exocyst; 08 14 SEC5 establishment of cell polarity (sensu Saccharomyces); cytokinesis; Golgi to plasma membrane transport; nonselective vesicle docking; nonselective vesicle fusion; polar budding; actin cap (sensu Saccharomyces); exocyst; 08 SEC1 exocytosis; nonselective vesicle docking; nonselective vesicle fusion; actin cap (sensu Saccharomyces); 08 SEC4 cytokinesis; exocytosis; Golgi to plasma membrane transport; nonselective vesicle fusion; polar budding; small GTPase mediated signal transduction; actin cap (sensu Saccharomyces); transport vesicle; 14 08 VPS72 protein-vacuolar targeting; cytoplasm; SRO77 exocytosis; Golgi to plasma membrane transport; plasma membrane; 14 08 YCS4 mitotic chromosome condensation; nuclear condensin complex; VPS8 late endosome to vacuole transport; membrane fraction; 06 08 VPS41 high affinity iron ion transport; vacuole organization and biogenesis; protein transport; homotypic vacuole fusion (non-autophagic); vacuole (sensu Fungi); vacuolar membrane; 06 VPS33 Golgi to endosome transport; homotypic vacuole fusion (non-autophagic); late endosome to vacuole transport; vacuolar membrane (sensu Fungi); cytosol; 08 06 PEP3 Golgi to endosome transport; nonselective vesicle docking; homotypic vacuole fusion (non-autophagic); late endosome to vacuole transport; extrinsic to vacuolar membrane; vacuolar membrane (sensu Fungi); 08 06 YDR109C MCH2 transport; membrane; YNR047W response to pheromone; VAM6 vacuole organization and biogenesis; homotypic vacuole fusion (non-autophagic); vacuole (sensu Fungi); vacuolar membrane; 06 AAP1 ATP synthesis coupled proton transport; proton-transporting ATP synthase complex\, coupling factor F(o) (sensu Eukarya); 13 02 08 AUT7 08 06 VPS45 protein complex assembly; Golgi to vacuole transport; vacuole organization and biogenesis; osmoregulation; Golgi membrane; cytosol; extrinsic to membrane; 14 08 06 TLG1 nonselective vesicle fusion; Golgi trans cisterna; early endosome; Golgi trans face; 06 08 COG7 intra-Golgi transport; Golgi transport complex; 08 VTI1 intra-Golgi transport; Golgi to vacuole transport; nonselective vesicle fusion; endosome to lysosome transport; integral to Golgi membrane; 06 08 APL6 Golgi to vacuole transport; AP-3 adaptor complex; 08 SEC17 ER to Golgi transport; peripheral to membrane of membrane fraction; 08 NYV1 nonselective vesicle fusion; vacuolar membrane; 06 YKT6 intra-Golgi transport; nonselective vesicle fusion; membrane; 06 08 VAM7 Golgi to vacuole transport; nonselective vesicle fusion; vacuolar membrane (sensu Fungi); 08 PEP1 protein-vacuolar targeting; vacuolar transport; Golgi apparatus; 08 06 RIB5 vitamin B2 biosynthesis; soluble fraction; 01 PMC1 calcium ion transport; calcium ion homeostasis; vacuolar membrane (sensu Fungi); 13 08 NCP1 ergosterol biosynthesis; microsome; 01 11 MF(ALPHA)2 response to pheromone during conjugation with cellular fusion; extracellular; 14 MRPS17 protein biosynthesis; aerobic respiration; mitochondrial small ribosomal subunit; 05 SEC20 retrograde (Golgi to ER) transport; nonselective vesicle fusion; endoplasmic reticulum; endoplasmic reticulum membrane; 08 06 YPT6 intracellular protein transport; retrograde (endosome to Golgi) transport; Golgi apparatus; 08 VPS63 TIP20 retrograde (Golgi to ER) transport; endoplasmic reticulum; 08 SFT1 intra-Golgi transport; Golgi membrane; 08 GOS1 intra-Golgi transport; nonselective vesicle fusion; integral to membrane; 06 08 COG1 retrograde (vesicle recycling within Golgi) transport; intra-Golgi transport; Golgi transport complex; 08 COG3 retrograde (vesicle recycling within Golgi) transport; ER to Golgi transport; intra-Golgi transport; peripheral to membrane of membrane fraction; soluble fraction; Golgi transport complex; 08 SEC7 ER to Golgi transport; intra-Golgi transport; late endosome; Golgi vesicle; cytosol; 08 SED5 ER to Golgi transport; retrograde (Golgi to ER) transport; intra-Golgi transport; nonselective vesicle fusion; Golgi cis-face; 08 SLY1 ER to Golgi transport; endoplasmic reticulum; Golgi apparatus; ER-Golgi transport vesicle; 08 SEC28 ER to Golgi transport; nonselective vesicle coating; COPI vesicle coat; 08 06 SEC27 ER to Golgi transport; retrograde (Golgi to ER) transport; COPI vesicle coat; 08 BET1 ER to Golgi transport; retrograde (Golgi to ER) transport; endoplasmic reticulum membrane; COPII-coated vesicle; 08 ARF1 ER to Golgi transport; intra-Golgi transport; Golgi vesicle; cytosol; 06 08 SEC26 ER to Golgi transport; COPI vesicle coat; coated vesicle; 08 COP1 ER to Golgi transport; retrograde (Golgi to ER) transport; COPI vesicle coat; 08 RET2 ER to Golgi transport; retrograde (Golgi to ER) transport; COPI vesicle coat; 08 SEC22 ER to Golgi transport; retrograde (Golgi to ER) transport; intra-Golgi transport; nonselective vesicle fusion; endoplasmic reticulum; Golgi apparatus; integral to membrane; 08 BOS1 ER to Golgi transport; endoplasmic reticulum membrane; 08 SFB3 ER to Golgi transport; peripheral to membrane of membrane fraction; endoplasmic reticulum; COPII vesicle coat; SAR1 ER to Golgi transport; COPII vesicle coat; 08 SEC31 ER to Golgi transport; COPII vesicle coat; 08 EMP24 ER to Golgi transport; vesicle organization and biogenesis; endoplasmic reticulum; integral to membrane; COPII-coated vesicle; 08 SFB2 ER to Golgi transport; COPII vesicle coat; ERV25 ER to Golgi transport; COPII-coated vesicle; 08 SEC13 ER to Golgi transport; nonselective vesicle assembly; ER-associated protein catabolism; nuclear pore; cytoplasm; extrinsic to plasma membrane; COPII vesicle coat; 08 SEC12 ER to Golgi transport; ER-associated protein catabolism; integral to membrane of membrane fraction; integral to endoplasmic reticulum membrane; 08 SEC16 autophagy; vesicle-mediated transport; endoplasmic reticulum membrane; COPII vesicle coat; 06 08 MF(ALPHA)1 response to pheromone during conjugation with cellular fusion; extracellular; 14 SEC62 SRP-dependent cotranslational membrane targeting\, translocation; endoplasmic reticulum membrane; 06 08 EUG1 protein folding; endoplasmic reticulum; 06 SEC24 ER to Golgi transport; autophagy; COPII vesicle coat; 08 ORM1 response to unfolded protein; YIP5 membrane; YIP4 membrane; YPT31 exocytosis; vesicle-mediated transport; Golgi apparatus; 08 YPT1 protein complex assembly; ER to Golgi transport; Golgi membrane; endoplasmic reticulum membrane; 08 YPT10 Golgi organization and biogenesis; 08 TVP23 YPT32 exocytosis; vesicle-mediated transport; Golgi apparatus; 08 YGR223C VPS34 vacuole inheritance; protein amino acid phosphorylation; protein-vacuolar targeting; vacuolar transport; membrane fraction; 01 10 08 YIP1 vesicle-mediated transport; Golgi apparatus; membrane; 08 14 YPT7 vacuole inheritance; Golgi to vacuole transport; vesicle-mediated transport; vacuole; 08 YPT53 protein-vacuolar targeting; endocytosis; late endosome; 08 06 YDR018C phospholipid biosynthesis; CCZ1 autophagic vacuole fusion; protein-vacuolar targeting; autophagy; vacuolar transport; late endosome; vacuole; membrane; 11 YBL107C MSS4 actin cytoskeleton organization and biogenesis; actin cable assembly; plasma membrane; 14 01 10 BPH1 response to pH; 08 SAC2 08 LUV1 08 GYP6 intracellular protein transport; 08 VPS53 Golgi to vacuole transport; GARP complex; cytoplasm; Golgi apparatus; 08 VPS67 SGM1 SYS1 Golgi to endosome transport; vesicle organization and biogenesis; integral to Golgi membrane; 08 MDR1 soluble fraction; 04 11 APG16 06 APG12 06 YLR104W YDL053C 06 RHB1 L-arginine transport; L-lysine transport; extrinsic to plasma membrane; 10 AGE1 ER to Golgi transport; intra-Golgi transport; GCS1 ER to Golgi transport; retrograde (Golgi to ER) transport; cell cycle dependent actin filament reorganization; ER-Golgi intermediate compartment; cytoskeleton; 03 08 GLO3 ER to Golgi transport; retrograde (Golgi to ER) transport; ER-Golgi intermediate compartment; 03 04 RSR1 bud site selection; axial budding; polar budding; small GTPase mediated signal transduction; plasma membrane; bud; 14 GTS1 regulation of cell cycle; cellular morphogenesis; chronological cell aging; multidrug transport; sporulation (sensu Saccharomyces); ultradian rhythm; nucleus; cytoplasm; 03 11 14 04 SPS18 sporulation; 14 03 04 RAS2 replicative cell aging; pseudohyphal growth; sporulation (sensu Saccharomyces); adenylate cyclase activation; RAS protein signal transduction; plasma membrane; 01 13 10 14 11 03 AGE2 ER to Golgi transport; intra-Golgi transport; CDC25 regulation of cell cycle; start control point of mitotic cell cycle; RAS protein signal transduction; cytoplasm; plasma membrane; 01 03 13 STE6 peptide pheromone export; integral to plasma membrane; shmoo tip; 14 08 YMR323W cytoplasm; 02 01 YLR445W SDC25 RAS protein signal transduction; 03 IRA1 sporulation (sensu Saccharomyces); RAS protein signal transduction; membrane; 13 CYR1 regulation of cell cycle; meiosis; G-protein signaling\, coupled to cAMP nucleotide second messenger; RAS protein signal transduction; plasma membrane; 01 03 13 10 14 YDL218W cytoplasm; CDC2 leading strand elongation; lagging strand elongation; mutagenesis; base-excision repair; nucleotide-excision repair; mismatch repair; postreplication repair; delta DNA polymerase complex; 03 HYS2 leading strand elongation; lagging strand elongation; mutagenesis; base-excision repair; nucleotide-excision repair; mismatch repair; postreplication repair; delta DNA polymerase complex; 03 SIT4 G1/S transition of mitotic cell cycle; protein amino acid phosphorylation; cell wall organization and biogenesis; protein kinase cascade; actin cytoskeleton organization and biogenesis; 14 03 SSS1 cotranslational membrane targeting; translocon; 06 08 HMLALPHA1 regulation of transcription from Pol II promoter; regulation of transcription\, mating-type specific; nucleus; 04 14 SCJ1 protein folding; endoplasmic reticulum lumen; 06 KAR2 karyogamy during conjugation with cellular fusion; SRP-dependent cotranslational membrane targeting\, translocation; response to unfolded protein; endoplasmic reticulum lumen; 03 06 08 SEC72 SRP-dependent cotranslational membrane targeting\, translocation; endoplasmic reticulum membrane; 06 08 SEC61 SRP-dependent cotranslational membrane targeting\, translocation; translocon; endoplasmic reticulum lumen; endoplasmic reticulum membrane; 08 06 SEC66 SRP-dependent cotranslational membrane targeting\, translocation; endoplasmic reticulum membrane; 08 06 YOR223W NPL6 protein-nucleus import; nucleus; 06 SEC63 SRP-dependent cotranslational membrane targeting\, translocation; endoplasmic reticulum membrane; 06 08 IML2 CNS1 protein folding; cytoplasm; HSP60 protein folding; mitochondrial translocation; mitochondrion; 11 06 HCH1 protein folding; response to stress; YMR124W cytoplasm; CTF13 centromere/kinetochore complex maturation; condensed nuclear chromosome kinetochore; 03 STI1 protein folding; cytoplasm; 11 14 HSP10 protein folding; mitochondrial matrix; 06 STE11 signal transduction during conjugation with cellular fusion; protein amino acid phosphorylation; pseudohyphal growth; cytoplasm; 14 13 YOR256C CPR7 response to stress; cytosol; 14 04 06 CPR6 protein folding; cytoplasm; 06 04 SBA1 protein folding; nucleus; cytoplasm; 14 06 AHA1 protein folding; response to stress; cytoplasm; 06 11 PEP12 Golgi to vacuole transport; endosome; Golgi apparatus; 08 06 SSA3 protein folding; SRP-dependent cotranslational membrane targeting\, translocation; protein-mitochondrial targeting; response to stress; cytosol; 11 SSA1 protein-nucleus import\, translocation; protein folding; SRP-dependent cotranslational membrane targeting\, translocation; vacuolar membrane (sensu Fungi); nucleus; cytoplasm; cell wall (sensu Fungi); 06 11 08 TAH11 DNA replication licensing; nucleus; cytoplasm; 03 SSA4 protein folding; SRP-dependent cotranslational membrane targeting\, translocation; response to stress; nucleus; cytoplasm; 11 SSA2 protein folding; SRP-dependent cotranslational membrane targeting\, translocation; vacuolar membrane (sensu Fungi); cytoplasm; cell wall (sensu Fungi); 06 08 HSP104 protein folding; response to stress; nucleus; cytoplasm; 06 11 SIS1 translational initiation; cytosolic small ribosomal subunit (sensu Eukarya); 05 03 HSC82 protein folding; response to stress; 11 CIN1 post-chaperonin tubulin folding pathway; beta-tubulin folding; microtubule; 03 YDJ1 protein-mitochondrial targeting; cytosol; 08 03 06 11 CDC37 regulation of cell cycle; spindle pole body duplication (sensu Saccharomyces); signal transduction; 03 06 DJP1 peroxisome matrix protein import; cytosol; 08 06 CAJ1 06 YJL162C APA1 nucleotide metabolism; 01 TAT1 amino acid transport; plasma membrane; 01 08 SSB1 protein biosynthesis; soluble fraction; polysome; 05 XDJ1 06 HLJ1 06 TIM9 mitochondrial translocation; mitochondrial intermembrane space; mitochondrial intermembrane space protein transporter complex; 06 08 PET9 ATP/ADP exchange; mitochondrial inner membrane; 01 08 TIM22 mitochondrial translocation; mitochondrial inner membrane protein insertion complex; 06 08 MRS5 mitochondrial translocation; mitochondrial intermembrane space; mitochondrial inner membrane protein insertion complex; 06 08 TIM54 mitochondrial translocation; mitochondrial inner membrane protein insertion complex; 06 08 SPO14 phospholipid metabolism; exocytosis; sporulation (sensu Fungi); prospore membrane; endosome; 14 03 01 TIM8 mitochondrial translocation; mitochondrial intermembrane space protein transporter complex; 08 06 DNM1 mitochondrial fission; mitochondrial outer membrane; MAS6 mitochondrial translocation; mitochondrion; mitochondrial inner membrane pre-sequence translocase complex; 08 06 CYB2 electron transport; mitochondrial intermembrane space; 01 02 SSC1 protein folding; mitochondrial translocation; mitochondrion; mitochondrial inner membrane; 06 08 11 TIM13 mitochondrial translocation; mitochondrial intermembrane space; mitochondrial intermembrane space protein transporter complex; 06 TIM44 mitochondrial translocation; mitochondrial matrix; 06 08 TIM17 mitochondrial translocation; mitochondrial inner membrane pre-sequence translocase complex; 06 08 MRS11 mitochondrial translocation; mitochondrial intermembrane space; mitochondrial intermembrane space protein transporter complex; 06 08 MDJ1 protein folding; proteolysis and peptidolysis; mitochondrial inner membrane; 06 11 TOM20 mitochondrial translocation; mitochondrial outer membrane translocase complex; 06 08 TOM70 mitochondrial translocation; mitochondrial outer membrane translocase complex; 06 08 TOM7 mitochondrial translocation; mitochondrial outer membrane translocase complex; 06 08 TOM40 mitochondrial translocation; mitochondrion; mitochondrial outer membrane translocase complex; 08 06 YDR307W 01 06 YJR115W YML087C 02 YDL099W MET14 sulfate assimilation; methionine metabolism; cell; 01 SRN2 protein-membrane targeting; protein-vacuolar targeting; endosome; 04 08 YDR132C NUP116 tRNA splicing; mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; protein-nucleus import; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 08 04 KAP95 protein-nucleus import; nuclear pore; cytoplasm; 08 06 RRP7 ribosomal small subunit assembly and maintenance; 35S primary transcript processing; 04 05 06 YRA1 mRNA-nucleus export; transcription export complex; 04 YGR081C LYS12 lysine biosynthesis; cytoplasm; mitochondrion; 01 GON7 response to dessication; PDA1 pyruvate metabolism; mitochondrion; pyruvate dehydrogenase complex; 01 02 DAM1 mitotic spindle assembly (sensu Saccharomyces); condensed nuclear chromosome kinetochore; spindle; kinetochore microtubule; 03 KTI12 cell growth and/or maintenance; carbon utilization; DNA-directed RNA polymerase II\, holoenzyme; 11 NDC1 RNA-nucleus export; protein-nucleus import; microtubule nucleation; spindle pole body duplication (sensu Saccharomyces); nuclear pore; spindle pole body; 03 POM152 mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 08 MDS3 sporulation; cytoplasm; 14 KIN2 membrane fraction; CSM3 meiotic chromosome segregation; YML059C YAL061W 01 02 ACA1 transcription initiation from Pol II promoter; nucleus; 04 YAP1 transcription; response to oxidative stress; response to drug; nucleus; cytoplasm; 04 11 NUP53 protein-nucleus import\, docking; mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 08 GFA1 cell wall chitin biosynthesis; 01 14 YIG1 14 SPO12 mitotic cell cycle; regulation of exit from mitosis; meiosis I; nucleus; nucleolus; 03 14 SOR1 fructose metabolism; mannose metabolism; 01 NMA2 nicotinamide adenine dinucleotide metabolism; nucleus; 01 UFD4 protein polyubiquitination; protein monoubiquitination; cytoplasm; 06 THI4 DNA repair; thiamin biosynthesis; mitochondrion; 01 03 SHE2 mRNA localization\, intracellular; cytoplasm; 14 CSE1 protein-nucleus export; nuclear membrane; 08 06 XPT1 purine nucleotide biosynthesis; 01 STS1 ubiquitin-dependent protein catabolism; chromosome segregation; nucleus; 04 08 YGR024C GLE2 mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; protein-nucleus import; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear membrane organization and biogenesis; nuclear pore organization and biogenesis; nuclear pore; 04 08 TVP15 PHO13 protein amino acid dephosphorylation; histone dephosphorylation; 01 YER010C YBR137W cytoplasm; HPA3 histone acetylation; 03 06 YCR076C NIF3 04 RRF1 protein biosynthesis; mitochondrion; 05 BIT61 YJR056C YJL218W 01 SOR2 01 MNS1 N-linked glycosylation; endoplasmic reticulum; 01 06 MBB1 DUT1 pyrimidine deoxyribonucleoside triphosphate catabolism; 01 GSP1 rRNA processing; nucleocytoplasmic transport; nuclear organization and biogenesis; nucleus; cytoplasm; 04 08 KAP122 protein-nucleus import; response to drug; nuclear pore; cytoplasm; 06 08 GLE1 poly(A)+ mRNA-nucleus export; nuclear pore; 08 04 MET13 sulfur amino acid biosynthesis; protein biosynthesis; methionine metabolism; cell; mitochondrial large ribosomal subunit; 01 05 GPI8 attachment of GPI anchor to protein; integral to endoplasmic reticulum membrane; 06 01 NIC96 mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; protein-nucleus import; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 08 ERG27 ergosterol biosynthesis; endoplasmic reticulum; endoplasmic reticulum membrane; 01 SAC3 mRNA-nucleus export; protein-nucleus export; mitosis; actin filament-based process; RNA nuclear export complex; 01 04 SXM1 mRNA-nucleus export; nucleocytoplasmic transport; nucleus; 04 08 NUP170 protein-nucleus import\, docking; mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; chromosome segregation; nuclear pore; 08 03 NUP159 ribosome-nucleus export; mRNA-nucleus export; rRNA-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 08 NSP1 ribosomal large subunit-nucleus export; RNA-nucleus export; mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; protein-nucleus import; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 04 08 SPO74 sporulation (sensu Saccharomyces); spindle pole body; NUP60 protein-nucleus import\, docking; nucleocytoplasmic transport; nuclear pore; 08 NUP2 mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 08 NUP100 mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 04 08 IES3 YLR016C NUP133 mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 14 08 04 PNP1 purine nucleoside catabolism; 01 NUP82 mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 08 04 MSN5 protein-nucleus export; nucleus; 14 08 NUP84 mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear membrane organization and biogenesis; nuclear pore organization and biogenesis; nuclear pore; 14 08 NUP145 tRNA splicing; mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; protein-nucleus import; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 04 08 NUP85 mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear membrane organization and biogenesis; nuclear pore organization and biogenesis; nuclear pore; 04 08 14 NUP120 mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 04 08 SEH1 mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 08 14 NUP57 mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; protein-nucleus import; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 08 NUP49 ribosomal large subunit-nucleus export; tRNA splicing; mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; protein-nucleus import; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear membrane; nuclear pore; 04 08 NUP42 mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 04 08 PAB1 regulation of translational initiation; nucleus; cytoplasm; ribosome; 04 05 NUP188 mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 08 PIB1 protein ubiquitination; vacuolar membrane (sensu Fungi); late endosome; 01 LOS1 tRNA splicing; tRNA-nucleus export; nuclear matrix; 04 PIM1 proteolysis and peptidolysis; response to heat; mitochondrial matrix; 06 04 YRB2 mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 08 MOG1 protein-nucleus import; nucleus; 06 08 YRB1 G1/S transition of mitotic cell cycle; RNA-nucleus export; ubiquitin-dependent protein catabolism; protein-nucleus import; nucleus; cytoplasm; 04 08 SRM1 ribosome-nucleus export; rRNA-nucleus export; nucleus; 14 04 08 NTF2 protein-nucleus import; nucleocytoplasmic transport; nuclear membrane; 08 APG14 06 YBP1 response to oxidative stress; GSH1 glutathione biosynthesis; response to cadmium ion; intracellular; 11 CRM1 ribosomal large subunit-nucleus export; mRNA-nucleus export; protein-nucleus export; nucleus; 04 08 STO1 nuclear mRNA splicing\, via spliceosome; commitment complex; snRNA cap binding complex; 04 SRP1 nucleocytoplasmic transport; nucleus; cytoplasm; 06 08 PSE1 mRNA-nucleus export; nucleus; cytoplasm; 08 PEX19 protein-peroxisome targeting; peroxisome organization and biogenesis; cytosol; RNA15 mRNA polyadenylation; mRNA cleavage; mRNA cleavage factor complex; 04 PCF11 transcription termination from Pol II promoter; mRNA polyadenylation; mRNA cleavage; mRNA cleavage factor complex; 04 AEP1 protein biosynthesis; 04 05 TCM10 protein complex assembly; mitochondrial inner membrane; NAB2 mRNA polyadenylation; poly(A)+ mRNA-nucleus export; nucleus; cytoplasm; 04 RNA14 mRNA polyadenylation; mRNA cleavage; nucleus; mitochondrion; mRNA cleavage factor complex; 04 NAM7 mRNA catabolism\, nonsense-mediated; mRNA catabolism; regulation of translational termination; cytoplasm; polysome; 05 01 KAP104 protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; cell cycle; cytosol; 08 TIR1 response to stress; cell wall (sensu Fungi); 11 VID27 NSR1 ribosomal small subunit assembly and maintenance; rRNA processing; nucleus; nucleolus; 11 04 MLP2 protein-nucleus import; nuclear membrane; nucleoplasm; 08 ASM4 protein-nucleus import\, docking; mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 03 ECM31 pantothenate biosynthesis; 01 YBL055C ISN1 YKR017C PGI1 gluconeogenesis; glycolysis; pentose-phosphate shunt; cytosol; 02 01 BLM3 membrane; NUP157 mRNA-nucleus export; rRNA-nucleus export; snRNA-nucleus export; tRNA-nucleus export; NLS-bearing substrate-nucleus import; snRNP protein-nucleus import; mRNA-binding (hnRNP) protein-nucleus import; ribosomal protein-nucleus import; protein-nucleus export; nuclear pore organization and biogenesis; nuclear pore; 08 YBR270C UPF3 mRNA catabolism\, nonsense-mediated; mRNA catabolism; cytoplasm; polysome; 01 05 NMD2 mRNA catabolism\, nonsense-mediated; mRNA catabolism; cytoplasm; polysome; 01 05 NMD5 protein-nucleus import; nucleus; cytoplasm; 01 NMD4 mRNA catabolism\, nonsense-mediated; 01 MUM2 premeiotic DNA synthesis; 14 03 YDR527W EDE1 endocytosis; actin cortical patch (sensu Saccharomyces); bud tip; bud neck; ZDS2 chromatin silencing at ribosomal DNA (rDNA); establishment of cell polarity (sensu Saccharomyces); cell aging; nucleus; 14 03 EDC3 EBS1 telomerase-dependent telomere maintenance; nucleus; 03 YMR132C YBR094W AEP2 protein biosynthesis; mitochondrion; 05 02 01 YMR184W GPT2 phospholipid biosynthesis; cytoplasm; endoplasmic reticulum; ### CLUSTER 6 ### 04 Transcription/RNA processing/RNA transport PDR10 multidrug transport; plasma membrane; SNC2 Golgi to plasma membrane transport; endocytosis; nonselective vesicle fusion; transport vesicle; 08 06 OCT1 mitochondrial processing; iron ion homeostasis; mitochondrion; 06 13 SCD5 endocytosis; actin filament organization; protein secretion; peripheral to membrane of membrane fraction; actin cortical patch (sensu Saccharomyces); 08 06 MIP1 DNA dependent DNA replication; mitochondrion; 03 PPZ1 sodium ion homeostasis; nucleus; cytoplasm; 11 GLC7 cellular morphogenesis during vegetative growth; glycogen metabolism; regulation of carbohydrate metabolism; 35S primary transcript processing; mitotic spindle checkpoint; meiosis; response to heat; transcription termination from Pol II promoter\, poly(A) coupled; transcription termination from Pol II promoter\, poly(A) independent; protein phosphatase type 1 complex; nucleolus; mRNA cleavage and polyadenylation specificity factor complex; bud neck; 01 02 14 05 03 YGL232W VMA22 glycogen metabolism; protein complex assembly; vacuolar acidification; endoplasmic reticulum membrane; 06 YFR041C 06 YJL206C 04 VPH1 polyphosphate metabolism; vacuolar acidification; hydrogen-transporting ATPase V0 domain; vacuole; 13 08 06 STV1 vacuolar acidification; hydrogen-transporting ATPase V0 domain; endosome; Golgi apparatus; 13 08 TFP1 intron homing; vacuolar acidification; protein metabolism; hydrogen-transporting ATPase V1 domain; vacuolar membrane (sensu Fungi); 13 08 06 VMA8 vacuolar acidification; hydrogen-transporting ATPase V1 domain; vacuolar membrane (sensu Fungi); 13 08 VMA7 vacuolar acidification; hydrogen-transporting ATPase V1 domain; vacuolar membrane (sensu Fungi); 13 08 VMA5 vacuolar acidification; hydrogen-transporting ATPase V1 domain; vacuolar membrane (sensu Fungi); 13 08 06 VMA10 glycogen metabolism; vacuolar acidification; hydrogen-transporting ATPase V1 domain; 13 08 VMA6 vacuolar transport; vacuolar acidification; hydrogen-transporting ATPase V0 domain; vacuolar membrane; 13 08 06 VMA21 protein complex assembly; endoplasmic reticulum; endoplasmic reticulum membrane; 06 RAV1 vacuolar acidification; hydrogen-transporting ATPase V1 domain; cytoplasm; 02 VMA2 vacuolar acidification; hydrogen-transporting ATPase V1 domain; cytoplasm; 08 13 YBR159W fatty acid elongation; endoplasmic reticulum; integral to membrane; 01 YBR184W CDS1 phosphatidylglycerol biosynthesis; phosphatidylserine metabolism; mitochondrion; endoplasmic reticulum; 01 MDV1 mitochondrial genome maintenance; mitochondrial fission; mitochondrial outer membrane; YMR265C COX18 cytochrome c oxidase biogenesis; mitochondrial inner membrane; integral to membrane; 02 06 SYN8 transport; endosome; 08 06 GIP1 spore wall assembly (sensu Saccharomyces); protein phosphatase type 1 complex; prospore membrane; 03 14 04 GIP2 protein amino acid dephosphorylation; protein phosphatase type 1 complex; 01 02 FIN1 nucleus; spindle pole body; 03 REG1 negative regulation of transcription from Pol II promoter; glycogen metabolism; regulation of carbohydrate metabolism; cell growth and/or maintenance; protein phosphatase type 1 complex; cytoplasm; 01 04 SNF1 glucose metabolism; regulation of carbohydrate metabolism; protein amino acid phosphorylation; cellular response to nitrogen starvation; cell adhesion; signal transduction; filamentous growth; vacuole (sensu Fungi); nucleus; cytoplasm; 11 01 SIP1 protein amino acid phosphorylation; signal transduction; vacuole; 01 SNF4 regulation of transcription from Pol II promoter; peroxisome organization and biogenesis; nucleus; cytoplasm; plasma membrane; 04 11 01 GAL83 protein amino acid phosphorylation; cell adhesion; signal transduction; filamentous growth; nucleus; 01 04 NRG2 invasive growth; nucleus; YFR057W YER130C 04 NRG1 glucose metabolism; regulation of transcription from Pol II promoter; invasive growth; response to pH; nucleus; 01 04 TUP1 negative regulation of transcription; nucleus; 04 CYC8 negative regulation of transcription; nucleus; 04 PSD2 phosphatidylcholine biosynthesis; Golgi membrane; vacuolar membrane (sensu Fungi); 01 YGP1 response to stress; response to nutrients; cell wall (sensu Fungi); 11 CSR1 cell wall organization and biogenesis; phospholipid transport; cytoplasm; microsome; cytosol; 01 HOG1 protein amino acid phosphorylation; hyperosmotic response; positive regulation of transcription from Pol II promoter; nucleus; cytoplasm; 01 11 13 YGR266W plasma membrane; AVT5 transport; YAR066W RRM3 DNA replication; nuclear telomeric heterochromatin; 03 DIE2 N-linked glycosylation; dolichol-linked oligosaccharide biosynthesis; endoplasmic reticulum membrane; 01 BRE2 chromatin silencing at telomere; transcription; histone methylation; nuclear chromatin; SWD3 chromatin silencing at telomere; histone methylation; nuclear chromatin; SWD1 chromatin silencing at telomere; histone methylation; nuclear chromatin; 04 03 SHG1 histone methylation; SDC1 chromatin silencing at telomere; histone methylation; nuclear chromatin; SET1 chromatin silencing at telomere; histone methylation; nucleus; 14 03 PTI1 mRNA polyadenylation; mRNA cleavage; transcription termination from Pol II promoter\, poly(A) coupled; transcription termination from Pol II promoter\, poly(A) independent; mRNA cleavage and polyadenylation specificity factor complex; POP8 rRNA processing; tRNA processing; ribonuclease MRP complex; nucleolar ribonuclease P complex; 04 ATS1 microtubule-based process; 03 RTT106 negative regulation of DNA transposition; HSP26 protein folding; response to stress; nucleus; cytoplasm; 06 11 YLR408C SSU72 35S primary transcript processing; transcription initiation from Pol II promoter; transcription termination from Pol II promoter; snoRNA transcription; transcription termination from Pol II promoter\, poly(A) coupled; transcription termination from Pol II promoter\, poly(A) independent; nucleus; mRNA cleavage and polyadenylation specificity factor complex; 04 YGL159W PFS2 mRNA polyadenylation; mRNA cleavage; mRNA cleavage and polyadenylation specificity factor complex; 04 MPD2 protein folding; endoplasmic reticulum; 06 REF2 mRNA processing; transcription termination from Pol II promoter\, poly(A) coupled; transcription termination from Pol II promoter\, poly(A) independent; mRNA cleavage and polyadenylation specificity factor complex; 04 PTA1 mRNA polyadenylation; mRNA cleavage; tRNA processing; transcription termination from Pol II promoter\, poly(A) coupled; transcription termination from Pol II promoter\, poly(A) independent; mRNA cleavage and polyadenylation specificity factor complex; mRNA cleavage factor complex; 04 CFT1 transcription termination from Pol II promoter; mRNA polyadenylation; mRNA cleavage; mRNA cleavage and polyadenylation specificity factor complex; mRNA cleavage factor complex; 04 MPE1 mRNA polyadenylation; mRNA cleavage; mRNA cleavage and polyadenylation specificity factor complex; PAP1 mRNA polyadenylation; nucleoplasm; mRNA cleavage and polyadenylation specificity factor complex; 04 FIP1 mRNA polyadenylation; mRNA cleavage; mRNA cleavage and polyadenylation specificity factor complex; 04 YSH1 mRNA polyadenylation; mRNA cleavage; mRNA cleavage and polyadenylation specificity factor complex; mRNA cleavage factor complex; 04 CFT2 mRNA polyadenylation; mRNA cleavage; mRNA cleavage and polyadenylation specificity factor complex; mRNA cleavage factor complex; 04 SWD2 histone methylation; transcription termination from Pol II promoter\, poly(A) coupled; transcription termination from Pol II promoter\, poly(A) independent; mRNA cleavage and polyadenylation specificity factor complex; UFD1 mRNA processing; ubiquitin-dependent protein catabolism; protein transport; endoplasmic reticulum; 06 PRM8 conjugation with cellular fusion; endoplasmic reticulum; integral to membrane; CNA1 adaptation to pheromone during conjugation with cellular fusion; cell ion homeostasis; cell wall organization and biogenesis; cytoplasm; 14 04 13 CMP2 adaptation to pheromone during conjugation with cellular fusion; cell ion homeostasis; cytoplasm; 14 04 PPZ2 sodium ion homeostasis; 11 YKL161C 14 11 03 13 SIS2 G1/S transition of mitotic cell cycle; regulation of mitotic cell cycle; salinity response; coenzyme A biosynthesis; nucleus; cytoplasm; 03 04 MST27 vesicle organization and biogenesis; endoplasmic reticulum; Golgi apparatus; integral to membrane; PPM1 C-terminal protein amino acid methylation; 06 MST28 vesicle organization and biogenesis; endoplasmic reticulum; Golgi apparatus; integral to membrane; YHC3 regulation of pH; intracellular protein transport; vacuole (sensu Fungi); CPR4 membrane; 06 LRE1 cell wall organization and biogenesis; response to heat; cell wall (sensu Fungi); KCS1 response to stress; vacuole organization and biogenesis; 04 YBR090C YFL052W 04 01 RPN1 ubiquitin-dependent protein catabolism; cytoplasm; endoplasmic reticulum; proteasome regulatory particle (sensu Eukarya); 06 KKQ8 MRK1 protein amino acid phosphorylation; proteolysis and peptidolysis; response to stress; YDR466W SPS2 sporulation (sensu Saccharomyces); cell wall (sensu Fungi); 14 03 SPS1 protein amino acid phosphorylation; sporulation (sensu Saccharomyces); 03 14 MLC1 mitochondrion inheritance; vacuole inheritance; establishment of cell polarity (sensu Saccharomyces); cytokinesis; endocytosis; apical bud growth; isotropic bud growth; vesicle-mediated transport; actin cap (sensu Saccharomyces); 14 03 FRQ1 membrane; 10 TPK3 protein amino acid phosphorylation; pseudohyphal growth; cytoplasm; cAMP-dependent protein kinase complex; 10 04 BCY1 response to stress; pseudohyphal growth; signal transduction; response to heat; nucleus; cytoplasm; 01 14 04 11 CMK1 protein amino acid phosphorylation; signal transduction; cytoplasm; 14 10 YPK1 protein amino acid phosphorylation; sphingolipid metabolism; endocytosis; cytosol; plasma membrane; bud neck; YKL171W proteolysis and peptidolysis; cytoplasm; TPK1 protein amino acid phosphorylation; pseudohyphal growth; RAS protein signal transduction; cytoplasm; cAMP-dependent protein kinase complex; 04 10 IRE1 myo-inositol metabolism; protein amino acid phosphorylation; unfolded protein response\, activation of signaling protein kinase/endonuclease; unfolded protein response\, cleavage of primary transcript encoding UFP-specific transcription factor; nuclear membrane; endoplasmic reticulum membrane; 01 10 11 SCH9 age dependent response to oxidative stress during chronological cell aging; protein amino acid phosphorylation; regulation of cell size; 03 14 13 HAL5 cation homeostasis; 11 ELM1 cytokinesis; protein amino acid phosphorylation; response to osmotic stress; bud growth; axial budding; pseudohyphal growth; contractile ring (sensu Saccharomyces); 03 14 CNB1 adaptation to pheromone during conjugation with cellular fusion; cell ion homeostasis; cell wall organization and biogenesis; cytoplasm; 13 04 14 CKB2 G1/S transition of mitotic cell cycle; G2/M transition of mitotic cell cycle; flocculation; establishment of cell polarity (sensu Saccharomyces); regulation of transcription from Pol I promoter; regulation of transcription from Pol III promoter; protein amino acid phosphorylation; cell ion homeostasis; response to DNA damage stimulus; protein kinase CK2 complex; 04 ASE1 mitotic anaphase B; mitotic spindle assembly; spindle microtubule; nuclear microtubule; 03 CKB1 G1/S transition of mitotic cell cycle; G2/M transition of mitotic cell cycle; flocculation; establishment of cell polarity (sensu Saccharomyces); regulation of transcription from Pol I promoter; regulation of transcription from Pol III promoter; protein amino acid phosphorylation; cell ion homeostasis; response to DNA damage stimulus; protein kinase CK2 complex; 04 14 CKA1 G1/S transition of mitotic cell cycle; G2/M transition of mitotic cell cycle; flocculation; establishment of cell polarity (sensu Saccharomyces); regulation of transcription from Pol I promoter; regulation of transcription from Pol III promoter; protein amino acid phosphorylation; cell ion homeostasis; response to DNA damage stimulus; protein kinase CK2 complex; 04 14 03 YTA7 protein catabolism; 06 YKL088W salinity response; coenzyme A biosynthesis; 11 UTP22 processing of 20S pre-rRNA; PHO12 01 TFB3 nucleotide-excision repair\, DNA duplex unwinding; nucleotide-excision repair; transcription initiation from Pol II promoter; negative regulation of transcription from Pol II promoter\, mitotic; nucleotide excision repair factor 3 complex; transcription factor TFIIH complex; 04 03 06 KIN28 transcription initiation from Pol II promoter; protein amino acid phosphorylation; negative regulation of transcription from Pol II promoter\, mitotic; transcription factor TFIIH complex; 04 03 VHS1 G1/S transition of mitotic cell cycle; protein amino acid phosphorylation; 03 06 KIN1 membrane fraction; PRR2 MAPKKK cascade; PSK1 protein amino acid phosphorylation; hexose metabolism; 06 01 YBR028C SAT4 G1/S transition of mitotic cell cycle; cation homeostasis; 11 YDL025C 11 KIN3 chromosome segregation; 14 AKL1 06 LRO1 triacylglycerol biosynthesis; lipid storage; endoplasmic reticulum; 01 PYK2 pyruvate metabolism; glycolysis; cytosol; 01 02 KIC1 cellular morphogenesis; cell wall organization and biogenesis; 03 YNR014W cytoplasm; UBR1 protein polyubiquitination; protein monoubiquitination; proteasome complex (sensu Eukarya); 06 UBC11 protein polyubiquitination; protein monoubiquitination; cytoplasm; 06 USO1 protein complex assembly; ER to Golgi transport; soluble fraction; 08 YML072C BAS1 histidine biosynthesis; transcription from Pol II promoter; purine base biosynthesis; nucleus; 01 04 YGR150C PEX4 protein polyubiquitination; protein monoubiquitination; peroxisome organization and biogenesis; peroxisome; 06 SET4 YNL083W transport; mitochondrial inner membrane; 08 ITT1 regulation of translational termination; CDC31 microtubule nucleation; spindle pole body duplication (sensu Saccharomyces); nuclear pore; half bridge of spindle pole body; 03 ULP2 plasmid maintenance; mitotic spindle checkpoint; protein desumoylation; nucleus; 06 03 RTT101 negative regulation of DNA transposition; ubiquitin-dependent protein catabolism; regulation of mitosis; MIP6 mRNA-nucleus export; nuclear pore; 04 05 RNP1 ribosome biogenesis and assembly; cytoplasm; YBR042C phospholipid biosynthesis; 01 UIP5 nuclear membrane; PES4 DNA dependent DNA replication; 03 SFL1 negative regulation of transcription from Pol II promoter; nuclear chromosome; 04 TAF8 transcription from Pol II promoter; nucleus; transcription factor TFIID complex; 04 RHO5 Rho protein signal transduction; 14 VAM3 Golgi to vacuole transport; nonselective vesicle fusion; vacuolar membrane; 06 08 APS3 Golgi to vacuole transport; AP-3 adaptor complex; 08 APM3 Golgi to vacuole transport; AP-3 adaptor complex; 08 TPK2 protein amino acid phosphorylation; pseudohyphal growth; RAS protein signal transduction; cytoplasm; cAMP-dependent protein kinase complex; 04 13 APL5 Golgi to vacuole transport; AP-3 adaptor complex; 08 YPL184C CUP9 transcription initiation from Pol II promoter; copper ion homeostasis; nucleus; 13 04 PCI8 protein deneddylation; signalosome complex; MKC7 proteolysis and peptidolysis; cell wall (sensu Fungi); 06 YAP3 regulation of transcription from Pol II promoter; nucleus; 04 KEX1 protein processing; Golgi trans face; 06 HMRA1 regulation of transcription\, mating-type specific; nucleus; 14 BUR6 negative regulation of transcription from Pol II promoter; nucleus; 04 SAN1 establishment and/or maintenance of chromatin architecture; 14 UBP13 06 YDR111C 01 MNL1 ER-associated protein catabolism; endoplasmic reticulum; 01 UBP9 protein deubiquitination; cytoplasm; 06 ABD1 mRNA capping; nucleus; DNA-directed RNA polymerase II\, holoenzyme; 04 FUN14 ### CLUSTER 7 ### 01 Metabolism LYS9 lysine biosynthesis\, aminoadipic pathway; cytoplasm; 01 UGA3 regulation of transcription from Pol II promoter; nitrogen utilization; nucleus; 01 04 ACS1 acetyl-CoA biosynthesis; acetate fermentation; cytosol; 02 01 GDH3 glutamate biosynthesis; soluble fraction; nucleus; 01 AGX1 glyoxylate cycle; 01 PCK1 gluconeogenesis; cytosol; 01 02 STL1 transport; membrane; 01 SFC1 fumarate transport; succinate transport; mitochondrial inner membrane; 01 08 ICL1 glyoxylate cycle; 02 01 IDP2 isocitrate metabolism; glutamate biosynthesis; cytosol; 02 01 CSM2 meiotic chromosome segregation; ADY2 DNA metabolism; transport; meiosis; nitrogen utilization; membrane; 01 SIP4 regulation of transcription from Pol II promoter; positive regulation of gluconeogenesis; nucleus; 04 YKL222C 04 PSY3 MIG1 glucose metabolism; regulation of transcription from Pol II promoter; nucleus; cytoplasm; 01 04 MSH3 removal of nonhomologous ends; mismatch repair; DNA recombination; mitotic recombination; nuclear chromosome; 03 TAF5 G1-specific transcription in mitotic cell cycle; establishment and/or maintenance of chromatin architecture; transcription initiation from Pol II promoter; protein amino acid acetylation; chromatin modification; histone acetylation; SAGA complex; transcription factor TFIID complex; 04 YBR284W 01 MRC1 DNA replication checkpoint; chromatin silencing at HML and HMR (sensu Saccharomyces); chromatin silencing at telomere; BUD31 bud site selection; YEL043W YDL057W YFL051C YER152C OXA1 mitochondrial translocation; mitochondrial inner membrane; 02 06 SPI1 cell wall (sensu Fungi); AGP3 amino acid transport; plasma membrane; 01 AAD16 aldehyde metabolism; 01 02 ENT2 actin cortical patch assembly; endocytosis; actin filament organization; actin cortical patch (sensu Saccharomyces); 08 14 YRA2 poly(A)+ mRNA-nucleus export; nucleus; 04 YKL195W YLR290C STP3 01 04 IML3 chromosome segregation; condensed nuclear chromosome kinetochore; 03 FBP1 gluconeogenesis; cytosol; 01 02 YER182W YDR338C COS12 YKL050C SPC19 mitotic spindle assembly (sensu Saccharomyces); microtubule nucleation; condensed nuclear chromosome kinetochore; spindle pole body; spindle; 03 RRD1 DNA repair; response to osmotic stress; mitotic spindle assembly; cell fraction; cytosol; 03 YPL282C YOR391C YKL107W SNO4 FIS1 mitochondrial fission; mitochondrial outer membrane; YLR159W YJR149W 01 YBR139W 06 YGR205W cytoplasm; YMR160W YLR283W YAR023C UIP3 nuclear membrane; RNR1 DNA replication; cytoplasm; 01 03 YGL176C GND2 glucose metabolism; cytosol; 01 02 RNR4 DNA replication; nucleus; cytoplasm; 01 03 CRC1 fatty acid metabolism; mitochondrion; mitochondrial inner membrane; 08 ALD4 ethanol metabolism; mitochondrion; 02 RNR3 DNA replication; cytoplasm; 03 01 NGL3 PHM7 CYT1 oxidative phosphorylation; mitochondrial electron transport\, ubiquinol to cytochrome c; mitochondrial inner membrane; mitochondrial electron transport chain; respiratory chain complex III (sensu Eukarya); 02 MLH3 mismatch repair; meiotic recombination; nucleus; 03 LEE1 SMK1 protein amino acid phosphorylation; spore wall assembly (sensu Saccharomyces); 10 14 PRO2 proline biosynthesis; cytoplasm; 01 YPL201C COG2 retrograde (vesicle recycling within Golgi) transport; ER to Golgi transport; intra-Golgi transport; peripheral to membrane of membrane fraction; soluble fraction; Golgi transport complex; 08 SDH1 tricarboxylic acid cycle; mitochondrial electron transport\, succinate to ubiquinone; respiratory chain complex II (sensu Eukarya); 01 02 COR1 aerobic respiration; respiratory chain complex III (sensu Eukarya); 02 YJL045W cellular respiration; mitochondrion; 01 02 AVT3 neutral amino acid transport; vacuole; SDH3 tricarboxylic acid cycle; mitochondrial electron transport\, succinate to ubiquinone; respiratory chain complex II (sensu Eukarya); 02 TCM62 protein complex assembly; mitochondrial inner membrane; 06 11 SDH4 tricarboxylic acid cycle; mitochondrial electron transport\, succinate to ubiquinone; respiratory chain complex II (sensu Eukarya); 02 01 YGR067C 04 SSH4 01 PEX8 protein-peroxisome targeting; peroxisome organization and biogenesis; peroxisomal membrane; peroxisomal matrix; INM1 myo-inositol metabolism; 01 10 YRR1 multidrug transport; positive regulation of transcription from Pol II promoter; nucleus; 04 JEN1 lactate transport; plasma membrane; 01 PXA2 fatty acid transport; integral to peroxisomal membrane; 01 08 HXT5 hexose transport; plasma membrane; 01 08 YGR243W YFL040W 01 YAT2 alcohol metabolism; carnitine metabolism; 01 08 TMT1 cytosol; GIT1 phospholipid transport; plasma membrane; 01 APA2 nucleotide metabolism; 01 YIL024C YBR147W YIL087C EDS1 04 ABM1 YMR206W YDL199C 01 AUT1 06 08 RTN2 HSP12 hyperosmotic response; response to oxidative stress; cell adhesion; response to dessication; response to heat; 01 03 11 13 REG2 negative regulation of transcription from Pol II promoter; cell growth and/or maintenance; protein phosphatase type 1 complex; 01 YKR016W 02 SDH2 tricarboxylic acid cycle; mitochondrial electron transport\, succinate to ubiquinone; respiratory chain complex II (sensu Eukarya); 02 OM45 mitochondrial outer membrane; STF1 ATP synthesis coupled proton transport; proton-transporting ATP synthase complex (sensu Eukarya); 02 YDR306C ubiquitin-dependent protein catabolism; ubiquitin ligase complex; YDL091C YPS5 YIL172C 01 02 RPN14 QCR9 mitochondrial electron transport\, ubiquinol to cytochrome c; aerobic respiration; iron-sulfur cluster assembly; respiratory chain complex III (sensu Eukarya); 02 YJL017W YPS6 cell wall (sensu Fungi); 06 PIG2 01 02 YDR288W YJL103C 04 QCR10 mitochondrial electron transport\, ubiquinol to cytochrome c; aerobic respiration; respiratory chain complex III (sensu Eukarya); 02 FBP26 gluconeogenesis; cytosol; 01 YGR110W SPG1 PET130 05 POT1 fatty acid beta-oxidation; peroxisomal matrix; 01 02 MBR1 aerobic respiration; 04 YDR070C ACH1 acetate metabolism; acetyl-CoA metabolism; mitochondrion; cytosol; 01 14 NDE2 NADH oxidation; ethanol fermentation; mitochondrion; 02 MOH1 UGX2 PDH1 propionate metabolism; YJR096W arabinose metabolism; D-xylose metabolism; cytoplasm; 01 YDR262W QCR8 mitochondrial electron transport\, ubiquinol to cytochrome c; aerobic respiration; respiratory chain complex III (sensu Eukarya); 02 AAC3 ATP/ADP exchange; mitochondrial inner membrane; 01 08 YKR049C GPX1 response to oxidative stress; 11 YLR312C AAC1 ATP/ADP exchange; mitochondrial inner membrane; 08 01 YLR164W mitochondrial inner membrane; 02 01 ISF1 aerobic respiration; 01 YNL200C YNL195C YMR107W GRE1 response to stress; response to dessication; cytoplasm; 11 YOR019W MMT2 iron ion homeostasis; mitochondrion; integral to membrane; 13 08 YIL042C mitochondrion; 01 VHS3 G1/S transition of mitotic cell cycle; coenzyme A biosynthesis; 11 TOS8 13 DDR2 response to stress; 11 YOL083W AVO1 regulation of cell growth; cytoplasm; ODC1 mitochondrial transport; mitochondrion; mitochondrial inner membrane; 08 DBP1 mRNA processing; 04 YMR114C YMR191W WHI2 response to stress; regulation of growth; 14 RDS2 response to xenobiotic stimulus; 04 YJR008W YJL161W YGR111W YBR280C YDR533C soluble fraction; YOR289W YOR352W DGA1 triacylglycerol biosynthesis; lipid storage; lipid particle; IDP3 isocitrate metabolism; fatty acid beta-oxidation; NADPH regeneration; cytoplasm; peroxisome; 01 02 PEX10 peroxisome organization and biogenesis; peroxisomal membrane; 06 YJL185C CYC3 cytochrome c-heme linkage; mitochondrial intermembrane space; 01 06 RHR2 glycerol biosynthesis; response to osmotic stress; 01 YJL037W PET100 cytochrome c oxidase biogenesis; aerobic respiration; mitochondrial inner membrane; 06 02 FUN34 transport; nitrogen utilization; membrane; integral to membrane; 01 TPP1 ASP3-4 asparagine catabolism; cellular response to nitrogen starvation; periplasmic space (sensu Fungi); 01 NDI1 mitochondrial electron transport\, NADH to ubiquinone; respiratory chain complex I (sensu Eukarya); 02 SIP5 cellular response to glucose starvation; cytoplasm; RIM11 protein amino acid phosphorylation; proteolysis and peptidolysis; response to stress; sporulation (sensu Saccharomyces); 03 04 YMR155W PRP12 mitochondrial genome maintenance; rRNA processing; mitochondrial inner membrane; 04 PAI3 vacuolar protein catabolism; cytoplasm; 06 11 CRS5 response to metal ion; cytoplasm; 13 11 VPS21 protein-vacuolar targeting; endocytosis; late endosome; 06 08 YOR220W YOR059C lipid particle; YNG1 chromatin modification; histone acetylation; histone acetyltransferase complex; nuclear nucleosome; 06 YKL218C 01 SRL3 nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism; cytoplasm; BOP2 YKL133C YLR161W GID8 negative regulation of gluconeogenesis; YLR327C 06 YKL187C KNS1 protein amino acid phosphorylation; SOD1 superoxide metabolism; copper ion homeostasis; zinc ion homeostasis; mitochondrial intermembrane space; cytosol; 11 MRS4 transport; RNA splicing; mitochondrion; 04 08 YJR114W VPS62 protein-vacuolar targeting; 08 06 STR2 sulfur metabolism; 01 TES1 fatty acid oxidation; peroxisome; 01 STP2 positive regulation of transcription from Pol II promoter; nucleus; 04 YJR079W SEF1 14 04 YGR201C 05 YLR454W MDG1 signal transduction during conjugation with cellular fusion; plasma membrane; 10 14 13 CAT8 gluconeogenesis; positive regulation of transcription from Pol II promoter; nucleus; 02 04 01 ECM4 cell wall organization and biogenesis; YMR085W YLR271W PBN1 protein processing; endoplasmic reticulum; 06 YOL153C 01 06 IRA2 RAS protein signal transduction; 01 PEX18 protein-peroxisome targeting; peroxisome; cytosol; 06 08 YER067W TSA2 regulation of redox homeostasis; nucleus; 11 01 BDH1 butanediol fermentation; cytoplasm; 01 NVJ1 microautophagy; nuclear membrane; 08 FAA2 N-terminal protein myristoylation; lipid metabolism; peroxisome; 01 08 URA8 phospholipid biosynthesis; pyrimidine base biosynthesis; cytosol; 01 CAT2 carnitine metabolism; mitochondrion; peroxisome; peroxisomal matrix; 08 01 SOD2 oxygen and reactive oxygen species metabolism; mitochondrion; mitochondrial matrix; 11 YNL157W PEX15 protein-peroxisome targeting; peroxisome organization and biogenesis; peroxisomal membrane; 08 YDR282C SIP18 response to osmotic stress; response to dessication; soluble fraction; 11 YLR149C MSC1 meiotic recombination; 03 HOR2 carbohydrate metabolism; glycerol biosynthesis; response to osmotic stress; 01 11 FOX2 fatty acid beta-oxidation; peroxisomal matrix; 01 02 YOL015W UIP4 nuclear membrane; CAD1 positive regulation of transcription from Pol II promoter; response to cadmium ion; nucleus; 11 04 YFR045W transport; mitochondrial inner membrane; APJ1 06 MPM1 membrane fraction; mitochondrion; YNL193W YNL187W DOT6 chromatin silencing at ribosomal DNA (rDNA); chromatin silencing at telomere; regulation of transcription from Pol II promoter; cell elongation; filamentous growth; 04 CUE4 cytoplasm; CPT1 phosphatidylcholine biosynthesis; endoplasmic reticulum; 01 EPT1 phosphatidylethanolamine biosynthesis; endoplasmic reticulum; 08 01 MUC1 pseudohyphal growth; invasive growth; cell-cell adhesion; filamentous growth; plasma membrane; 01 YML083C HMS2 pseudohyphal growth; 04 11 AGP1 amino acid transport; plasma membrane; 01 MEP1 ammonium transport; plasma membrane; 08 RGM1 negative regulation of transcription from Pol II promoter; nucleus; 04 MSS11 starch catabolism; pseudohyphal growth; positive regulation of transcription from Pol II promoter; nucleus; 04 MGA1 filamentous growth; 11 04 MEP2 pseudohyphal growth; ammonium transport; plasma membrane; 08 GZF3 negative regulation of transcription from Pol II promoter; nitrogen metabolism; regulation of nitrogen utilization; nucleus; 01 04 GAT1 transcription initiation from Pol II promoter; regulation of nitrogen utilization; nucleus; 04 01 YDL222C cell wall organization and biogenesis; cell cortex; integral to membrane; RCN1 calcium-mediated signaling; calcineurin complex; 13 04 DAL5 allantoate transport; plasma membrane; 08 DAL80 transcription; regulation of nitrogen utilization; nucleus; 01 04 DAL7 allantoin catabolism; cytoplasm; 01 02 DAL3 allantoin catabolism; membrane; 01 TOR1 regulation of cell cycle; G1 phase of mitotic cell cycle; ribosome biogenesis; meiosis; signal transduction; Golgi membrane; vacuolar membrane; plasma membrane; endosome membrane; 01 10 03 05 UGA2 glutamate catabolism; response to oxidative stress; 01 PUT3 proline catabolism; positive regulation of transcription from Pol II promoter; nucleus; 01 04 PUT2 glutamate biosynthesis; proline catabolism; mitochondrion; 01 ALD5 electron transport; mitochondrion; 02 CHA1 threonine catabolism; serine family amino acid catabolism; 01 DUR1,2 urea metabolism; 01 DAL81 regulation of transcription from Pol II promoter; nitrogen utilization; nucleus; 01 04 DAL4 allantoin transport; membrane; 08 DAL2 allantoin catabolism; 01 DUR3 urea transport; plasma membrane; 13 DAL1 allantoin catabolism; intracellular; 01 GLN3 nitrogen metabolism; regulation of nitrogen utilization; positive regulation of transcription from Pol II promoter; nucleus; cytosol; 01 04 FUR4 uracil transport; plasma membrane; 08 01 RFA2 DNA unwinding; DNA replication\, priming; DNA strand elongation; nucleotide-excision repair; postreplication repair; double-strand break repair; DNA recombination; DNA replication factor A complex; 03 MCK1 mitotic chromosome segregation; double-strand break repair via nonhomologous end-joining; protein amino acid phosphorylation; response to stress; meiosis; sporulation (sensu Saccharomyces); soluble fraction; 14 03 ATP12 protein complex assembly; mitochondrial matrix; 06 YNL194C cytoplasm; endoplasmic reticulum; cell cortex; integral to membrane; YLL056C NAB6 COX19 cytochrome c oxidase biogenesis; metal ion transport; mitochondrial intermembrane space; cytosol; FYV10 negative regulation of gluconeogenesis; XBP1 response to stress; nucleus; 04 MEF2 translational elongation; mitochondrion; 05 YFL054C water transport; integral to membrane; RIM4 premeiotic DNA synthesis; meiosis; meiotic recombination; sporulation; cytoplasm; 03 14 CAK1 protein amino acid phosphorylation; cell cycle; meiosis; cytoplasm; 03 WWM1 response to dessication; cytoplasm; 14 HVG1 08 MAL11 alpha-glucoside transport; trehalose transport; membrane fraction; 01 YAT1 alcohol metabolism; carnitine metabolism; mitochondrion; 01 08 COX12 cytochrome c oxidase biogenesis; respiratory chain complex IV (sensu Eukarya); 06 02 HIP1 manganese ion transport; L-histidine transport; plasma membrane; 01 08 13 YLR346C YCR045C 06 FLO5 flocculation; cell wall (sensu Fungi); 04 MAL33 carbohydrate metabolism; regulation of transcription\, DNA-dependent; nucleus; 01 04 CAN1 basic amino acid transport; plasma membrane; 01 08 MRPS18 protein biosynthesis; mitochondrial small ribosomal subunit; 05 MHP1 microtubule stabilization; cell wall organization and biogenesis; microtubule; HEM12 heme biosynthesis; 01 AUA1 amino acid transport; 01 YLL055W YJL084C cytoplasm; NPR1 regulation of nitrogen utilization; cytoplasm; 01 08 MTF1 transcription from mitochondrial promoter; mitochondrial matrix; 04 03 PUF3 mRNA catabolism\, deadenylation-dependent; cytoplasm; 01 GAP1 amino acid transport; integral to plasma membrane; 01 08 UGA4 transport; membrane; 01 08 GDH2 nitrogen metabolism; soluble fraction; 01 SIA1 proton transport; YKR018C YML002W HSP150 cell wall organization and biogenesis; cell wall (sensu Fungi); 14 11 YDL124W 01 MRF1 protein biosynthesis; translational termination; mitochondrion; 05 ETR1 fatty acid biosynthesis; aerobic respiration; mitochondrion; 02 RPO41 mitochondrial genome maintenance; transcription from mitochondrial promoter; mitochondrial matrix; 03 04 GPI10 GPI anchor biosynthesis; integral to membrane; 01 ### CLUSTER 8 ### 01 Metabolism AUT4 08 APG7 14 GGA1 Golgi to vacuole transport; Golgi trans face; SET6 YJL163C CVT19 08 YOL048C YMR110C BET3 ER to Golgi transport; TRAPP; 08 MDH1 tricarboxylic acid cycle; malate metabolism; mitochondrial matrix; 01 02 CIT2 glyoxylate cycle; citrate metabolism; glutamate biosynthesis; peroxisome; 02 01 YAP1801 endocytosis; actin cortical patch (sensu Saccharomyces); 06 08 14 PRX1 regulation of redox homeostasis; mitochondrion; 11 COS1 MET6 methionine biosynthesis; 01 CIT1 tricarboxylic acid cycle; citrate metabolism; glutamate biosynthesis; mitochondrion; mitochondrial matrix; 02 01 IDH1 tricarboxylic acid cycle; isocitrate metabolism; glutamate biosynthesis; mitochondrial matrix; 02 01 04 ACO1 tricarboxylic acid cycle; citrate metabolism; glutamate biosynthesis; propionate metabolism; mitochondrial matrix; cytosol; 02 01 YLR152C ECM7 cell wall organization and biogenesis; integral to membrane; STE24 peptide pheromone maturation; integral to endoplasmic reticulum membrane; 14 06 OSM1 metabolism; cytoplasm; 02 11 CPR3 protein folding; mitochondrion; 06 COS9 BGL2 cell wall organization and biogenesis; cell wall (sensu Fungi); 01 PTM1 02 COS2 YDC1 ceramide metabolism; response to heat; endoplasmic reticulum; 01 RIB1 vitamin B2 biosynthesis; 01 PKH2 MAPKKK cascade (cell wall biogenesis); protein amino acid phosphorylation; nucleus; NCE103 cytoplasm; 08 CCW14 cell wall organization and biogenesis; cell wall (sensu Fungi); YGR004W YDL089W SFH1 chromatin modeling; nucleosome remodeling complex; 04 03 YLR345W 01 02 DCS1 deadenylation-dependent decapping; YKL091C nucleus; PRP45 positive regulation of transcription from Pol II promoter; nucleus; 04 KIN82 protein amino acid phosphorylation; response to pheromone; YDR387C 01 PSP1 GSY1 glycogen metabolism; 02 01 GLG2 glycogen biosynthesis; 01 02 YIR044C YIR016W YIR043C SVP26 YIL151C YMR002W YOR052C GLO1 glutathione metabolism; 01 BAG7 small GTPase mediated signal transduction; intracellular; 06 YNK1 purine nucleotide biosynthesis; DNA metabolism; nucleotide metabolism; RNA metabolism; mitochondrial intermembrane space; cytosol; 01 YIR041W YJR085C PAU6 11 SUB1 transcription termination from Pol II promoter; positive regulation of transcription from Pol II promoter; nucleus; 04 YBR004C FAR3 cell cycle arrest in response to pheromone; 13 14 03 YMR196W YHR115C cytoplasm; YFR006W 06 LCB5 sphingolipid metabolism; response to heat; calcium-mediated signaling; membrane fraction; soluble fraction; 01 PIN2 YMR030W calcium-mediated signaling; YGR149W integral to membrane; YDR107C membrane fraction; 08 NPL4 ER-associated protein catabolism; endoplasmic reticulum; nuclear envelope-endoplasmic reticulum network; 06 08 CDC48 ubiquitin-dependent protein catabolism; nonselective vesicle fusion; apoptosis; cell cycle; protein transport; ER-associated protein catabolism; nucleus; endoplasmic reticulum; microsome; cytosol; 06 03 YFR007W LPP1 phospholipid metabolism; membrane; 01 TRR2 response to oxidative stress; mitochondrion; 01 DOT5 regulation of redox homeostasis; nucleus; 04 GRE3 response to stress; arabinose metabolism; D-xylose metabolism; 01 11 ALD3 polyamine catabolism; response to stress; beta-alanine biosynthesis; cytoplasm; 02 YKL151C NTH1 trehalose catabolism; response to stress; 01 02 SYM1 ALD2 aldehyde metabolism; polyamine catabolism; beta-alanine biosynthesis; cytoplasm; 02 YLR356W 03 YEL047C metabolism; cytoplasm; 02 PGM2 glucose 1-phosphate utilization; glucose 6-phosphate utilization; cytosol; 01 02 GAD1 glutamate catabolism; response to oxidative stress; cytoplasm; 01 YBR074W GIS3 intracellular signaling cascade; AUT10 UGA1 nitrogen utilization; intracellular; 01 EMI2 cytoplasm; 01 YHR209W XKS1 xylulose catabolism; 01 COX20 cytochrome c oxidase biogenesis; aerobic respiration; protein processing; mitochondrial inner membrane; 02 DOA1 double-strand break repair via nonhomologous end-joining; ubiquitin-dependent protein catabolism; 01 06 VPS13 protein-Golgi retention; late endosome to vacuole transport; extrinsic to membrane; 06 PDX3 fatty acid metabolism; 01 YLL023C YGR168C YDR287W myo-inositol metabolism; 10 01 YLR042C cell wall (sensu Fungi); DAN2 cell wall (sensu Fungi); SOL4 04 YBR056W 01 YBR053C TRR1 regulation of redox homeostasis; cytoplasm; 01 YGL059W YER079W YOR228C ECM39 protein amino acid glycosylation; dolichol-linked oligosaccharide biosynthesis; YLR343W END3 actin cortical patch assembly; cytokinesis; endocytosis; actin filament organization; polar budding; actin cortical patch (sensu Saccharomyces); 14 08 YNL208W YFR044C cytoplasm; GAS5 cell wall (sensu Fungi); YMR291W PRC1 vacuolar protein catabolism; cytoplasm; endoplasmic reticulum; 06 PRB1 vacuolar protein catabolism; cellular response to starvation; sporulation; vacuole (sensu Fungi); 06 PLB1 glycerophospholipid metabolism; cell wall (sensu Fungi); 01 MET17 methionine metabolism; cytoplasm; 01 STF2 response to dessication; ATP synthesis coupled proton transport; proton-transporting ATP synthase complex (sensu Eukarya); 02 ARA1 carbohydrate metabolism; cytosol; 01 YFR026C PAU4 11 YNL274C metabolism; 01 YGK3 protein amino acid phosphorylation; proteolysis and peptidolysis; response to stress; HXK1 fructose metabolism; cytosol; 01 02 YMR041C TSL1 trehalose biosynthesis; response to stress; alpha\,alpha-trehalose-phosphate synthase complex (UDP-forming); 01 02 MCR1 electron transport; ergosterol biosynthesis; response to oxidative stress; mitochondrial outer membrane; mitochondrial intermembrane space; 02 UGP1 UDP-glucose metabolism; protein amino acid glycosylation; 01 02 06 PGM1 glucose 1-phosphate utilization; glucose 6-phosphate utilization; cytosol; 02 01 VPH2 protein complex assembly; vacuolar acidification; endoplasmic reticulum membrane; 06 BNA5 nicotinamide adenine dinucleotide biosynthesis; 01 YKL121W YBR022W GSP2 nuclear organization and biogenesis; nucleus; 04 08 MPH1 DNA repair; nucleus; 03 11 PLB3 phosphatidylserine catabolism; phosphoinositide metabolism; extracellular; plasma membrane; 01 CSE2 mitotic chromosome segregation; transcription from Pol II promoter; mediator complex; 03 04 YOR152C EMI5 YBR052C BNA1 nicotinamide adenine dinucleotide biosynthesis; cytoplasm; 01 YDR248C 01 SAP1 06 SUP35 translational termination; cytosol; 03 05 HSP78 mitochondrial genome maintenance; protein folding; mitochondrial translocation; response to stress; mitochondrial matrix; 11 06 HSP42 response to stress; cytoskeleton organization and biogenesis; cytoplasm; cytoskeleton; 06 YHL021C CTT1 response to stress; cytoplasm; 11 TPS1 carbohydrate metabolism; response to stress; cytoplasm; alpha\,alpha-trehalose-phosphate synthase complex (UDP-forming); 01 11 02 SSE2 protein folding; 11 NTH2 trehalose catabolism; response to stress; 01 02 YBR287W PAU3 11 PRY2 YGL261C YGR212W GPD1 intracellular accumulation of glycerol; cytoplasm; 01 11 13 DAN3 cell wall (sensu Fungi); YAL068C TPS2 carbohydrate metabolism; response to stress; alpha\,alpha-trehalose-phosphate synthase complex (UDP-forming); 01 02 11 YBR071W cytoplasm; GRX1 response to oxidative stress; regulation of redox homeostasis; cytoplasm; 11 YDL110C YDL010W 01 YKL224C YGL157W 01 KTR2 cell wall mannoprotein biosynthesis; N-linked glycosylation; Golgi apparatus; 01 YLR257W cytoplasm; YLR194C cell wall (sensu Fungi); YPS1 protein processing; cell wall (sensu Fungi); 06 YLL064C ORM2 response to unfolded protein; YKR011C PDI1 protein folding; endoplasmic reticulum lumen; 01 06 YDL072C endoplasmic reticulum; PAM1 pseudohyphal growth; 14 11 YDR542W PAU2 11 SAP4 G1/S transition of mitotic cell cycle; cytoplasm; 03 MSP1 mitochondrial translocation; mitochondrial outer membrane; 06 08 PNC1 chromatin silencing at ribosomal DNA (rDNA); chromatin silencing at telomere; cell aging; nicotinate nucleotide biosynthesis\, salvage pathway; nucleus; cytoplasm; peroxisome; YER053C vacuole (sensu Fungi); mitochondrion; 01 GLK1 carbohydrate metabolism; cytosol; 01 08 02 YHL046C 11 YHR097C YIR014W YIL176C PAU1 11 YET1 LAP4 vacuolar protein catabolism; vacuole (sensu Fungi); 06 YHR087W YJL213W YGR294W YGR043C 01 02 PFK26 fructose 2\,6-bisphosphate metabolism; regulation of glycolysis; cytoplasm; 01 OPI3 phosphatidylcholine biosynthesis; endoplasmic reticulum; 01 PRM5 conjugation with cellular fusion; integral to membrane; GTT1 glutathione metabolism; endoplasmic reticulum; 11 SNA3 vacuolar lumen (sensu Fungi); membrane; COS5 COS8 response to unfolded protein; nuclear membrane; COS6 COS4 AMS1 carbohydrate metabolism; vacuolar membrane; 01 GSY2 glycogen metabolism; cytoplasm; 01 02 YPS3 protein metabolism; plasma membrane; 06 TFS1 regulation of proteolysis and peptidolysis; soluble fraction; 03 13 YGR127W EMP46 ER to Golgi transport; Golgi membrane; YLL025W UTH1 mitochondrion organization and biogenesis; mitochondrial outer membrane; cell wall (sensu Fungi); 03 14 11 MRP8 protein biosynthesis; mitochondrial ribosome; 05 YLR414C COS3 PBI2 regulation of proteolysis and peptidolysis; vacuole fusion (non-autophagic); vacuole (sensu Fungi); cytoplasm; 06 CHS1 budding; plasma membrane; chitosome; 01 14 03 YMR040W integral to membrane; DIA1 pseudohyphal growth; invasive growth; cytoplasm; YMR315W YIP3 ER to Golgi transport; COPII-coated vesicle; 08 CHS3 cytokinesis; cell wall chitin biosynthesis; response to osmotic stress; contractile ring (sensu Saccharomyces); 01 14 CHS2 cytokinesis; response to osmotic stress; contractile ring (sensu Saccharomyces); 14 01 YGR237C ERV29 ER to Golgi transport; COPII-coated vesicle; ERD2 protein-ER retention; integral to endoplasmic reticulum membrane; 06 08 YDL173W BSD2 protein-vacuolar targeting; metal ion transport; endoplasmic reticulum; 13 YER004W YAL049C YMR251W YMR090W HOR7 response to stress; membrane fraction; cell wall (sensu Fungi); 11 PTK2 G1/S transition of mitotic cell cycle; cell ion homeostasis; polyamine transport; nucleus; cytoplasm; 08 13 COX14 cytochrome c oxidase biogenesis; aerobic respiration; mitochondrial membrane; integral to membrane; 02 06 POR2 ion transport; mitochondrion; mitochondrial outer membrane; 08 YCL049C PDE1 cAMP-mediated signaling; 01 PPQ1 regulation of translation; protein amino acid dephosphorylation; 05 YPK2 protein amino acid phosphorylation; nucleus; cytoplasm; 03 YMR278W 01 GCY1 salinity response; arabinose metabolism; D-xylose metabolism; 01 YBR230C FAR7 cell cycle arrest in response to pheromone; 13 03 YJR107W 01 ROM1 establishment of cell polarity (sensu Saccharomyces); actin filament organization; cell wall organization and biogenesis; bud growth; small GTPase mediated signal transduction; intracellular; 14 01 MID2 cellular morphogenesis during conjugation; cell wall organization and biogenesis; integral to plasma membrane; 14 03 HSL7 regulation of cell cycle; G2/M transition of mitotic cell cycle; bud neck; 14 03 YEL001C MET30 ubiquitin-dependent protein catabolism; cell cycle; protein ubiquitination; nuclear ubiquitin ligase complex; SCF ubiquitin ligase complex; 01 04 06 03 MCM21 chromosome segregation; condensed nuclear chromosome kinetochore; 03 MET28 sulfur amino acid biosynthesis; regulation of transcription from Pol II promoter; regulation of sulfur metabolism; nucleus; 01 04 CBP1 mRNA catabolism; aerobic respiration; mitochondrion; 04 ICL2 threonine catabolism; propionate metabolism; mitochondrial matrix; 01 02 PTP2 inactivation of MAPK (osmolarity sensing); signal transduction during conjugation with cellular fusion; protein amino acid dephosphorylation; osmosensory signaling pathway; nucleus; 14 03 13 11 ECM17 sulfate assimilation; cell wall organization and biogenesis; 01 MET32 sulfur amino acid metabolism; nucleus; 01 04 CBF1 DNA replication and chromosome cycle; methionine biosynthesis; kinetochore; nucleus; 01 03 04 MET4 sulfur amino acid metabolism; positive regulation of transcription from Pol II promoter; nucleus; 01 04 EFT1 translational elongation; ribosome; 05 ZWF1 pentose-phosphate shunt; cytoplasm; 02 11 01 TKL2 pentose-phosphate shunt; 01 02 TAL1 pentose-phosphate shunt; cytoplasm; 01 02 BMH2 activation of MAPK (pseudohyphal growth); glycogen metabolism; pseudohyphal growth; sporulation (sensu Saccharomyces); RAS protein signal transduction; nucleus; 03 10 14 BMH1 activation of MAPK (pseudohyphal growth); glycogen metabolism; pseudohyphal growth; sporulation (sensu Saccharomyces); RAS protein signal transduction; nucleus; 03 10 14 URA10 pyrimidine base biosynthesis; 01 SLS1 protein biosynthesis; aerobic respiration; mitochondrial inner membrane; integral to membrane; mitochondrial nucleoid; 04 YNR074C response to singlet oxygen; plasma membrane; PDR12 transport; organic acid transport; propionate metabolism; plasma membrane; ISU1 iron ion homeostasis; iron-sulfur cluster assembly; mitochondrion; mitochondrial matrix; 01 SNF12 chromatin modeling; nucleosome remodeling complex; SWI/SNF complex; 04 KES1 steroid biosynthesis; vesicle-mediated transport; 08 01 NTG2 base-excision repair\, AP site formation; nucleus; 03 APN1 DNA repair; base-excision repair; nucleus; mitochondrion; 03 NTG1 DNA repair; base-excision repair\, AP site formation; nucleus; mitochondrion; 11 03 REV7 mutagenesis; DNA repair; nucleus; 03 RAD30 DNA replication; DNA repair; bypass DNA synthesis; replication fork; 03 HYR1 response to oxidative stress; intracellular; 11 YKL061W PKH1 MAPKKK cascade (cell wall biogenesis); protein amino acid phosphorylation; endocytosis; cytosol; YJL171C cell wall (sensu Fungi); DCW1 cell wall biosynthesis (sensu Fungi); membrane fraction; extrinsic to plasma membrane\, GPI-anchored; PAU5 11 DOG2 glucose metabolism; response to stress; cytoplasm; 01 YJR054W FMN1 FMN biosynthesis; mitochondrial inner membrane; microsome; YBR096W RIB4 vitamin B2 biosynthesis; 01 ARV1 sterol transport; sterol metabolism; endoplasmic reticulum; Golgi apparatus; integral to membrane; PEP4 vacuolar protein catabolism; cellular response to starvation; microautophagy; sporulation; vacuole (sensu Fungi); 06 LAT1 pyruvate metabolism; mitochondrion; 02 01 UTR1 iron ion homeostasis; nicotinamide adenine dinucleotide phosphorylation and dephosphorylation; 13 GPR1 pseudohyphal growth; G-protein coupled receptor protein signaling pathway; plasma membrane; 10 14 13 GPB2 signal transduction; 10 GPA2 pseudohyphal growth; sporulation (sensu Saccharomyces); signal transduction; cell growth and/or maintenance; 14 13 10 USE1 retrograde (Golgi to ER) transport; endoplasmic reticulum; IES1 YHR113W cytoplasm; 06 THI11 thiamin biosynthesis; 01 PBP2 04 GIS4 intracellular signaling cascade; YFL044C ECM21 cell wall organization and biogenesis; PST2 11 YLR297W MTL1 cell wall organization and biogenesis; integral to plasma membrane; 14 03 YNL115C GPM2 gluconeogenesis; glycolysis; cytoplasm; cytosol; 01 02 RMD12 HXT16 hexose transport; plasma membrane; 08 01 YHR138C vacuole fusion (non-autophagic); CTA1 oxygen and reactive oxygen species metabolism; peroxisomal matrix; 11 GUT2 carbohydrate metabolism; NADH oxidation; mitochondrion; 01 GPG1 signal transduction; 10 ICS2 DIA3 pseudohyphal growth; invasive growth; 01 ESBP6 transport; mitochondrion; membrane; ECM37 cell wall organization and biogenesis; AI5_BETA mitochondrion; KTR5 N-linked glycosylation; cell wall organization and biogenesis; Golgi apparatus; 01 06 YUR1 cell wall mannoprotein biosynthesis; N-linked glycosylation; Golgi apparatus; 01 KTR7 N-linked glycosylation; cell wall organization and biogenesis; Golgi apparatus; 06 01 MNN2 protein amino acid glycosylation; Golgi apparatus; 14 KRE2 cell wall mannoprotein biosynthesis; N-glycan processing; O-linked glycosylation; Golgi apparatus; 01 06 KTR4 N-linked glycosylation; Golgi apparatus; 01 06 KTR3 N-linked glycosylation; O-linked glycosylation; cell wall organization and biogenesis; membrane fraction; 01 06 MNT3 O-linked glycosylation; 01 06 MNT2 O-linked glycosylation; 01 06 MNN1 N-glycan processing; O-linked glycosylation; Golgi apparatus; 01 06 TEX1 mRNA-nucleus export; transcription export complex; YNL116W ERP6 secretory pathway; integral to membrane; 08 06 ECM5 cell wall organization and biogenesis; AVT2 transport; endoplasmic reticulum; PRP11 spliceosome assembly; snRNP U2; 04 SOL2 tRNA processing; 04 CUS2 nuclear mRNA splicing\, via spliceosome; snRNP U2; 04 BYE1 04 DBP6 ribosomal large subunit assembly and maintenance; 35S primary transcript processing; nucleolus; 04 06 YER066W 03 TRF5 sister chromatid cohesion; nucleus; 03 ATO3 transport; nitrogen utilization; membrane; 01 08 PAC1 nuclear migration (sensu Saccharomyces); nuclear migration (sensu Fungi); cytoplasm; cytoplasmic microtubule; YGR210C LST8 transport; signal transduction; Golgi membrane; peripheral to membrane of membrane fraction; endosome membrane; 08 YLR324W SAP185 G1/S transition of mitotic cell cycle; cytoplasm; 03 14 STE13 peptide pheromone maturation; Golgi apparatus; Golgi trans face; 14 06 TPO4 polyamine transport; vacuolar membrane; plasma membrane; 11 YMR009W CIT3 tricarboxylic acid cycle; citrate metabolism; propionate metabolism; mitochondrial matrix; 01 02 CRH1 incipient bud site; cell wall (sensu Fungi); YOR378W 11 YKL069W YIR042C MET12 methionine metabolism; cell; 01 HOL1 transport; plasma membrane; 11 ERV2 protein thiol-disulfide exchange; microsome; TPO2 polyamine transport; vacuolar membrane; plasma membrane; 11 PXL1 PFY1 response to osmotic stress; axial budding; polar budding; actin polymerization and/or depolymerization; contractile ring (sensu Saccharomyces); actin cap (sensu Saccharomyces); 14 OAF1 fatty acid metabolism; peroxisome organization and biogenesis; positive regulation of transcription; nucleus; 01 04 SCO1 protein complex assembly; copper ion transport; mitochondrial inner membrane; 13 06 PCH2 regulation of meiosis; nucleolus; 03 PAN1 actin cortical patch assembly; cytokinesis; endocytosis; axial budding; polar budding; actin cortical patch (sensu Saccharomyces); plasma membrane; 06 08 14 YGL245W 05 SPC2 signal peptide processing; signal peptidase complex; 06 TFC6 transcription initiation from Pol III promoter; transcription factor TFIIIC complex; 04 MTH1 signal transduction; glucose transport; 01 GFD2 IVY1 secretory pathway; vacuolar membrane (sensu Fungi); 08 RVS161 endocytosis; response to osmotic stress; polar budding; actin cortical patch (sensu Saccharomyces); lipid raft; 14 08 SLA2 exocytosis; endocytosis; actin filament organization; cell wall organization and biogenesis; polar budding; incipient bud site; actin cortical patch (sensu Saccharomyces); 14 01 06 08 COF1 actin filament organization; actin filament depolymerization; actin cortical patch (sensu Saccharomyces); 06 14 08 YSC84 endocytosis; actin filament organization; actin cortical patch (sensu Saccharomyces); 14 LSB3 LSB1 cytoplasm; 10 MYO5 exocytosis; endocytosis; response to osmotic stress; cell wall organization and biogenesis; polar budding; salinity response; actin cortical patch (sensu Saccharomyces); 14 08 LSB5 endocytosis; actin filament organization; cell cortex; VRP1 endocytosis; response to osmotic stress; actin filament organization; polar budding; actin cortical patch (sensu Saccharomyces); 14 08 BZZ1 actin filament organization; salinity response; cytoplasm; actin cortical patch (sensu Saccharomyces); MYO3 exocytosis; endocytosis; response to osmotic stress; cell wall organization and biogenesis; polar budding; actin cortical patch (sensu Saccharomyces); 08 14 YDR063W ARC15 actin cortical patch assembly; mitochondrial membrane; Arp2/3 protein complex; 08 ARP2 actin filament organization; mitochondrion; Arp2/3 protein complex; 14 08 03 ARC40 actin filament organization; Arp2/3 protein complex; 14 ARP3 actin filament organization; Arp2/3 protein complex; 08 ARC19 actin cortical patch assembly; Arp2/3 protein complex; 08 RVS167 endocytosis; response to osmotic stress; polar budding; actin cortical patch (sensu Saccharomyces); 14 SAC6 endocytosis; response to osmotic stress; actin filament organization; polar budding; actin cable (sensu Saccharomyces); actin cortical patch (sensu Saccharomyces); 14 08 RSP5 protein polyubiquitination; chromatin assembly/disassembly; protein monoubiquitination; ubiquitin ligase complex; 14 06 11 ABP1 actin cortical patch assembly; establishment of cell polarity (sensu Saccharomyces); cytoplasm; cytoskeleton; cell cortex; 14 ACT1 mitochondrion inheritance; vacuole inheritance; mitotic spindle orientation; establishment of cell polarity (sensu Saccharomyces); cytokinesis; regulation of transcription from Pol II promoter; exocytosis; endocytosis; response to osmotic stress; cell wall organization and biogenesis; apical bud growth; isotropic bud growth; sporulation (sensu Saccharomyces); protein secretion; histone acetylation; cell cycle dependent actin filament reorganization; vesicle transport along actin filament; histone acetyltransferase complex; actin cable (sensu Saccharomyces); contractile ring (sensu Saccharomyces); actin cortical patch (sensu Saccharomyces); actin filament; 03 14 08 SLA1 actin cortical patch assembly; endocytosis; actin filament organization; cell wall organization and biogenesis; polar budding; actin cortical patch (sensu Saccharomyces); 14 06 HUA1 cytoplasm; 14 BBC1 actin cytoskeleton organization and biogenesis; actin cortical patch (sensu Saccharomyces); CAP2 endocytosis; response to osmotic stress; actin filament organization; cell wall organization and biogenesis; actin cortical patch (sensu Saccharomyces); F-actin capping protein complex; 14 APP1 actin cytoskeleton organization and biogenesis; actin cortical patch (sensu Saccharomyces); actin cytoskeleton; 14 ABZ1 para-aminobenzoic acid metabolism; 01 YIL108W APP2 LAS17 cytokinesis; endocytosis; response to osmotic stress; actin filament organization; polar budding; actin polymerization and/or depolymerization; cytoplasm; actin cortical patch (sensu Saccharomyces); 03 14 06 PEX25 peroxisome organization and biogenesis; peroxisomal membrane; MNN9 N-linked glycosylation; mannosyltransferase complex; Golgi cis-face; membrane; 06 01 MCA1 apoptosis; nucleus; 14 MNN11 protein amino acid glycosylation; mannosyltransferase complex; 06 MNN10 cell wall mannoprotein biosynthesis; mannan metabolism; N-glycan processing; actin filament organization; mannosyltransferase complex; 06 14 01 ANP1 N-linked glycosylation; mannosyltransferase complex; Golgi cis cisterna; 06 YMR130W RHO3 establishment of cell polarity (sensu Saccharomyces); exocytosis; actin filament organization; small GTPase mediated signal transduction; intracellular; 14 YMR221C MNN4 N-linked glycosylation; O-linked glycosylation; response to stress; 06 HOC1 cell wall mannoprotein biosynthesis; mannan metabolism; N-glycan processing; mannosyltransferase complex; 01 06 14 VAN1 N-linked glycosylation; mannosyltransferase complex; Golgi cis-face; membrane; 03 14 06 GRC3 rRNA processing; cell growth and/or maintenance; HOM2 methionine metabolism; threonine metabolism; homoserine biosynthesis; 01 ARC18 actin filament organization; Arp2/3 protein complex; 08 YMR084W STT4 MAPKKK cascade; phosphatidylethanolamine biosynthesis; protein secretion; actin cytoskeleton organization and biogenesis; plasma membrane; 01 10 03 YLR415C PIK1 cytokinesis; post-Golgi transport; signal transduction; nucleus; Golgi apparatus; 03 01 10 ASI2 ubiquitin-dependent protein catabolism; integral to membrane; YNL033W YNL018C YMR244W 02 PET309 protein biosynthesis; aerobic respiration; RNA metabolism; mitochondrial inner membrane; integral to membrane; 05 04 FMS1 polyamine catabolism; pantothenate biosynthesis; cytoplasm; 01 SPS19 sporulation (sensu Saccharomyces); fatty acid catabolism; peroxisomal matrix; 02 PEX22 protein-peroxisome targeting; peroxisome; 08 REC114 meiotic recombination; meiotic DNA double-strand break formation; 03 GAT2 transcription; nucleus; ECM30 cell wall organization and biogenesis; YML020W MTG1 protein biosynthesis; ribosome assembly; mitochondrial inner membrane; GON3 YDR124W HUL4 protein polyubiquitination; protein monoubiquitination; 04 YHR022C YGL138C YBR285W XYL2 monosaccharide metabolism; 01 LSB6 actin filament organization; membrane fraction; cytoplasm; vacuolar membrane; plasma membrane; FSP2 01 02 YGR068C YKR105C 11 YGR053C YGR058W YER071C YDL129W cytoplasm; EGD2 nascent polypeptide association; nascent polypeptide-associated complex; 01 04 BTT1 nascent polypeptide association; nascent polypeptide-associated complex; 04 ### CLUSTER 9 ### 00 Not clear CYM1 HPR1 DNA recombination; RNA elongation from Pol II promoter; mRNA-nucleus export; THO complex; 03 04 THP2 DNA recombination; RNA elongation from Pol II promoter; mRNA-nucleus export; THO complex; MFT1 DNA recombination; RNA elongation from Pol II promoter; mRNA-nucleus export; THO complex; 06 08 GPI17 attachment of GPI anchor to protein; integral to endoplasmic reticulum membrane; ### CLUSTER 10 ### 01 Metabolism OST5 N-linked glycosylation; oligosaccharyl transferase complex; 01 06 OST1 N-linked glycosylation; N-linked glycosylation via asparagine; endoplasmic reticulum lumen; oligosaccharyl transferase complex; 01 06 WBP1 N-linked glycosylation; cell cycle; nuclear membrane; endoplasmic reticulum; oligosaccharyl transferase complex; 01 06 STT3 N-linked glycosylation; oligosaccharyl transferase complex; 01 06 OST4 N-linked glycosylation; endoplasmic reticulum membrane; 01 06 SWP1 N-linked glycosylation; oligosaccharyl transferase complex; 01 06 OST3 protein complex assembly; protein amino acid glycosylation; N-linked glycosylation; oligosaccharyl transferase complex; integral to membrane; 06 01 YLR021W ### CLUSTER 11 ### 00 Not clear SPC1 signal peptide processing; signal peptidase complex; 06 ATF2 steroid metabolism; cytoplasm; 01 ### CLUSTER 12 ### 00 Not clear SOY1 cytoplasm; YBR220C NFS1 iron ion homeostasis; iron-sulfur cluster assembly; mitochondrion; 13 ### CLUSTER 13 ### 04 Transcription/RNA processing/RNA transport SEN34 tRNA splicing; tRNA-intron endonuclease complex; nuclear inner membrane; 04 SEN2 tRNA splicing; tRNA-intron endonuclease complex; nuclear inner membrane; 04 SEN15 tRNA splicing; tRNA-intron endonuclease complex; nuclear inner membrane; 04 ### CLUSTER 14 ### 08 Cellular transport SWA2 ER organization and biogenesis; endoplasmic reticulum membrane; 08 CLC1 vesicle-mediated transport; clathrin vesicle coat; 14 08 CHC1 vesicle-mediated transport; clathrin vesicle coat; 08 06 APM2 vesicle-mediated transport; AP-1 adaptor complex; 08 YFR043C APL2 vesicle-mediated transport; AP-1 adaptor complex; 06 08 KRE5 beta-1\,6 glucan biosynthesis; endoplasmic reticulum; 01 14 APS1 vesicle-mediated transport; AP-1 adaptor complex; 06 08 ### CLUSTER 15 ### 06 Protein fate FAT1 very-long-chain fatty acid metabolism; lipid transport; peroxisome; microsome; lipid particle; plasma membrane; 01 NMT1 N-terminal peptidyl-glycine N-myristoylation; cytosol; 01 06 FAA3 N-terminal protein myristoylation; lipid metabolism; 01 BSC2 ZRC1 glutathione metabolism; cobalt ion transport; zinc ion transport; zinc ion homeostasis; vacuole (sensu Fungi); 11 13 08 SPS4 DNA metabolism; meiosis; sporulation (sensu Saccharomyces); 14 YOR093C CPR8 06 FAA4 N-terminal protein myristoylation; lipid metabolism; lipid transport; cytoplasm; lipid particle; 01 06 YHB1 response to stress; 11 CBP2 Group I intron splicing; mitochondrion; 04 YLR199C YDR117C 08 06 ERV46 ER to Golgi transport; COPII-coated vesicle; integral to Golgi membrane; integral to endoplasmic reticulum membrane; 08 GWT1 GPI anchor biosynthesis; membrane; YFR042W LHS1 response to unfolded protein; protein transport; endoplasmic reticulum lumen; 06 RPN4 ubiquitin-dependent protein catabolism; proteasome regulatory particle (sensu Eukarya); 06 14 YDL193W endoplasmic reticulum; lipid particle; GPX2 response to oxidative stress; 11 POM34 nucleocytoplasmic transport; nuclear pore; 08 ### CLUSTER 16 ### 04 Transcription/RNA processing/RNA transport GAT4 transcription; nucleus; GAT3 transcription; nucleus; 04 01 ARP8 nucleus; MUD2 U2-type nuclear mRNA branch site recognition; commitment complex; 04 SYP1 bud tip; bud neck; shmoo tip; YOR338W ATP18 ATP synthesis coupled proton transport; proton-transporting ATP synthase complex\, coupling factor F(o) (sensu Eukarya); 02 ATP2 age dependent general metabolic decline during replicative cell aging; ATP synthesis coupled proton transport; soluble fraction; proton-transporting ATP synthase\, catalytic core (sensu Eukarya); 02 13 08 ATP17 ATP synthesis coupled proton transport; proton-transporting ATP synthase complex\, coupling factor F(o) (sensu Eukarya); 02 06 ATP3 ATP synthesis coupled proton transport; proton-transporting ATP synthase\, central stalk (sensu Eukarya); 13 02 08 TIM11 ATP synthesis coupled proton transport; proton-transporting ATP synthase complex\, coupling factor F(o) (sensu Eukarya); 02 08 06 INH1 ATP synthesis coupled proton transport; proton-transporting ATP synthase complex (sensu Eukarya); 02 ATP5 ATP synthesis coupled proton transport; proton-transporting ATP synthase\, stator stalk (sensu Eukarya); 02 13 08 ATP1 ATP synthesis coupled proton transport; proton-transporting ATP synthase\, catalytic core (sensu Eukarya); 13 08 02 YDR071C DCP2 deadenylation-dependent decapping; mRNA catabolism; cytoplasmic mRNA processing body; nucleus; cytoplasm; 02 RIM20 proteolysis and peptidolysis; invasive growth; protein processing; sporulation; POP2 poly(A) tail shortening; regulation of transcription from Pol II promoter; cytoplasm; CCR4-NOT core complex; 01 14 04 SPC3 signal peptide processing; signal peptidase complex; 06 UPC2 steroid metabolism; sterol biosynthesis; nucleus; cytoplasm; 01 04 AAR2 assembly of spliceosomal tri-snRNP; snRNP U5; 04 YGR021W PRP9 nuclear mRNA splicing\, via spliceosome; snRNP U2; 04 PRP5 U2-type nuclear mRNA branch site recognition; spliceosome complex; 04 06 SPP381 nuclear mRNA splicing\, via spliceosome; spliceosome complex; 04 SNU56 nuclear mRNA splicing\, via spliceosome; commitment complex; snRNP U1; 04 LUC7 mRNA splice site selection; snRNP U1; 04 MUD1 nuclear mRNA splicing\, via spliceosome; snRNP U1; 04 SNU71 nuclear mRNA splicing\, via spliceosome; commitment complex; snRNP U1; 04 NAM8 nuclear mRNA splicing\, via spliceosome; mRNA splice site selection; commitment complex; snRNP U1; 03 04 SMD1 nuclear mRNA splicing\, via spliceosome; commitment complex; small nuclear ribonucleoprotein complex; 04 06 PRP38 nuclear mRNA splicing\, via spliceosome; small nuclear ribonucleoprotein complex; 04 SMX2 nuclear mRNA splicing\, via spliceosome; small nuclear ribonucleoprotein complex; 04 SMB1 nuclear mRNA splicing\, via spliceosome; small nuclear ribonucleoprotein complex; 04 PAT1 regulation of translational initiation; chromosome segregation; cytoplasmic mRNA processing body; cytosolic small ribosomal subunit (sensu Eukarya); 03 04 LSM2 nuclear mRNA splicing\, via spliceosome; rRNA processing; small nuclear ribonucleoprotein complex; 04 LSM5 nuclear mRNA splicing\, via spliceosome; rRNA processing; small nuclear ribonucleoprotein complex; 04 LSM6 nuclear mRNA splicing\, via spliceosome; small nuclear ribonucleoprotein complex; 04 LSM4 nuclear mRNA splicing\, via spliceosome; rRNA processing; small nuclear ribonucleoprotein complex; 04 LSM1 mRNA catabolism\, deadenylation-dependent; deadenylation-dependent decapping; rRNA processing; cytoplasmic mRNA processing body; mRNA cap complex; 04 PRP24 assembly of spliceosomal tri-snRNP; spliceosome assembly; spliceosome complex; 04 PRP2 U2-type catalytic spliceosome formation for 1st transesterification step; nucleus; spliceosome complex; 04 LSM7 nuclear mRNA splicing\, via spliceosome; mRNA catabolism; snRNP U6; 04 ILM1 LSM8 nuclear mRNA splicing\, via spliceosome; rRNA processing; nucleus; small nuclear ribonucleoprotein complex; 04 LSM3 nuclear mRNA splicing\, via spliceosome; rRNA processing; snRNP U6; 04 PRP8 nuclear mRNA splicing\, via spliceosome; snRNP U5; small nuclear ribonucleoprotein complex; 04 03 BRR2 U2-type spliceosome conformational change to release U4 and U1; snRNP U5; U4/U6 x U5 tri-snRNP complex; 04 PRP6 nuclear mRNA splicing\, via spliceosome; small nuclear ribonucleoprotein complex; 04 PRP3 nuclear mRNA splicing\, via spliceosome; small nuclear ribonucleoprotein complex; 04 06 SNU114 nuclear mRNA splicing\, via spliceosome; snRNP U5; snRNP U4; snRNP U6; 05 PRP31 nuclear mRNA splicing\, via spliceosome; small nuclear ribonucleoprotein complex; 04 SNU23 nuclear mRNA splicing\, via spliceosome; small nuclear ribonucleoprotein complex; 04 KEM1 35S primary transcript processing; mRNA catabolism; filamentous growth; cytoplasmic mRNA processing body; cytoplasm; 03 01 04 HSH155 spliceosome assembly; snRNP U2; 04 CWC2 nuclear mRNA splicing\, via spliceosome; spliceosome complex; 04 SMD3 nuclear mRNA splicing\, via spliceosome; commitment complex; small nuclear ribonucleoprotein complex; 04 SMD2 nuclear mRNA splicing\, via spliceosome; small nuclear ribonucleoprotein complex; 04 MSL1 nuclear mRNA splicing\, via spliceosome; snRNP U2; 04 06 SHM2 one-carbon compound metabolism; cytoplasm; 01 PRP40 nuclear mRNA splicing\, via spliceosome; commitment complex; snRNP U1; 04 PRP46 nuclear mRNA splicing\, via spliceosome; spliceosome complex; MBF1 positive regulation of transcription from Pol II promoter; nucleus; 04 YDR357C PRP39 nuclear mRNA splicing\, via spliceosome; commitment complex; snRNP U1; 04 YLR424W YKT9 08 CSN12 adaptation to pheromone during conjugation with cellular fusion; signalosome complex; CAF4 regulation of transcription\, DNA-dependent; CCR4-NOT complex; 04 SME1 nuclear mRNA splicing\, via spliceosome; small nuclear ribonucleoprotein complex; 04 PRP42 nuclear mRNA splicing\, via spliceosome; commitment complex; snRNP U1; 04 RSE1 spliceosome assembly; nuclear mRNA splicing\, via spliceosome; snRNP U2; 04 08 HRP1 mRNA polyadenylation; mRNA cleavage; nucleus; mRNA cleavage factor complex; 04 CUS1 spliceosome assembly; snRNP U2; 04 PRP16 formation of catalytic U2-type spliceosome for 2nd transesterification step; spliceosome complex; 04 PRP28 cis assembly of U2-type pre-catalytic spliceosome; spliceosome complex; 04 PRP18 nuclear mRNA splicing\, via spliceosome; spliceosome complex; 04 PRP22 U2-type spliceosome dissembly; spliceosome complex; 04 SLU7 nuclear mRNA splicing\, via spliceosome; spliceosome complex; 04 CWC23 spliceosome complex; 04 11 CDC40 mitotic spindle assembly (sensu Saccharomyces); S phase of mitotic cell cycle; nuclear mRNA splicing\, via spliceosome; DNA replication; nuclear membrane; nuclear pore; spliceosome complex; 03 GID7 negative regulation of gluconeogenesis; PRP19 nuclear mRNA splicing\, via spliceosome; nucleus; spliceosome complex; cytoplasm; 04 CLF1 nuclear mRNA splicing\, via spliceosome; cell cycle; RNA splicing; spliceosome complex; 04 03 CEF1 nuclear mRNA splicing\, via spliceosome; spliceosome complex; 03 ISY1 nuclear mRNA splicing\, via spliceosome; spliceosome complex; 04 ECM2 cell wall organization and biogenesis; SYF2 nuclear mRNA splicing\, via spliceosome; cell cycle; spliceosome complex; 04 SYF1 nuclear mRNA splicing\, via spliceosome; cell cycle; spliceosome complex; 04 03 NTC20 nuclear mRNA splicing\, via spliceosome; spliceosome complex; 04 YJU2 YKR022C CMK2 protein amino acid phosphorylation; signal transduction; 10 CTK1 regulation of transcription from Pol II promoter; protein amino acid phosphorylation; nucleus; 04 YCR061W SET5 ### CLUSTER 17 ### 01 Metabolism PIR3 cell wall organization and biogenesis; cell wall (sensu Fungi); 11 PIR1 intracellular protein transport; cell wall organization and biogenesis; cell wall (sensu Fungi); 11 AMN1 negative regulation of exit from mitosis; mitotic checkpoint; nucleus; cytoplasm; bud; ASH1 pseudohyphal growth; regulation of transcription\, mating-type specific; nucleus; 14 04 13 NIS1 regulation of mitosis; nucleus; bud neck; 03 CTS1 cytokinesis\, completion of separation; extracellular; nuclear membrane; endoplasmic reticulum; cell wall (sensu Fungi); 01 03 DSE1 cell wall organization and biogenesis; 14 CSM1 meiotic chromosome segregation; meiosis I\, chromosome segregation; nuclear chromosome; nuclear membrane; nucleolus; 14 03 VRG4 N-linked glycosylation; nucleotide-sugar transport; lipid glycosylation; Golgi apparatus; 08 ARD1 protein amino acid acetylation; cytoplasm; 01 06 03 PAD1 aromatic compound catabolism; 11 FUN26 nucleoside transport; intracellular; membrane; 01 RGD1 osmosensory signaling pathway; actin cortical patch (sensu Saccharomyces); bud; 10 MAK31 N-terminal protein amino acid acetylation; virus-host interaction; MAK10 N-terminal protein amino acid acetylation; virus-host interaction; 02 TEL2 telomerase-dependent telomere maintenance; nuclear telomere cap complex; NAT1 protein amino acid acetylation; intracellular; cytoplasm; 01 05 06 SIR2 chromatin silencing at ribosomal DNA (rDNA); loss of chromatin silencing during replicative cell aging; double-strand break repair via nonhomologous end-joining; chromatin assembly/disassembly; chromatin silencing at HML and HMR (sensu Saccharomyces); chromatin silencing at telomere; nuclear telomere cap complex; nuclear telomeric heterochromatin; nucleolus; 14 03 06 04 SIR4 loss of chromatin silencing during replicative cell aging; double-strand break repair via nonhomologous end-joining; chromatin silencing; nuclear telomere cap complex; nuclear telomeric heterochromatin; 14 03 04 11 SIR1 establishment of chromatin silencing; chromatin silencing at HML and HMR (sensu Saccharomyces); chromatin silencing complex; 14 04 SIR3 loss of chromatin silencing during replicative cell aging; double-strand break repair via nonhomologous end-joining; chromatin silencing; nuclear telomere cap complex; nuclear telomeric heterochromatin; nucleolus; 04 03 14 RIF2 telomerase-dependent telomere maintenance; nuclear telomere cap complex; RIF1 chromatin silencing at telomere; telomerase-dependent telomere maintenance; nuclear telomere cap complex; 04 ABF1 DNA replication; chromatin silencing at HML and HMR (sensu Saccharomyces); positive regulation of transcription; nuclear chromatin; 01 03 04 DSE4 cytokinesis\, completion of separation; extracellular; septum; 01 RAP1 chromatin silencing; chromatin silencing at telomere; transcription from Pol III promoter; telomerase-dependent telomere maintenance; nuclear telomere cap complex; nucleus; nuclear telomeric heterochromatin; 04 01 03 05 GCR2 positive regulation of glycolysis; positive regulation of transcription from Pol II promoter; nucleus; 01 04 EGT2 cytokinesis; cell wall (sensu Fungi); 03 14 SCW11 cytokinesis\, completion of separation; cell wall (sensu Fungi); DSE2 cell wall organization and biogenesis; cytokinesis\, completion of separation; extracellular; cell wall (sensu Fungi); 03 PST1 cell wall (sensu Fungi); 14 03 HNT1 nucleotide metabolism; cytoplasm; 01 ORC5 pre-replicative complex formation and maintenance; DNA replication initiation; chromatin silencing at HML and HMR (sensu Saccharomyces); nuclear origin of replication recognition complex; 14 03 04 ORC1 pre-replicative complex formation and maintenance; DNA replication initiation; chromatin silencing at HML and HMR (sensu Saccharomyces); nuclear origin of replication recognition complex; 14 04 03 ORC3 pre-replicative complex formation and maintenance; DNA replication initiation; chromatin silencing at HML and HMR (sensu Saccharomyces); nuclear origin of replication recognition complex; 14 04 03 CDC6 pre-replicative complex formation and maintenance; pre-replicative complex; 03 ORC6 pre-replicative complex formation and maintenance; DNA replication initiation; chromatin silencing at HML and HMR (sensu Saccharomyces); nuclear origin of replication recognition complex; 03 14 04 ORC2 pre-replicative complex formation and maintenance; DNA replication initiation; chromatin silencing at HML and HMR (sensu Saccharomyces); nuclear origin of replication recognition complex; 14 03 04 YIL056W MSC3 meiotic recombination; RGA1 establishment of cell polarity (sensu Saccharomyces); signal transduction during conjugation with cellular fusion; actin filament organization; apical bud growth; isotropic bud growth; pseudohyphal growth; invasive growth; small GTPase mediated signal transduction; intracellular; 14 BIT89 YOL070C YKL105C SPC105 microtubule nucleation; spindle pole body; YMR086W cytoplasm; ESC1 chromatin silencing at telomere; nucleus; 04 HXT7 hexose transport; plasma membrane; 01 08 HXT6 hexose transport; plasma membrane; 01 08 HXT1 hexose transport; plasma membrane; 01 08 GAL2 galactose metabolism; extracellular carbohydrate transport; plasma membrane; 01 08 ITR1 myo-inositol transport; membrane; 01 08 SNF3 signal transduction; response to glucose stimulus; plasma membrane; 01 13 08 HXT4 hexose transport; plasma membrane; 01 08 HXT3 hexose transport; plasma membrane; 01 08 HXT10 hexose transport; plasma membrane; 01 08 ### CLUSTER 18 ### 01 Metabolism LPD1 acetyl-CoA biosynthesis from pyruvate; glycine catabolism; isoleucine catabolism; leucine catabolism; L-serine biosynthesis; valine catabolism; mitochondrial matrix; pyruvate dehydrogenase complex (sensu Eukarya); 01 02 KGD2 tricarboxylic acid cycle; 2-oxoglutarate metabolism; mitochondrial matrix; 02 01 PDB1 pyruvate metabolism; mitochondrion; pyruvate dehydrogenase complex; 02 01 VTC1 vacuole fusion (non-autophagic); vacuolar membrane; 14 SPF1 protein amino acid glycosylation; calcium ion homeostasis; endoplasmic reticulum membrane; 13 AFG1 SUR2 sphingolipid metabolism; sphingolipid biosynthesis; endoplasmic reticulum; 01 GUP1 glycerol transport; glycerol catabolism; membrane; CDC19 pyruvate metabolism; glycolysis; cytosol; 01 02 APE3 vacuolar protein catabolism; vacuole (sensu Fungi); 06 TDH1 gluconeogenesis; glycolysis; lipid particle; cytosol; cell wall (sensu Fungi); 02 01 SEC11 signal peptide processing; endoplasmic reticulum; signal peptidase complex; 06 TPI1 gluconeogenesis; glycolysis; cytoplasm; cytosol; 01 02 TDH3 gluconeogenesis; glycolysis; cytoplasm; lipid particle; cytosol; cell wall (sensu Fungi); 02 01 ENO2 gluconeogenesis; glycolysis; phosphopyruvate hydratase complex; soluble fraction; 02 01 ENO1 gluconeogenesis; glycolysis; phosphopyruvate hydratase complex; cytoplasm; 02 01 YHR080C SNT2 SPT10 chromatin modeling; regulation of global transcription from Pol II promoter; nucleus; 04 YLR053C PGK1 gluconeogenesis; glycolysis; cytoplasm; cytosol; 02 01 ADH4 fermentation; 01 02 ADH3 fermentation; soluble fraction; mitochondrial matrix; 01 TUB1 nuclear migration (sensu Saccharomyces); mitotic chromosome segregation; nuclear migration during conjugation with cellular fusion; homologous chromosome segregation; spindle pole body; polar microtubule; kinetochore microtubule; nuclear microtubule; cytoplasmic microtubule; 03 FBA1 gluconeogenesis; glycolysis; cytoplasm; cytosol; 02 01 ADH2 ethanol metabolism; fermentation; cytoplasm; 02 01 UBP14 protein deubiquitination; negative regulation of gluconeogenesis; cytoplasm; 06 POR1 ion transport; mitochondrion organization and biogenesis; aerobic respiration; mitochondrial outer membrane; 08 GPM1 gluconeogenesis; glycolysis; cytosol; 01 02 YML082W sulfur metabolism; 01 HOM6 methionine metabolism; threonine metabolism; homoserine biosynthesis; 01 CCT5 protein folding; cytoskeleton organization and biogenesis; cytoplasm; cytoskeleton; 06 YBL046W PPH3 protein amino acid dephosphorylation; nitrogen metabolism; 14 YDL109C lipid metabolism; 01 HOS2 establishment and/or maintenance of chromatin architecture; regulation of transcription\, DNA-dependent; histone deacetylation; negative regulation of meiosis; histone deacetylase complex; 03 06 SNT1 histone deacetylation; negative regulation of meiosis; histone deacetylase complex; 06 SIF2 negative regulation of transcription from Pol II promoter; chromatin silencing at telomere; histone deacetylation; negative regulation of meiosis; histone deacetylase complex; nucleus; 11 04 CPR1 protein metabolism; histone deacetylase complex; 11 06 HST4 chromatin silencing at telomere; short-chain fatty acid metabolism; 04 14 SUM1 chromatin silencing at HML and HMR (sensu Saccharomyces); chromatin silencing at telomere; regulation of mitosis; histone deacetylase complex; nucleus; 04 HST1 transcriptional gene silencing; histone deacetylase complex; nucleus; 14 04 SET3 histone deacetylation; negative regulation of meiosis; histone deacetylase complex; TRS120 ER to Golgi transport; TRAPP; 08 TRS23 ER to Golgi transport; TRAPP; 08 TRS20 ER to Golgi transport; TRAPP; 08 TRS31 ER to Golgi transport; TRAPP; 08 GSG1 ER to Golgi transport; meiosis; TRAPP; 14 08 03 ### CLUSTER 19 ### 01 Metabolism MTR3 35S primary transcript processing; mRNA catabolism; nuclear exosome (RNase complex); cytoplasmic exosome (RNase complex); 04 RRP42 35S primary transcript processing; mRNA catabolism; nuclear exosome (RNase complex); cytoplasmic exosome (RNase complex); 04 RRP46 35S primary transcript processing; mRNA catabolism; nuclear exosome (RNase complex); cytoplasmic exosome (RNase complex); 04 RRP45 35S primary transcript processing; mRNA catabolism; nuclear exosome (RNase complex); cytoplasmic exosome (RNase complex); 04 SKI6 35S primary transcript processing; mRNA catabolism; nuclear exosome (RNase complex); cytoplasmic exosome (RNase complex); 04 01 RRP43 35S primary transcript processing; mRNA catabolism; nuclear exosome (RNase complex); cytoplasmic exosome (RNase complex); 04 UAF30 transcription from Pol I promoter; RNA polymerase I upstream activating factor complex; 04 SKI8 mRNA catabolism; cytoplasm; 03 11 SKI2 mRNA catabolism; regulation of translation; cytoplasm; 11 FYV4 MAS2 mitochondrial processing; mitochondrial processing peptidase complex; 06 SSD1 cell wall organization and biogenesis; cytoplasm; 14 11 03 RRP4 35S primary transcript processing; mRNA catabolism; nuclear exosome (RNase complex); cytoplasmic exosome (RNase complex); 04 YMR181C NKP2 YDR506C 13 SOH1 DNA repair; transcription from Pol II promoter; 03 04 NUT1 regulation of transcription from Pol II promoter; nucleus; 04 ADE8 adenine biosynthesis; 01 ADE1 purine base metabolism; 01 ADE5,7 purine base metabolism; cytoplasm; 01 EAF5 ADE3 purine base biosynthesis; cytoplasm; 01 04 ADE6 purine nucleotide biosynthesis; 01 ADE4 purine base metabolism; 01 SUL1 sulfate transport; plasma membrane; 13 01 08 LYS5 protein-cofactor linkage; lysine biosynthesis\, aminoadipic pathway; cytoplasm; 01 RAD6 DNA repair; ubiquitin-dependent protein catabolism; protein monoubiquitination; histone ubiquitination; proteasome complex (sensu Eukarya); nucleus; cytoplasm; 03 04 06 14 RAD18 DNA repair; nuclear chromatin; 03 06 YHR045W TAF9 G1-specific transcription in mitotic cell cycle; establishment and/or maintenance of chromatin architecture; transcription initiation from Pol II promoter; protein amino acid acetylation; chromatin modification; histone acetylation; SAGA complex; transcription factor TFIID complex; 04 HFA1 01 ARG3 arginine biosynthesis; ornithine metabolism; cytosol; 01 TRP2 tryptophan biosynthesis; 01 ARG1 citrulline metabolism; argininosuccinate metabolism; arginine biosynthesis; cytosol; 01 YCL073C transport; membrane; 11 YER034W CPA2 arginine biosynthesis; cytosol; 01 TRP4 tryptophan biosynthesis; 01 ARG2 arginine biosynthesis; ornithine biosynthesis; mitochondrial matrix; 01 YJL068C formaldehyde catabolism; cytosol; 01 ARG5,6 arginine biosynthesis; ornithine biosynthesis; mitochondrial matrix; 01 HIS4 histidine biosynthesis; cell; 01 TRP5 tryptophan biosynthesis; cytoplasm; 01 YGL117W ARO3 aromatic amino acid family biosynthesis; 01 TRP1 tryptophan biosynthesis; amino acid metabolism; cytoplasm; 01 LEU2 leucine biosynthesis; cytosol; 01 HIS1 histidine biosynthesis; cell; 01 ADE2 purine base metabolism; 01 HIS5 histidine biosynthesis; cell; 01 ARG4 arginine biosynthesis; cytosol; 01 URA3 pyrimidine base biosynthesis; 01 URA1 pyrimidine base biosynthesis; cytoplasm; 01 URA2 pyrimidine base biosynthesis; cytoplasm; 01 TRP3 tryptophan biosynthesis; 01 FZF1 sulfite transport; positive regulation of transcription from Pol II promoter; nucleus; 01 11 04 HIS7 histidine biosynthesis; cell; 01 YSC83 ASN2 asparagine biosynthesis; 01 SSQ1 DNA dependent DNA replication; intracellular iron ion storage; mitochondrial matrix; 03 13 11 06 LYS20 lysine biosynthesis\, aminoadipic pathway; nucleus; 01 LYS2 lysine biosynthesis\, aminoadipic pathway; cytoplasm; 01 PHO2 histidine biosynthesis; transcription; purine base biosynthesis; cellular response to phosphate starvation; nucleus; 01 04 UBR2 protein polyubiquitination; protein monoubiquitination; EXG2 cell wall (sensu Fungi); 01 14 ILV6 branched chain family amino acid biosynthesis; mitochondrion; 01 LEU1 leucine biosynthesis; cytosol; 01 ILV5 mitochondrial genome maintenance; branched chain family amino acid biosynthesis; mitochondrion; 01 HYM1 cytokinesis\, completion of separation; regulation of cell shape; intracellular; 14 ASG7 conjugation with cellular fusion; plasma membrane; 14 PRM2 conjugation with cellular fusion; integral to membrane; FIG1 cellular morphogenesis during conjugation with cellular fusion; cytogamy; shmoo tip; cell wall (sensu Fungi); 14 HIT1 aerobic respiration; 11 ### CLUSTER 20 ### 00 Not clear GNA1 UDP-N-acetylglucosamine biosynthesis; 03 YDL157C YBR269C YHR083W YCR095C MRPL20 mitochondrial genome maintenance; protein biosynthesis; mitochondrial large ribosomal subunit; 05 YNL056W SIW14 protein amino acid dephosphorylation; response to stress; ### CLUSTER 21 ### 13 Regulation/Integration with environment PMP2 cation transport; membrane; 13 PMP1 cation transport; plasma membrane; membrane; 13 YRO2 11 ### CLUSTER 22 ### 05 Protein synthesis PET54 Group I intron splicing; protein biosynthesis; mitochondrial inner membrane; mitochondrial matrix; 04 05 MSK1 lysyl-tRNA aminoacylation; mitochondrion; 05 PET122 protein biosynthesis; mitochondrial inner membrane; 05 ### CLUSTER 23 ### 13 Regulation/Integration with environment MND2 meiotic recombination; regulation of mitotic metaphase/anaphase transition; anaphase-promoting complex; FRE7 13 ### CLUSTER 24 ### 03 Cell cycle & DNA processing POL4 base-excision repair\, gap-filling; double-strand break repair; nucleus; 03 LIF1 double-strand break repair via nonhomologous end-joining; nucleus; 03 14 ABZ2 ### CLUSTER 25 ### 00 Not clear COX1 aerobic respiration; respiratory chain complex IV (sensu Eukarya); 02 AI4 RNA splicing; mitochondrion; 04 ### CLUSTER 26 ### 11 Cell rescue/Defense YBR293W 11 SIT1 iron ion homeostasis; iron-siderochrome transport; endosome; cytoplasmic vesicle; 11 FIT1 siderochrome transport; cell wall (sensu Fungi); ARN2 iron ion homeostasis; siderochrome metabolism; iron-siderochrome transport; endosome; plasma membrane; cytoplasmic vesicle; 11 ARN1 iron-siderochrome transport; endosome; cytoplasmic vesicle; 11 TIS11 04 ENB1 ferric-enterobactin transport; endosome; integral to membrane; cytoplasmic vesicle; 11 ### CLUSTER 27 ### 11 Cell rescue/Defense SPP2 nuclear mRNA splicing\, via spliceosome; spliceosome complex; 04 IBD2 mitotic spindle checkpoint; nucleus; SMP3 plasmid maintenance; 14 03 PDR5 drug transport; response to drug; plasma membrane; 01 13 11 PDR3 regulation of transcription from Pol II promoter; response to drug; nucleus; cytoplasm; 04 11 SNQ2 response to singlet oxygen; response to drug; plasma membrane; 11 01 13 YOR1 transport; response to drug; plasma membrane; PDR1 regulation of transcription from Pol II promoter; response to drug; nucleus; 04 11 ### CLUSTER 28 ### 00 Not clear YNR068C YLL049W BUD9 bud site selection; bud neck; 14 ### CLUSTER 29 ### 01 Metabolism YNR071C 01 YLR211C ### CLUSTER 30 ### 00 Not clear YDR042C YDL146W ### CLUSTER 31 ### 00 Not clear YPL206C POS5 NADPH biosynthesis; response to oxidative stress; mitochondrial matrix; ### CLUSTER 32 ### 00 Not clear YGR046W KRE29 ### CLUSTER 33 ### 00 Not clear YLL057C sulfur metabolism; 11 HXT8 hexose transport; plasma membrane; 01 08 ### CLUSTER 34 ### 03 Cell cycle & DNA processing YGL057C EST3 telomerase-dependent telomere maintenance; nucleus; telomerase holoenzyme complex; 03 ### CLUSTER 35 ### 01 Metabolism UTR2 cell wall organization and biogenesis; septin ring (sensu Saccharomyces); cell wall (sensu Fungi); ELO1 fatty acid elongation\, unsaturated fatty acid; membrane; 01 ### CLUSTER 36 ### 00 Not clear YPR203W YPR202W YFL067W YFL066C YFL065C YHL050C YHL049C YHR218W ASK10 transcription; 04 YFL064C YER189W YRF1-2 03 YEL075C YEL076C-A YEL076C YBL113C YBL112C YBL111C YEL077C HBT1 cellular morphogenesis during conjugation with cellular fusion; shmoo tip; 14 FIG2 cellular morphogenesis during conjugation with cellular fusion; cytogamy; cell wall (sensu Fungi); 14 YJL225C YIL177C PRY3 cell wall (sensu Fungi); 14 BAR1 protein catabolism; periplasmic space (sensu Fungi); 14 06 YHR219W YRF1-6 03 FKH2 regulation of cell cycle; G2-specific transcription in mitotic cell cycle; pseudohyphal growth; nucleus; 04 YMR317W YML133C YRF1-4 03 YLL067C BSC3 YRF1-3 YLR464W YLL066C YLR462W YRF1-1 03 ### CLUSTER 37 ### 08 Cellular transport YBR108W APL3 vesicle-mediated transport; AP-2 adaptor complex; 06 08 APS2 vesicle-mediated transport; AP-2 adaptor complex; 06 08 ### CLUSTER 38 ### 00 Not clear YBL108C-A YAR061W YAL064C-A YHR213W YAR062W ### CLUSTER 39 ### 00 Not clear YBR077C cytoplasm; PHO87 phosphate transport; membrane; 01 13 ### CLUSTER 40 ### 02 Energy YGR207C 02 MLS1 glyoxylate cycle; cytoplasm; peroxisomal matrix; 01 02 ### CLUSTER 41 ### 00 Not clear YHR192W NNT1 chromatin silencing at ribosomal DNA (rDNA); nicotinamide metabolism; ### CLUSTER 42 ### 00 Not clear YHR182W YHR151C ### CLUSTER 43 ### 06 Protein fate YCR100C 06 YCR099C 06 ### CLUSTER 44 ### 00 Not clear VTH1 Golgi to vacuole transport; 06 AAP1' 02 01 ### CLUSTER 45 ### 00 Not clear YDR020C 01 YNL058C AGA2 agglutination during conjugation with cellular fusion; cell wall (sensu Fungi); 14 ### CLUSTER 46 ### 04 Transcription/RNA processing/RNA transport YBL044W ITC1 chromatin modeling; negative regulation of transcription from Pol II promoter by pheromones; nucleus; 04 AIR2 mRNA-nucleus export; nucleus; 04 YIL161W ### CLUSTER 47 ### 00 Not clear RER1 ER to Golgi transport; COPII-coated vesicle; 06 PRM7 conjugation with cellular fusion; integral to membrane; YDL038C YBL095W CYK3 cytokinesis; ### CLUSTER 48 ### 01 Metabolism YOR186W MSC6 meiotic recombination; COX11 aerobic respiration; mitochondrial inner membrane; 01 06 SPE1 pantothenate biosynthesis; 01 COX3 aerobic respiration; respiratory chain complex IV (sensu Eukarya); 02 ### CLUSTER 49 ### 06 Protein fate UBC12 protein polyubiquitination; protein monoubiquitination; protein neddylation; 06 UBA1 ubiquitin cycle; nucleus; cytoplasm; 06 11 MRPL44 protein biosynthesis; mitochondrial large ribosomal subunit; 05 ### CLUSTER 50 ### 04 Transcription/RNA processing/RNA transport YPS7 PTR3 chemosensory perception; extrinsic to plasma membrane; 04 ### CLUSTER 51 ### 04 Transcription/RNA processing/RNA transport POP7 rRNA processing; tRNA processing; ribonuclease MRP complex; nucleolar ribonuclease P complex; 04 BCD1 snoRNA metabolism; FCY2 purine transport; cytosine transport; plasma membrane; 01 08 GDS1 aerobic respiration; AFT2 transcription initiation from Pol II promoter; iron ion homeostasis; response to oxidative stress; nucleus; RPP1 rRNA processing; tRNA processing; ribonuclease MRP complex; nucleolar ribonuclease P complex; 04 YGL242C LOT5 AKR2 08 MRPL37 protein biosynthesis; mitochondrial large ribosomal subunit; 05 LAG1 replicative cell aging; ceramide biosynthesis; endoplasmic reticulum; 14 01 06 HNM1 choline transport; plasma membrane; 08 ECM1 cell wall organization and biogenesis; FOB1 chromatin silencing at ribosomal DNA (rDNA); DNA recombination; extrachromosomal circular DNA accumulation during cell aging; nucleolus; 03 YBR030W phospholipid metabolism; 01 SUB2 U2-type nuclear mRNA branch site recognition; mRNA-nucleus export; transcription export complex; nucleus; spliceosome complex; 04 SQT1 ribosomal large subunit assembly and maintenance; cytoplasm; cytosol; cytosolic ribosome (sensu Eukarya); 06 DTD1 D-amino acid catabolism; 04 YLL007C YNR018W YBL054W 04 YGR079W RRP40 35S primary transcript processing; mRNA catabolism; nuclear exosome (RNase complex); cytoplasmic exosome (RNase complex); 03 DUS3 tRNA modification; YDR119W 11 NET1 chromatin silencing at ribosomal DNA (rDNA); nucleolus organization and biogenesis; regulation of exit from mitosis; nucleolus; 04 VMA4 vacuolar acidification; hydrogen-transporting ATPase V1 domain; vacuolar membrane (sensu Fungi); 08 13 06 BSC4 RPC25 transcription from Pol III promoter; DNA-directed RNA polymerase III complex; 04 FCY1 cytosine metabolism; 01 NOP58 rRNA modification; 35S primary transcript processing; processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; small nuclear ribonucleoprotein complex; 04 RPC31 transcription from Pol III promoter; DNA-directed RNA polymerase III complex; 04 RKI1 pentose-phosphate shunt; 01 02 ELP3 regulation of transcription from Pol II promoter; transcription elongation factor complex; DNA-directed RNA polymerase II\, holoenzyme; 03 06 RPO31 transcription from Pol III promoter; DNA-directed RNA polymerase III complex; 04 RPB8 transcription from Pol I promoter; transcription from Pol II promoter; transcription from Pol III promoter; DNA-directed RNA polymerase II\, core complex; DNA-directed RNA polymerase III complex; DNA-directed RNA polymerase I complex; 04 RPB10 transcription from Pol I promoter; transcription from Pol II promoter; transcription from Pol III promoter; DNA-directed RNA polymerase II\, core complex; DNA-directed RNA polymerase III complex; DNA-directed RNA polymerase I complex; 04 RET1 transcription from Pol III promoter; DNA-directed RNA polymerase III complex; 04 RPA190 transcription from Pol I promoter; DNA-directed RNA polymerase I complex; 04 YPL183C YPL207W YIL103W cytoplasm; TIF6 processing of 27S pre-rRNA; ribosomal large subunit biogenesis; nucleus; cytoplasm; 05 TBS1 04 NAN1 processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; 03 RPC37 transcription from Pol III promoter; DNA-directed RNA polymerase III complex; 04 FAR10 cell cycle arrest in response to pheromone; YER156C MAP1 proteolysis and peptidolysis; cytosolic ribosome (sensu Eukarya); 06 SUN4 mitochondrion organization and biogenesis; mitochondrial matrix; cell wall (sensu Fungi); 01 14 IDH2 tricarboxylic acid cycle; isocitrate metabolism; glutamate biosynthesis; mitochondrion; mitochondrial matrix; 01 04 02 KEL3 NIP7 ribosomal large subunit assembly and maintenance; rRNA processing; nucleolus; cytosolic large ribosomal subunit (sensu Eukarya); 04 NEW1 05 RPA135 transcription from Pol I promoter; DNA-directed RNA polymerase I complex; 04 BUD16 bud site selection; cytoplasm; TRM7 protein biosynthesis; tRNA methylation; cytoplasm; 04 MEU1 glutamate biosynthesis; cytoplasm; 01 FUR1 pyrimidine salvage; 01 DYS1 hypusine biosynthesis from peptidyl-lysine; 01 RPC19 transcription from Pol I promoter; transcription from Pol III promoter; DNA-directed RNA polymerase III complex; DNA-directed RNA polymerase I complex; 04 CDC54 pre-replicative complex formation and maintenance; DNA unwinding; DNA replication initiation; nucleus; pre-replicative complex; cytoplasm; 03 ADE12 adenosine biosynthesis; 01 CUP5 protein-vacuolar targeting; copper ion homeostasis; iron ion homeostasis; endocytosis; vacuole organization and biogenesis; vacuolar acidification; proton transport; hydrogen-transporting ATPase V0 domain; 08 13 11 PRE2 ubiquitin-dependent protein catabolism; proteasome core complex (sensu Eukarya); proteasome core complex\, beta-subunit complex (sensu Eukarya); 14 03 06 FHL1 rRNA processing; transcription from Pol III promoter; nucleus; 04 SRO7 exocytosis; Golgi to plasma membrane transport; cytosol; plasma membrane; 08 14 ISA2 iron ion transport; mitochondrial intermembrane space; 13 YPR091C NGL2 rRNA processing; intracellular; 02 RPS23B protein biosynthesis; regulation of translational fidelity; cytosolic small ribosomal subunit (sensu Eukarya); 05 SUI3 translational initiation; ribosome; 05 YLR243W YDR444W cytoplasm; 01 PRS5 histidine biosynthesis; tryptophan biosynthesis; purine salvage; 'de novo' IMP biosynthesis; 'de novo' pyrimidine base biosynthesis; 01 GIM5 tubulin folding; cytoplasm; 06 ACB1 fatty acid metabolism; long-chain fatty acid transport; 01 IKI3 regulation of transcription from Pol II promoter; transcription elongation factor complex; DNA-directed RNA polymerase II\, holoenzyme; YOR006C cytoplasm; RNA1 ribosome-nucleus export; rRNA-nucleus export; protein-nucleus import; rRNA metabolism; nucleus; cytosol; 04 SAM4 sulfur amino acid metabolism; RPO21 transcription from Pol II promoter; DNA-directed RNA polymerase II\, core complex; 04 RPB7 transcription from Pol II promoter; DNA-directed RNA polymerase II\, core complex; 04 11 RPB3 transcription from Pol II promoter; DNA-directed RNA polymerase II\, core complex; 04 RPB5 transcription from Pol I promoter; transcription from Pol II promoter; transcription from Pol III promoter; DNA-directed RNA polymerase II\, core complex; DNA-directed RNA polymerase III complex; DNA-directed RNA polymerase I complex; 04 RPB9 transcription from Pol II promoter; DNA-directed RNA polymerase II\, core complex; 04 RPB2 transcription from Pol II promoter; DNA-directed RNA polymerase II\, core complex; 04 RPB11 transcription from Pol II promoter; DNA-directed RNA polymerase II\, core complex; 04 RPB4 transcription from Pol II promoter; DNA-directed RNA polymerase II\, core complex; 04 11 UBP10 protein deubiquitination; nucleus; 04 06 YPL146C nucleus; nucleolus; YOR287C processing of 20S pre-rRNA; POP4 rRNA processing; tRNA processing; ribonuclease MRP complex; nucleolar ribonuclease P complex; 04 DIM1 rRNA modification; 35S primary transcript processing; nucleolus; 04 PUS1 tRNA modification; nucleus; 01 04 PET20 YOL029C ELP6 regulation of transcription from Pol II promoter; transcription elongation factor complex; 04 IKI1 regulation of transcription from Pol II promoter; transcription elongation factor complex; DNA-directed RNA polymerase II\, holoenzyme; ELP2 regulation of transcription from Pol II promoter; transcription elongation factor complex; 04 NOP4 rRNA processing; nucleolus; 04 UTP15 processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; SPL2 response to temperature; cytoplasm; RIO1 S phase of mitotic cell cycle; regulation of exit from mitosis; processing of 20S pre-rRNA; cytoplasm; NOG1 ribosome-nucleus export; nucleolus; PUS4 tRNA modification; nucleus; mitochondrion; 03 01 04 HST3 chromatin silencing at telomere; short-chain fatty acid metabolism; nucleus; 04 YOR315W PDE2 cAMP-mediated signaling; 01 YGR035C CLB5 regulation of CDK activity; G1/S transition of mitotic cell cycle; G2/M transition of mitotic cell cycle; premeiotic DNA synthesis; nucleus; 03 DSE3 DBP2 mRNA catabolism\, nonsense-mediated; 04 YOL125W RPC40 transcription from Pol I promoter; transcription from Pol III promoter; DNA-directed RNA polymerase III complex; DNA-directed RNA polymerase I complex; 04 RPC34 transcription from Pol III promoter; nucleus; DNA-directed RNA polymerase III complex; cytoplasm; 04 YHL039W YPL098C ELP4 regulation of transcription from Pol II promoter; cytoplasm; transcription elongation factor complex; 04 YGL082W RPC10 transcription from Pol I promoter; transcription from Pol II promoter; transcription from Pol III promoter; DNA-directed RNA polymerase II\, core complex; DNA-directed RNA polymerase III complex; DNA-directed RNA polymerase I complex; 04 SNP1 nuclear mRNA splicing\, via spliceosome; commitment complex; snRNP U1; 04 BUD13 bud site selection; nucleus; HSH49 nuclear mRNA splicing\, via spliceosome; snRNP U2; 04 MDN1 rRNA processing; protein complex assembly; nucleus; COG8 intra-Golgi transport; Golgi transport complex; 08 YKL014C PPM2 06 RPA43 transcription from Pol I promoter; DNA-directed RNA polymerase I complex; 04 YNR054C LYP1 basic amino acid transport; plasma membrane; 01 08 PUB1 mRNA catabolism\, nonsense-mediated; nucleus; cytoplasm; heterogeneous nuclear ribonucleoprotein complex; 04 FUN12 translational initiation; cytosolic small ribosomal subunit (sensu Eukarya); 05 YOL022C FOL1 folic acid and derivative biosynthesis; cytoplasm; 01 LEU9 leucine biosynthesis; mitochondrion; 01 YKL027W 01 MAE1 pyruvate metabolism; amino acid metabolism; mitochondrion; 01 YPL158C YOR154W TIP1 cell wall organization and biogenesis; cell wall (sensu Fungi); 01 11 TSR1 rRNA processing; ribosome biogenesis and assembly; nucleolus; GIR2 SRO9 protein biosynthesis; polysome; 13 04 NRP1 HGH1 YJR129C IFH1 chromatin silencing at telomere; rRNA processing; 04 MAK16 virus-host interaction; ribosomal large subunit biogenesis; nucleolus; 03 YDL063C RPC53 transcription from Pol III promoter; DNA-directed RNA polymerase III complex; 04 YBR271W YCR072C YBR267W DBP10 ribosomal large subunit assembly and maintenance; 35S primary transcript processing; nucleolus; 04 FYV7 processing of 20S pre-rRNA; DPH5 peptidyl-diphthamide biosynthesis from peptidyl-histidine; 01 BUD20 bud site selection; nucleus; UTP10 processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; MTR4 35S primary transcript processing; nucleolus; 04 08 YML108W RNT1 35S primary transcript processing; nucleolus; 04 BUD22 bud site selection; nucleus; YNL227C endocytosis; 06 GAR1 rRNA modification; 35S primary transcript processing; nucleolus; small nucleolar ribonucleoprotein complex; 04 CBF5 rRNA modification; 35S primary transcript processing; small nucleolar ribonucleoprotein complex; 14 04 03 YJR070C RPA12 transcription from Pol I promoter; DNA-directed RNA polymerase I complex; 04 DHR2 ribosome biogenesis; nucleolus; 04 DUS1 tRNA modification; DBP8 35S primary transcript processing; nucleolus; 04 SPB1 rRNA processing; nucleus; nucleolus; 04 05 YDR161W RRP1 rRNA processing; 04 BCP1 YDR339C YNL022C nucleus; YMR310C SIK1 rRNA modification; 35S primary transcript processing; processing of 20S pre-rRNA; nucleus; nucleolus; small nucleolar ribonucleoprotein complex; small nuclear ribonucleoprotein complex; 04 NOP2 rRNA processing; nucleolus; 04 RLP7 processing of 27S pre-rRNA; ribosomal large subunit biogenesis; nucleolus; IMP4 rRNA modification; 35S primary transcript processing; processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; small nuclear ribonucleoprotein complex; 04 NOP15 ribosomal large subunit biogenesis; nucleus; nucleolus; NOP13 nucleoplasm; nucleolus; 04 AAH1 adenine catabolism; 01 IPI3 GCD10 translational initiation; tRNA methylation; nucleus; 05 04 HAS1 nuclear membrane; nucleolus; 03 RRB1 ribosome biogenesis; nucleolus; 04 ERB1 rRNA processing; UTP14 processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; TSR2 processing of 20S pre-rRNA; RSA3 YLR003C regulation of DNA replication; DRS1 ribosomal large subunit assembly and maintenance; 35S primary transcript processing; nucleolus; 04 06 PWP1 UTP13 processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; 04 DBP9 ribosomal large subunit assembly and maintenance; 35S primary transcript processing; nucleolus; TRM2 tRNA modification; 04 RPF2 ribosomal large subunit assembly and maintenance; processing of 27S pre-rRNA; nucleolus; NOC3 DNA replication initiation; rRNA processing; nucleus; nucleolus; 06 RLP24 ribosomal large subunit biogenesis; nucleolus; 05 SOF1 rRNA modification; 35S primary transcript processing; processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; small nuclear ribonucleoprotein complex; 04 MPP10 rRNA modification; 35S primary transcript processing; processing of 20S pre-rRNA; nucleus; nucleolus; small nucleolar ribonucleoprotein complex; small nuclear ribonucleoprotein complex; 04 MRT4 rRNA processing; ribosomal large subunit biogenesis; 01 05 04 MAK11 virus-host interaction; ribosomal large subunit biogenesis; membrane fraction; 14 RPA34 transcription from Pol I promoter; nucleus; nucleolus; DNA-directed RNA polymerase I complex; 04 UTP30 UTP11 processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; LTV1 11 EBP2 rRNA processing; nucleolus; 04 EMG1 processing of 20S pre-rRNA; ribosomal small subunit biogenesis; nucleus; cytoplasm; UTP21 DIP2 processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; 03 PRP43 U2-type spliceosome dissembly; spliceosome complex; 04 PPT1 protein amino acid phosphorylation; nucleus; cytoplasm; LSG1 ribosome-nucleus export; conjugation with cellular fusion; sporulation (sensu Saccharomyces); cytoplasm; URA7 CTP biosynthesis; phospholipid biosynthesis; pyrimidine base biosynthesis; cytosol; 01 LHP1 tRNA processing; nucleus; nucleoplasm; nucleolus; 04 RRP3 35S primary transcript processing; nucleolus; 04 YIL096C YIL019W YIL127C GCD14 tRNA methylation; nucleus; 05 06 YJL122W UTP6 processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; 04 YDR365C UTP8 processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; 04 ARX1 ribosomal large subunit biogenesis; nucleoplasm; cytoplasm; 05 UTP5 processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; 04 SDA1 start control point of mitotic cell cycle; actin cytoskeleton organization and biogenesis; nucleus; 03 ATC1 response to stress; polar budding; nucleus; 13 UTP7 processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; 04 UTP9 processing of 20S pre-rRNA; nucleus; nucleolus; small nucleolar ribonucleoprotein complex; RIX1 ribosome-nucleus export; nucleoplasm; IMP3 rRNA modification; 35S primary transcript processing; ribosome biogenesis; processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; small nuclear ribonucleoprotein complex; 04 RPF1 ribosomal large subunit assembly and maintenance; processing of 27S pre-rRNA; nucleolus; SSF1 ribosomal large subunit assembly and maintenance; conjugation with cellular fusion; nucleolus; 14 CIC1 protein catabolism; proteasome complex (sensu Eukarya); nucleolus; PXR1 35S primary transcript processing; snRNA processing; nucleolus; 04 NMD3 ribosomal large subunit assembly and maintenance; cytosol; cytosolic large ribosomal subunit (sensu Eukarya); 04 TRM82 tRNA methylation; 04 MAK5 ribosomal large subunit assembly and maintenance; rRNA processing; nucleus; 04 YBL028C 14 RRP8 rRNA processing; nucleolus; 04 TRM1 tRNA methylation; nuclear outer membrane; mitochondrion; 04 TRM8 tRNA methylation; 04 SAS10 establishment and/or maintenance of chromatin architecture; processing of 20S pre-rRNA; nucleus; small nucleolar ribonucleoprotein complex; 04 NOP14 processing of 20S pre-rRNA; nucleus; nucleolus; small nucleolar ribonucleoprotein complex; 05 HMT1 mRNA-nucleus export; peptidyl-arginine modification; nucleus; 06 BFR2 ER to Golgi transport; 14 08 YDR412W rRNA processing; cytoplasm; SSF2 ribosomal large subunit assembly and maintenance; conjugation with cellular fusion; nucleolus; 14 ENP2 NSA2 ribosomal large subunit biogenesis; nucleus; 05 ROK1 35S primary transcript processing; nucleolus; 04 NSA1 ribosomal large subunit biogenesis; 05 DBP3 ribosomal large subunit assembly and maintenance; 35S primary transcript processing; nucleolus; 04 PUF6 NOP7 processing of 20S pre-rRNA; ribosomal large subunit biogenesis; nucleus; nucleolus; 05 NUG1 rRNA processing; nucleus; nucleolus; 08 05 ENP1 rRNA processing; cell growth and/or maintenance; processing of 20S pre-rRNA; nucleus; nucleolus; 06 YCR016W KRR1 rRNA processing; ribosome biogenesis; nucleolus; YGR272C processing of 20S pre-rRNA; LRP1 double-strand break repair via homologous recombination; double-strand break repair via nonhomologous end-joining; processing of 27S pre-rRNA; nuclear exosome (RNase complex); LOC1 ribosomal large subunit biogenesis; nucleus; CGR1 rRNA processing; ribosome biogenesis; nucleolus; SPB4 ribosomal large subunit assembly and maintenance; 35S primary transcript processing; nucleolus; 04 YJL010C NUC1 DNA catabolism; DNA recombination; RNA catabolism; mitochondrial inner membrane; 01 UTP4 processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; 04 DBP7 ribosomal large subunit assembly and maintenance; 35S primary transcript processing; nucleolus; 04 YLL034C YJR041C UTP18 YKR079C removal of tRNA 3'-trailer sequence; YER049W PRO1 proline biosynthesis; 01 YGR283C RVB1 regulation of transcription from Pol II promoter; nucleus; chromatin remodeling complex; 04 03 YHL013C YGR251W processing of 20S pre-rRNA; LCP5 rRNA modification; 35S primary transcript processing; small nucleolar ribonucleoprotein complex; small nuclear ribonucleoprotein complex; 04 YOR342C RRP12 ribosome biogenesis; processing of 20S pre-rRNA; ribosome; YTM1 chromosome organization and biogenesis (sensu Eukarya); ribosomal large subunit biogenesis; nucleus; nucleolus; 03 PNO1 rRNA processing; 35S primary transcript processing; protein complex assembly; nucleus; nucleolus; KRI1 ribosome biogenesis; nucleolus; YOR004W rRNA processing; processing of 20S pre-rRNA; NOB1 protein complex assembly; ubiquitin-dependent protein catabolism; proteasome complex (sensu Eukarya); nucleus; NOP12 rRNA metabolism; nucleolus; BRX1 ribosomal large subunit assembly and maintenance; nucleolus; YOL124C REX4 rRNA processing; ribosome assembly; 03 RCL1 rRNA processing; nucleolus; 04 NOG2 ribosomal large subunit-nucleus export; nucleus; nucleoplasm; nucleolus; KRE33 10 RRP6 35S primary transcript processing; nuclear exosome (RNase complex); RPA49 transcription from Pol I promoter; DNA-directed RNA polymerase I complex; 04 YNL313C PUS7 pseudouridine synthesis; NOC2 ribosome-nucleus export; ribosome assembly; nucleus; 08 RAI1 RNA catabolism; processing of 27S pre-rRNA; nucleus; YDR346C HCA4 35S primary transcript processing; nucleolus; 04 RRP14 nucleolus; 14 AIR1 mRNA-nucleus export; nucleus; nucleolus; 14 YLR051C YNL050C YMR269W YOR252W MOD5 tRNA modification; nucleus; nucleolus; mitochondrion; cytosol; 04 YNR024W BUD21 processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; YDR514C TRF4 DNA topological change; sister chromatid cohesion; mitotic chromosome condensation; nucleus; 03 YIL091C SRP40 nucleocytoplasmic transport; nucleolus; 04 MAK21 ribosomal large subunit assembly and maintenance; nucleus; nucleolus; 05 PWP2 establishment of cell polarity (sensu Saccharomyces); cytokinesis; processing of 20S pre-rRNA; small nucleolar ribonucleoprotein complex; cytoplasm; 03 14 RRP5 rRNA processing; processing of 20S pre-rRNA; nucleolus; nucleolus organizer complex; 04 PRS3 histidine biosynthesis; tryptophan biosynthesis; purine salvage; 'de novo' IMP biosynthesis; 'de novo' pyrimidine base biosynthesis; regulation of cell size; 01 GUA1 GMP metabolism; 01 NHP2 rRNA modification; 35S primary transcript processing; small nuclear ribonucleoprotein complex; 04 NOP6 response to dessication; NOP10 rRNA modification; 35S primary transcript processing; small nuclear ribonucleoprotein complex; 04 NOP1 ribosomal large subunit assembly and maintenance; rRNA modification; RNA methylation; 35S primary transcript processing; processing of 20S pre-rRNA; nucleolus; small nucleolar ribonucleoprotein complex; small nuclear ribonucleoprotein complex; 04 SFH5 phospholipid transport; microsome; cytosol; 01 PRS1 histidine biosynthesis; tryptophan biosynthesis; purine salvage; 'de novo' IMP biosynthesis; 'de novo' pyrimidine base biosynthesis; 01 14 NCL1 tRNA methylation; nucleus; 04 YOR091W cytoplasm; RMT2 peptidyl-arginine methylation; 01 YER007C-A FYV1 YGR093W PHO90 phosphate transport; membrane; 01 13 BPT1 cadmium ion transport; bilirubin transport; vacuolar membrane (sensu Fungi); 11 TOS4 PRS2 histidine biosynthesis; tryptophan biosynthesis; purine salvage; 'de novo' IMP biosynthesis; 'de novo' pyrimidine base biosynthesis; 01 PRS4 histidine biosynthesis; tryptophan biosynthesis; purine salvage; 'de novo' IMP biosynthesis; 'de novo' pyrimidine base biosynthesis; 01 SGD1 osmoregulation; nucleus; 13 RRN11 transcription from Pol I promoter; RNA polymerase I transcription factor complex; 04 YFL049W Q0032 AFG2 response to drug; intracellular; SHQ1 snoRNA metabolism; nucleoplasm; GEA1 ER to Golgi transport; intra-Golgi transport; Golgi vesicle; 08 NOP16 ribosomal large subunit biogenesis; nucleus; nucleolus; GIR1 FAL1 35S primary transcript processing; nucleolus; 04 YIL110W RPL22B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 YNL087W CEG1 mRNA capping; nucleus; 04 YLR287C TNA1 nicotinamide mononucleotide transport; integral to plasma membrane; SRP14 protein-ER targeting; signal recognition particle; 06 CWH36 cell wall organization and biogenesis; ENT1 actin cortical patch assembly; endocytosis; actin filament organization; actin cortical patch (sensu Saccharomyces); 08 YBR259W YAL018C CCT4 protein folding; cytoskeleton organization and biogenesis; cytoplasm; chaperonin-containing T-complex; cytoskeleton; 06 YDR520C YBR012C FAP7 response to oxidative stress; processing of 20S pre-rRNA; nucleus; 11 YBL036C amino acid metabolism; intracellular; GRX4 response to oxidative stress; intracellular; 11 06 RBS1 LCD1 DNA damage response\, signal transduction resulting in cell cycle arrest; telomerase-dependent telomere maintenance; establishment of protein localization; nuclear chromosome; 03 06 YOR051C nucleus; OGG1 DNA repair; base-excision repair\, AP site formation; mitochondrion; 03 GPI15 GPI anchor biosynthesis; YJR141W NOP8 ribosomal large subunit assembly and maintenance; rRNA processing; nucleolus; 06 YOR021C YJR003C HIS6 histidine biosynthesis; cell; 01 PRK1 actin cortical patch assembly; cytokinesis; protein amino acid phosphorylation; actin filament organization; actin cortical patch (sensu Saccharomyces); 03 PAN2 postreplication repair; mRNA processing; 05 04 YDR222W YBR235W 13 SHE1 SRD1 rRNA processing; 04 TFB4 transcription initiation from Pol II promoter; negative regulation of transcription from Pol II promoter\, mitotic; transcription factor TFIIH complex; 04 03 ATX2 manganese ion homeostasis; Golgi membrane; 11 13 FAS1 fatty acid biosynthesis; cytosol; fatty-acid synthase complex; 01 NAT5 protein amino acid acetylation; cytoplasm; ALG6 protein amino acid glycosylation; dolichol-linked oligosaccharide biosynthesis; endoplasmic reticulum; 01 06 LCB1 sphingolipid biosynthesis; membrane fraction; microsome; serine C-palmitoyltransferase complex; 01 IPI1 rRNA processing; PEX12 peroxisome organization and biogenesis; peroxisomal membrane; LCB3 calcium-mediated signaling; sphingolipid biosynthesis; endoplasmic reticulum; 11 01 CRR1 YOR175C YLR049C YJR030C YLR064W TEA1 transcription; nucleus; 04 RRN9 transcription from Pol I promoter; RNA polymerase I upstream activating factor complex; 04 RRN7 transcription from Pol I promoter; RNA polymerase I transcription factor complex; 04 RRN10 transcription from Pol I promoter; RNA polymerase I upstream activating factor complex; 04 RRN5 transcription from Pol I promoter; RNA polymerase I upstream activating factor complex; 04 RRN6 transcription from Pol I promoter; RNA polymerase I transcription factor complex; 04 RPC17 transcription initiation from Pol III promoter; DNA-directed RNA polymerase III complex; 04 ### CLUSTER 52 ### 03 Cell cycle & DNA processing YDR128W SLD2 DNA strand elongation; replication fork; 03 SAS4 chromatin silencing at telomere; nuclear chromosome\, telomeric region; nuclear chromatin; SAS2 chromatin silencing at telomere; nuclear chromosome\, telomeric region; nuclear chromatin; 14 03 04 CAC2 DNA repair; nucleosome assembly; chromatin silencing; chromosome\, pericentric region; chromatin assembly complex; 03 06 MSI1 DNA repair; nucleosome assembly; chromatin silencing; RAS protein signal transduction; chromatin silencing complex; chromatin assembly complex; 03 06 13 SAS5 chromatin silencing at telomere; nuclear chromosome\, telomeric region; nuclear chromatin; 03 04 ### CLUSTER 53 ### 01 Metabolism YHR155W 01 YGL108C PMT4 O-linked glycosylation; endoplasmic reticulum; 01 06 OAC1 sulfate transport; oxaloacetate transport; mitochondrial inner membrane; 08 PMT2 O-linked glycosylation; endoplasmic reticulum; 01 06 PMT1 O-linked glycosylation; endoplasmic reticulum membrane; 01 06 ### CLUSTER 54 ### 05 Protein synthesis FCY22 integral to membrane; 01 08 YIL090W RPE1 pentose-phosphate shunt; cytosol; 02 01 PPA1 vacuolar acidification; hydrogen-transporting ATPase V0 domain; HMI1 mitochondrial genome maintenance; mitochondrial matrix; 03 YLR281C TOM22 mitochondrial translocation; mitochondrial outer membrane translocase complex; 06 08 RPL11A ribosomal large subunit assembly and maintenance; protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 MAC1 cadmium ion homeostasis; regulation of protein catabolism; positive regulation of transcription from Pol II promoter; nucleus; 04 11 HTZ1 chromatin silencing at HML and HMR (sensu Saccharomyces); regulation of transcription from Pol II promoter; nuclear chromatin; chromatin assembly complex; SMF2 manganese ion transport; cytoplasmic vesicle; 08 06 FET4 low affinity iron ion transport; intracellular copper ion transport; integral to plasma membrane; 13 08 FET3 high affinity iron ion transport; plasma membrane; 13 08 CTR3 copper ion import; integral to plasma membrane; 13 YFR055W sulfur metabolism; copper ion homeostasis; 01 FRE2 iron ion transport; copper ion import; plasma membrane; 13 FRE1 iron ion transport; copper ion import; plasma membrane; 13 RCS1 high affinity iron ion transport; positive regulation of transcription from Pol II promoter; nucleus; cytoplasm; 13 04 FTR1 high affinity iron ion transport; plasma membrane; 13 CCC2 copper ion transport; intracellular copper ion transport; Golgi trans face; 13 SHU2 MTW1 chromosome segregation; spindle pole; 03 YGL160W membrane; 13 FRE6 13 RNH35 DNA replication; nucleus; 01 RFC1 leading strand elongation; DNA repair; mismatch repair; DNA replication factor C complex; 03 EXO1 mismatch repair; nucleus; 01 03 RIM13 protein processing; 06 14 FLX1 mitochondrial transport; mitochondrion; 01 08 CWC24 spliceosome complex; ILS1 protein biosynthesis; cytosol; 05 ARC1 tRNA-nucleus export; amino acid activation; cytoplasm; methionyl glutamyl tRNA synthetase complex; 04 MIS1 conversion of met-tRNAf to fmet-tRNA; nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism; mitochondrion; 01 KRS1 lysyl-tRNA aminoacylation; cytoplasm; 05 SHM1 one-carbon compound metabolism; mitochondrion; 01 SGN1 mRNA metabolism; cytoplasm; 04 HRB1 protein-nucleus import; nucleus; cytoplasm; heterogeneous nuclear ribonucleoprotein complex; 04 YGR250C TIF4632 translational initiation; ribosome; 05 YOL109W CWC21 spliceosome complex; TIF4631 translational initiation; ribosome; 05 NGR1 regulation of growth; cytoplasm; 14 04 SBP1 RNA metabolism; nucleolus; 04 SOL3 tRNA processing; pentose-phosphate shunt\, oxidative branch; 04 LCB2 sphingolipid biosynthesis; membrane fraction; microsome; serine C-palmitoyltransferase complex; 01 RRS1 rRNA processing; ribosome biogenesis; nucleus; 04 MMF1 mitochondrial genome maintenance; isoleucine biosynthesis; mitochondrion; mitochondrial matrix; EGD1 nascent polypeptide association; nascent polypeptide-associated complex; 04 01 06 YPL199C GCD1 translational initiation; ribosome; eukaryotic translation initiation factor 2B complex; 05 CDC33 regulation of cell cycle; translational initiation; nucleus; cytoplasm; ribosome; 14 05 GCD11 translational initiation; ribosome; 05 SPC24 microtubule nucleation; chromosome segregation; condensed nuclear chromosome kinetochore; condensed nuclear chromosome\, pericentric region; 03 MDM20 mitochondrion inheritance; cytoskeleton organization and biogenesis; N-terminal peptidyl-methionine acetylation; intracellular; 03 YOR073W SER1 L-serine biosynthesis; serine family amino acid biosynthesis; purine base biosynthesis; 01 YHR149C bud tip; bud neck; 14 GIS2 intracellular signaling cascade; 04 05 SUI1 translational initiation; ribosome; 05 SMI1 beta-1\,3 glucan biosynthesis; cell wall organization and biogenesis; nucleus; bud tip; 01 GIM3 tubulin folding; cytoplasm; 03 06 GCN2 regulation of translational initiation; protein amino acid phosphorylation; amino acid biosynthesis; cytosolic ribosome (sensu Eukarya); 05 GCD6 translational initiation; ribosome; eukaryotic translation initiation factor 2B complex; 05 GCD2 translational initiation; ribosome; eukaryotic translation initiation factor 2B complex; 05 SUI2 translational initiation; cytoplasm; ribosome; 05 GCN3 translational initiation; eukaryotic translation initiation factor 2B complex; 05 GCD7 translational initiation; ribosome; eukaryotic translation initiation factor 2B complex; 05 PHO88 phosphate transport; membrane; 01 BAT1 amino acid catabolism; branched chain family amino acid biosynthesis; mitochondrial matrix; 01 03 STM1 telomere maintenance; anti-apoptosis; nuclear telomere cap complex; cytoplasm; 01 10 THR4 threonine metabolism; 01 PDC6 ethanol metabolism; 01 02 PDC1 pyruvate metabolism; ethanol fermentation; 01 02 TDH2 gluconeogenesis; glycolysis; cytoplasm; lipid particle; cytosol; cell wall (sensu Fungi); 01 02 SSH1 cotranslational membrane targeting; translocon; endoplasmic reticulum membrane; nuclear envelope-endoplasmic reticulum network; 06 HXK2 fructose metabolism; nucleus; cytosol; 01 02 ZUO1 protein folding; cytoplasm; cytosol; ribosome; YLR022C 35S primary transcript processing; YMR178W SFA1 formaldehyde assimilation; 01 11 MAP2 proteolysis and peptidolysis; cytoplasm; 05 06 TIF1 translational initiation; ribosome; 05 SAM2 methionine metabolism; 01 RNQ1 cytosol; NPL3 mRNA-nucleus export; nucleus; cytoplasm; 04 08 06 FRS1 phenylalanyl-tRNA aminoacylation; phenylalanine-tRNA ligase complex; 05 TUB3 nuclear migration (sensu Saccharomyces); mitotic chromosome segregation; nuclear migration during conjugation with cellular fusion; homologous chromosome segregation; spindle pole body; polar microtubule; kinetochore microtubule; nuclear microtubule; cytoplasmic microtubule; 03 CRN1 actin filament organization; microtubule-based process; actin cortical patch (sensu Saccharomyces); 14 PMI40 cell wall mannoprotein biosynthesis; protein amino acid glycosylation; GDP-mannose biosynthesis; 01 FRS2 phenylalanyl-tRNA aminoacylation; cytoplasm; phenylalanine-tRNA ligase complex; 05 YER036C YNR021W YMR321C HTA1 chromatin assembly/disassembly; nuclear nucleosome; 04 KAP123 protein-nucleus import; nucleus; nuclear pore; cytoplasm; 06 08 ASP1 asparagine catabolism; intracellular; 01 YDR341C protein biosynthesis; cytoplasm; 05 FEN1 nonselective vesicle transport; sphingolipid biosynthesis; fatty acid elongation; endoplasmic reticulum; endoplasmic reticulum membrane; 01 14 EMP70 transport; membrane fraction; endosome; 08 AUR1 sphingolipid metabolism; Golgi apparatus; 01 TIF2 translational initiation; regulation of translational initiation; cytoplasm; ribosome; 05 SUR4 fatty acid biosynthesis; post-Golgi transport; sphingolipid biosynthesis; fatty acid elongation; endoplasmic reticulum; endoplasmic reticulum membrane; 01 14 SEC53 protein-ER targeting; cytosol; 01 06 URA5 pyrimidine base biosynthesis; cytoplasm; 01 MES1 amino acid activation; cytoplasm; 05 YHR020W 05 THS1 protein biosynthesis; cytoplasm; 01 05 DED81 asparaginyl-tRNA aminoacylation; cytoplasm; 05 YIL130W 04 RPS27A protein biosynthesis; cytoplasm; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS30A protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 YAR075W 01 IMD1 GTP biosynthesis; 01 YBR025C cytoplasm; SUP45 translational termination; cytosol; 05 ARO4 aromatic amino acid family biosynthesis; 01 YKL056C 05 RPS24B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 IMD2 GTP biosynthesis; 01 ASC1 cytoplasm; 02 05 RPS10B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL36A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 TIF11 translational initiation; ribosome; 05 RPS25B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPP0 ribosomal large subunit assembly and maintenance; protein biosynthesis; translational elongation; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL39 protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 BUD19 RPS14B ribosomal small subunit assembly and maintenance; protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL16A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS21A protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL40B protein biosynthesis; ubiquitin-dependent protein catabolism; cytosolic large ribosomal subunit (sensu Eukarya); 05 06 RPL17A protein biosynthesis; cytoplasm; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL8B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS22A protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL17B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS5 protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL43B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS4A protein biosynthesis; processing of 20S pre-rRNA; cytoplasm; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL14A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS0B ribosomal small subunit assembly and maintenance; protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 06 05 BUD28 RPL22A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL15A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS31 ribosomal small subunit assembly and maintenance; protein biosynthesis; cytoplasm; cytosolic small ribosomal subunit (sensu Eukarya); 05 06 RPL10 ribosomal large subunit assembly and maintenance; protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 06 03 TEF4 translational elongation; ribosome; 05 RPL37A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS28B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS7B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS3 protein biosynthesis; response to DNA damage stimulus; cytosolic small ribosomal subunit (sensu Eukarya); 05 YNL119W 05 RPL42A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL9B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL16B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL20A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS1B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS18B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS17A ribosomal small subunit assembly and maintenance; protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS16A protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL15B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL6A ribosomal large subunit assembly and maintenance; protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL13B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS22B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS29A protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL26A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS1A protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 14 RPL38 protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL6B ribosomal large subunit assembly and maintenance; protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL29 protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPP2B protein biosynthesis; translational elongation; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPP1A protein biosynthesis; translational elongation; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPP1B protein biosynthesis; translational elongation; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL41A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL31A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 GRS1 transcription termination; glycyl-tRNA aminoacylation; cytoplasm; mitochondrion; 05 RPL14B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL24A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL13A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL23A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS8A protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL19B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL32 protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL19A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS14A ribosomal small subunit assembly and maintenance; protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS29B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS6B protein biosynthesis; cytoplasm; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS9B protein biosynthesis; regulation of translational fidelity; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL21A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS11B ribosomal small subunit assembly and maintenance; protein biosynthesis; regulation of translational fidelity; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL27B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS26B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL23B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL2A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL34A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS24A protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL12A ribosomal large subunit assembly and maintenance; protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL37B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS13 protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS11A ribosomal small subunit assembly and maintenance; protein biosynthesis; regulation of translational fidelity; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS18A protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS17B ribosomal small subunit assembly and maintenance; protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL12B ribosomal large subunit assembly and maintenance; protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS8B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL4B protein biosynthesis; cytoplasm; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL35B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL35A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS16B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL4A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS26A protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS2 protein biosynthesis; regulation of translational fidelity; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL24B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL8A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL34B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL2B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS4B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL42B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL27A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS27B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS21B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL40A protein biosynthesis; ubiquitin-dependent protein catabolism; cytosolic large ribosomal subunit (sensu Eukarya); 05 06 RPS20 protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS25A protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL7A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL30 rRNA processing; protein biosynthesis; negative regulation of translation; negative regulation of nuclear spliceosomal mRNA splicing; cytoplasm; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL9A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL1B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL28 protein biosynthesis; nucleus; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS23A protein biosynthesis; regulation of translational fidelity; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL26B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL11B ribosomal large subunit assembly and maintenance; protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS0A ribosomal small subunit assembly and maintenance; protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 14 05 06 SNU13 nuclear mRNA splicing\, via spliceosome; processing of 20S pre-rRNA; nucleolus; small nucleolar ribonucleoprotein complex; small nuclear ribonucleoprotein complex; 04 IMD3 GTP biosynthesis; cytoplasm; 01 APT1 AMP biosynthesis; 01 RPS30B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPP2A protein biosynthesis; translational elongation; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL18B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 SSB2 protein biosynthesis; cytoplasm; polysome; 05 RPS19B protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS15 protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL33B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS7A protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS28A protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPS19A protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL25 ribosomal large subunit assembly and maintenance; protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL3 ribosomal large subunit assembly and maintenance; protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL18A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 WRS1 tryptophanyl-tRNA aminoacylation; cytoplasm; 05 RPS12 protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL21B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS10A protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL20B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 CAF20 negative regulation of translation; mRNA cap complex; 05 RPL5 ribosomal large subunit assembly and maintenance; protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS6A protein biosynthesis; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL33A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPS9A protein biosynthesis; regulation of translational fidelity; cytoplasm; cytosolic small ribosomal subunit (sensu Eukarya); 05 BRE5 TIF5 regulation of translational initiation; mature ribosome assembly; cytosolic small ribosomal subunit (sensu Eukarya); 05 RPL43A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 RPL7B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 CDC60 leucyl-tRNA aminoacylation; cytoplasm; 05 RPL1A protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 PRE10 ubiquitin-dependent protein catabolism; proteasome core complex (sensu Eukarya); 06 YEF3 translational elongation; ribosome; 05 IMD4 01 PTH2 protein biosynthesis; cytoplasm; 05 YSY6 protein secretion; 06 08 EFB1 translational elongation; ribosome; 05 ERP1 ER to Golgi transport; COPII-coated vesicle; 06 08 YMR003W HHF2 chromatin assembly/disassembly; nuclear nucleosome; 04 VPS75 protein-vacuolar targeting; 03 HTA2 chromatin assembly/disassembly; nuclear nucleosome; 04 HTB2 chromatin assembly/disassembly; nuclear nucleosome; 04 HTB1 chromatin assembly/disassembly; nuclear nucleosome; 04 HHT1 chromatin assembly/disassembly; nuclear nucleosome; nucleus; 04 SRP102 protein-ER targeting; integral to endoplasmic reticulum membrane; 06 HEK2 telomerase-dependent telomere maintenance; mRNA localization\, intracellular; nuclear chromosome\, telomeric region; cytoplasm; 03 HAT2 chromatin assembly/disassembly; chromatin silencing at telomere; nucleus; cytoplasm; 04 06 RPL31B protein biosynthesis; cytosolic large ribosomal subunit (sensu Eukarya); 05 MGA2 fatty acid metabolism; response to cold; positive regulation of transcription from Pol II promoter; endoplasmic reticulum membrane; 03 ILV1 branched chain family amino acid biosynthesis; 01 CDC55 protein biosynthesis; protein amino acid dephosphorylation; actin filament organization; mitotic spindle checkpoint; bud growth; pseudohyphal growth; protein phosphatase type 2A complex; 14 03 11 YGR001C TOS1 POP6 rRNA processing; tRNA processing; ribonuclease MRP complex; nucleolar ribonuclease P complex; 04 GBP2 telomere maintenance; poly(A)+ mRNA-nucleus export; nucleus; ELF1 cell growth; SSP2 spore wall assembly (sensu Saccharomyces); spore wall (sensu Fungi); SUA5 cell growth and/or maintenance; 05 POL5 DNA dependent DNA replication; nucleolus; PIB2 vesicle-mediated transport; late endosome; BUD27 bud site selection; 14 SSZ1 protein biosynthesis; cytoplasm; 11 SUT1 regulation of transcription from Pol II promoter; sterol transport; nucleus; 01 ZPR1 regulation of cell cycle; nucleolus; cytoplasm; ERV1 iron ion homeostasis; mitochondrion organization and biogenesis; mitochondrion; mitochondrial intermembrane space; 03 RPA14 transcription from Pol I promoter; DNA-directed RNA polymerase I complex; 04 YOR286W 06 TAD3 tRNA modification; 04 TRX3 response to oxidative stress; mitochondrion; 11 LIT2 04 TRX1 vacuole inheritance; DNA dependent DNA replication; response to oxidative stress; regulation of redox homeostasis; vacuole fusion (non-autophagic); vacuole (sensu Fungi); cytosol; 03 06 11 MMT1 iron ion homeostasis; mitochondrion; integral to membrane; 13 YGR277C coenzyme A biosynthesis; intracellular; YDR210W YCR090C MRS6 intracellular protein transport; cytoplasm; membrane; 06 14 01 HNT3 MET10 sulfate assimilation; sulfite reductase complex (NADPH); 01 NNF2 membrane fraction; MKT1 viral life cycle; SCW10 conjugation with cellular fusion; cytoplasm; endoplasmic reticulum; cell wall (sensu Fungi); REX2 RNA processing; mitochondrion; 04 RHK1 protein amino acid glycosylation; dolichol-linked oligosaccharide biosynthesis; endoplasmic reticulum; 01 06 TIR4 cell wall (sensu Fungi); 11 EFT2 translational elongation; ribosome; 05 SED1 cell wall organization and biogenesis; ribosome; cell wall (sensu Fungi); 11 VPS35 retrograde (endosome to Golgi) transport; protein-Golgi retention; endosome; 06 08 PEP8 retrograde (endosome to Golgi) transport; protein-Golgi retention; endosome; 06 VPS29 retrograde (endosome to Golgi) transport; endosome; 08 06 GAS4 cell wall (sensu Fungi); ALG9 protein amino acid glycosylation; dolichol-linked oligosaccharide biosynthesis; endoplasmic reticulum; 01 VPS5 retrograde (endosome to Golgi) transport; protein-Golgi retention; endosome; 06 YJR111C ATP10 protein complex assembly; mitochondrial membrane; 06 YHM2 tricarboxylic acid transport; mitochondrial inner membrane; 03 LAP3 response to antibiotic; cytoplasm; 11 06 FUM1 tricarboxylic acid cycle; fumarate metabolism; mitochondrial matrix; cytosol; 02 IDP1 isocitrate metabolism; glutamate biosynthesis; mitochondrion; 01 02 KTR1 cell wall mannoprotein biosynthesis; N-glycan processing; O-linked glycosylation; Golgi apparatus; 01 06 GCR1 positive regulation of glycolysis; positive regulation of transcription from Pol II promoter; nucleus; 01 04 CAM1 regulation of translational elongation; cytosolic ribosome (sensu Eukarya); 05 ERG10 ergosterol biosynthesis; cytosol; 01 TEF2 translational elongation; ribosome; 05 SRP21 protein-ER targeting; nucleus; signal recognition particle; 06 SEC65 SRP-dependent cotranslational membrane targeting\, signal sequence recognition; signal recognition particle; 06 SUA7 transcription initiation from Pol II promoter; nucleoplasm; 04 PEX6 peroxisome organization and biogenesis; peroxisome; 06 HSP82 protein folding; response to stress; cytoplasm; 02 03 14 11 SRP72 protein-ER targeting; signal recognition particle; 06 SRP68 protein-ER targeting; signal recognition particle; 06 YNL247W cysteinyl-tRNA aminoacylation; cysteine metabolism; 05 BFR1 cytokinesis; spindle assembly; regulation of mitosis; bud growth; meiosis; polysome; nuclear envelope-endoplasmic reticulum network; 14 03 ALA1 alanyl-tRNA aminoacylation; cytoplasm; 05 HTS1 histidyl-tRNA aminoacylation; cytoplasm; mitochondrion; 05 GAS1 cell wall organization and biogenesis; plasma membrane; 01 CCT6 protein folding; cytoskeleton organization and biogenesis; cytoplasm; cytoskeleton; 06 FPR4 nucleus; 06 NIT2 01 GDH1 glutamate biosynthesis\, using glutamate dehydrogenase (NAD(P)+); nucleus; cytoplasm; 01 ATR1 multidrug transport; plasma membrane; 11 URE2 regulation of nitrogen utilization; soluble fraction; 01 PUT1 glutamate biosynthesis; proline catabolism; mitochondrion; 01 CAR2 arginine catabolism; cytoplasm; 01 ALG7 N-linked glycosylation; endoplasmic reticulum; 03 06 01 YMR279C 11 SEC59 protein amino acid glycosylation; protein-ER targeting; membrane; 01 14 YOR285W 06 SPT14 GPI anchor biosynthesis; endoplasmic reticulum; 01 HXT11 hexose transport; plasma membrane; 01 08 NIT3 01 FDH2 formate catabolism; 02 CPA1 arginine biosynthesis; cytosol; 01 UBA2 protein sumoylation; nucleus; 06 04 SMT3 protein sumoylation; nucleus; septin ring; 06 ADH1 fermentation; cytosol; 01 02 YGL179C YLR218C TSA1 response to oxidative stress; regulation of redox homeostasis; cytoplasm; 11 YOL014W MCD4 GPI anchor biosynthesis; ATP transport; vacuole (sensu Fungi); cell wall (sensu Fungi); 14 PUT4 neutral amino acid transport; plasma membrane; 08 01 SES1 amino acid activation; cytoplasm; 05 HCS1 lagging strand elongation; alpha DNA polymerase\:primase complex; 03 CAR1 arginine catabolism to ornithine; cytosol; 01 BNI4 cytokinesis; contractile ring (sensu Saccharomyces); 06 14 BIO4 biotin biosynthesis; cytoplasm; 01 TRM3 tRNA methylation; 04 STE23 proteolysis and peptidolysis; peptide pheromone maturation; integral to membrane; 14 06 SMM1 tRNA modification; tRNA processing; SKI7 mRNA catabolism; exosome (RNase complex); cytoplasm; 01 VAS1 valyl-tRNA aminoacylation; cytoplasm; mitochondrion; 05 GLN4 amino acid activation; cytoplasm; 05 SCP160 chromosome segregation; mRNA localization\, intracellular; endoplasmic reticulum membrane; polysome; nuclear envelope-endoplasmic reticulum network; 03 PKR1 YOR271C FUS2 plasma membrane fusion; shmoo tip; 14 YLR118C SUL2 sulfate transport; plasma membrane; 13 01 YOR246C YOL098C IMP1 mitochondrial processing; mitochondrial inner membrane peptidase complex; 06 CSG2 calcium ion homeostasis; integral to endoplasmic reticulum membrane; 01 ZTA1 OSH1 steroid biosynthesis; Golgi trans cisterna; early endosome; endoplasmic reticulum; 01 03 ASP3-2 asparagine catabolism; cellular response to nitrogen starvation; periplasmic space (sensu Fungi); 01 ASP3-1 asparagine catabolism; cellular response to nitrogen starvation; nuclear membrane; endoplasmic reticulum; periplasmic space (sensu Fungi); 01 KRE9 beta-1\,6 glucan metabolism; cell wall organization and biogenesis; extracellular; 14 01 KRE1 cell wall organization and biogenesis; cell wall (sensu Fungi); 01 SKN1 beta-1\,6 glucan biosynthesis; cell wall organization and biogenesis; integral to membrane; 01 KRE11 ER to Golgi transport; TRAPP; 01 08 CWH41 cell wall organization and biogenesis; endoplasmic reticulum membrane; 01 MOB1 protein amino acid phosphorylation; regulation of exit from mitosis; bud neck; 03 04 GLC3 glycogen metabolism; 02 01 BUR2 mitotic chromosome segregation; transcription; 04 03 DST1 RNA elongation from Pol II promoter; meiotic recombination; nucleoplasm; 04 03 YGL211W MCM6 DNA unwinding; DNA replication initiation; nucleus; pre-replicative complex; cytoplasm; 03 YGL262W PUP2 ubiquitin-dependent protein catabolism; response to stress; sporulation (sensu Saccharomyces); proteasome core complex (sensu Eukarya); proteasome core complex\, alpha-subunit complex (sensu Eukarya); 03 11 06 14 DIN7 DNA repair; mitochondrion; 11 YEN1 nucleus; FAB1 phospholipid metabolism; response to stress; vacuole organization and biogenesis; vacuolar membrane; 01 08 06 YDR115W aerobic respiration; mitochondrial large ribosomal subunit; 05 MRPL25 protein biosynthesis; mitochondrial large ribosomal subunit; 05 PTH1 protein biosynthesis; 05 CCT8 protein folding; cytoskeleton organization and biogenesis; cytoplasm; cytoskeleton; 06 GUK1 GMP metabolism; 01 UBA4 protein modification; 06 RPC11 transcription from Pol III promoter; DNA-directed RNA polymerase III complex; 04 YKE2 protein folding; tubulin folding; cytoplasm; 06 YBR246W GSF2 secretory pathway; cytoplasm; integral to endoplasmic reticulum membrane; 01 SPT15 transcription from Pol I promoter; transcription initiation from Pol II promoter; transcription initiation from Pol III promoter; RNA polymerase I transcription factor complex; transcription factor TFIIIB complex; nucleus; transcription factor TFIID complex; 04 MRP20 protein biosynthesis; mitochondrial large ribosomal subunit; 05 NBP1 nucleus; CST9 DNA replication and chromosome cycle; synaptonemal complex formation; nuclear chromosome; 03 SDS22 protein targeting; chromosome segregation; nucleus; cytoplasm; 03 06 ASI1 ubiquitin-dependent protein catabolism; endoplasmic reticulum membrane; HHF1 chromatin assembly/disassembly; nuclear nucleosome; 04 PKC1 protein amino acid phosphorylation; actin filament organization; cell wall organization and biogenesis; signal transduction; protein kinase cascade; site of polarized growth (sensu Saccharomyces); 03 14 11 IPP1 phosphate metabolism; cytosol; 01 YBR013C KAR4 karyogamy during conjugation with cellular fusion; mitosis; meiosis; positive regulation of transcription from Pol II promoter; nucleus; 14 04 03 SED4 ER to Golgi transport; endoplasmic reticulum; 08 HCM1 transcription initiation from Pol II promoter; spindle assembly; nucleus; 04 PSA1 cell wall mannoprotein biosynthesis; protein amino acid glycosylation; GDP-mannose biosynthesis; cytoplasm; 01 HMF1 nucleus; cytoplasm; cytosol; 11 ERG8 ergosterol biosynthesis; isoprenoid biosynthesis; cytosol; 01 CMD1 cytoskeleton organization and biogenesis; mitosis; budding; incipient bud site; cytoplasm; central plaque of spindle pole body; bud tip; bud neck; shmoo tip; 14 08 03 YJL046W SCM4 cell cycle; 03 FEN2 pantothenate transport; plasma membrane; 01 HEM13 heme biosynthesis; mitochondrial inner membrane; 01 CYC7 electron transport; mitochondrial intermembrane space; 11 02 ERG2 ergosterol biosynthesis; endoplasmic reticulum; 01 ERG12 ergosterol biosynthesis; cytosol; 01 DLD1 carbohydrate metabolism; aerobic respiration; mitochondrial inner membrane; 02 01 MVD1 ergosterol biosynthesis; isoprenoid biosynthesis; cytosol; 01 COX15 heme a biosynthesis; cytochrome c oxidase biogenesis; mitochondrial inner membrane; 02 06 YIG2 PET111 protein biosynthesis; mitochondrial inner membrane; 05 COX5A aerobic respiration; respiratory chain complex IV (sensu Eukarya); 02 YMR171C MMS22 double-strand break repair; YMR134W iron ion homeostasis; cytoplasm; NDE1 NADH oxidation; ethanol fermentation; mitochondrion; 02 RIP1 mitochondrial electron transport\, ubiquinol to cytochrome c; aerobic respiration; respiratory chain complex III (sensu Eukarya); 02 PET10 aerobic respiration; lipid particle; 03 02 ERG9 ergosterol biosynthesis; endoplasmic reticulum; 01 YDL086W cytoplasm; ERG26 ergosterol biosynthesis; endoplasmic reticulum; endoplasmic reticulum membrane; 01 ERG7 ergosterol biosynthesis; endoplasmic reticulum; lipid particle; plasma membrane; 01 ERG1 ergosterol biosynthesis; endoplasmic reticulum; lipid particle; 01 HYP2 translational initiation; cytoplasm; ribosome; 05 01 ERG28 ergosterol biosynthesis; endoplasmic reticulum membrane; 01 CYC1 electron transport; mitochondrial intermembrane space; 02 ERG3 ergosterol biosynthesis; endoplasmic reticulum; 01 ERG6 ergosterol biosynthesis; endoplasmic reticulum; lipid particle; 01 ACS2 acetyl-CoA biosynthesis; cytosol; 01 02 ERG13 ergosterol biosynthesis; mitochondrion; endoplasmic reticulum; 01 ANB1 translational initiation; ribosome; 05 HMG1 ergosterol biosynthesis; nuclear membrane; mitochondrial matrix; endoplasmic reticulum membrane; 01 ERG5 ergosterol biosynthesis; endoplasmic reticulum; 11 01 HMX1 iron ion homeostasis; membrane; 01 ERG4 ergosterol biosynthesis; endoplasmic reticulum; 01 ERG11 ergosterol biosynthesis; endoplasmic reticulum; 11 01 YGL140C QCR7 mitochondrial electron transport\, ubiquinol to cytochrome c; aerobic respiration; cytochrome bc(1) complex biogenesis; respiratory chain complex III (sensu Eukarya); 06 02 COX9 aerobic respiration; respiratory chain complex IV (sensu Eukarya); 02 06 COX4 aerobic respiration; respiratory chain complex IV (sensu Eukarya); 02 COX6 aerobic respiration; respiratory chain complex IV (sensu Eukarya); 02 COX13 aerobic respiration; respiratory chain complex IV (sensu Eukarya); 02 COX5B anaerobic respiration; respiratory chain complex IV (sensu Eukarya); 02 COX8 aerobic respiration; respiratory chain complex IV (sensu Eukarya); 02 ATP7 protein complex assembly; ATP synthesis coupled proton transport; proton-transporting ATP synthase\, stator stalk (sensu Eukarya); 13 02 08 ECM13 cell wall organization and biogenesis; YLL012W 01 HRD3 ER-associated protein catabolism; endoplasmic reticulum; 06 HMG2 ergosterol biosynthesis; nuclear membrane; mitochondrial matrix; endoplasmic reticulum membrane; 01 YJL107C PRM10 conjugation with cellular fusion; integral to membrane; MMR1 SAH1 methionine metabolism; selenocysteine metabolism; 01 YJL051W SBE22 cell wall organization and biogenesis; 14 MSC7 meiotic recombination; 02 FCY21 integral to membrane; 01 08 GDA1 protein amino acid glycosylation; Golgi apparatus; 06 FUI1 uridine transport; plasma membrane; 01 HAP3 regulation of carbohydrate metabolism; transcription; CCAAT-binding factor complex; 04 HAP2 regulation of carbohydrate metabolism; transcription; nucleus; CCAAT-binding factor complex; 04 PSY2 01 ARE1 sterol metabolism; endoplasmic reticulum; 01 14 MYO4 mRNA localization\, intracellular; actin cap (sensu Saccharomyces); 14 03 08 YJL048C SHE3 mRNA localization\, intracellular; actin cap (sensu Saccharomyces); cytoplasm; 14 YAR064W GCN20 regulation of translational elongation; cytosol; cytosolic ribosome (sensu Eukarya); 05 YML079W MAM3 mitochondrion organization and biogenesis; hemolysis; ECM3 cell wall organization and biogenesis; LSC2 tricarboxylic acid cycle; succinyl-CoA metabolism; mitochondrion; 01 02 TPN1 vitamin/cofactor transport; plasma membrane; 01 YER186C YDR539W SHE10 CBP6 protein biosynthesis; mitochondrion; 05 04